Reconstitution of human microglia and resident T cells in the brain of humanized DRAGA mice von Ghosh Roy, Sounak, Karim, Ahmad F, Brumeanu, Teodor-D, Casares, Sofia A

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Human-Immune-System (HIS) humanized mouse model (DRAGA: HLA-A2.HLA-DR4.Rag1KO.IL-2RγcKO.NOD) for COVID-19 von Brumeanu, Teodor-D., Vir, Pooja, Karim, Ahmad Faisal, Kar, Swagata, Benetiene, Dalia, Lok, Megan, Greenhouse, Jack, Putmon-Taylor, Tammy, Kitajewski, Christopher, Chung, Kevin K., Pratt, Kathleen P., Casares, Sofia A.

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The humanized DRAGA mouse (HLA-A2. HLA-DR4. RAG1 KO. IL-2R g c KO. NOD) establishes inducible and transmissible models for influenza type A infections von Mendoza, Mirian, Gunasekera, Devi, Pratt, Kathleen P., Qiu, Qi, Casares, Sofia, Brumeanu, Teodor-D.

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Humanized DRAGA mice immunized with Plasmodium falciparum sporozoites and chloroquine elicit protective pre-erythrocytic immunity von Majji, Sai, Wijayalath, Wathsala, Shashikumar, Soumya, Brumeanu, Teodor D, Casares, Sofia

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Generation and testing anti-influenza human monoclonal antibodies in a new humanized mouse model (DRAGA: HLA-A2. HLA-DR4. Rag1 KO. IL-2Rγc KO. NOD) von Mendoza, Mirian, Ballesteros, Angela, Qiu, Qi, Pow Sang, Luis, Shashikumar, Soumya, Casares, Sofia, Brumeanu, Teodor-D.

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Differential effect of HLA class-I versus class-II transgenes on human T and B cell reconstitution and function in NRG mice von Majji, Sai, Wijayalath, Wathsala, Shashikumar, Soumya, Pow-Sang, Luis, Villasante, Eileen, Brumeanu, Teodor D., Casares, Sofia

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Nonobese Diabetic (NOD) Mice Lack a Protective B-Cell Response against the “Nonlethal” Plasmodium yoelii 17XNL Malaria Protozoan von Mendoza, Mirian, Pow Sang, Luis, Qiu, Qi, Casares, Sofia, Brumeanu, Teodor-D.

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Humanized HLA-DR4.RagKO.IL2RγcKO.NOD (DRAG) mice sustain the complex vertebrate life cycle of Plasmodium falciparum malaria von Wijayalath, Wathsala, Majji, Sai, Villasante, Eileen F, Brumeanu, Teodor D, Richie, Thomas L, Casares, Sofia

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Down-regulation of autoreactive T-cells by HMG CoA reductase inhibitors von Brumeanu, Teodor-D., Goldstein, Robert, Casares, Sofia

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Differential effect of CD4+ Foxp3+ T-regulatory cells on the B and T helper cell responses to influenza virus vaccination von Surls, Jacqueline, Nazarov-Stoica, Cristina, Kehl, Margaret, Casares, Sofia, Brumeanu, Teodor-D

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Soluble, dimeric HLA DR4‐peptide chimeras: An approach for detection and immunoregulation of human type‐1 diabetes von Preda, Ioana, McEvoy, Robert C., Lin, Marvin, Bona, Constantin A., Rapaport, Robert, Brumeanu, Teodor D., Casares, Sofia

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Efficacy of clonal deletion vs. anergy of self-reactive CD4 T-cells for the prevention and reversal of autoimmune diabetes von Preda-Pais, Anca, Stan, Alexandru C., Casares, Sofia, Bona, Constantin, Brumeanu, Teodor-D.

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Analysis of lipid rafts in T cells von Thomas, Sunil, Preda-Pais, Anca, Casares, Sofia, Brumeanu, Teodor-D

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Immunopotency of a viral peptide assembled on the carbohydrate moieties of self immunoglobulins von Brumeanu, Teodor-D, Casares, Sofia, Harris, Paul E, Dehazya, Philip, Wolf, Imre, Boehmer, Harold von, Bona, Constantin A

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Double Negative (CD3+4−8−) TCRαβ Splenic Cells from Young NOD Mice Provide Long-Lasting Protection against Type 1 Diabetes von Duncan, Beverly, Nazarov–Stoica, Cristina, Surls, Jacqueline, Kehl, Margaret, Bona, Constantin, Casares, Sofia, Brumeanu, Teodor-D.

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Double negative (CD3+ 4- 8-) TCR alphabeta splenic cells from young NOD mice provide long-lasting protection against type 1 diabetes von Duncan, Beverly, Nazarov-Stoica, Cristina, Surls, Jacqueline, Kehl, Margaret, Bona, Constantin, Casares, Sofia, Brumeanu, Teodor-D

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Humanized HLA-DR4.RagKO.IL2R[gamma]cKO.NOD mice sustain the complex vertebrate life cycle of Plasmodium falciparum malaria von Wijayalath, Wathsala, Majji, Sai, Villasante, Eileen F, Brumeanu, Teodor D, Richie, Thomas L, Casares, Sofia

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Humanized HLA-DR4 Mice Fed with the Protozoan Pathogen of Oysters Perkinsus Marinus von Wijayalath, Wathsala, Majji, Sai, Kleschenko, Yuliya, Pow-Sang, Luis, Brumeanu, Teodor D, Villasante, Eileen Franke, Vasta, Gerardo R, Fernández-Robledo, José-Antonio, Casares, Sofia

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Presentation of a viral peptide assembled on the carbohydrate moieties of immunoglobulin does not require processing von Brumeanu, Teodor‐D., Casares, Sofia, Dehazya, Philip, Bot, Simona, Bona, Constantin A.

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A model for antigen-specific T-cell anergy: displacement of CD4-p56(lck) signalosome from the lipid rafts by a soluble, dimeric peptide-MHC class II chimera von Thomas, Sunil, Kumar, Rajeev, Preda-Pais, Anca, Casares, Sofia, Brumeanu, Teodor-D

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