Exploiting DNA Replication Stress for Cancer Treatment von Ubhi, Tajinder, Brown, Grant W

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Unification of Protein Abundance Datasets Yields a Quantitative Saccharomyces cerevisiae Proteome von Ho, Brandon, Baryshnikova, Anastasia, Brown, Grant W.

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A Genetic Map of the Response to DNA Damage in Human Cells von Olivieri, Michele, Cho, Tiffany, Álvarez-Quilón, Alejandro, Li, Kejiao, Schellenberg, Matthew J., Zimmermann, Michal, Hustedt, Nicole, Rossi, Silvia Emma, Adam, Salomé, Melo, Henrique, Heijink, Anne Margriet, Sastre-Moreno, Guillermo, Moatti, Nathalie, Szilard, Rachel K., McEwan, Andrea, Ling, Alexanda K., Serrano-Benitez, Almudena, Ubhi, Tajinder, Feng, Sumin, Pawling, Judy, Delgado-Sainz, Irene, Ferguson, Michael W., Dennis, James W., Brown, Grant W., Cortés-Ledesma, Felipe, Williams, R. Scott, Martin, Alberto, Xu, Dongyi, Durocher, Daniel

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P-body proteins regulate transcriptional rewiring to promote DNA replication stress resistance von Loll-Krippleber, Raphael, Brown, Grant W.

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The endonuclease Cue2 cleaves mRNAs at stalled ribosomes during No Go Decay von D'Orazio, Karole N, Wu, Colin Chih-Chien, Sinha, Niladri, Loll-Krippleber, Raphael, Brown, Grant W, Green, Rachel

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Systematic analysis of complex genetic interactions von Kuzmin, Elena, VanderSluis, Benjamin, Wang, Wen, Tan, Guihong, Deshpande, Raamesh, Chen, Yiqun, Usaj, Matej, Balint, Attila, Mattiazzi Usaj, Mojca, van Leeuwen, Jolanda, Koch, Elizabeth N, Pons, Carles, Dagilis, Andrius J, Pryszlak, Michael, Wang, Jason Zi Yang, Hanchard, Julia, Riggi, Margot, Xu, Kaicong, Heydari, Hamed, San Luis, Bryan-Joseph, Shuteriqi, Ermira, Zhu, Hongwei, Van Dyk, Nydia, Sharifpoor, Sara, Costanzo, Michael, Loewith, Robbie, Caudy, Amy, Bolnick, Daniel, Brown, Grant W, Andrews, Brenda J, Boone, Charles, Myers, Chad L

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CX-5461 is a DNA G-quadruplex stabilizer with selective lethality in BRCA1/2 deficient tumours von Xu, Hong, Di Antonio, Marco, McKinney, Steven, Mathew, Veena, Ho, Brandon, O’Neil, Nigel J., Santos, Nancy Dos, Silvester, Jennifer, Wei, Vivien, Garcia, Jessica, Kabeer, Farhia, Lai, Daniel, Soriano, Priscilla, Banáth, Judit, Chiu, Derek S., Yap, Damian, Le, Daniel D., Ye, Frank B., Zhang, Anni, Thu, Kelsie, Soong, John, Lin, Shu-chuan, Tsai, Angela Hsin Chin, Osako, Tomo, Algara, Teresa, Saunders, Darren N., Wong, Jason, Xian, Jian, Bally, Marcel B., Brenton, James D., Brown, Grant W., Shah, Sohrab P., Cescon, David, Mak, Tak W., Caldas, Carlos, Stirling, Peter C., Hieter, Phil, Balasubramanian, Shankar, Aparicio, Samuel

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Diversity of eukaryotic DNA replication origins revealed by genome-wide analysis of chromatin structure von Berbenetz, Nicolas M, Nislow, Corey, Brown, Grant W

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The Monoterpene Carvacrol Generates Endoplasmic Reticulum Stress in the Pathogenic Fungus Candida albicans von Chaillot, Julien, Tebbji, Faiza, Remmal, Adnane, Boone, Charlie, Brown, Grant W, Bellaoui, Mohammed, Sellam, Adnane

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HELB Is a Feedback Inhibitor of DNA End Resection von Tkáč, Ján, Xu, Guotai, Adhikary, Hemanta, Young, Jordan T.F., Gallo, David, Escribano-Díaz, Cristina, Krietsch, Jana, Orthwein, Alexandre, Munro, Meagan, Sol, Wendy, Al-Hakim, Abdallah, Lin, Zhen-Yuan, Jonkers, Jos, Borst, Piet, Brown, Grant W., Gingras, Anne-Claude, Rottenberg, Sven, Masson, Jean-Yves, Durocher, Daniel

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Smc5/6 Mediated Sumoylation of the Sgs1-Top3-Rmi1 Complex Promotes Removal of Recombination Intermediates von Bonner, Jacob N., Choi, Koyi, Xue, Xiaoyu, Torres, Nikko P., Szakal, Barnabas, Wei, Lei, Wan, Bingbing, Arter, Meret, Matos, Joao, Sung, Patrick, Brown, Grant W., Branzei, Dana, Zhao, Xiaolan

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Functional Targeting of DNA Damage to a Nuclear Pore-Associated SUMO-Dependent Ubiquitin Ligase von Nagai, Shigeki, Dubrana, Karine, Tsai-Pflugfelder, Monika, Davidson, Marta B, Roberts, Tania M, Brown, Grant W, Varela, Elisa, Hediger, Florence, Gasser, Susan M, Krogan, Nevan J

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The cytidine deaminase APOBEC3C has unique sequence and genome feature preferences von Brown, Grant W

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Quantitative analysis of fitness and genetic interactions in yeast on a genome scale von Andrews, Brenda, Boone, Charles, Myers, Chad L, Baryshnikova, Anastasia, Costanzo, Michael, Kim, Yungil, Ding, Huiming, Koh, Judice, Toufighi, Kiana, Youn, Ji-Young, Ou, Jiongwen, San Luis, Bryan-Joseph, Bandyopadhyay, Sunayan, Hibbs, Matthew, Hess, David, Gingras, Anne-Claude, Bader, Gary D, Troyanskaya, Olga G, Brown, Grant W

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Distinct elongation stalls during translation are linked with distinct pathways for mRNA degradation von Veltri, Anthony J, D'Orazio, Karole N, Lessen, Laura N, Loll-Krippleber, Raphael, Brown, Grant W, Green, Rachel

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Functional annotation of chemical libraries across diverse biological processes von Piotrowski, Jeff S, Li, Sheena C, Deshpande, Raamesh, Simpkins, Scott W, Nelson, Justin, Yashiroda, Yoko, Barber, Jacqueline M, Safizadeh, Hamid, Wilson, Erin, Okada, Hiroki, Gebre, Abraham A, Kubo, Karen, Torres, Nikko P, LeBlanc, Marissa A, Andrusiak, Kerry, Okamoto, Reika, Yoshimura, Mami, DeRango-Adem, Eva, van Leeuwen, Jolanda, Shirahige, Katsuhiko, Baryshnikova, Anastasia, Brown, Grant W, Hirano, Hiroyuki, Costanzo, Michael, Andrews, Brenda, Ohya, Yoshikazu, Osada, Hiroyuki, Yoshida, Minoru, Myers, Chad L, Boone, Charles

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A Role for USP7 in DNA Replication von Jagannathan, Madhav, Nguyen, Tin, Gallo, David, Luthra, Niharika, Brown, Grant W., Saridakis, Vivian, Frappier, Lori

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RNF8 ubiquitylation of XRN2 facilitates R-loop resolution and restrains genomic instability in BRCA1 mutant cells von Krishnan, Rehna, Lapierre, Mariah, Gautreau, Brandon, Nixon, Kevin C J, El Ghamrasni, Samah, Patel, Parasvi S, Hao, Jun, Yerlici, V Talya, Guturi, Kiran Kumar Naidu, St-Germain, Jonathan, Mateo, Francesca, Saad, Amine, Algouneh, Arash, Earnshaw, Rebecca, Shili, Duan, Seitova, Alma, Miller, Joshua, Khosraviani, Negin, Penn, Adam, Ho, Brandon, Sanchez, Otto, Hande, M Prakash, Masson, Jean-Yves, Brown, Grant W, Alaoui-Jamali, Moulay, Reynolds, John J, Arrowsmith, Cheryl, Raught, Brian, Pujana, Miguel A, Mekhail, Karim, Stewart, Grant S, Hakem, Anne, Hakem, Razqallah

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Functional dissection of protein complexes involved in yeast chromosome biology using a genetic interaction map von Collins, S.R, Miller, K.M, Maas, N.L, Roguev, A, Fillingham, J, Chu, C.S, Schuldiner, M, Gebbia, M, Recht, J, Shales, M

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RMI, a new OB-fold complex essential for Bloom syndrome protein to maintain genome stability von Xu, Dongyi, Guo, Rong, Sobeck, Alexandra, Bachrati, Csanad Z, Yang, Jay, Enomoto, Takemi, Brown, Grant W, Hoatlin, Maureen E, Hickson, Ian D, Wang, Weidong

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