Evaluation of drug‐induced QT interval prolongation in animal and human studies: a literature review of concordance von Vargas, Hugo M, Bass, Alan S, Koerner, John, Matis‐Mitchell, Sherri, Pugsley, Michael K, Skinner, Matthew, Burnham, Matthew, Bridgland‐Taylor, Matthew, Pettit, Syril, Valentin, Jean‐Pierre

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Prediction of Thorough QT study results using action potential simulations based on ion channel screens von Mirams, Gary R., Davies, Mark R., Brough, Stephen J., Bridgland-Taylor, Matthew H., Cui, Yi, Gavaghan, David J., Abi-Gerges, Najah

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A correlation between the in vitro drug toxicity of drugs to cell lines that express human P450s and their propensity to cause liver injury in humans von Gustafsson, Frida, Foster, Alison J, Sarda, Sunil, Bridgland-Taylor, Matthew H, Kenna, J Gerry

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A New Perspective in the Field of Cardiac Safety Testing through the Comprehensive In Vitro Proarrhythmia Assay Paradigm von Fermini, Bernard, Hancox, Jules C., Abi-Gerges, Najah, Bridgland-Taylor, Matthew, Chaudhary, Khuram W., Colatsky, Thomas, Correll, Krystle, Crumb, William, Damiano, Bruce, Erdemli, Gul, Gintant, Gary, Imredy, John, Koerner, John, Kramer, James, Levesque, Paul, Li, Zhihua, Lindqvist, Anders, Obejero-Paz, Carlos A., Rampe, David, Sawada, Kohei, Strauss, David G., Vandenberg, Jamie I.

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Prospective Prediction of Antitarget Activity by Matched Molecular Pairs Analysis von Warner, Daniel J., Bridgland-Taylor, Matthew H., Sefton, Clare E., Wood, David J.

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Mutations of the nACh Receptor M4 Helix Reveal Different Phenotypes in Different Expression Systems: Could Lipids be Responsible? von Mesoy, Susanne M, Bridgland-Taylor, Matthew, Lummis, Sarah C R

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Translational understanding of PDE4 inhibition von Larner, Carrie, Bridgland-Taylor, Matthew, Collins, Robert, Larsson, Marie, Bird, James, Rolf, Mike

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Cross-site and cross-platform variability of automated patch clamp assessments of drug effects on human cardiac currents in recombinant cells von Kramer, James, Himmel, Herbert M., Lindqvist, Anders, Stoelzle-Feix, Sonja, Chaudhary, Khuram W., Li, Dingzhou, Bohme, Georg Andrees, Bridgland-Taylor, Matthew, Hebeisen, Simon, Fan, Jingsong, Renganathan, Muthukrishnan, Imredy, John, Humphries, Edward S. A., Brinkwirth, Nina, Strassmaier, Tim, Ohtsuki, Atsushi, Danker, Timm, Vanoye, Carlos, Polonchuk, Liudmila, Fermini, Bernard, Pierson, Jennifer Beck, Gintant, Gary

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A systematic strategy for estimating hERG block potency and its implications in a new cardiac safety paradigm von Ridder, Bradley J., Leishman, Derek J., Bridgland-Taylor, Matthew, Samieegohar, Mohammadreza, Han, Xiaomei, Wu, Wendy W., Randolph, Aaron, Tran, Phu, Sheng, Jiansong, Danker, Timm, Lindqvist, Anders, Konrad, Daniel, Hebeisen, Simon, Polonchuk, Liudmila, Gissinger, Evgenia, Renganathan, Muthukrishnan, Koci, Bryan, Wei, Haiyang, Fan, Jingsong, Levesque, Paul, Kwagh, Jae, Imredy, John, Zhai, Jin, Rogers, Marc, Humphries, Edward, Kirby, Robert, Stoelzle-Feix, Sonja, Brinkwirth, Nina, Rotordam, Maria Giustina, Becker, Nadine, Friis, Søren, Rapedius, Markus, Goetze, Tom A., Strassmaier, Tim, Okeyo, George, Kramer, James, Kuryshev, Yuri, Wu, Caiyun, Himmel, Herbert, Mirams, Gary R., Strauss, David G., Bardenet, Rémi, Li, Zhihua

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Effect of mutating amino acids considered critical for hERG channel blocker activity on the profile of a hERG channel activator von Mannikko, Roope, Bridgland-Taylor, Matthew, Pollard, Chris

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Corrigendum to “A systematic strategy for estimating hERG block potency and its implications in a new cardiac safety paradigm” [Toxicology and Applied Pharmacology volume 394C (202... von Ridder, Bradley J., Leishman, Derek J., Bridgland-Taylor, Matthew, Samieegohar, Mohammadreza, Han, Xiaomei, Wu, Wendy W., Randolph, Aaron, Tran, Phu, Sheng, Jiansong, Danker, Timm, Lindqvist, Anders, Konrad, Daniel, Hebeisen, Simon, Polonchuk, Liudmila, Gissinger, Evgenia, Renganathan, Muthukrishnan, Koci, Bryan, Wei, Haiyang, Fan, Jingsong, Levesque, Paul, Kwagh, Jae, Imredy, John, Zhai, Jin, Rogers, Marc, Humphries, Edward, Kirby, Robert, Stoelzle-Feix, Sonja, Brinkwirth, Nina, Rotordam, Maria Giustina, Becker, Nadine, Friis, Søren, Rapedius, Markus, Goetze, Tom A., Strassmaier, Tim, Okeyo, George, Kramer, James, Kuryshev, Yuri, Wu, Caiyun, Himmel, Herbert, Mirams, Gary R., Strauss, David G., Bardenet, Remi, Li, Zhihua

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Publisher Correction: Cross-site and cross-platform variability of automated patch clamp assessments of drug effects on human cardiac currents in recombinant cells von Kramer, James, Himmel, Herbert M., Lindqvist, Anders, Stoelzle-Feix, Sonja, Chaudhary, Khuram W., Li, Dingzhou, Bohme, Georg Andrees, Bridgland-Taylor, Matthew, Hebeisen, Simon, Fan, Jingsong, Renganathan, Muthukrishnan, Imredy, John, Humphries, Edward S. A., Brinkwirth, Nina, Strassmaier, Tim, Ohtsuki, Atsushi, Danker, Timm, Vanoye, Carlos, Polonchuk, Liudmila, Fermini, Bernard, Pierson, Jennifer Beck, Gintant, Gary

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Mechanistic investigation into a delayed onset QTc prolongation von Gray, Kelly, Pointon, Amy, Rose, Alexandra, Philp, Karen, Moors, Jackie, Skinner, Matthew, Bridgland-Taylor, Matthew, Harmer, Alex

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Prediction and Modeling of Effects on the QTc Interval for Clinical Safety Margin Assessment, Based on Single-Ascending-Dose Study Data with AZD3839 von Sparve, Erik, Quartino, Angelica L., Lüttgen, Maria, Tunblad, Karin, Gårdlund, Anna Teiling, Fälting, Johanna, Alexander, Robert, Kågström, Jens, Sjödin, Linnea, Bulgak, Alexander, Al-Saffar, Ahmad, Bridgland-Taylor, Matthew, Pollard, Chris, Swedberg, Michael D.B., Vik, Torbjörn, Paulsson, Björn

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Cardiac contractility assessment: A case study with clear impact and relevance of preclinical data von Lainée, Pierre, Philp, Karen, Harmer, Alex, Bridgland-Taylor, Matthew, Moors, Jackie, Knight, Richard, Valentin, Jean-Pierre

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Validation of a cardiac L-type calcium channel assay using IonWorks von Dilbaghi, Sahiba, Abi-Gerges, Najah, Morton, Micheal J., Bridgland-Taylor, Matthew H., Pollard, Chris E., Valentin, Jean-Pierre

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Validation of a voltage-sensitive dye (di-4-ANEPPS)-based method for assessing drug-induced delayed repolarisation in Beagle dog left ventricular midmyocardial myocytes von Hardy, Matthew E.L., Pollard, Chris E., Small, Ben G., Bridgland-Taylor, Matthew, Woods, Ann J., Valentin, Jean-Pierre, Abi-Gerges, Najah

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Mutations of the nACh Receptor M4 Helix Reveal Different Phenotypes in Different Expression Systems: Could Lipids be Responsible? von Mesoy, Susanne M, Bridgland-Taylor, Matthew, Lummis, Sarah CR

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