When mutants gain new powers: news from the mutant p53 field von Rotter, Varda, Brosh, Ran

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A critical role of PRDM14 in human primordial germ cell fate revealed by inducible degrons von Sybirna, Anastasiya, Tang, Walfred W. C., Pierson Smela, Merrick, Dietmann, Sabine, Gruhn, Wolfram H., Brosh, Ran, Surani, M. Azim

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Epigenetic polymorphism and the stochastic formation of differentially methylated regions in normal and cancerous tissues von Landan, Gilad, Cohen, Netta Mendelson, Mukamel, Zohar, Bar, Amir, Molchadsky, Alina, Brosh, Ran, Horn-Saban, Shirley, Zalcenstein, Daniela Amann, Goldfinger, Naomi, Zundelevich, Adi, Gal-Yam, Einav Nili, Rotter, Varda, Tanay, Amos

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Mutant p53 facilitates somatic cell reprogramming and augments the malignant potential of reprogrammed cells von Sarig, Rachel, Rivlin, Noa, Brosh, Ran, Bornstein, Chamutal, Kamer, Iris, Ezra, Osnat, Molchadsky, Alina, Goldfinger, Naomi, Brenner, Ori, Rotter, Varda

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Regulatory architecture of housekeeping genes is driven by promoter assemblies von Dejosez, Marion, Dall’Agnese, Alessandra, Ramamoorthy, Mahesh, Platt, Jesse, Yin, Xing, Hogan, Megan, Brosh, Ran, Weintraub, Abraham S., Hnisz, Denes, Abraham, Brian J., Young, Richard A., Zwaka, Thomas P.

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De novo assembly and delivery to mouse cells of a 101 kb functional human gene von Mitchell, Leslie A, McCulloch, Laura H, Pinglay, Sudarshan, Berger, Henri, Bosco, Nazario, Brosh, Ran, Bulajić, Milica, Huang, Emily, Hogan, Megan S, Martin, James A, Mazzoni, Esteban O, Davoli, Teresa, Maurano, Matthew T, Boeke, Jef D

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A dual molecular analogue tuner for dissecting protein function in mammalian cells von Brosh, Ran, Hrynyk, Iryna, Shen, Jessalyn, Waghray, Avinash, Zheng, Ning, Lemischka, Ihor R.

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TMPRSS2/ERG promotes epithelial to mesenchymal transition through the ZEB1/ZEB2 axis in a prostate cancer model von Leshem, Orit, Madar, Shalom, Kogan-Sakin, Ira, Kamer, Iris, Goldstein, Ido, Brosh, Ran, Cohen, Yehudit, Jacob-Hirsch, Jasmine, Ehrlich, Marcelo, Ben-Sasson, Shmuel, Goldfinger, Naomi, Loewenthal, Ron, Gazit, Ephraim, Rotter, Varda, Berger, Raanan

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Modulated expression of WFDC1 during carcinogenesis and cellular senescence von Madar, Shalom, Brosh, Ran, Buganim, Yosef, Ezra, Osnat, Goldstein, Ido, Solomon, Hilla, Kogan, Ira, Goldfinger, Naomi, Klocker, Helmut, Rotter, Varda

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p53-repressed miRNAs are involved with E2F in a feed-forward loop promoting proliferation von Harris, Curtis C, Ginsberg, Doron, Solomon, Hilla, Shalgi, Reut, Børresen-Dale, Anne-Lise, Goldstein, Ido, Enerly, Espen, Oren, Moshe, Brosh, Ran, Liran, Atar, Rotter, Varda, Landan, Gilad, Madar, Shalom, Korotayev, Katya, Johnsen, Hilde, Pilpel, Yitzhak, Nguyen, Giang Huong, Buganim, Yosef, Goldfinger, Naomi

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p53 Regulates the Ras Circuit to Inhibit the Expression of a Cancer-Related Gene Signature by Various Molecular Pathways von BUGANIM, Yosef, SOLOMON, Hilla, GORDIN, Maya, RIVLIN, Noa, KOGAN, Ira, BROSH, Ran, SEFADIA-ELAD, Galit, GOLDFINGER, Naomi, SIDRANSKY, David, KLOOG, Yoel, ROTTER, Varda, RAIS, Yoach, KISTNER, Daria, NACHMANY, Ido, BRAIT, Mariana, MADAR, Shalom, GOLDSTEIN, Ido, KALO, Eyal, ADAM, Nitzan

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A novel translocation breakpoint within the BPTF gene is associated with a pre-malignant phenotype von Buganim, Yosef, Goldstein, Ido, Lipson, Doron, Milyavsky, Michael, Polak-Charcon, Sylvie, Mardoukh, Corine, Solomon, Hilla, Kalo, Eyal, Madar, Shalom, Brosh, Ran, Perelman, Marina, Navon, Roy, Goldfinger, Naomi, Barshack, Iris, Yakhini, Zohar, Rotter, Varda

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SPATA18, a Spermatogenesis-Associated Gene, Is a Novel Transcriptional Target of p53 and p63 von Bornstein, Chamutal, Brosh, Ran, Molchadsky, Alina, Madar, Shalom, Kogan-Sakin, Ira, Goldstein, Ido, Chakravarti, Deepavali, Flores, Elsa R., Goldfinger, Naomi, Sarig, Rachel, Rotter, Varda

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A conditional counterselectable Piga knockout in mouse embryonic stem cells for advanced genome writing applications von Zhang, Weimin, Brosh, Ran, McCulloch, Laura H., Zhu, Yinan, Ashe, Hannah, Ellis, Gwen, Camellato, Brendan R., Kim, Sang Yong, Maurano, Matthew T., Boeke, Jef D.

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Structural Basis of Restoring Sequence-Specific DNA Binding and Transactivation to Mutant p53 by Suppressor Mutations von Suad, Oded, Rozenberg, Haim, Brosh, Ran, Diskin-Posner, Yael, Kessler, Naama, Shimon, Linda J.W., Frolow, Felix, Liran, Atar, Rotter, Varda, Shakked, Zippora

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Tbx3 Controls Dppa3 Levels and Exit from Pluripotency toward Mesoderm von Waghray, Avinash, Saiz, Néstor, Jayaprakash, Anitha D., Freire, Ana G., Papatsenko, Dmitri, Pereira, Carlos-Filipe, Lee, Dung-Fang, Brosh, Ran, Chang, Betty, Darr, Henia, Gingold, Julian, Kelley, Kevin, Schaniel, Christoph, Hadjantonakis, Anna-Katerina, Lemischka, Ihor R.

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p53-dependent transcriptional regulation of EDA2R and its involvement in chemotherapy-induced hair loss von Brosh, Ran, Sarig, Rachel, Natan, Elad Bar, Molchadsky, Alina, Madar, Shalom, Bornstein, Chamutal, Buganim, Yosef, Shapira, Tirosh, Goldfinger, Naomi, Paus, Ralf, Rotter, Varda

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Wide-scale analysis of human functional transcription factor binding reveals a strong bias towards the transcription start site von Tabach, Yuval, Brosh, Ran, Buganim, Yossi, Reiner, Anat, Zuk, Or, Yitzhaky, Assif, Koudritsky, Mark, Rotter, Varda, Domany, Eytan

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Mutations in the p53 Tumor Suppressor Gene: Important Milestones at the Various Steps of Tumorigenesis von Rivlin, Noa, Brosh, Ran, Oren, Moshe, Rotter, Varda

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Inactivation of Myocardin and p16 during Malignant Transformation Contributes to a Differentiation Defect von Milyavsky, Michael, Shats, Igor, Cholostoy, Alina, Brosh, Ran, Buganim, Yosef, Weisz, Lilach, Kogan, Ira, Cohen, Merav, Shatz, Maria, Madar, Shalom, Kalo, Eyal, Goldfinger, Naomi, Yuan, Jun, Ron, Shulamit, MacKenzie, Karen, Eden, Amir, Rotter, Varda

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