Cohesin and CTCF differentially affect chromatin architecture and gene expression in human cells von Zuin, Jessica, Dixon, Jesse R., van der Reijden, Michael I. J. A., Ye, Zhen, Kolovos, Petros, Brouwer, Rutger W. W., van de Corput, Mariëtte P. C., van de Werken, Harmen J. G., Knoch, Tobias A., van IJcken, Wilfred F. J., Grosveld, Frank G., Ren, Bing, Wendt, Kerstin S.

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In vitro capture and characterization of embryonic rosette-stage pluripotency between naive and primed states von Neagu, Alex, van Genderen, Emiel, Escudero, Irene, Verwegen, Lucas, Kurek, Dorota, Lehmann, Johannes, Stel, Jente, Dirks, René A. M., van Mierlo, Guido, Maas, Alex, Eleveld, Cindy, Ge, Yang, den Dekker, Alexander. T., Brouwer, Rutger W. W., van IJcken, Wilfred F. J., Modic, Miha, Drukker, Micha, Jansen, Joop H., Rivron, Nicolas C., Baart, Esther B., Marks, Hendrik, ten Berge, Derk

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Epigenomic analysis of KLF1 haploinsufficiency in primary human erythroblasts von Heshusius, Steven, Grech, Laura, Gillemans, Nynke, Brouwer, Rutger W. W., den Dekker, Xander T., van IJcken, Wilfred F. J., Nota, Benjamin, Felice, Alex E., van Dijk, Thamar B., von Lindern, Marieke, Borg, Joseph, van den Akker, Emile, Philipsen, Sjaak

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Identification of candidate enhancers controlling the transcriptome during the formation of interphalangeal joints von Nowosad, Karol, Brouwer, Rutger W. W., Odrzywolski, Adrian, Korporaal, Anne L., Gielniewski, Bartłomiej, Wojtaś, Bartosz, van IJcken, Wilfred F. J., Grosveld, Frank, Huylebroeck, Danny, Tylzanowski, Przemko

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BMP4 and Temozolomide Synergize in the Majority of Patient-Derived Glioblastoma Cultures von Verploegh, Iris S C, Conidi, Andrea, El Hassnaoui, Hoesna, Verhoeven, Floor A M, Korporaal, Anne L, Ntafoulis, Ioannis, van den Hout, Mirjam C G N, Brouwer, Rutger W W, Lamfers, Martine L M, van IJcken, Wilfred F J, Huylebroeck, Danny, Leenstra, Sieger

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Clinical significance of immunohistochemistry for detection of BAP1 mutations in uveal melanoma von Koopmans, Anna E, Verdijk, Robert M, Brouwer, Rutger W W, van den Bosch, Thierry P P, van den Berg, Mike M P, Vaarwater, Jolanda, Kockx, Christel E M, Paridaens, Dion, Naus, Nicole C, Nellist, Mark, van IJcken, Wilfred F J, Kiliç, Emine, de Klein, Annelies

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The tumor suppressor MIR139 is silenced by POLR2M to promote AML oncogenesis von Stavast, Christiaan J., van Zuijen, Iris, Karkoulia, Elena, Özçelik, Arman, van Hoven-Beijen, Antoinette, Leon, Leticia G., Voerman, Jane S. A., Janssen, George M. C., van Veelen, Peter A., Burocziova, Monika, Brouwer, Rutger W. W., van IJcken, Wilfred F. J., Maas, Alex, Bindels, Eric M., van der Velden, Vincent H. J., Schliehe, Christopher, Katsikis, Peter D., Alberich-Jorda, Meritxell, Erkeland, Stefan J.

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Loss of LMOD1 impairs smooth muscle cytocontractility and causes megacystis microcolon intestinal hypoperistalsis syndrome in humans and mice von Halim, Danny, Wilson, Michael P., Oliver, Daniel, Brosens, Erwin, Verheij, Joke B. G. M., Han, Yu, Nanda, Vivek, Lyu, Qing, Doukas, Michael, Stoop, Hans, Brouwer, Rutger W. W., van IJcken, Wilfred F. J., Slivano, Orazio J., Burns, Alan J., Christie, Christine K., de Mesy Bentley, Karen L., Brooks, Alice S., Tibboel, Dick, Xu, Suowen, Jin, Zheng Gen, Djuwantono, Tono, Yan, Wei, Alves, Maria M., Hofstra, Robert M. W., Miano, Joseph M.

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CFTR Correctors and Antioxidants Partially Normalize Lipid Imbalance but not Abnormal Basal Inflammatory Cytokine Profile in CF Bronchial Epithelial Cells von Veltman, Mieke, De Sanctis, Juan B, Stolarczyk, Marta, Klymiuk, Nikolai, Bähr, Andrea, Brouwer, Rutger W, Oole, Edwin, Shah, Juhi, Ozdian, Tomas, Liao, Jie, Martini, Carolina, Radzioch, Danuta, Hanrahan, John W, Scholte, Bob J

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NOXA expression drives synthetic lethality to RUNX1 inhibition in pancreatic cancer von Doffo, Josefina, Bamopoulos, Stefanos A, Köse, Hazal, Orben, Felix, Zang, Chuanbing, Pons, Miriam, den Dekker, Alexander T, Brouwer, Rutger W W, Baluapuri, Apoorva, Habringer, Stefan, Reichert, Maximillian, Illendula, Anuradha, Krämer, Oliver H, Schick, Markus, Wolf, Elmar, van IJcken, Wilfred F J, Esposito, Irene, Keller, Ulrich, Schneider, Günter, Wirth, Matthias

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Single-Cell RNA Sequencing of Donor-Reactive T Cells Reveals Role of Apoptosis in Donor-Specific Hyporesponsiveness of Kidney Transplant Recipients von van der List, Amy C. J., Litjens, Nicolle H. R., Brouwer, Rutger W. W., Klepper, Mariska, den Dekker, Alexander T., van Ijcken, Wilfred F. J., Betjes, Michiel G. H.

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Targeted Next Generation Sequencing reveals previously unidentified TSC1 and TSC2 mutations von Nellist, Mark, Brouwer, Rutger W W, Kockx, Christel E M, van Veghel-Plandsoen, Monique, Withagen-Hermans, Caroline, Prins-Bakker, Lida, Hoogeveen-Westerveld, Marianne, Mrsic, Alan, van den Berg, Mike M P, Koopmans, Anna E, de Wit, Marie-Claire, Jansen, Floor E, Maat-Kievit, Anneke J A, van den Ouweland, Ans, Halley, Dicky, de Klein, Annelies, van IJcken, Wilfred F J

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PTRHD1 Loss‐of‐function mutation in an african family with juvenile‐onset Parkinsonism and intellectual disability von Kuipers, Demy J.S., Carr, Jonathan, Bardien, Soraya, Thomas, Pearl, Sebate, Boiketlo, Breedveld, Guido J., van Minkelen, Rick, Brouwer, Rutger W.W., van Ijcken, Wilfred F.J., van Slegtenhorst, Marjon A., Bonifati, Vincenzo, Quadri, Marialuisa

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Zeb2 DNA-Binding Sites in Neuroprogenitor Cells Reveal Autoregulation and Affirm Neurodevelopmental Defects, Including in Mowat-Wilson Syndrome von Birkhoff, Judith C, Korporaal, Anne L, Brouwer, Rutger W W, Nowosad, Karol, Milazzo, Claudia, Mouratidou, Lidia, van den Hout, Mirjam C G N, van IJcken, Wilfred F J, Huylebroeck, Danny, Conidi, Andrea

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The relative value of operon predictions von Brouwer, Rutger W. W., Kuipers, Oscar P., van Hijum, Sacha A. F. T.

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The detailed 3D multi-loop aggregate/rosette chromatin architecture and functional dynamic organization of the human and mouse genomes von Knoch, Tobias A, Wachsmuth, Malte, Kepper, Nick, Lesnussa, Michael, Abuseiris, Anis, Ali Imam, A M, Kolovos, Petros, Zuin, Jessica, Kockx, Christel E M, Brouwer, Rutger W W, van de Werken, Harmen J G, van IJcken, Wilfred F J, Wendt, Kerstin S, Grosveld, Frank G

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CRISPRs in the human genome are differentially expressed between malignant and normal adjacent to tumor tissue von van Riet, Job, Saha, Chinmoy, Strepis, Nikolaos, Brouwer, Rutger W. W., Martens-Uzunova, Elena S., van de Geer, Wesley S., Swagemakers, Sigrid M. A., Stubbs, Andrew, Halimi, Yassir, Voogd, Sanne, Tanmoy, Arif Mohammad, Komor, Malgorzata A., Hoogstrate, Youri, Janssen, Bart, Fijneman, Remond J. A., Niknafs, Yashar S., Chinnaiyan, Arul M., van IJcken, Wilfred F. J., van der Spek, Peter J., Jenster, Guido, Louwen, Rogier

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Effect of bovine milk fat-based infant formulae on microbiota, metabolites and stool parameters in healthy term infants in a randomized, crossover, placebo-controlled trial von Looijesteijn, Ellen, Brouwer, Rutger W. W., Schoemaker, Ruud J. W., Ulfman, Laurien H., Ham, Stephanie L., Jeurink, Prescilla, Karaglani, Eva, van IJcken, Wilfred F. J., Manios, Yannis

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Validation of a Combined Transcriptome and T Cell Receptor Alpha/Beta (TRA/TRB) Repertoire Assay at the Single Cell Level for Paucicellular Samples von Litjens, Nicolle H R, Langerak, Anton W, van der List, Amy C J, Klepper, Mariska, de Bie, Maaike, Azmani, Zakia, den Dekker, Alexander T, Brouwer, Rutger W W, Betjes, Michiel G H, Van IJcken, Wilfred F J

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Unraveling the Genetics of Congenital Diaphragmatic Hernia: An Ongoing Challenge von Brosens, Erwin, Peters, Nina C J, van Weelden, Kim S, Bendixen, Charlotte, Brouwer, Rutger W W, Sleutels, Frank, Bruggenwirth, Hennie T, van Ijcken, Wilfred F J, Veenma, Danielle C M, Otter, Suzan C M Cochius-Den, Wijnen, Rene M H, Eggink, Alex J, van Dooren, Marieke F, Reutter, Heiko Martin, Rottier, Robbert J, Schnater, J Marco, Tibboel, Dick, de Klein, Annelies

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