What genetics tells us about the causes and mechanisms of Parkinson's disease von Corti, Olga, Lesage, Suzanne, Brice, Alexis

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Loss of function of C9orf72 causes motor deficits in a zebrafish model of amyotrophic lateral sclerosis von Ciura, Sorana, Lattante, Serena, Le Ber, Isabelle, Latouche, Morwena, Tostivint, Hervé, Brice, Alexis, Kabashi, Edor

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Plasma neurofilament light chain predicts cerebellar atrophy and clinical progression in spinocerebellar ataxia von Coarelli, Giulia, Darios, Frederic, Petit, Emilien, Dorgham, Karim, Adanyeguh, Isaac, Petit, Elodie, Brice, Alexis, Mochel, Fanny, Durr, Alexandra

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Functional interplay between Parkin and Drp1 in mitochondrial fission and clearance von Buhlman, Lori, Damiano, Maria, Bertolin, Giulia, Ferrando-Miguel, Rosa, Lombès, Anne, Brice, Alexis, Corti, Olga

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Parkin deficiency modulates NLRP3 inflammasome activation by attenuating an A20‐dependent negative feedback loop von Mouton‐Liger, François, Rosazza, Thibault, Sepulveda‐Diaz, Julia, Ieang, Amélie, Hassoun, Sidi‐Mohamed, Claire, Emilie, Mangone, Graziella, Brice, Alexis, Michel, Patrick P., Corvol, Jean‐Christophe, Corti, Olga

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Loss of spatacsin function alters lysosomal lipid clearance leading to upper and lower motor neuron degeneration von Branchu, Julien, Boutry, Maxime, Sourd, Laura, Depp, Marine, Leone, Céline, Corriger, Alexandrine, Vallucci, Maeva, Esteves, Typhaine, Matusiak, Raphaël, Dumont, Magali, Muriel, Marie-Paule, Santorelli, Filippo M, Brice, Alexis, El Hachimi, Khalid Hamid, Stevanin, Giovanni, Darios, Frédéric

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Monogenic PD in Brazil: a step towards precision medicine von Courtin, Thomas, Brice, Alexis

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A mitochondrial origin for frontotemporal dementia and amyotrophic lateral sclerosis through CHCHD10 involvement von BANNWARTH, Sylvie, AIT-EL-MKADEM, Samira, VERSCHUEREN, Annie, ROUZIER, Cecile, LE BER, Isabelle, AUGE, Gaëlle, COCHAUD, Charlotte, LESPINASSE, Françoise, N'GUYEN, Karine, DE SEPTENVILLE, Anne, BRICE, Alexis, YU-WAI-MAN, Patrick, CHAUSSENOT, Annabelle, SESAKI, Hiromi, POUGET, Jean, PAQUIS-FLUCKLINGER, Véronique, GENIN, Emmanuelle C, LACAS-GERVAIS, Sandra, FRAGAKI, Konstantina, BERG-ALONSO, Laetitia, KAGEYAMA, Yusuke, SERRE, Valérie, MOORE, David G

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DNA repair pathways underlie a common genetic mechanism modulating onset in polyglutamine diseases von Bettencourt, Conceição, Hensman-Moss, Davina, Flower, Michael, Wiethoff, Sarah, Brice, Alexis, Goizet, Cyril, Stevanin, Giovanni, Koutsis, Georgios, Karadima, Georgia, Panas, Marios, Yescas-Gómez, Petra, García-Velázquez, Lizbeth Esmeralda, Alonso-Vilatela, María Elisa, Lima, Manuela, Raposo, Mafalda, Traynor, Bryan, Sweeney, Mary, Wood, Nicholas, Giunti, Paola, Durr, Alexandra, Holmans, Peter, Houlden, Henry, Tabrizi, Sarah J., Jones, Lesley

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A Meta-Analysis of α-Synuclein Multiplication in Familial Parkinsonism von Book, Adam, Guella, Ilaria, Candido, Tara, Brice, Alexis, Hattori, Nobutaka, Jeon, Beomseok, Farrer, Matthew J

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Deregulation of autophagy in postmortem brains of Machado‐Joseph disease patients von Sittler, Annie, Muriel, Marie‐Paule, Marinello, Martina, Brice, Alexis, den Dunnen, Wilfred, Alves, Sandro

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Genetics of Parkinson's disease: LRRK2 on the rise von Brice, Alexis

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A deleterious mutation in DNAJC6 encoding the neuronal-specific clathrin-uncoating co-chaperone auxilin, is associated with juvenile parkinsonism von Edvardson, Simon, Cinnamon, Yuval, Ta-Shma, Asaf, Shaag, Avraham, Yim, Yang-In, Zenvirt, Shamir, Jalas, Chaim, Lesage, Suzanne, Brice, Alexis, Taraboulos, Albert, Kaestner, Klaus H, Greene, Lois E, Elpeleg, Orly

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Analysis of blood-based gene expression in idiopathic Parkinson disease von Shamir, Ron, Amar, David

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Penetrance estimate of LRRK2 p.G2019S mutation in individuals of non‐Ashkenazi Jewish ancestry von Lee, Annie J., Wang, Yuanjia, Alcalay, Roy N., Mejia‐Santana, Helen, Saunders‐Pullman, Rachel, Bressman, Susan, Corvol, Jean‐Christophe, Brice, Alexis, Lesage, Suzanne, Mangone, Graziella, Tolosa, Eduardo, Pont‐Sunyer, Claustre, Vilas, Dolores, Schüle, Birgitt, Kausar, Farah, Foroud, Tatiana, Berg, Daniela, Brockmann, Kathrin, Goldwurm, Stefano, Siri, Chiara, Asselta, Rosanna, Ruiz‐Martinez, Javier, Mondragón, Elisabet, Marras, Connie, Ghate, Taneera, Giladi, Nir, Mirelman, Anat, Marder, Karen

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Long-term disease progression in spinocerebellar ataxia types 1, 2, 3, and 6: a longitudinal cohort study von Jacobi, Heike, MD, du Montcel, Sophie Tezenas, PhD, Bauer, Peter, MD, Giunti, Paola, PhD, Cook, Arron, MBBS, Labrum, Robyn, MD, Parkinson, Michael H, MBBS, Durr, Alexandra, PhD, Brice, Alexis, Prof, Charles, Perrine, MD, Marelli, Cecilia, MD, Mariotti, Caterina, MD, Nanetti, Lorenzo, MD, Panzeri, Marta, MD, Rakowicz, Maria, MD, Sulek, Anna, PhD, Sobanska, Anna, MD, Schmitz-Hübsch, Tanja, MD, Schöls, Ludger, MD, Hengel, Holger, MD, Baliko, Laszlo, MD, Melegh, Bela, Prof, Filla, Alessandro, Prof, Antenora, Antonella, MD, Infante, Jon, MD, Berciano, José, Prof, van de Warrenburg, Bart P, PhD, Timmann, Dagmar, MD, Szymanski, Sandra, MD, Boesch, Sylvia, MD, Kang, Jun-Suk, MD, Pandolfo, Massimo, Prof, Schulz, Jörg B, Prof, Molho, Sonia, MSc, Diallo, Alhassane, MD, Klockgether, Thomas, Prof

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Recent advances in understanding dominant spinocerebellar ataxias from clinical and genetic points of view [version 1; peer review: 3 approved] von Coarelli, Giulia, Brice, Alexis, Durr, Alexandra

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Parkinson's disease patients show reduced cortical-subcortical sensorimotor connectivity von Sharman, Michael, Valabregue, Romain, Perlbarg, Vincent, Marrakchi-Kacem, Linda, Vidailhet, Marie, Benali, Habib, Brice, Alexis, Lehéricy, Stephane

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Propensity for somatic expansion increases over the course of life in Huntington disease von Kacher, Radhia, Lejeune, Francois-Xavier, Noel, Sandrine, Cazeneuve, Cecile, Brice, Alexis, Humbert, Sandrine, Durr, Alexandra

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Genetic characteristics of leucine-rich repeat kinase 2 ( LRRK2 ) associated Parkinson’s disease von Bardien, Soraya, Lesage, Suzanne, Brice, Alexis, Carr, Jonathan

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