The “unnatural” history of colorectal cancer in Lynch syndrome: Lessons from colonoscopy surveillance von Ahadova, Aysel, Seppälä, Toni T., Engel, Christoph, Gallon, Richard, Burn, John, Holinski‐Feder, Elke, Steinke‐Lange, Verena, Möslein, Gabriela, Nielsen, Maartje, Broeke, Sanne W., Laghi, Luigi, Dominguez‐Valentin, Mev, Capella, Gabriel, Macrae, Finlay, Scott, Rodney, Hüneburg, Robert, Nattermann, Jacob, Hoffmeister, Michael, Brenner, Hermann, Bläker, Hendrik, Knebel Doeberitz, Magnus, Sampson, Julian R., Vasen, Hans, Mecklin, Jukka‐Pekka, Møller, Pål, Kloor, Matthias

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Delineating genotype and parent‐of‐origin effect on the phenotype in MSH6‐associated Lynch syndrome von Werf‐'t Lam, Anne‐Sophie, Rodriguez‐Girondo, Mar, Villasmil, Mandy, Tops, Carli M., Hest, Liselotte, Gille, Hans J. P., Duijkers, Floor A. M., Wagner, Anja, Eikenboom, Ellis, Letteboer, Tom G. W., Jong, Mirjam M., Bajwa‐ten Broeke, Sanne W., Bleeker, Fonnet, Gomez Garcia, Encarna B., Dominguez‐Valentin, Mev, Møller, Pal, Suerink, Manon, Nielsen, Maartje

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Response to Roberts et al. 2018: is breast cancer truly caused by MSH6 and PMS2 variants or is it simply due to a high prevalence of these variants in the population? von ten Broeke, S.W., Suerink, M., Nielsen, M.

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The diverse molecular profiles of lynch syndrome-associated colorectal cancers are (highly) dependent on underlying germline mismatch repair mutations von Helderman, Noah C., Bajwa - ten Broeke, Sanne W., Morreau, Hans, Suerink, Manon, Terlouw, Diantha, van der Werf-’ t Lam, Anne-Sophie, van Wezel, Tom, Nielsen, Maartje

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Molecular Background of Colorectal Tumors From Patients With Lynch Syndrome Associated With Germline Variants in PMS2 von ten Broeke, Sanne W., van Bavel, Tom C., Jansen, Anne M.L., Gómez-García, Encarnca, Hes, Frederik J., van Hest, Liselot P., Letteboer, Tom G.W., Olderode-Berends, Maran J.W., Ruano, Dina, Spruijt, Liesbeth, Suerink, Manon, Tops, Carli M., van Eijk, Ronald, Morreau, Hans, van Wezel, Tom, Nielsen, Maartje

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The coding microsatellite mutation profile of PMS2-deficient colorectal cancer von Bajwa - ten Broeke, Sanne W., Ballhausen, Alexej, Ahadova, Aysel, Suerink, Manon, Bohaumilitzky, Lena, Seidler, Florian, Morreau, Hans, van Wezel, Tom, Krzykalla, Julia, Benner, Axel, de Miranda, Noel F., von Knebel Doeberitz, Magnus, Nielsen, Maartje, Kloor, Matthias

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Discordant Staining Patterns and Microsatellite Results in Tumors of MSH6 Pathogenic Variant Carriers von van der Werf-’t Lam, Anne-Sophie, Terlouw, Diantha, Tops, Carli M., van Kan, Merel S., van Hest, Liselotte P., Gille, Hans J.P., Duijkers, Floor A.M., Wagner, Anja, Eikenboom, Ellis L., Letteboer, Tom G.W., de Jong, Mirjam M., Bajwa-ten Broeke, Sanne W., Bleeker, Fonnet E., Gomez Garcia, Encarna B., de Wind, Niels, van Wezel, J. Tom, Morreau, Hans, Suerink, Manon, Nielsen, Maartje

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PMS2-associated Lynch syndrome: Past, present and future von Andini, Katarina D, Nielsen, Maartje, Suerink, Manon, Helderman, Noah C, Koornstra, Jan Jacob, Ahadova, Aysel, Kloor, Matthias, Mourits, Marian J E, Kok, Klaas, Sijmons, Rolf H, Bajwa-Ten Broeke, Sanne W

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Declining detection rates for APC and biallelic MUTYH variants in polyposis patients, implications for DNA testing policy von Terlouw, Diantha, Suerink, Manon, Singh, Sunny S, Gille, Hans J J P, Hes, Frederik J, Langers, Alexandra M J, Morreau, Hans, Vasen, Hans F A, Vos, Yvonne J, van Wezel, Tom, Tops, Carli M, Ten Broeke, Sanne W, Nielsen, Maartje

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Constitutional mismatch repair deficiency in a healthy child: On the spot diagnosis? von Suerink, M., Potjer, T.P., Versluijs, A.B., ten Broeke, S.W., Tops, C.M., Wimmer, K., Nielsen, M.

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Breaking Traditions: An Isotopic Study on the Changing Funerary Practices in the Dutch Iron Age (800–12 bc) von Kootker, L. M., Geerdink, C., Broeke, P. W., Kars, H., Davies, G. R.

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The Apparent Genetic Anticipation in PMS2-Associated Lynch Syndrome Families Is Explained by Birth-cohort Effect von Ten Broeke, Sanne W, Rodríguez-Girondo, Mar, Suerink, Manon, Aretz, Stefan, Bernstein, Inge, Capellá, Gabriel, Engel, Christoph, Gomez-Garcia, Encarna B, van Hest, Liselot P, von Knebel Doeberitz, Magnus, Lagerstedt-Robinson, Kristina, Letteboer, Tom G W, Moller, Pal, van Os, Theo A, Pineda, Marta, Rahner, Nils, Olderode-Berends, Maran J W, von Salomé, Jenny, Schackert, Hans K, Spruijt, Liesbeth, Steinke-Lange, Verena, Wagner, Anja, Tops, Carli M J, Nielsen, Maartje

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Mutational Signature Analysis Reveals NTHL1 Deficiency to Cause a Multi-tumor Phenotype von Grolleman, Judith E., de Voer, Richarda M., Elsayed, Fadwa A., Nielsen, Maartje, Weren, Robbert D.A., Palles, Claire, Ligtenberg, Marjolijn J.L., Vos, Janet R., ten Broeke, Sanne W., de Miranda, Noel F.C.C., Kuiper, Renske A., Kamping, Eveline J., Jansen, Erik A.M., Vink-Börger, M. Elisa, Popp, Isabell, Lang, Alois, Spier, Isabel, Hüneburg, Robert, James, Paul A., Li, Na, Staninova, Marija, Lindsay, Helen, Cockburn, David, Spasic-Boskovic, Olivera, Clendenning, Mark, Sweet, Kevin, Capellá, Gabriel, Sjursen, Wenche, Høberg-Vetti, Hildegunn, Jongmans, Marjolijn C., Neveling, Kornelia, Geurts van Kessel, Ad, Morreau, Hans, Hes, Frederik J., Sijmons, Rolf H., Schackert, Hans K., Ruiz-Ponte, Clara, Dymerska, Dagmara, Lubinski, Jan, Rivera, Barbara, Foulkes, William D., Tomlinson, Ian P., Valle, Laura, Buchanan, Daniel. D., Kenwrick, Sue, Adlard, Julian, Dimovski, Aleksandar J., Campbell, Ian G., Aretz, Stefan, Schindler, Detlev, van Wezel, Tom, Hoogerbrugge, Nicoline, Kuiper, Roland P.

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Cancer risks by gene, age, and gender in 6350 carriers of pathogenic mismatch repair variants: findings from the Prospective Lynch Syndrome Database von Dominguez-Valentin, Mev, Sampson, Julian R., Seppälä, Toni T., ten Broeke, Sanne W., Plazzer, John-Paul, Nakken, Sigve, Engel, Christoph, Aretz, Stefan, Jenkins, Mark A., Sunde, Lone, Bernstein, Inge, Capella, Gabriel, Balaguer, Francesc, Thomas, Huw, Evans, D. Gareth, Burn, John, Greenblatt, Marc, Hovig, Eivind, de Vos tot Nederveen Cappel, Wouter H., Sijmons, Rolf H., Bertario, Lucio, Tibiletti, Maria Grazia, Cavestro, Giulia Martina, Lindblom, Annika, Della Valle, Adriana, Lopez-Köstner, Francisco, Gluck, Nathan, Katz, Lior H., Heinimann, Karl, Vaccaro, Carlos A., Büttner, Reinhard, Görgens, Heike, Holinski-Feder, Elke, Morak, Monika, Holzapfel, Stefanie, Hüneburg, Robert, Knebel Doeberitz, Magnus von, Loeffler, Markus, Rahner, Nils, Schackert, Hans K., Steinke-Lange, Verena, Schmiegel, Wolff, Vangala, Deepak, Pylvänäinen, Kirsi, Renkonen-Sinisalo, Laura, Hopper, John L., Win, Aung Ko, Haile, Robert W., Lindor, Noralane M., Gallinger, Steven, Le Marchand, Loïc, Newcomb, Polly A., Figueiredo, Jane C., Thibodeau, Stephen N., Wadt, Karin, Therkildsen, Christina, Okkels, Henrik, Ketabi, Zohreh, Moreira, Leticia, Sánchez, Ariadna, Serra-Burriel, Miquel, Pineda, Marta, Navarro, Matilde, Blanco, Ignacio, Green, Kate, Lalloo, Fiona, Crosbie, Emma J., Hill, James, Denton, Oliver G., Frayling, Ian M., Rødland, Einar Andreas, Vasen, Hans, Mints, Miriam, Neffa, Florencia, Esperon, Patricia, Alvarez, Karin, Kariv, Revital, Rosner, Guy, Pinero, Tamara Alejandra, Gonzalez, María Laura, Kalfayan, Pablo, Tjandra, Douglas, Winship, Ingrid M., Macrae, Finlay, Möslein, Gabriela, Mecklin, Jukka-Pekka, Nielsen, Maartje, Møller, Pål

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The effect of genotypes and parent of origin on cancer risk and age of cancer development in PMS2 mutation carriers von Suerink, Manon, van der Klift, Heleen M., ten Broeke, Sanne W., Dekkers, Olaf M., Bernstein, Inge, Capellá Munar, Gabriel, Gomez Garcia, Encarna, Hoogerbrugge, Nicoline, Letteboer, Tom G.W., Menko, Fred H., Lindblom, Annika, Mensenkamp, Arjen, Moller, Pal, van Os, Theo A., Rahner, Nils, Redeker, Bert J.W., Olderode, Maran, Spruijt, Liesbeth, Vos, Yvonne J., Wagner, Anja, Morreau, Hans, Hes, Frederik J., Vasen, Hans F.A., Tops, Carli M., Wijnen, Juul T., Nielsen, Maartje

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A Dutch MYH7 founder mutation, p.(Asn1918Lys), is associated with early onset cardiomyopathy and congenital heart defects von van der Linde, I. H. M., Hiemstra, Y. L., Bökenkamp, R., van Mil, A. M., Breuning, M. H., Ruivenkamp, C., ten Broeke, S. W., Veldkamp, R. F., van Waning, J. I., van Slegtenhorst, M. A., van Spaendonck-Zwarts, K. Y., Lekanne Deprez, R. H., Herkert, J. C., Boven, L., van der Zwaag, P. A., Jongbloed, J. D. H., Bootsma, M., Barge-Schaapveld, D. Q. C. M.

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Cancer Risks for PMS2-Associated Lynch Syndrome von Ten Broeke, Sanne W, van der Klift, Heleen M, Tops, Carli M J, Aretz, Stefan, Bernstein, Inge, Buchanan, Daniel D, de la Chapelle, Albert, Capella, Gabriel, Clendenning, Mark, Engel, Christoph, Gallinger, Steven, Gomez Garcia, Encarna, Figueiredo, Jane C, Haile, Robert, Hampel, Heather L, Hopper, John L, Hoogerbrugge, Nicoline, von Knebel Doeberitz, Magnus, Le Marchand, Loic, Letteboer, Tom G W, Jenkins, Mark A, Lindblom, Annika, Lindor, Noralane M, Mensenkamp, Arjen R, Møller, Pål, Newcomb, Polly A, van Os, Theo A M, Pearlman, Rachel, Pineda, Marta, Rahner, Nils, Redeker, Egbert J W, Olderode-Berends, Maran J W, Rosty, Christophe, Schackert, Hans K, Scott, Rodney, Senter, Leigha, Spruijt, Liesbeth, Steinke-Lange, Verena, Suerink, Manon, Thibodeau, Stephen, Vos, Yvonne J, Wagner, Anja, Winship, Ingrid, Hes, Frederik J, Vasen, Hans F A, Wijnen, Juul T, Nielsen, Maartje, Win, Aung Ko

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A PMS2-specific colorectal surveillance guideline von ten Broeke, Sanne W., Nielsen, Maartje

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Lynch syndrome caused by germline PMS2 mutations: delineating the cancer risk von ten Broeke, Sanne W, Brohet, Richard M, Tops, Carli M, van der Klift, Heleen M, Velthuizen, Mary E, Bernstein, Inge, Capellá Munar, Gabriel, Gomez Garcia, Encarna, Hoogerbrugge, Nicoline, Letteboer, Tom G W, Menko, Fred H, Lindblom, Annika, Mensenkamp, Arjen R, Moller, Pal, van Os, Theo A, Rahner, Nils, Redeker, Bert J W, Sijmons, Rolf H, Spruijt, Liesbeth, Suerink, Manon, Vos, Yvonne J, Wagner, Anja, Hes, Frederik J, Vasen, Hans F, Nielsen, Maartje, Wijnen, Juul T

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MLH1 Promotor Hypermethylation in Colorectal and Endometrial Carcinomas from Patients with Lynch Syndrome von Helderman, Noah C, Andini, Katarina D, van Leerdam, Monique E, van Hest, Liselotte P, Hoekman, Daniël R, Ahadova, Aysel, Bajwa-Ten Broeke, Sanne W, Bosse, Tjalling, van der Logt, Elise M J, Imhann, Floris, Kloor, Matthias, Langers, Alexandra M J, Smit, Vincent T H B M, Terlouw, Diantha, van Wezel, Tom, Morreau, Hans, Nielsen, Maartje

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