Activins and Inhibins: Roles in Development, Physiology, and Disease von Namwanje, Maria, Brown, Chester W

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Macrophage PPARγ, a Lipid Activated Transcription Factor Controls the Growth Factor GDF3 and Skeletal Muscle Regeneration von Varga, Tamas, Mounier, Rémi, Patsalos, Andreas, Gogolák, Péter, Peloquin, Matthew, Horvath, Attila, Pap, Attila, Daniel, Bence, Nagy, Gergely, Pintye, Eva, Poliska, Szilárd, Cuvellier, Sylvain, Ben Larbi, Sabrina, Sansbury, Brian E., Spite, Matthew, Brown, Chester W., Chazaud, Bénédicte, Nagy, Laszlo

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Insulin Regulates Lipolysis and Fat Mass by Upregulating Growth/Differentiation Factor 3 in Adipose Tissue Macrophages von Bu, Yun, Okunishi, Katsuhide, Yogosawa, Satomi, Mizuno, Kouichi, Irudayam, Maria Johnson, Brown, Chester W, Izumi, Tetsuro

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Complex Compound Inheritance of Lethal Lung Developmental Disorders Due to Disruption of the TBX-FGF Pathway von Karolak, Justyna A., Vincent, Marie, Deutsch, Gail, Gambin, Tomasz, Cogné, Benjamin, Pichon, Olivier, Vetrini, Francesco, Mefford, Heather C., Dines, Jennifer N., Golden-Grant, Katie, Dipple, Katrina, Freed, Amanda S., Leppig, Kathleen A., Dishop, Megan, Mowat, David, Bennetts, Bruce, Gifford, Andrew J., Weber, Martin A., Lee, Anna F., Boerkoel, Cornelius F., Bartell, Tina M., Ward-Melver, Catherine, Besnard, Thomas, Petit, Florence, Bache, Iben, Tümer, Zeynep, Denis-Musquer, Marie, Joubert, Madeleine, Martinovic, Jelena, Bénéteau, Claire, Molin, Arnaud, Carles, Dominique, André, Gwenaelle, Bieth, Eric, Chassaing, Nicolas, Devisme, Louise, Chalabreysse, Lara, Pasquier, Laurent, Secq, Véronique, Don, Massimiliano, Orsaria, Maria, Missirian, Chantal, Mortreux, Jérémie, Sanlaville, Damien, Pons, Linda, Küry, Sébastien, Bézieau, Stéphane, Liet, Jean-Michel, Joram, Nicolas, Bihouée, Tiphaine, Scott, Daryl A., Brown, Chester W., Scaglia, Fernando, Tsai, Anne Chun-Hui, Grange, Dorothy K., Phillips, John A., Pfotenhauer, Jean P., Jhangiani, Shalini N., Gonzaga-Jauregui, Claudia G., Chung, Wendy K., Schauer, Galen M., Lipson, Mark H., Mercer, Catherine L., van Haeringen, Arie, Liu, Qian, Popek, Edwina, Coban Akdemir, Zeynep H., Lupski, James R., Szafranski, Przemyslaw, Isidor, Bertrand, Le Caignec, Cedric, Stankiewicz, Paweł

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Haploinsufficiency of the Chromatin Remodeler BPTF Causes Syndromic Developmental and Speech Delay, Postnatal Microcephaly, and Dysmorphic Features von Stankiewicz, Paweł, Khan, Tahir N., Szafranski, Przemyslaw, Slattery, Leah, Streff, Haley, Vetrini, Francesco, Bernstein, Jonathan A., Brown, Chester W., Rosenfeld, Jill A., Rednam, Surya, Scollon, Sarah, Bergstrom, Katie L., Parsons, Donald W., Plon, Sharon E., Vieira, Marta W., Quaio, Caio R.D.C., Baratela, Wagner A.R., Acosta Guio, Johanna C., Armstrong, Ruth, Mehta, Sarju G., Rump, Patrick, Pfundt, Rolph, Lewandowski, Raymond, Fernandes, Erica M., Shinde, Deepali N., Tang, Sha, Hoyer, Juliane, Zweier, Christiane, Reis, André, Bacino, Carlos A., Xiao, Rui, Breman, Amy M., Smith, Janice L., Katsanis, Nicholas, Bostwick, Bret, Popp, Bernt, Davis, Erica E., Yang, Yaping

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Spatially clustering de novo variants in CYFIP2, encoding the cytoplasmic FMRP interacting protein 2, cause intellectual disability and seizures von Zweier, Markus, Begemann, Anaïs, McWalter, Kirsty, Cho, Megan T, Abela, Lucia, Banka, Siddharth, Behring, Bettina, Berger, Andrea, Brown, Chester W, Carneiro, Maryline, Chen, Jiani, Cooper, Gregory M, Finnila, Candice R, Guillen Sacoto, Maria J, Henderson, Alex, Hüffmeier, Ulrike, Joset, Pascal, Kerr, Bronwyn, Lesca, Gaetan, Leszinski, Gloria S, McDermott, John Henry, Meltzer, Meira R, Monaghan, Kristin G, Mostafavi, Roya, Õunap, Katrin, Plecko, Barbara, Powis, Zöe, Purcarin, Gabriela, Reimand, Tiia, Riedhammer, Korbinian M, Schreiber, John M, Sirsi, Deepa, Wierenga, Klaas J, Wojcik, Monica H, Papuc, Sorina M, Steindl, Katharina, Sticht, Heinrich, Rauch, Anita

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Absence of Heterozygosity Due to Template Switching during Replicative Rearrangements von Carvalho, Claudia M.B., Pfundt, Rolph, King, Daniel A., Lindsay, Sarah J., Zuccherato, Luciana W., Macville, Merryn V.E., Liu, Pengfei, Johnson, Diana, Stankiewicz, Pawel, Brown, Chester W., Shaw, Chad A., Hurles, Matthew E., Ira, Grzegorz, Hastings, P.J., Brunner, Han G., Lupski, James R.

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Phenotypic expansion of POGZ‐related intellectual disability syndrome (White‐Sutton syndrome) von Assia Batzir, Nurit, Posey, Jennifer E., Song, Xiaofei, Akdemir, Zeynep Coban, Rosenfeld, Jill A., Brown, Chester W., Chen, Emily, Holtrop, Shannon G., Mizerik, Elizabeth, Nieto Moreno, Margarita, Payne, Katelyn, Raas‐Rothschild, Annick, Scott, Richard, Vernon, Hilary J., Zadeh, Neda, Lupski, James R., Sutton, V. Reid

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Mutations in PURA Cause Profound Neonatal Hypotonia, Seizures, and Encephalopathy in 5q31.3 Microdeletion Syndrome von Lalani, Seema R., Zhang, Jing, Schaaf, Christian P., Brown, Chester W., Magoulas, Pilar, Tsai, Anne Chun-Hui, El-Gharbawy, Areeg, Wierenga, Klaas J., Bartholomew, Dennis, Fong, Chin-To, Barbaro-Dieber, Tina, Kukolich, Mary K., Burrage, Lindsay C., Austin, Elise, Keller, Kory, Pastore, Matthew, Fernandez, Fabio, Lotze, Timothy, Wilfong, Angus, Purcarin, Gabriela, Zhu, Wenmiao, Craigen, William J., McGuire, Marianne, Jain, Mahim, Cooney, Erin, Azamian, Mahshid, Bainbridge, Matthew N., Muzny, Donna M., Boerwinkle, Eric, Person, Richard E., Niu, Zhiyv, Eng, Christine M., Lupski, James R., Gibbs, Richard A., Beaudet, Arthur L., Yang, Yaping, Wang, Meng C., Xia, Fan

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Emerging Roles for the Transforming Growth Factor-β Superfamily in Regulating Adiposity and Energy Expenditure von Zamani, Nader, Brown, Chester W

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Dosage Changes of a Segment at 17p13.1 Lead to Intellectual Disability and Microcephaly as a Result of Complex Genetic Interaction of Multiple Genes von Carvalho, Claudia M.B., Vasanth, Shivakumar, Shinawi, Marwan, Russell, Chad, Ramocki, Melissa B., Brown, Chester W., Graakjaer, Jesper, Skytte, Anne-Bine, Vianna-Morgante, Angela M., Krepischi, Ana C.V., Patel, Gayle S., Immken, LaDonna, Aleck, Kyrieckos, Lim, Cynthia, Cheung, Sau Wai, Rosenberg, Carla, Katsanis, Nicholas, Lupski, James R.

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Mutations in LTBP4 Cause a Syndrome of Impaired Pulmonary, Gastrointestinal, Genitourinary, Musculoskeletal, and Dermal Development von Urban, Zsolt, Hucthagowder, Vishwanathan, Schürmann, Nura, Todorovic, Vesna, Zilberberg, Lior, Choi, Jiwon, Sens, Carla, Brown, Chester W., Clark, Robin D., Holland, Kristen E., Marble, Michael, Sakai, Lynn Y., Dabovic, Branka, Rifkin, Daniel B., Davis, Elaine C.

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Phenotypic spectrum and genotype―phenotype correlations of NRXN1 exon deletions von SCHAAF, Christian P, BOONE, Philip M, TARTAGLIA, Nicole R, EVANS, Patricia, CAMPBELL, William M, TSAI, Anne Chun-Hui, PARSLEY, Lea, GRAYSON, Stephanie W, SCHEUERLE, Angela, LUZZI, Carol D, THOMAS, Sandra K, ENG, Patricia A, SAMPATH, Srirangan, KANG, Sung-Hae L, PATEL, Ankita, STANKIEWICZ, Pawel, CHEUNG, Sau W, WILLIAMS, Charles, BADER, Patricia I, MUELLER, Jennifer M, SHCHELOCHKOV, Oleg A, BROWN, Chester W, CRAWFORD, Heather P, PHALEN, James A

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Case Report: An Infant With Kabuki Syndrome, Alobar Holoprosencephaly and Truncus Arteriosus: A Case for Whole Exome Sequencing in Neonates With Congenital Anomalies von Sakaria, Rishika P., Zaveri, Parul G., Holtrop, Shannon, Zhang, Jie, Brown, Chester W., Pivnick, Eniko K.

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Intraovarian Activins Are Required for Female Fertility von Pangas, Stephanie A, Jorgez, Carolina J, Tran, Mai, Agno, Julio, Li, Xiaohui, Brown, Chester W, Kumar, T. Rajendra, Matzuk, Martin M

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Inflammasome-driven catecholamine catabolism in macrophages blunts lipolysis during ageing von Camell, Christina D., Sander, Jil, Spadaro, Olga, Lee, Aileen, Nguyen, Kim Y., Wing, Allison, Goldberg, Emily L., Youm, Yun-Hee, Brown, Chester W., Elsworth, John, Rodeheffer, Matthew S., Schultze, Joachim L., Dixit, Vishwa Deep

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Exome Sequencing Reveals a Putative Role for HLA-C03:02 in Control of HIV-1 in African Pediatric Populations von Kyobe, Samuel, Mwesigwa, Savannah, Kisitu, Grace P., Farirai, John, Katagirya, Eric, Mirembe, Angella N., Ketumile, Lesego, Wayengera, Misaki, Katabazi, Fred Ashaba, Kigozi, Edgar, Wampande, Edward M., Retshabile, Gaone, Mlotshwa, Busisiwe C., Williams, Lesedi, Morapedi, Koketso, Kasvosve, Ishmael, Kyosiimire-Lugemwa, Jacqueline, Nsangi, Betty, Tsimako-Johnstone, Masego, Brown, Chester W., Joloba, Moses, Anabwani, Gabriel, Bhekumusa, Lukhele, Mpoloka, Sununguko W., Mardon, Graeme, Matshaba, Mogomotsi, Kekitiinwa, Adeodata, Hanchard, Neil A.

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Mitochondrial dysfunction in obesity von Bournat, Juan C, Brown, Chester W

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The Vg1-related protein Gdf3 acts in a Nodal signaling pathway in the pre-gastrulation mouse embryo von Chen, Canhe, Ware, Stephanie M, Sato, Akira, Houston-Hawkins, Dianne E, Habas, Raymond, Matzuk, Martin M, Shen, Michael M, Brown, Chester W

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Deficiency of Growth Differentiation Factor 3 Protects against Diet-Induced Obesity by Selectively Acting on White Adipose von Shen, Joseph J, Huang, Lihua, Li, Liunan, Jorgez, Carolina, Matzuk, Martin M, Brown, Chester W

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