Cancer-Associated PTEN Mutants Act in a Dominant-Negative Manner to Suppress PTEN Protein Function von Papa, Antonella, Wan, Lixin, Bonora, Massimo, Salmena, Leonardo, Song, Min Sup, Hobbs, Robin M., Lunardi, Andrea, Webster, Kaitlyn, Ng, Christopher, Newton, Ryan H., Knoblauch, Nicholas, Guarnerio, Jlenia, Ito, Keisuke, Turka, Laurence A., Beck, Andy H., Pinton, Paolo, Bronson, Roderick T., Wei, Wenyi, Pandolfi, Pier Paolo

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Mosaic Analysis with Double Markers Reveals Tumor Cell of Origin in Glioma von Liu, Chong, Sage, Jonathan C., Miller, Michael R., Verhaak, Roel G.W., Hippenmeyer, Simon, Vogel, Hannes, Foreman, Oded, Bronson, Roderick T., Nishiyama, Akiko, Luo, Liqun, Zong, Hui

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G1 cyclins link proliferation, pluripotency and differentiation of embryonic stem cells von Liu, Lijun, Michowski, Wojciech, Inuzuka, Hiroyuki, Shimizu, Kouhei, Nihira, Naoe Taira, Chick, Joel M., Li, Na, Geng, Yan, Meng, Alice Y., Ordureau, Alban, Kołodziejczyk, Aleksandra, Ligon, Keith L., Bronson, Roderick T., Polyak, Kornelia, Harper, J. Wade, Gygi, Steven P., Wei, Wenyi, Sicinski, Piotr

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The CD155/TIGIT axis promotes and maintains immune evasion in neoantigen-expressing pancreatic cancer von Freed-Pastor, William A., Lambert, Laurens J., Ely, Zackery A., Pattada, Nimisha B., Bhutkar, Arjun, Eng, George, Mercer, Kim L., Garcia, Ana P., Lin, Lin, Rideout, William M., Hwang, William L., Schenkel, Jason M., Jaeger, Alex M., Bronson, Roderick T., Westcott, Peter M.K., Hether, Tyler D., Divakar, Prajan, Reeves, Jason W., Deshpande, Vikram, Delorey, Toni, Phillips, Devan, Yilmaz, Omer H., Regev, Aviv, Jacks, Tyler

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Regulatory T Cells in Tumor-Associated Tertiary Lymphoid Structures Suppress Anti-tumor T Cell Responses von Joshi, Nikhil S., Akama-Garren, Elliot H., Lu, Yisi, Lee, Da-Yae, Chang, Gregory P., Li, Amy, DuPage, Michel, Tammela, Tuomas, Kerper, Natanya R., Farago, Anna F., Robbins, Rebecca, Crowley, Denise M., Bronson, Roderick T., Jacks, Tyler

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Oncogenic KRAS supports pancreatic cancer through regulation of nucleotide synthesis von Santana-Codina, Naiara, Roeth, Anjali A., Zhang, Yi, Yang, Annan, Mashadova, Oksana, Asara, John M., Wang, Xiaoxu, Bronson, Roderick T., Lyssiotis, Costas A., Ying, Haoqiang, Kimmelman, Alec C.

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Parathyroid Hormone Directs Bone Marrow Mesenchymal Cell Fate von Fan, Yi, Hanai, Jun-ichi, Le, Phuong T., Bi, Ruiye, Maridas, David, DeMambro, Victoria, Figueroa, Carolina A., Kir, Serkan, Zhou, Xuedong, Mannstadt, Michael, Baron, Roland, Bronson, Roderick T., Horowitz, Mark C., Wu, Joy Y., Bilezikian, John P., Dempster, David W., Rosen, Clifford J., Lanske, Beate

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Engineered bacteria can function in the mammalian gut long-term as live diagnostics of inflammation von Riglar, David T, Giessen, Tobias W, Baym, Michael, Kerns, S Jordan, Niederhuber, Matthew J, Bronson, Roderick T, Kotula, Jonathan W, Gerber, Georg K, Way, Jeffrey C, Silver, Pamela A

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Inflammation and disintegration of intestinal villi in an experimental model for Vibrio parahaemolyticus-induced diarrhea von Ritchie, Jennifer M, Rui, Haopeng, Zhou, Xiaohui, Iida, Tetsuya, Kodoma, Toshio, Ito, Susuma, Davis, Brigid M, Bronson, Roderick T, Waldor, Matthew K

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Cancer Cells Co-opt the Neuronal Redox-Sensing Channel TRPA1 to Promote Oxidative-Stress Tolerance von Takahashi, Nobuaki, Chen, Hsing-Yu, Harris, Isaac S., Stover, Daniel G., Selfors, Laura M., Bronson, Roderick T., Deraedt, Thomas, Cichowski, Karen, Welm, Alana L., Mori, Yasuo, Mills, Gordon B., Brugge, Joan S.

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PARP Inhibition Elicits STING-Dependent Antitumor Immunity in Brca1-Deficient Ovarian Cancer von Ding, Liya, Kim, Hye-Jung, Wang, Qiwei, Kearns, Michael, Jiang, Tao, Ohlson, Carolynn E., Li, Ben B., Xie, Shaozhen, Liu, Joyce F., Stover, Elizabeth H., Howitt, Brooke E., Bronson, Roderick T., Lazo, Suzan, Roberts, Thomas M., Freeman, Gordon J., Konstantinopoulos, Panagiotis A., Matulonis, Ursula A., Zhao, Jean J.

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Class IIa HDAC inhibition reduces breast tumours and metastases through anti-tumour macrophages von Guerriero, Jennifer L., Sotayo, Alaba, Ponichtera, Holly E., Castrillon, Jessica A., Pourzia, Alexandra L., Schad, Sara, Johnson, Shawn F., Carrasco, Ruben D., Lazo, Suzan, Bronson, Roderick T., Davis, Scott P., Lobera, Mercedes, Nolan, Michael A., Letai, Anthony

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Hepatocyte Deletion of Triglyceride‐Synthesis Enzyme Acyl CoA: Diacylglycerol Acyltransferase 2 Reduces Steatosis Without Increasing Inflammation or Fibrosis in Mice von Gluchowski, Nina L., Gabriel, Katlyn R., Chitraju, Chandramohan, Bronson, Roderick T., Mejhert, Niklas, Boland, Sebastian, Wang, Kun, Lai, Zon Weng, Farese, Robert V., Walther, Tobias C.

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MTDH-SND1 Interaction Is Crucial for Expansion and Activity of Tumor-Initiating Cells in Diverse Oncogene- and Carcinogen-Induced Mammary Tumors von Wan, Liling, Lu, Xin, Yuan, Salina, Wei, Yong, Guo, Feng, Shen, Minhong, Yuan, Min, Chakrabarti, Rumela, Hua, Yuling, Smith, Heath A., Blanco, Mario Andres, Chekmareva, Marina, Wu, Hao, Bronson, Roderick T., Haffty, Bruce G., Xing, Yongna, Kang, Yibin

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Exploiting Cancer Cell Vulnerabilities to Develop a Combination Therapy for Ras-Driven Tumors von De Raedt, Thomas, Walton, Zandra, Yecies, Jessica L., Li, Danan, Chen, Yimei, Malone, Clare F., Maertens, Ophélia, Jeong, Seung Min, Bronson, Roderick T., Lebleu, Valerie, Kalluri, Raghu, Normant, Emmanuel, Haigis, Marcia C., Manning, Brendan D., Wong, Kwok-Kin, Macleod, Kay F., Cichowski, Karen

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Germline loss of PKM2 promotes metabolic distress and hepatocellular carcinoma von Dayton, Talya L, Gocheva, Vasilena, Miller, Kathryn M, Israelsen, William J, Bhutkar, Arjun, Clish, Clary B, Davidson, Shawn M, Luengo, Alba, Bronson, Roderick T, Jacks, Tyler, Vander Heiden, Matthew G

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CRISPR-mediated modeling and functional validation of candidate tumor suppressor genes in small cell lung cancer von Ng, Sheng Rong, Rideout, William M., Akama-Garren, Elliot H., Bhutkar, Arjun, Mercer, Kim L., Schenkel, Jason M., Bronson, Roderick T., Jacks, Tyler

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Adaptations to a Subterranean Environment and Longevity Revealed by the Analysis of Mole Rat Genomes von Fang, Xiaodong, Seim, Inge, Huang, Zhiyong, Gerashchenko, Maxim V., Xiong, Zhiqiang, Turanov, Anton A., Zhu, Yabing, Lobanov, Alexei V., Fan, Dingding, Yim, Sun Hee, Yao, Xiaoming, Ma, Siming, Yang, Lan, Lee, Sang-Goo, Kim, Eun Bae, Bronson, Roderick T., Šumbera, Radim, Buffenstein, Rochelle, Zhou, Xin, Krogh, Anders, Park, Thomas J., Zhang, Guojie, Wang, Jun, Gladyshev, Vadim N.

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CRISPR-mediated direct mutation of cancer genes in the mouse liver von Xue, Wen, Chen, Sidi, Yin, Hao, Tammela, Tuomas, Papagiannakopoulos, Thales, Joshi, Nikhil S., Cai, Wenxin, Yang, Gillian, Bronson, Roderick, Crowley, Denise G., Zhang, Feng, Anderson, Daniel G., Sharp, Phillip A., Jacks, Tyler

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Rapid modelling of cooperating genetic events in cancer through somatic genome editing von Sánchez-Rivera, Francisco J., Papagiannakopoulos, Thales, Romero, Rodrigo, Tammela, Tuomas, Bauer, Matthew R., Bhutkar, Arjun, Joshi, Nikhil S., Subbaraj, Lakshmipriya, Bronson, Roderick T., Xue, Wen, Jacks, Tyler

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