Large Neutral Amino Acid Supplementation Exerts Its Effect through Three Synergistic Mechanisms: Proof of Principle in Phenylketonuria Mice von van Vliet, Danique, Bruinenberg, Vibeke M, Mazzola, Priscila N, van Faassen, Martijn H J R, de Blaauw, Pim, Kema, Ido P, Heiner-Fokkema, M Rebecca, van Anholt, Rogier D, van der Zee, Eddy A, van Spronsen, Francjan J

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Sleep deprivation causes memory deficits by negatively impacting neuronal connectivity in hippocampal area CA1 von Havekes, Robbert, Park, Alan J, Tudor, Jennifer C, Luczak, Vincent G, Hansen, Rolf T, Ferri, Sarah L, Bruinenberg, Vibeke M, Poplawski, Shane G, Day, Jonathan P, Aton, Sara J, Radwańska, Kasia, Meerlo, Peter, Houslay, Miles D, Baillie, George S, Abel, Ted

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Transiently increasing cAMP levels selectively in hippocampal excitatory neurons during sleep deprivation prevents memory deficits caused by sleep loss von Havekes, Robbert, Bruinenberg, Vibeke M, Tudor, Jennifer C, Ferri, Sarah L, Baumann, Arnd, Meerlo, Peter, Abel, Ted

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Long-term dietary intervention with low Phe and/or a specific nutrient combination improve certain aspects of brain functioning in phenylketonuria (PKU) von Bruinenberg, Vibeke M, van Vliet, Danique, van der Goot, Els, Counotte, Danielle S, Kuhn, Mirjam, van Spronsen, Francjan J, van der Zee, Eddy A

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Compartmentalized PDE4A5 Signaling Impairs Hippocampal Synaptic Plasticity and Long-Term Memory von Havekes, Robbert, Park, Alan J, Tolentino, Rosa E, Bruinenberg, Vibeke M, Tudor, Jennifer C, Lee, Yool, Hansen, Rolf T, Guercio, Leonardo A, Linton, Edward, Neves-Zaph, Susana R, Meerlo, Peter, Baillie, George S, Houslay, Miles D, Abel, Ted

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Coeliac disease-associated risk variants in TNFAIP3 and REL implicate altered NF-κB signalling von Trynka, G, Zhernakova, A, Romanos, J, Franke, L, Hunt, K A, Turner, G, Bruinenberg, M, Heap, G A, Platteel, M, Ryan, A W, de Kovel, C, Holmes, G K T, Howdle, P D, Walters, J R F, Sanders, D S, Mulder, C J J, Mearin, M L, Verbeek, W H M, Trimble, V, Stevens, F M, Kelleher, D, Barisani, D, Bardella, M T, McManus, R, van Heel, D A, Wijmenga, C

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Relationship between chemical composition and in situ rumen degradation characteristics of maize silages in dairy cows von Ali, M., van Duinkerken, G., Cone, J. W., Klop, A., Blok, M. C., Spek, J. W., Bruinenberg, M. H., Hendriks, W. H.

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Sleep Disturbances in Phenylketonuria: An Explorative Study in Men and Mice von Bruinenberg, Vibeke M, Gordijn, Marijke C M, MacDonald, Anita, van Spronsen, Francjan J, Van der Zee, Eddy A

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A Specific Nutrient Combination Attenuates the Reduced Expression of PSD-95 in the Proximal Dendrites of Hippocampal Cell Body Layers in a Mouse Model of Phenylketonuria von Bruinenberg, Vibeke M, van Vliet, Danique, Attali, Amos, de Wilde, Martijn C, Kuhn, Mirjam, van Spronsen, Francjan J, van der Zee, Eddy A

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Pleiotropic effects of obesity-susceptibility loci on metabolic traits: a meta-analysis of up to 37,874 individuals von van Vliet-Ostaptchouk, J. V., den Hoed, M., Luan, J., Zhao, J. H., Ong, K. K., van der Most, P. J., Wong, A., Hardy, R., Kuh, D., van der Klauw, M. M., Bruinenberg, M., Khaw, K. T., Wolffenbuttel, B. H. R., Wareham, N. J., Snieder, H., Loos, R. J. F.

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SERPINE1 -675 4G/5G polymorphism is associated with asthma severity and inhaled corticosteroid response von DIJKSTRA, A, POSTMA, D. S, BRUINENBERG, M, VAN DIEMEN, C. C, BOEZEN, H. M, KOPPELMAN, G. H, TIMENS, W, VONK, J. M

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Investigation of novel salivary biomarkers in paediatric food allergy von Weger, Wouter W., Bruinenberg, Vibeke M., Gerrits, Jeroen H., Lente, Lidy, Herpertz, Catherina E. M., Meulen, Gerbrich N., Sprikkelman, Aline B., Koppelman, Gerard H., Kamps, Arvid W. A.

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Comparison of fractionation methods for nitrogen and starch in maize and grass silages von Ali, M., de Jonge, L. H., Cone, J. W., van Duinkerken, G., Blok, M. C., Bruinenberg, M. H., Hendriks, W. H.

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Postruminal degradation of crude protein, neutral detergent fibre and starch of maize and grass silages in dairy cows von Ali, M., Weisbjerg, M.R., Cone, J.W., van Duinkerken, G., Blok, M.C., Bruinenberg, M., Hendriks, W.H.

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Therapeutic brain modulation with targeted large neutral amino acid supplements in the Pah-enu2 phenylketonuria mouse model von van Vliet, Danique, Bruinenberg, Vibeke M, Mazzola, Priscila N, van Faassen, Martijn Hjr, de Blaauw, Pim, Pascucci, Tiziana, Puglisi-Allegra, Stefano, Kema, Ido P, Heiner-Fokkema, M Rebecca, van der Zee, Eddy A, van Spronsen, Francjan J

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Variation between individual cows in in situ rumen degradation characteristics of maize and grass silages von Ali, M., Cone, J.W., van Duinkerken, G., Klop, A., Blok, M.C., Bruinenberg, M., Khan, N.A., Hendriks, W.H.

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Gene expression analysis predicts insect venom anaphylaxis in indolent systemic mastocytosis von Niedoszytko, M., Bruinenberg, M., van Doormaal, J. J., de Monchy, J. G. R., Nedoszytko, B., Koppelman, G. H., Nawijn, M. C., Wijmenga, C., Jassem, E., Elberink, J. N. G. Oude

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Detection of Salivary Tryptase Levels in Children following Oral Food Challenges von de Weger, Wouter W., Bruinenberg, Vibeke M., van der Lek, Evelien M., Gerrits, Jeroen H., van Lente, Lidy, Herpertz, Catherina E.M., van der Meulen, Gerbrich N., Sprikkelman, Aline B., Koppelman, Gerard H., Kamps, Arvid W.A.

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Large neutral amino acid supplementation as an alternative to the phenylalanine-restricted diet in adults with phenylketonuria: evidence from adult Pah-enu2 mice von van Vliet, Danique, van der Goot, Els, Bruinenberg, Vibeke M., van Faassen, Martijn, de Blaauw, Pim, Kema, Ido P., Heiner-Fokkema, M. Rebecca, van der Zee, Eddy A., van Spronsen, Francjan J.

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Hippocampal microglia modifications in C57Bl/6 Pahenu2 and BTBR Pahenu2 phenylketonuria (PKU) mice depend on the genetic background, irrespective of disturbed sleep patterns von van der Goot, Els, Bruinenberg, Vibeke M., Hormann, Femke M., Eisel, Ulrich L.M., van Spronsen, Francjan J., Van der Zee, Eddy A.

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