Transposable elements generate regulatory novelty in a tissue-specific fashion von Trizzino, Marco, Kapusta, Aurélie, Brown, Christopher D

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Transposable elements are the primary source of novelty in primate gene regulation von Trizzino, Marco, Park, YoSon, Holsbach-Beltrame, Marcia, Aracena, Katherine, Mika, Katelyn, Caliskan, Minal, Perry, George H, Lynch, Vincent J, Brown, Christopher D

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Exploiting the GTEx resources to decipher the mechanisms at GWAS loci von Barbeira, Alvaro N., Bonazzola, Rodrigo, Gamazon, Eric R., Liang, Yanyu, Park, YoSon, Kim-Hellmuth, Sarah, Wang, Gao, Jiang, Zhuoxun, Zhou, Dan, Hormozdiari, Farhad, Liu, Boxiang, Rao, Abhiram, Hamel, Andrew R., Pividori, Milton D., Aguet, Francois, Bastarache, Lisa, Jordan, Daniel M., Verbanck, Marie, Do, Ron, Stephens, Matthew, Ardlie, Kristin, McCarthy, Mark, Montgomery, Stephen B., Segre, Ayellet V., Brown, Christopher D., Lappalainen, Tuuli, Wen, Xiaoquan, Im, Hae Kyung

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Integrative modeling of eQTLs and cis-regulatory elements suggests mechanisms underlying cell type specificity of eQTLs von Brown, Christopher D, Mangravite, Lara M, Engelhardt, Barbara E

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Loss of Function of GALNT2 Lowers High-Density Lipoproteins in Humans, Nonhuman Primates, and Rodents von Khetarpal, Sumeet A., Schjoldager, Katrine T., Christoffersen, Christina, Raghavan, Avanthi, Edmondson, Andrew C., Reutter, Heiko M., Ahmed, Bouhouche, Ouazzani, Reda, Peloso, Gina M., Vitali, Cecilia, Zhao, Wei, Somasundara, Amritha Varshini Hanasoge, Millar, John S., Park, YoSon, Fernando, Gayani, Livanov, Valentin, Choi, Seungbum, Noé, Eric, Patel, Pritesh, Ho, Siew Peng, Kirchgessner, Todd G., Wandall, Hans H., Hansen, Lars, Bennett, Eric P., Vakhrushev, Sergey Y., Saleheen, Danish, Kathiresan, Sekar, Brown, Christopher D., Abou Jamra, Rami, LeGuern, Eric, Clausen, Henrik, Rader, Daniel J.

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Mapping the genetic architecture of human traits to cell types in the kidney identifies mechanisms of disease and potential treatments von Sheng, Xin, Guan, Yuting, Ma, Ziyuan, Wu, Junnan, Liu, Hongbo, Qiu, Chengxiang, Vitale, Steven, Miao, Zhen, Seasock, Matthew J., Palmer, Matthew, Shin, Myung K., Duffin, Kevin L., Pullen, Steven S., Edwards, Todd L., Hellwege, Jacklyn N., Hung, Adriana M., Li, Mingyao, Voight, Benjamin F., Coffman, Thomas M., Brown, Christopher D., Susztak, Katalin

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Integrative analysis of head and neck cancer identifies two biologically distinct HPV and three non-HPV subtypes von Keck, Michaela K, Zuo, Zhixiang, Khattri, Arun, Stricker, Thomas P, Brown, Christopher D, Imanguli, Matin, Rieke, Damian, Endhardt, Katharina, Fang, Petra, Brägelmann, Johannes, DeBoer, Rebecca, El-Dinali, Mohamed, Aktolga, Serdal, Lei, Zhengdeng, Tan, Patrick, Rozen, Steve G, Salgia, Ravi, Weichselbaum, Ralph R, Lingen, Mark W, Story, Michael D, Ang, K Kian, Cohen, Ezra E W, White, Kevin P, Vokes, Everett E, Seiwert, Tanguy Y

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A comprehensive map of insulator elements for the Drosophila genome von Nègre, Nicolas, Brown, Christopher D, Shah, Parantu K, Kheradpour, Pouya, Morrison, Carolyn A, Henikoff, Jorja G, Feng, Xin, Ahmad, Kami, Russell, Steven, White, Robert A H, Stein, Lincoln, Henikoff, Steven, Kellis, Manolis, White, Kevin P

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A Dementia-Associated Risk Variant near TMEM106B Alters Chromatin Architecture and Gene Expression von Gallagher, Michael D., Posavi, Marijan, Huang, Peng, Unger, Travis L., Berlyand, Yosef, Gruenewald, Analise L., Chesi, Alessandra, Manduchi, Elisabetta, Wells, Andrew D., Grant, Struan F.A., Blobel, Gerd A., Brown, Christopher D., Chen-Plotkin, Alice S.

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Large, Diverse Population Cohorts of hiPSCs and Derived Hepatocyte-like Cells Reveal Functional Genetic Variation at Blood Lipid-Associated Loci von Pashos, Evanthia E., Park, YoSon, Wang, Xiao, Raghavan, Avanthi, Yang, Wenli, Abbey, Deepti, Peters, Derek T., Arbelaez, Juan, Hernandez, Mayda, Kuperwasser, Nicolas, Li, Wenjun, Lian, Zhaorui, Liu, Ying, Lv, Wenjian, Lytle-Gabbin, Stacey L., Marchadier, Dawn H., Rogov, Peter, Shi, Jianting, Slovik, Katherine J., Stylianou, Ioannis M., Wang, Li, Yan, Ruilan, Zhang, Xiaolan, Kathiresan, Sekar, Duncan, Stephen A., Mikkelsen, Tarjei S., Morrisey, Edward E., Rader, Daniel J., Brown, Christopher D., Musunuru, Kiran

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Robust stratification of breast cancer subtypes using differential patterns of transcript isoform expression von Stricker, Thomas P, Brown, Christopher D, Bandlamudi, Chaitanya, McNerney, Megan, Kittler, Ralf, Montoya, Vanessa, Peterson, April, Grossman, Robert, White, Kevin P

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Context Specific and Differential Gene Co-expression Networks via Bayesian Biclustering von Gao, Chuan, McDowell, Ian C, Zhao, Shiwen, Brown, Christopher D, Engelhardt, Barbara E

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Impact of admixture and ancestry on eQTL analysis and GWAS colocalization in GTEx von Gay, Nicole R., Gloudemans, Michael, Antonio, Margaret L., Abell, Nathan S., Balliu, Brunilda, Park, YoSon, Martin, Alicia R., Musharoff, Shaila, Rao, Abhiram S., Aguet, Francois, Barbeira, Alvaro N., Bonazzola, Rodrigo, Hormozdiari, Farhad, Ardlie, Kristin G., Brown, Christopher D., Im, Hae Kyung, Lappalainen, Tuuli, Wen, Xiaoquan, Montgomery, Stephen B.

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Receiver operating characteristics curves and related decision measures: A tutorial von Brown, Christopher D., Davis, Herbert T.

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Genomic profiling of human vascular cells identifies TWIST1 as a causal gene for common vascular diseases von Nurnberg, Sylvia T., Guerraty, Marie A., Wirka, Robert C., Rao, H. Shanker, Pjanic, Milos, Norton, Scott, Serrano, Felipe, Perisic, Ljubica, Elwyn, Susannah, Pluta, John, Zhao, Wei, Testa, Stephanie, Park, YoSon, Nguyen, Trieu, Ko, Yi-An, Wang, Ting, Hedin, Ulf, Sinha, Sanjay, Barash, Yoseph, Brown, Christopher D., Quertermous, Thomas, Rader, Daniel J.

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Chromatin occupancy analysis reveals genome-wide GATA factor switching during hematopoiesis von Doré, Louis C., Chlon, Timothy M., Brown, Christopher D., White, Kevin P., Crispino, John D.

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CUX1 is a haploinsufficient tumor suppressor gene on chromosome 7 frequently inactivated in acute myeloid leukemia von McNerney, Megan E., Brown, Christopher D., Wang, Xiaoyue, Bartom, Elizabeth T., Karmakar, Subhradip, Bandlamudi, Chaitanya, Yu, Shan, Ko, Jinkyung, Sandall, Barry P., Stricker, Thomas, Anastasi, John, Grossman, Robert L., Cunningham, John M., Le Beau, Michelle M., White, Kevin P.

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sn-spMF: matrix factorization informs tissue-specific genetic regulation of gene expression von He, Yuan, Chhetri, Surya B., Arvanitis, Marios, Srinivasan, Kaushik, Aguet, Francois, Ardlie, Kristin G., Barbeira, Alvaro N., Bonazzola, Rodrigo, Im, Hae Kyung, Brown, Christopher D., Battle, Alexis

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The genetic and evolutionary basis of gene expression variation in East Africans von Kelly, Derek E, Ramdas, Shweta, Ma, Rong, Rawlings-Goss, Renata A, Grant, Gregory R, Ranciaro, Alessia, Hirbo, Jibril B, Beggs, William, Yeager, Meredith, Chanock, Stephen, Nyambo, Thomas B, Omar, Sabah A, Woldemeskel, Dawit, Belay, Gurja, Li, Hongzhe, Brown, Christopher D, Tishkoff, Sarah A

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Genetic and Epigenetic Fine Mapping of Complex Trait Associated Loci in the Human Liver von Çalışkan, Minal, Manduchi, Elisabetta, Rao, H. Shanker, Segert, Julian A., Beltrame, Marcia Holsbach, Trizzino, Marco, Park, YoSon, Baker, Samuel W., Chesi, Alessandra, Johnson, Matthew E., Hodge, Kenyaita M., Leonard, Michelle E., Loza, Baoli, Xin, Dong, Berrido, Andrea M., Hand, Nicholas J., Bauer, Robert C., Wells, Andrew D., Olthoff, Kim M., Shaked, Abraham, Rader, Daniel J., Grant, Struan F.A., Brown, Christopher D.

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