Unbiased detection of CRISPR off-targets in vivo using DISCOVER-Seq von Wienert, Beeke, Wyman, Stacia K., Richardson, Christopher D., Yeh, Charles D., Akcakaya, Pinar, Porritt, Michelle J., Morlock, Michaela, Vu, Jonathan T., Kazane, Katelynn R., Watry, Hannah L., Judge, Luke M., Conklin, Bruce R., Maresca, Marcello, Corn, Jacob E.

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Generation of spatial-patterned early-developing cardiac organoids using human pluripotent stem cells von Hoang, Plansky, Wang, Jason, Conklin, Bruce R, Healy, Kevin E, Ma, Zhen

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Human iPSC-based Cardiac Microphysiological System For Drug Screening Applications von Mathur, Anurag, Loskill, Peter, Shao, Kaifeng, Huebsch, Nathaniel, Hong, SoonGweon, Marcus, Sivan G., Marks, Natalie, Mandegar, Mohammad, Conklin, Bruce R., Lee, Luke P., Healy, Kevin E.

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CRISPRi-based genome-scale identification of functional long noncoding RNA loci in human cells von Liu, S. John, Horlbeck, Max A., Cho, Seung Woo, Birk, Harjus S., Malatesta, Martina, He, Daniel, Attenello, Frank J., Villalta, Jacqueline E., Cho, Min Y., Chen, Yuwen, Mandegar, Mohammad A., Olvera, Michael P., Gilbert, Luke A., Conklin, Bruce R., Chang, Howard Y., Weissman, Jonathan S., Lim, Daniel A.

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Systematic quantification of HDR and NHEJ reveals effects of locus, nuclease, and cell type on genome-editing von Miyaoka, Yuichiro, Berman, Jennifer R., Cooper, Samantha B., Mayerl, Steven J., Chan, Amanda H., Zhang, Bin, Karlin-Neumann, George A., Conklin, Bruce R.

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Mapping cis-regulatory chromatin contacts in neural cells links neuropsychiatric disorder risk variants to target genes von Song, Michael, Yang, Xiaoyu, Ren, Xingjie, Maliskova, Lenka, Li, Bingkun, Jones, Ian R., Wang, Chao, Jacob, Fadi, Wu, Kenneth, Traglia, Michela, Tam, Tsz Wai, Jamieson, Kirsty, Lu, Si-Yao, Ming, Guo-Li, Li, Yun, Yao, Jun, Weiss, Lauren A., Dixon, Jesse R., Judge, Luke M., Conklin, Bruce R., Song, Hongjun, Gan, Li, Shen, Yin

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Isolation of single-base genome-edited human iPS cells without antibiotic selection von Miyaoka, Yuichiro, Chan, Amanda H, Judge, Luke M, Yoo, Jennie, Huang, Miller, Nguyen, Trieu D, Lizarraga, Paweena P, So, Po-Lin, Conklin, Bruce R

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WikiPathways: pathway editing for the people von Pico, Alexander R, Kelder, Thomas, van Iersel, Martijn P, Hanspers, Kristina, Conklin, Bruce R, Evelo, Chris

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GO-Elite: a flexible solution for pathway and ontology over-representation von ZAMBON, Alexander C, GAJ, Stan, HO, Isaac, HANSPERS, Kristina, VRANIZAN, Karen, EVELO, Chris T, CONKLIN, Bruce R, PICO, Alexander R, SALOMONIS, Nathan

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AltAnalyze and DomainGraph: analyzing and visualizing exon expression data von Emig, Dorothea, Salomonis, Nathan, Baumbach, Jan, Lengauer, Thomas, Conklin, Bruce R, Albrecht, Mario

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Timed inhibition of CDC7 increases CRISPR-Cas9 mediated templated repair von Wienert, Beeke, Nguyen, David N., Guenther, Alexis, Feng, Sharon J., Locke, Melissa N., Wyman, Stacia K., Shin, Jiyung, Kazane, Katelynn R., Gregory, Georgia L., Carter, Matthew A. M., Wright, Francis, Conklin, Bruce R., Marson, Alex, Richardson, Chris D., Corn, Jacob E.

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Ligand-binding domains of nuclear receptors facilitate tight control of split CRISPR activity von Nguyen, Duy P., Miyaoka, Yuichiro, Gilbert, Luke A., Mayerl, Steven J., Lee, Brian H., Weissman, Jonathan S., Conklin, Bruce R., Wells, James A.

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Multi-Imaging Method to Assay the Contractile Mechanical Output of Micropatterned Human iPSC-Derived Cardiac Myocytes von Ribeiro, Alexandre J.S, Schwab, Olivier, Mandegar, Mohammad A, Ang, Yen-Sin, Conklin, Bruce R, Srivastava, Deepak, Pruitt, Beth L

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Presenting and exploring biological pathways with PathVisio von van Iersel, Martijn P, Kelder, Thomas, Pico, Alexander R, Hanspers, Kristina, Coort, Susan, Conklin, Bruce R, Evelo, Chris

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Integration of biological networks and gene expression data using Cytoscape von Ideker, Trey, Cline, Melissa S, Smoot, Michael, Cerami, Ethan, Kuchinsky, Allan, Landys, Nerius, Workman, Chris, Christmas, Rowan, Avila-Campilo, Iliana, Creech, Michael, Gross, Benjamin, Hanspers, Kristina, Isserlin, Ruth, Kelley, Ryan, Killcoyne, Sarah, Lotia, Samad, Maere, Steven, Morris, John, Ono, Keiichiro, Pavlovic, Vuk, Pico, Alexander R, Vailaya, Aditya, Wang, Peng-Liang, Adler, Annette, Conklin, Bruce R, Hood, Leroy, Kuiper, Martin, Sander, Chris, Schmulevich, Ilya, Schwikowski, Benno, Warner, Guy J, Bader, Gary D

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BMP-SMAD-ID promotes reprogramming to pluripotency by inhibiting p16/INK4A-dependent senescence von Hayashi, Yohei, Hsiao, Edward C., Sami, Salma, Lancero, Mariselle, Schlieve, Christopher R., Nguyen, Trieu, Yano, Koyori, Nagahashi, Ayako, Ikeya, Makoto, Matsumoto, Yoshihisa, Nishimura, Ken, Fukuda, Aya, Hisatake, Koji, Tomoda, Kiichiro, Asaka, Isao, Toguchida, Junya, Conklin, Bruce R., Yamanaka, Shinya

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Synthetic control of mammalian-cell motility by engineering chemotaxis to an orthogonal bioinert chemical signal von Park, Jason S., Rhau, Benjamin, Hermann, Aynur, McNally, Krista A., Zhou, Carmen, Gong, Delquin, Weiner, Orion D., Conklin, Bruce R., Onuffer, James, Lim, Wendell A.

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A non-invasive platform for functional characterization of stem-cell-derived cardiomyocytes with applications in cardiotoxicity testing von Maddah, Mahnaz, Heidmann, Julia D, Mandegar, Mohammad A, Walker, Chase D, Bolouki, Sara, Conklin, Bruce R, Loewke, Kevin E

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The BridgeDb framework: standardized access to gene, protein and metabolite identifier mapping services von van Iersel, Martijn P, Pico, Alexander R, Kelder, Thomas, Gao, Jianjiong, Ho, Isaac, Hanspers, Kristina, Conklin, Bruce R, Evelo, Chris T

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Lentiviral vectors and protocols for creation of stable hESC lines for fluorescent tracking and drug resistance selection of cardiomyocytes von Kita-Matsuo, Hiroko, Barcova, Maria, Prigozhina, Natalie, Salomonis, Nathan, Wei, Karen, Jacot, Jeffrey G, Nelson, Brandon, Spiering, Sean, Haverslag, René, Kim, Changsung, Talantova, Maria, Bajpai, Ruchi, Calzolari, Diego, Terskikh, Alexey, McCulloch, Andrew D, Price, Jeffrey H, Conklin, Bruce R, Chen, H S Vincent, Mercola, Mark

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