Strategies to improve in vivo toxicology outcomes for basic candidate drug molecules von Luker, Tim, Alcaraz, Lilian, Chohan, Kamaldeep K., Blomberg, Niklas, Brown, Dearg S., Butlin, Roger J., Elebring, Thomas, Griffin, Andrew M., Guile, Simon, St-Gallay, Stephen, Swahn, Britt-Marie, Swallow, Steve, Waring, Michael J., Wenlock, Mark C., Leeson, Paul D.

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The discovery of N-cyclopropyl-4-methyl-3-[6-(4-methylpiperazin-1-yl)-4-oxoquinazolin-3(4H)-yl]benzamide (AZD6703), a clinical p38α MAP kinase inhibitor for the treatment of inflam... von Brown, Dearg S., Cumming, John G., Bethel, Paul, Finlayson, Jonathan, Gerhardt, Stefan, Nash, Ian, Pauptit, Richard A., Pike, Kurt G., Reid, Alan, Snelson, Wendy, Swallow, Steve, Thompson, Caroline

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Multi-Step Application of Immobilized Reagents and Scavengers: A Total Synthesis of Epothilone C von Storer, R. Ian, Takemoto, Toshiyasu, Jackson, Philip S., Brown, Dearg S., Baxendale, Ian R., Ley, Steven V.

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A novel series of p38 MAP kinase inhibitors for the potential treatment of rheumatoid arthritis von BROWN, Dearg S, BELFIELD, Andrew J, BROWN, George R, CAMPBELL, Douglas, FOUBISTER, Alan, MASTERS, David J, PIKE, Kurt G, SNELSON, Wendy L, WELLS, Stuart L

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New .kappa.-receptor agonists based upon a 2-[(alkylamino)methyl]piperidine nucleus von Scopes, David I. C, Hayes, Norman F, Bays, David E, Belton, David, Brain, John, Brown, Dearg S, Judd, Duncan B, McElroy, Andrew B, Meerholz, Clive A

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Use of 2-phenylsulphonyl cyclic ethers in the preparation of tetrahydropyran and tetrahydrofuran acetals and in some glycosidation reactions von Brown, Dearg S., Ley, Steven V., Vile, Sadie, Thompson, Mervyn

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The discovery of N-cyclopropyl-4-methyl-3-[6-(4-methylpiperazin-1-yl)-4-oxoquinazol i n-3(4H)-yl]benzamide (AZD6703), a clinical p38I- MAP kinase inhibitor for the treatment of inf... von Brown, Dearg S, Cumming, John G, Bethel, Paul, Finlayson, Jonathan, Gerhardt, Stefan, Nash, Ian, Pauptit, Richard A, Pike, Kurt G, Reid, Alan, Snelson, Wendy, Swallow, Steve, Thompson, Caroline

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Preparation of cyclic ether acetals from 2-benzenesulphonylderivatives: a new mild glycosidation procedure von Brown, Dearg S., Ley, Steven V., Vile, Sadie

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Synthetic studies on furanoheliangolides. Stereocontrolled construction of the oxygen-bridged tricyclic framework von Brown, Dearg S, Paquette, Leo A

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Direct substitution of 2-benzenesulphonyl cyclic ethers using organozinc reagents von Brown, Dearg S., Ley, Steven V.

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Direct Substitution of 2-Phenylsulphonylpyrrolidines, -piperidines, -tetrahydrofurans and -tetrahydropyrans by Alkyl Organometallic Reagents in Dichloromethane von Brown, Dearg S., Charreau, Philippe, Ley, Steven V.

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A SURVEY OF 6,9-EPOXYCYCLODECA[B]FURAN SESQUITERPENES von BROWN, DS, PAQUETTE, LA

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Synthesis, antinociceptive activity and opioid receptor profiles of substituted trans-3-(decahydro- and octahydro-4a-isoquinolinyl)phenols von Judd, Duncan B, Brown, Dearg S, Lloyd, Jane E, McElroy, Andrew B, Scopes, David I. C, Birch, Phillip J, Hayes, Ann G, Sheehan, Michael J

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Cover Picture: Multi-Step Application of Immobilized Reagents and Scavengers: A Total Synthesis of Epothilone C (Chem. Eur. J. 10/2004) von Storer, R. Ian, Takemoto, Toshiyasu, Jackson, Philip S., Brown, Dearg S., Baxendale, Ian R., Ley, Steven V.

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Cover Picture: Multi-Step Application of Immobilized Reagents and Scavengers: A Total Synthesis of Epothilone C (Chem. Eur. J. 10/2004) von Storer, R. Ian, Takemoto, Toshiyasu, Jackson, Philip S., Brown, Dearg S., Baxendale, Ian R., Ley, Steven V.

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High Loading Polymer-Supported N-Methylmorpholine N-Oxide; A Practically Efficient and Readily Recyclable Promoter of the Pauson-Khand Reaction von Brown, Dearg S., Campbell, Elaine, Kerr, William J., Lindsay, David M., Morrison, Angus J., Pike, Kurt G., Watson, Stephen P.

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Substitution reactions of 2-phenylsulphonyl-piperidines and -pyrrolidines with carbon nucleophiles: Synthesis of the pyrrolidine alkaloids norruspoline and ruspolinone von Brown, Dearg S., Charreau, Philippe, Hansson, Thomas, Ley, Steven V.

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Merrifield, Alpha-MethoxyPhenyl (MAMP) resin; a new versatile solid support for the synthesis of secondary amides von Brown, Dearg S., Revill, John M., Shute, Richard E.

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Polymer-Supported N-Methylmorpholine N-Oxide as an Efficient and Readily Recyclable Co-oxidant in the TPAP Oxidation of Alcohols von Brown, Dearg S., Kerr, William J., Lindsay, David M., Pike, Kurt G., Ratcliffe, Paul D.

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Substitution reactions of 2-benzenesulphonyl cyclic ethers with carbon nucleophiles von Brown, Dearg S., Bruno, Maurizio, Davenport, Raymond J., Ley, Steven V.

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