PBPK Models for CYP3A4 and P‐gp DDI Prediction: A Modeling Network of Rifampicin, Itraconazole, Clarithromycin, Midazolam, Alfentanil, and Digoxin von Hanke, Nina, Frechen, Sebastian, Moj, Daniel, Britz, Hannah, Eissing, Thomas, Wendl, Thomas, Lehr, Thorsten

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Data Digitizing: Accurate and Precise Data Extraction for Quantitative Systems Pharmacology and Physiologically‐Based Pharmacokinetic Modeling von Wojtyniak, Jan‐Georg, Britz, Hannah, Selzer, Dominik, Schwab, Matthias, Lehr, Thorsten

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A physiologically based pharmacokinetic and pharmacodynamic (PBPK/PD) model of the histone deacetylase (HDAC) inhibitor vorinostat for pediatric and adult patients and its applicat... von Moj, Daniel, Britz, Hannah, Burhenne, Jürgen, Stewart, Clinton F., Egerer, Gerlinde, Haefeli, Walter E., Lehr, Thorsten

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Physiologically‐Based Pharmacokinetic Models for CYP1A2 Drug–Drug Interaction Prediction: A Modeling Network of Fluvoxamine, Theophylline, Caffeine, Rifampicin, and Midazolam von Britz, Hannah, Hanke, Nina, Volz, Anke‐Katrin, Spigset, Olav, Schwab, Matthias, Eissing, Thomas, Wendl, Thomas, Frechen, Sebastian, Lehr, Thorsten

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Physiologically Based Pharmacokinetic Models of Probenecid and Furosemide to Predict Transporter Mediated Drug-Drug Interactions von Britz, Hannah, Hanke, Nina, Taub, Mitchell E., Wang, Ting, Prasad, Bhagwat, Fernandez, Éric, Stopfer, Peter, Nock, Valerie, Lehr, Thorsten

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Comprehensive Parent–Metabolite PBPK/PD Modeling Insights into Nicotine Replacement Therapy Strategies von Kovar, Lukas, Selzer, Dominik, Britz, Hannah, Benowitz, Neal, St. Helen, Gideon, Kohl, Yvonne, Bals, Robert, Lehr, Thorsten

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Clarithromycin, Midazolam, and Digoxin: Application of PBPK Modeling to Gain New Insights into Drug–Drug Interactions and Co-medication Regimens von Moj, Daniel, Hanke, Nina, Britz, Hannah, Frechen, Sebastian, Kanacher, Tobias, Wendl, Thomas, Haefeli, Walter Emil, Lehr, Thorsten

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A physiologically based pharmacokinetic (PBPK) parent-metabolite model of the chemotherapeutic zoptarelin doxorubicin—integration of in vitro results, Phase I and Phase II data and... von Hanke, Nina, Teifel, Michael, Moj, Daniel, Wojtyniak, Jan-Georg, Britz, Hannah, Aicher, Babette, Sindermann, Herbert, Ammer, Nicola, Lehr, Thorsten

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Physiologically‐Based Pharmacokinetic Models for CYP 1A2 Drug–Drug Interaction Prediction: A Modeling Network of Fluvoxamine, Theophylline, Caffeine, Rifampicin, and Midazolam von Britz, Hannah, Hanke, Nina, Volz, Anke‐Katrin, Spigset, Olav, Schwab, Matthias, Eissing, Thomas, Wendl, Thomas, Frechen, Sebastian, Lehr, Thorsten

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Comprehensive Parent-Metabolite PBPK/PD Modeling Insights into Nicotine Replacement Therapy Strategies von Kovar, Lukas, Selzer, Dominik, Britz, Hannah, Benowitz, Neal, Helen, Gideon S, Kohl, Yvonne, Bals, Robert, Lehr, Thorsten

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Physiologically-based pharmacokinetic models for CYP1A2 drug-drug interaction prediction: A modeling network of fluvoxamine, theophylline, caffeine, rifampicin, and midazolam von Britz, Hannah, Hanke, Nina, Volz, Anke-Katrin, Spigset, Olav, Schwab, Matthias, Eissing, Thomas, Wendl, Thomas, Frechen, Sebastian, Lehr, Thorsten

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Primary care provider availability and economic and racial residential segregation von Shadowen, Hannah, Krist, Alex, Sabo, Roy, Britz, Jacqueline

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Abstract WP84: Optimizing Longitudinal Follow Up For Outcomes Research Among Patients With Intracerebral Hemorrhage von Kelly, Hannah, Johnson, Carnayla, Baig, Eman, Jefferson, Imory, Adegbindin, Sofiat, Khan, Osman, Nair, Rejani R, Britz, Gavin W, Vahidy, Farhaan, Tannous, Jonika

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A Neuro-Informatics Pipeline for Cerebrovascular Disease: Research Registry Development von Potter, Thomas B H, Pratap, Sharmila, Nicolas, Juan Carlos, Khan, Osman S, Pan, Alan P, Bako, Abdulaziz T, Hsu, Enshuo, Johnson, Carnayla, Jefferson, Imory N, Adegbindin, Sofiat K, Baig, Eman, Kelly, Hannah R, Jones, Stephen L, Britz, Gavin W, Tannous, Jonika, Vahidy, Farhaan S

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Abstract TMP51: A Big-data Neuro-informatics Infrastructure To Support Research Pipelines For Cerebrovascular Disease von Potter, Thomas B, Pratap, Sharmila, Nicolas, Charlie, Khan, Osman, Pan, Alan P, Bako, Abdulaziz, Hsu, Enshuo, Johnson, Carnayla, Baig, Eman, Kelly, Hannah, Jones, Stephen, Britz, Gavin W, Tannous, Jonika, Vahidy, Farhaan

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Stroke severity mediates the effect of socioeconomic disadvantage on poor outcomes among patients with intracerebral hemorrhage von Potter, Thomas B H, Tannous, Jonika, Pan, Alan P, Bako, Abdulaziz, Johnson, Carnayla, Baig, Eman, Kelly, Hannah, McCane, Charles D, Garg, Tanu, Gadhia, Rajan, Misra, Vivek, Volpi, John, Britz, Gavin, Chiu, David, Vahidy, Farhaan S

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Abstract WP129: Sociodemographic, Clinical, And Outcomes Characteristics Of Young Adult Patients With Intracerebral Hemorrhage von Johnson, Carnayla, Kelly, Hannah, Baig, Eman, Jefferson, Imory, Adegbindin, Sofiat, Potter, Thomas, Bako, Abdulaziz, Pan, Alan P, Khan, Osman, Nair, Rejani R, McCane, Charles D, Garg, Tanu, Misra, Vivek, Gadhia, Rajan, Volpi, John J, Chiu, David, Britz, Gavin W, Vahidy, Farhaan, Tannous, Jonika

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Parry-Romberg Syndrome and an Associated Complex Vascular Lesion Managed With Hybrid Strategies: A Case Report von Hagstrom, Rory, Riina, Howard A., Britz, Gavin W., Sharashidze, Vera, Chung, Charlotte, Weiss, Hannah, Spetzler, Robert F., Nelson, Peter Kim

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The interplay of viral loads, clinical presentation, and serological responses in SARS-CoV-2 – Results from a prospective cohort of outpatient COVID-19 cases von Castelletti, Noemi, Rubio-Acero, Raquel, Geldmacher, Christof, Eser, Tabea M., Deák, Flora, Paunovic, Ivana, Bakuli, Abhishek, Saathoff, Elmar, von Meyer, Alexander, Falk, Philine, Reich, Jakob, Riess, Friedrich, Girl, Philipp, Müller, Katharina, Radon, Katja, Guggenbuehl Noller, Jessica Michelle, Wölfel, Roman, Hoelscher, Michael, Kroidl, Inge, Wieser, Andreas, Alamoudi, Emad, Anderson, Jared, Baumann, Maximilian, Behlen, Marieke, Beyerl, Jessica, Böhnlein, Rebecca, Britz, Vera, Bruger, Jan, Caroli, Friedrich, Contento, Lorenzo, Do, Anna, Eberle, Ute, Eckstein, Judith, Frese, Jonathan, Forster, Felix, Frahnow, Turid, Fröschl, Günter, Geisenberger, Otto, Gillig, Kristina, Hoefflin, Janna, Hofberger, Tim, Höfinger, Michael, Hofmann, Larissa, Horn, Sacha, Huber, Kristina, Janke, Christian, Kappl, Ursula, Kiani, Charlotte, Kroidl, Arne, Leidl, Reiner, Lindner, Felix, Mayrhofer, Rebecca, Mekota, Anna-Maria, Müller, Hannah, Metaxa, Dafni, Pattard, Leonie, Pletschette, Michel, Prückner, Stephan, Pusl, Konstantin, Rothe, Camila, Schäfer, Nicole, Schandelmaier, Paul, Schultz, Sophie, Schwettmann, Lars, Seibold, Heidi, Sothmann, Peter, Stapor, Paul, Theis, Fabian, Thiel, Verena, Thiesbrummel, Sophie, Thur, Niklas, Waibel, Julia, Winter, Simon, Wolff, Julia, Wullinger, Pia, Yaqine, Houda, Zange, Sabine, Zeggini, Eleftheria, Zimmermann, Thomas, Zielke, Anna, Ibraheem, Mohamed, Ahmed, Mohamed, Becker, Marc, Diepers, Paulina, Schälte, Yannik, Garí, Mercè, Pütz, Peter, Pritsch, Michael, Fingerle, Volker, Brand, Isabel, Eser, Tabea, Weinauer, Franz, Martin, Silke, Quenzel, Ernst-Markus, Durner, Jürgen, Girl, Philipp, Müller, Katharina, Radon, Katja, Fuchs, Christiane, Hasenauer, Jan

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