Rationale for anti-GITR cancer immunotherapy von Knee, Deborah A, Hewes, Becker, Brogdon, Jennifer L

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Genetic mechanisms of target antigen loss in CAR19 therapy of acute lymphoblastic leukemia von Orlando, Elena J., Han, Xia, Tribouley, Catherine, Wood, Patricia A., Leary, Rebecca J., Riester, Markus, Levine, John E., Qayed, Muna, Grupp, Stephan A., Boyer, Michael, De Moerloose, Barbara, Nemecek, Eneida R., Bittencourt, Henrique, Hiramatsu, Hidefumi, Buechner, Jochen, Davies, Stella M., Verneris, Michael R., Nguyen, Kevin, Brogdon, Jennifer L., Bitter, Hans, Morrissey, Michael, Pierog, Piotr, Pantano, Serafino, Engelman, Jeffrey A., Winckler, Wendy

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Chimeric Antigen Receptor T Cells in Refractory B-Cell Lymphomas von Schuster, Stephen J, Svoboda, Jakub, Chong, Elise A, Nasta, Sunita D, Mato, Anthony R, Anak, Özlem, Brogdon, Jennifer L, Pruteanu-Malinici, Iulian, Bhoj, Vijay, Landsburg, Daniel, Wasik, Mariusz, Levine, Bruce L, Lacey, Simon F, Melenhorst, Jan J, Porter, David L, June, Carl H

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OX40 engagement depletes intratumoral Tregs via activating FcγRs, leading to antitumor efficacy von Bulliard, Yannick, Jolicoeur, Rose, Zhang, Jimin, Dranoff, Glenn, Wilson, Nicholas S, Brogdon, Jennifer L

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Decade-long leukaemia remissions with persistence of CD4+ CAR T cells von Melenhorst, J. Joseph, Chen, Gregory M., Wang, Meng, Porter, David L., Chen, Changya, Collins, McKensie A., Gao, Peng, Bandyopadhyay, Shovik, Sun, Hongxing, Zhao, Ziran, Lundh, Stefan, Pruteanu-Malinici, Iulian, Nobles, Christopher L., Maji, Sayantan, Frey, Noelle V., Gill, Saar I., Loren, Alison W., Tian, Lifeng, Kulikovskaya, Irina, Gupta, Minnal, Ambrose, David E., Davis, Megan M., Fraietta, Joseph A., Brogdon, Jennifer L., Young, Regina M., Chew, Anne, Levine, Bruce L., Siegel, Donald L., Alanio, Cécile, Wherry, E. John, Bushman, Frederic D., Lacey, Simon F., Tan, Kai, June, Carl H.

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B cell maturation antigen-specific CAR T cells are clinically active in multiple myeloma von Cohen, Adam D, Garfall, Alfred L, Stadtmauer, Edward A, Melenhorst, J Joseph, Lacey, Simon F, Lancaster, Eric, Vogl, Dan T, Weiss, Brendan M, Dengel, Karen, Nelson, Annemarie, Plesa, Gabriela, Chen, Fang, Davis, Megan M, Hwang, Wei-Ting, Young, Regina M, Brogdon, Jennifer L, Isaacs, Randi, Pruteanu-Malinici, Iulian, Siegel, Don L, Levine, Bruce L, June, Carl H, Milone, Michael C

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Activating Fc γ receptors contribute to the antitumor activities of immunoregulatory receptor-targeting antibodies von Bulliard, Yannick, Jolicoeur, Rose, Windman, Maurice, Rue, Sarah M, Ettenberg, Seth, Knee, Deborah A, Wilson, Nicholas S, Dranoff, Glenn, Brogdon, Jennifer L

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Determinants of response and resistance to CD19 chimeric antigen receptor (CAR) T cell therapy of chronic lymphocytic leukemia von Fraietta, Joseph A., Lacey, Simon F., Orlando, Elena J., Pruteanu-Malinici, Iulian, Gohil, Mercy, Lundh, Stefan, Boesteanu, Alina C., Wang, Yan, O’Connor, Roddy S., Hwang, Wei-Ting, Pequignot, Edward, Ambrose, David E., Zhang, Changfeng, Wilcox, Nicholas, Bedoya, Felipe, Dorfmeier, Corin, Chen, Fang, Tian, Lifeng, Parakandi, Harit, Gupta, Minnal, Young, Regina M., Johnson, F. Brad, Kulikovskaya, Irina, Liu, Li, Xu, Jun, Kassim, Sadik H., Davis, Megan M., Levine, Bruce L., Frey, Noelle V., Siegel, Donald L., Huang, Alexander C., Wherry, E. John, Bitter, Hans, Brogdon, Jennifer L., Porter, David L., June, Carl H., Melenhorst, J. Joseph

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Humanized CD19-Targeted Chimeric Antigen Receptor (CAR) T Cells in CAR-Naive and CAR-Exposed Children and Young Adults With Relapsed or Refractory Acute Lymphoblastic Leukemia von Myers, Regina M., Li, Yimei, Leahy, Allison Barz, Barrett, David M., Teachey, David T., Callahan, Colleen, Fasano, Christina C., Rheingold, Susan R., DiNofia, Amanda, Wray, Lisa, Aplenc, Richard, Baniewicz, Diane, Liu, Hongyan, Shaw, Pamela A., Pequignot, Edward, Getz, Kelly D., Brogdon, Jennifer L., Fesnak, Andrew D., Siegel, Donald L., Davis, Megan M., Bartoszek, Chelsie, Lacey, Simon F., Hexner, Elizabeth O., Chew, Anne, Wertheim, Gerald B., Levine, Bruce L., June, Carl H., Grupp, Stephan A., Maude, Shannon L.

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Antigen-independent activation enhances the efficacy of 4-1BB-costimulated CD22 CAR T cells von Singh, Nathan, Frey, Noelle V., Engels, Boris, Barrett, David M., Shestova, Olga, Ravikumar, Pranali, Cummins, Katherine D., Lee, Yong Gu, Pajarillo, Raymone, Chun, Inkook, Shyu, Amy, Highfill, Steven L., Price, Andrew, Zhao, Linlin, Peng, Liaomin, Granda, Brian, Ramones, Melissa, Lu, Xueqing Maggie, Christian, David A., Perazzelli, Jessica, Lacey, Simon F., Roy, Nathan H., Burkhardt, Janis K., Colomb, Florent, Damra, Mohammad, Abdel-Mohsen, Mohamed, Liu, Ting, Liu, Dongfang, Standley, Daron M., Young, Regina M., Brogdon, Jennifer L., Grupp, Stephan A., June, Carl H., Maude, Shannon L., Gill, Saar, Ruella, Marco

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A Novel Autologous CAR-T Therapy, YTB323, with Preserved T-Cell Stemness Shows Enhanced CAR T-Cell Efficacy in Preclinical and Early Clinical Development von Dickinson, Michael J, Barba, Pere, Jager, Ulrich, Shah, Nirav N, Blaise, Didier, Briones, Javier, Shune, Leyla, Boissel, Nicolas, Bondanza, Attilio, Mariconti, Luisa, Marchal, Anne-Laure, Quinn, David S, Yang, Jennifer, Price, Andrew, Sohoni, Akash, Treanor, Louise M, Orlando, Elena J, Mataraza, Jennifer, Davis, Jaclyn, Lu, Darlene, Zhu, Xu, Engels, Boris, Moutouh-de Parseval, Laure, Brogdon, Jennifer L, Moschetta, Michele, Flinn, Ian W

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Two cases of severe pulmonary toxicity from highly active mesothelin-directed CAR T cells von Haas, Andrew R., Golden, Ryan J., Litzky, Leslie A., Engels, Boris, Zhao, Linlin, Xu, Fangmin, Taraszka, John A., Ramones, Melissa, Granda, Brian, Chang, Wan-Jung, Jadlowsky, Julie, Shea, Kim-Marie, Runkle, Adam, Chew, Anne, Dowd, Emily, Gonzalez, Vanessa, Chen, Fang, Liu, Xiaojun, Fang, Chongyun, Jiang, Shuguang, Davis, Megan M., Sheppard, Neil C., Zhao, Yangbing, Fraietta, Joseph A., Lacey, Simon F., Plesa, Gabriela, Melenhorst, J. Joseph, Mansfield, Keith, Brogdon, Jennifer L., Young, Regina M., Albelda, Steven M., June, Carl H., Tanyi, Janos L.

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Cytokine-mediated CAR T therapy resistance in AML von Bhagwat, Anand S, Torres, Leonel, Shestova, Olga, Shestov, Maksim, Mellors, Patrick W, Fisher, Han R, Farooki, Saamia N, Frost, Benjamin F, Loken, Michael R, Gaymon, Avery L, Frazee, Diane, Rogal, Walter, Frey, Noelle, Hexner, Elizabeth O, Luger, Selina M, Loren, Alison W, Martin, Mary Ellen, McCurdy, Shannon R, Perl, Alexander E, Stadtmauer, Edward A, Brogdon, Jennifer L, Fraietta, Joseph A, Hwang, Wei-Ting, Siegel, Don L, Plesa, Gabriela, Aplenc, Richard, Porter, David L, June, Carl H, Gill, Saar I

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Anti-CD19 CAR T cells in combination with ibrutinib for the treatment of chronic lymphocytic leukemia von Gill, Saar, Vides, Vanessa, Frey, Noelle V., Hexner, Elizabeth O., Metzger, Susan, O'Brien, Megan, Hwang, Wei-Ting, Brogdon, Jennifer L., Davis, Megan M., Fraietta, Joseph A., Gaymon, Avery L., Gladney, Whitney L., Lacey, Simon F., Lamontagne, Anne, Mato, Anthony R., Maus, Marcela V., Melenhorst, J. Joseph, Pequignot, Edward, Ruella, Marco, Shestov, Maksim, Byrd, John C., Schuster, Stephen J., Siegel, Donald L., Levine, Bruce L., June, Carl H., Porter, David L.

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Histone deacetylase activities are required for innate immune cell control of Th1 but not Th2 effector cell function von Brogdon, Jennifer L., Xu, Yongyao, Szabo, Susanne J., An, Shaojian, Buxton, Francis, Cohen, Dalia, Huang, Qian

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An IMiD-inducible degron provides reversible regulation for chimeric antigen receptor expression and activity von Carbonneau, Seth, Sharma, Sujata, Peng, Liaomin, Rajan, Vaisakh, Hainzl, Dominik, Henault, Martin, Yang, Chian, Hale, Jacob, Shulok, Janine, Tallarico, John, Porter, Jeff, Brogdon, Jennifer L., Dranoff, Glenn, Bradner, James E., Hild, Marc, Guimaraes, Carla P.

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Author Correction: Decade-long leukaemia remissions with persistence of CD4+ CAR T cells von Melenhorst, J. Joseph, Chen, Gregory M., Wang, Meng, Porter, David L., Chen, Changya, Collins, McKensie A., Gao, Peng, Bandyopadhyay, Shovik, Sun, Hongxing, Zhao, Ziran, Lundh, Stefan, Pruteanu-Malinici, Iulian, Nobles, Christopher L., Maji, Sayantan, Frey, Noelle V., Gill, Saar I., Loren, Alison W., Tian, Lifeng, Kulikovskaya, Irina, Gupta, Minnal, Ambrose, David E., Davis, Megan M., Fraietta, Joseph A., Brogdon, Jennifer L., Young, Regina M., Chew, Anne, Levine, Bruce L., Siegel, Donald L., Alanio, Cécile, Wherry, E. John, Bushman, Frederic D., Lacey, Simon F., Tan, Kai, June, Carl H.

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Repeated peripheral infusions of anti-EGFRvIII CAR T cells in combination with pembrolizumab show no efficacy in glioblastoma: a phase 1 trial von Bagley, Stephen J, Binder, Zev A, Lamrani, Lamia, Marinari, Eliana, Desai, Arati S, Nasrallah, MacLean P, Maloney, Eileen, Brem, Steven, Lustig, Robert A, Kurtz, Goldie, Alonso-Basanta, Michelle, Bonté, Pierre-Emmanuel, Goudot, Christel, Richer, Wilfrid, Piaggio, Eliane, Kothari, Shawn, Guyonnet, Lea, Guerin, Coralie L, Waterfall, Joshua J, Mohan, Suyash, Hwang, Wei-Ting, Tang, Oliver Y, Logun, Meghan, Bhattacharyya, Meghna, Markowitz, Kelly, Delman, Devora, Marshall, Amy, Wherry, E John, Amigorena, Sebastian, Beatty, Gregory L, Brogdon, Jennifer L, Hexner, Elizabeth, Migliorini, Denis, Alanio, Cecile, O'Rourke, Donald M

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Monitoring of tisagenlecleucel transgene DNA using a quantitative polymerase chain reaction assay von Davis, Lisa, Riccitelli, Nathan, Valencia, Nancy, Ch’en, Irene L., Tangri, Shabnam, Brogdon, Jennifer L., Kalfoglou, Creton, Mueller, Karen Thudium, Pollner, Reinhold

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Anti-BCMA/CD19 CAR T Cells with Early Immunomodulatory Maintenance for Multiple Myeloma Responding to Initial or Later-Line Therapy von Garfall, Alfred L, Cohen, Adam D, Susanibar-Adaniya, Sandra P, Hwang, Wei-Ting, Vogl, Dan T, Waxman, Adam J, Lacey, Simon F, Gonzalez, Vanessa E, Fraietta, Joseph A, Gupta, Minnal, Kulikovskaya, Irina, Tian, Lifeng, Chen, Fang, Koterba, Natalka, Bartoszek, Robert L, Patchin, Margaret, Xu, Rong, Plesa, Gabriela, Siegel, Don L, Brennan, Andrea, Nelson, Anne Marie, Ferthio, Regina, Cosey, Angela, Shea, Kim-Marie, Leskowitz, Rachel, Four, Megan, Wilson, Wesley V, Miao, Fei, Lancaster, Eric, Carreno, Beatriz M, Linette, Gerald P, Hexner, Elizabeth O, Young, Regina M, Bu, Dexiu, Mansfield, Keith G, Brogdon, Jennifer L, June, Carl H, Milone, Michael C, Stadtmauer, Edward A

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