Loss of VPS13C Function in Autosomal-Recessive Parkinsonism Causes Mitochondrial Dysfunction and Increases PINK1/Parkin-Dependent Mitophagy von Lesage, Suzanne, Deramecourt, Vincent, Jacoupy, Maxime, Hassoun, Sidi Mohamed, Pujol, Claire, Maurage, Claude-Alain, Sahbatou, Mourad, Liebau, Stefan, Bilgic, Basar, Emre, Murat, Erginel-Unaltuna, Nihan, Guven, Gamze, Tison, François, Tranchant, Christine, Corvol, Jean-Christophe, Krack, Paul, Hernandez, Dena G., Gibbs, J. Raphael, Hardy, John, Wood, Nicholas W., Durr, Alexandra, Deleuze, Jean-François, Tazir, Meriem, Destée, Alain, Lohmann, Ebba, Corti, Olga, Brice, Alexis, Lesage, Suzanne, Tison, François, Vidailhet, Marie, Corvol, Jean-Christophe, Agid, Yves, Anheim, Mathieu, Bonnet, Anne-Marie, Borg, Michel, Broussolle, Emmanuel, Durif, Franck, Krack, Paul, Klebe, Stephan, Lohmann, Ebba, Vérin, Marc, Viallet, François, Brice, Alexis, Majounie, Elisa, Corvol, Jean Christophe, Ben-Shlomo, Yoav, Berg, Daniela, Bhatia, Kailash, Bochdanovits, Zoltan, Bonin, Michael, Bras, Jose M., Brockmann, Kathrin, Burn, David J., Chen, Honglei, Clarke, Carl E., Cookson, Mark R., Counsell, Carl, van Dijk, Karin D., Dong, Jing, Escott-Price, Valentina, Evans, Jonathan R., Gray, Emma, Guerreiro, Rita, van Hilten, Jacobus J., Hollenbeck, Albert, Holmans, Peter, Hu, Michèle, Hudson, Gavin, Hunt, Sarah E., Kilarski, Laura L., Jansen, Iris E., Langford, Cordelia, Lees, Andrew, Lorenz, Delia, Lubbe, Steven, Lungu, Codrin, Martinez, María, Mätzler, Walter, McNeill, Alisdair, Moorby, Catriona, O’Sullivan, Sean S., Pearson, Justin, Ravina, Bernard, Rivadeneira, Fernando, Ryten, Mina, Schapira, Anthony, Sharma, Manu, Sheerin, Una-Marie, Sidransky, Ellen, Spencer, Chris C.A., Stefánsson, Kári, Strange, Amy, Talbot, Kevin, Trabzuni, Daniah, Uitterlinden, André G., van de Warrenburg, Bart, Williams-Gray, Caroline H., Winder-Rhodes, Sophie, Hardy, John, Wood, Nicholas W.

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Large-scale meta-analysis of genome-wide association data identifies six new risk loci for Parkinson's disease von Nalls, Mike A, Pankratz, Nathan, Lill, Christina M, Do, Chuong B, Hernandez, Dena G, Saad, Mohamad, DeStefano, Anita L, Kara, Eleanna, Bras, Jose, Sharma, Manu, Schulte, Claudia, Keller, Margaux F, Arepalli, Sampath, Letson, Christopher, Edsall, Connor, Stefansson, Hreinn, Liu, Xinmin, Pliner, Hannah, Lee, Joseph H, Cheng, Rong, Ikram, M Arfan, Ioannidis, John P A, Hadjigeorgiou, Georgios M, Bis, Joshua C, Martinez, Maria, Perlmutter, Joel S, Goate, Alison, Marder, Karen, Fiske, Brian, Sutherland, Margaret, Xiromerisiou, Georgia, Myers, Richard H, Clark, Lorraine N, Stefansson, Kari, Hardy, John A, Heutink, Peter, Chen, Honglei, Wood, Nicholas W, Houlden, Henry, Payami, Haydeh, Brice, Alexis, Scott, William K, Gasser, Thomas, Bertram, Lars, Eriksson, Nicholas, Foroud, Tatiana, Singleton, Andrew B

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Excessive burden of lysosomal storage disorder gene variants in Parkinson's disease von Robak, Laurie A, Jansen, Iris E, van Rooij, Jeroen, Uitterlinden, André G, Kraaij, Robert, Jankovic, Joseph, Heutink, Peter, Shulman, Joshua M

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Unbiased screen for interactors of leucine-rich repeat kinase 2 supports a common pathway for sporadic and familial Parkinson disease von Beilina, Alexandria, Rudenko, Iakov N., Kaganovich, Alice, Civiero, Laura, Chau, Hien, Kalia, Suneil K., Kalia, Lorraine V., Lobbestael, Evy, Chia, Ruth, Ndukwe, Kelechi, Ding, Jinhui, Nalls, Mike A., Olszewski, Maciej, Hauser, David N., Kumaran, Ravindran, Lozano, Andres M., Baekelandt, Veerle, Greene, Lois E., Taymans, Jean-Marc, Greggio, Elisa, Cookson, Mark R.

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Mutational analysis of parkin and PINK1 in multiple system atrophy von Brooks, Janet A, Houlden, Henry, Melchers, Anna, Islam, Ansha J, Ding, Jinhui, Li, Abi, Paudel, Reema, Revesz, Tamas, Holton, Janice L, Wood, Nick, Lees, Andrew, Singleton, Andrew B, Scholz, Sonja W

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Imputation of sequence variants for identification of genetic risks for Parkinson's disease: a meta-analysis of genome-wide association studies von Nalls, Michael A, Plagnol, Vincent, Hernandez, Dena G, Sharma, Manu, Sheerin, Una-Marie, Saad, Mohamad, Simón-Sánchez, J, Schulte, Claudia, Lesage, Suzanne, Sveinbjörnsdóttir, Sigurlaug, Stefánsson, Kári, Martinez, Maria, Hardy, John, Heutink, Peter, Brice, Alexis, Gasser, Thomas, Singleton, Andrew B, Wood, Nicholas W

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Discovery and functional prioritization of Parkinson's disease candidate genes from large-scale whole exome sequencing von Jansen, Iris E, Ye, Hui, Heetveld, Sasja, Lechler, Marie C, Michels, Helen, Seinstra, Renée I, Lubbe, Steven J, Drouet, Valérie, Lesage, Suzanne, Majounie, Elisa, Gibbs, J Raphael, Nalls, Mike A, Ryten, Mina, Botia, Juan A, Vandrovcova, Jana, Simon-Sanchez, Javier, Castillo-Lizardo, Melissa, Rizzu, Patrizia, Blauwendraat, Cornelis, Chouhan, Amit K, Li, Yarong, Yogi, Puja, Amin, Najaf, van Duijn, Cornelia M, Morris, Huw R, Brice, Alexis, Singleton, Andrew B, David, Della C, Nollen, Ellen A, Jain, Shushant, Shulman, Joshua M, Heutink, Peter

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A two-stage meta-analysis identifies several new loci for Parkinson's disease

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Using genome-wide complex trait analysis to quantify 'missing heritability' in Parkinson's disease von KELLER, Margaux F, SAAD, Mohamad, SCHULTE, Claudia, MOSKVINA, Valentina, DURR, Alexandra, HOLMANS, Peter, KILARSKI, Laura L, GUERREIRO, Rita, HERNANDEZ, Dena G, BRICE, Alexis, YLIKOTILA, Pauli, STEFANSSON, Hreinn, BRAS, Jose, MAJAMAA, Kari, MORRIS, Huw R, WILLIAMS, Nigel, GASSER, Thomas, HEUTINK, Peter, WOOD, Nicholas W, HARDY, John, MARTINEZ, Maria, SINGLETON, Andrew B, NALLS, Michael A, BETTELLA, Francesco, NICOLAOU, Nayia, SIMON-SANCHEZ, Javier, MITTAG, Florian, BÜCHEL, Finja, SHARMA, Manu, RAPHAEL GIBBS, J

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Serum iron levels and the risk of Parkinson disease: a Mendelian randomization study von Pichler, Irene, Del Greco M, Fabiola, Gögele, Martin, Lill, Christina M, Bertram, Lars, Do, Chuong B, Eriksson, Nicholas, Foroud, Tatiana, Myers, Richard H, Nalls, Michael, Keller, Margaux F, Benyamin, Beben, Whitfield, John B, Pramstaller, Peter P, Hicks, Andrew A, Thompson, John R, Minelli, Cosetta

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NeuroX, a fast and efficient genotyping platform for investigation of neurodegenerative diseases von Nalls, Mike A, Bras, Jose, Hernandez, Dena G, Keller, Margaux F, Majounie, Elisa, Renton, Alan E, Saad, Mohamad, Jansen, Iris, Guerreiro, Rita, Lubbe, Steven, Plagnol, Vincent, Gibbs, J. Raphael, Schulte, Claudia, Pankratz, Nathan, Sutherland, Margaret, Bertram, Lars, Lill, Christina M, DeStefano, Anita L, Faroud, Tatiana, Eriksson, Nicholas, Tung, Joyce Y, Edsall, Connor, Nichols, Noah, Brooks, Janet, Arepalli, Sampath, Pliner, Hannah, Letson, Chris, Heutink, Peter, Martinez, Maria, Gasser, Thomas, Traynor, Bryan J, Wood, Nick, Hardy, John, Singleton, Andrew B

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A pathway-based analysis provides additional support for an immune-related genetic susceptibility to Parkinson's disease von Holmans, Peter, Moskvina, Valentina, Jones, Lesley, Sharma, Manu, Vedernikov, Alexey, Buchel, Finja, Saad, Mohamad, Sadd, Mohamad, Bras, Jose M, Bettella, Francesco, Nicolaou, Nayia, Simón-Sánchez, Javier, Mittag, Florian, Gibbs, J Raphael, Schulte, Claudia, Durr, Alexandra, Guerreiro, Rita, Hernandez, Dena, Brice, Alexis, Stefánsson, Hreinn, Majamaa, Kari, Gasser, Thomas, Heutink, Peter, Wood, Nicholas W, Martinez, Maria, Singleton, Andrew B, Nalls, Michael A, Hardy, John, Morris, Huw R, Williams, Nigel M

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Genetic comorbidities in Parkinson's disease von Nalls, Mike A, Saad, Mohamad, Noyce, Alastair J, Keller, Margaux F, Schrag, Anette, Bestwick, Jonathan P, Traynor, Bryan J, Gibbs, J Raphael, Hernandez, Dena G, Cookson, Mark R, Morris, Huw R, Williams, Nigel, Gasser, Thomas, Heutink, Peter, Wood, Nick, Hardy, John, Martinez, Maria, Singleton, Andrew B

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Analysis of Genome-Wide Association Studies of Alzheimer Disease and of Parkinson Disease to Determine If These 2 Diseases Share a Common Genetic Risk von Moskvina, Valentina, Harold, Denise, Russo, GianCarlo, Vedernikov, Alexey, Sharma, Manu, Saad, Mohamad, Holmans, Peter, Bras, Jose M, Bettella, Francesco, Keller, Margaux F, Nicolaou, Nayia, Simón-Sánchez, Javier, Gibbs, J. Raphael, Schulte, Claudia, Durr, Alexandra, Guerreiro, Rita, Hernandez, Dena, Brice, Alexis, Stefánsson, Hreinn, Majamaa, Kari, Gasser, Thomas, Heutink, Peter, Wood, Nick, Martinez, Maria, Singleton, Andrew B, Nalls, Michael A, Hardy, John, Owen, Michael J, O’Donovan, Michael C, Williams, Julie, Morris, Huw R, Williams, Nigel M

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The Val158Met COMT polymorphism is a modifier of the age at onset in Parkinson's disease with a sexual dimorphism von Klebe, Stephan, Golmard, Jean-Louis, Nalls, Michael A, Saad, Mohamad, Singleton, Andrew B, Bras, Jose M, Hardy, John, Simon-Sanchez, Javier, Heutink, Peter, Kuhlenbäumer, Gregor, Charfi, Rim, Klein, Christine, Hagenah, Johann, Gasser, Thomas, Wurster, Isabel, Lesage, Suzanne, Lorenz, Delia, Deuschl, Günther, Durif, Franck, Pollak, Pierre, Damier, Philippe, Tison, François, Durr, Alexandra, Amouyel, Philippe, Lambert, Jean-Charles, Tzourio, Christophe, Maubaret, Cécilia, Charbonnier-Beaupel, Fanny, Tahiri, Khadija, Vidailhet, Marie, Martinez, Maria, Brice, Alexis, Corvol, Jean-Christophe

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Susceptibility loci for pigmentation and melanoma in relation to Parkinson's disease von Dong, Jing, Gao, Jianjun, Nalls, Michael, Gao, Xiang, Huang, Xuemei, Han, Jiali, Singleton, Andrew B, Chen, Honglei

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Use of support vector machines for disease risk prediction in genome-wide association studies: Concerns and opportunities von Mittag, Florian, Büchel, Finja, Saad, Mohamad, Jahn, Andreas, Schulte, Claudia, Bochdanovits, Zoltan, Simón-Sánchez, Javier, Nalls, Mike A., Keller, Margaux, Hernandez, Dena G., Gibbs, J. Raphael, Lesage, Suzanne, Brice, Alexis, Heutink, Peter, Martinez, Maria, Wood, Nicholas W, Hardy, John, Singleton, Andrew B., Zell, Andreas, Gasser, Thomas, Sharma, Manu

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DNA damage and radiocesium in channel catfish from chernobyl von Sugg, Derrick W., Brooks, Janet A., Jagoe, Charles H., Smith, Michael H., Chesser, Ronald K., Bickham, John W., Lomakin, Michael D., Dallas, Cham E., Baker, Robert J.

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Heterogeneity of T-Cell Receptor α-Chain Complementarity-Determining Region 3 in Myelin Basic Protein-Specific T Cells Increases with Severity of Multiple Sclerosis von Utz, Ursula, Brooks, Janet A., McFarland, Henry F., Martin, Roland, Biddison, William E.

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