Cellular and complement-dependent cytotoxicity of Ep-CAM-specific monoclonal antibody MT201 against breast cancer cell lines von Prang, N, Preithner, S, Brischwein, K, Göster, P, Wöppel, A, Müller, J, Steiger, C, Peters, M, Baeuerle, P A, da Silva, A J

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Serial killing of tumor cells by cytotoxic T cells redirected with a CD19‐/CD3‐bispecific single‐chain antibody construct von Hoffmann, Patrick, Hofmeister, Robert, Brischwein, Klaus, Brandl, Christian, Crommer, Sandrine, Bargou, Ralf, Itin, Christian, Prang, Nadja, Baeuerle, Patrick A.

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Strictly Target Cell-dependent Activation of T Cells by Bispecific Single-chain Antibody Constructs of the BiTE Class von BRISCHWEIN, Klaus, PARR, Larissa, SCHLERETH, Bernd, BAEUERLE, Patrick A, PFLANZ, Stefan, VOLKLAND, Jörg, LUMSDEN, John, KLINGER, Matthias, LOCHER, Mathias, HAMMOND, Scott A, KIENER, Peter, KUFER, Peter

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MT110: A novel bispecific single-chain antibody construct with high efficacy in eradicating established tumors von Brischwein, Klaus, Schlereth, Bernd, Guller, Benjamin, Steiger, Carola, Wolf, Andreas, Lutterbuese, Ralf, Offner, Sonja, Locher, Mathias, Urbig, Thomas, Raum, Tobias, Kleindienst, Petra, Wimberger, Pauline, Kimmig, Rainer, Fichtner, Iduna, Kufer, Peter, Hofmeister, Robert, da Silva, Antonio J., Baeuerle, Patrick A.

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Eradication of tumors from a human colon cancer cell line and from ovarian cancer metastases in immunodeficient mice by a single-chain Ep-CAM-/CD3-bispecific antibody construct von SCHLERETH, Bernd, FICHTNER, Iduna, WIMBERGER, Pauline, KIMMIG, Rainer, BAEUERLE, Patrick A, LORENCZEWSKI, Grit, KLEINDIENST, Petra, BRISCHWEIN, Klaus, DA SILVA, Antonio, KUFER, Peter, LUTTERBUESE, Ralf, JUNGHAHN, Ilse, KASIMIR-BAUER, Sabine

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Antitumor Activity of an EpCAM/CD3-bispecific BiTE Antibody During Long-term Treatment of Mice in the Absence of T-cell Anergy and Sustained Cytokine Release von AMANN, Maria, DARGOUGES, Sandrine, RAUM, Tobias, MÜNZ, Markus, KUFER, Peter, SCHLERETH, Bernd, BAEUERLE, Patrick A, FRIEDRICH, Matthias, LORENCZEWSKI, Grit, BRISCHWEIN, Klaus, KISCHEL, Roman, LUTTERBUESE, Ralf, MANGOLD, Susanne, RAY, Doris, VOLKLAND, Jörg, PFLANZ, Stefan

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Potent inhibition of local and disseminated tumor growth in immunocompetent mouse models by a bispecific antibody construct specific for Murine CD3 von SCHLERETH, Bernd, KLEINDIENST, Petra, KUFER, Peter, BAEUERLE, Patrick A, FICHTNER, Iduna, LORENCZEWSKI, Grit, BRISCHWEIN, Klaus, LIPPOLD, Sandra, DA SILVA, Antonio, LOCHER, Mathias, KISCHEL, Roman, LUTTERBIISE, Ralf

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Down-regulation of protein kinase Cη by antisense oligonucleotides sensitises A549 lung cancer cells to vincristine and paclitaxel von Sonnemann, Jürgen, Gekeler, Volker, Ahlbrecht, Katrin, Brischwein, Klaus, Liu, Chao, Bader, Peter, Müller, Cornelia, Niethammer, Dietrich, Beck, James F

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Anticancer Drug‐mediated Induction of Multidrug Resistance‐associated Genes and Protein Kinase C Isozymes in the T‐Lymphoblastoid Cell Line CCRF‐CEM and in Blasts from Patients wit... von Beck, James F., Brügger, Dorothee, Brischwein, Klaus, Liu, Chao, Bader, Peter, Niethammer, Dietrich, Gekeler, Volker

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200 POSTER Strictly target cell-dependent activation of T cells by bispecific single-chain antibody constructs of the BITE class von Brischwein, K., Parr, L., Pflanz, S., Volkland, J., Lumsden, J., Klinger, M., Schlereth, B., Locher, M., Kufer, P., Baeuerle, P.A.

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224 POSTER Characterization of a murine EpCAM/CD3-bispecific BiTE molecule as a surrogate for preclinical development of the human EpCAM/CD3-bispecific BiTE molecule MT110 von Schlereth, B., Brischwein, K., Lutterbuese, P., Parr, L., Lorenczewski, G., Aman, M., Kischel, R., Kufer, P., Locher, M., Baeuerle, P.A.

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Role of Ribonucleotide Reductase and Deoxynucleotide Pools in the Oxygen‐Dependent Control of DNA Replication in Ehrlich Ascites Cells von Brischwein, Klaus, Engelcke, Michael, Riedinger, Hans‐Jörg, Probst, Hans

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Staurosporine suppresses replicon initiation in mammalian cells von Gekeler, Volker, Wilisch, Annette, Probst, Gudrun, Kugel, Andrea, Brischwein, Klaus, Engelcke, Michael, Probst, Hans

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Ex vivo Therapie maligner Pleuraergüsse beim metastasierten Mammakarzinom mit dem bispezifischen anti EpCAM/CD3 Antikörper MT110 von Witthauer, Juliane, Schlereth, B., Brischwein, K., Funke, I., Jauch, K. -W., Baeuerle, P., Mayer, Barbara

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Smartphone-based colorimetric detection system for portable health tracking von Balbach, Samira, Jiang, Nan, Moreddu, Rosalia, Dong, Xingchen, Kurz, Wolfgang, Wang, Congyan, Dong, Jie, Yin, Yixia, Butt, Haider, Brischwein, Martin, Hayden, Oliver, Jakobi, Martin, Tasoglu, Savas, Koch, Alexander W, Yetisen, Ali K

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Scleral Lens Sensor for Ocular Electrolyte Analysis von Yetisen, Ali K., Jiang, Nan, Castaneda Gonzalez, Carmen M., Erenoglu, Zeynep Izlen, Dong, Jie, Dong, Xingchen, Stößer, Simon, Brischwein, Martin, Butt, Haider, Cordeiro, Maria F., Jakobi, Martin, Hayden, Oliver, Koch, Alexander W.

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Scleral lens sensor for ocular electrolyte analysis von Yetisen, AK, Jiang, N, Castaneda Gonzalez, CM, Erenoglu, ZI, Dong, J, Dong, X, Stößer, S, Brischwein, M, Butt, H, Cordeiro, MF, Jakobi, M, Hayden, O, Koch, AW

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Monitoring of cellular behaviour by impedance measurements on interdigitated electrode structures von Ehret, R., Baumann, W., Brischwein, M., Schwinde, A., Stegbauer, K., Wolf, B.

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Smartphone-based colorimetric detection system for portable health tracking von Balbach, S, Jiang, N, Moreddu, R, Dong, X, Kurz, W, Wang, C, Dong, J, Yin, Y, Butt, H, Brischwein, M, Hayden, O, Jakobi, M, Tasoglu, S, Koch, A, Yetisen, AK

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