Downstream processing of monoclonal antibodies—Application of platform approaches von Shukla, Abhinav A., Hubbard, Brian, Tressel, Tim, Guhan, Sam, Low, Duncan

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Large-scale chemical–genetics yields new M. tuberculosis inhibitor classes von Johnson, Eachan O., LaVerriere, Emily, Office, Emma, Stanley, Mary, Meyer, Elisabeth, Kawate, Tomohiko, Gomez, James E., Audette, Rebecca E., Bandyopadhyay, Nirmalya, Betancourt, Natalia, Delano, Kayla, Da Silva, Israel, Davis, Joshua, Gallo, Christina, Gardner, Michelle, Golas, Aaron J., Guinn, Kristine M., Kennedy, Sofia, Korn, Rebecca, McConnell, Jennifer A., Moss, Caitlin E., Murphy, Kenan C., Nietupski, Raymond M., Papavinasasundaram, Kadamba G., Pinkham, Jessica T., Pino, Paula A., Proulx, Megan K., Ruecker, Nadine, Song, Naomi, Thompson, Matthew, Trujillo, Carolina, Wakabayashi, Shoko, Wallach, Joshua B., Watson, Christopher, Ioerger, Thomas R., Lander, Eric S., Hubbard, Brian K., Serrano-Wu, Michael H., Ehrt, Sabine, Fitzgerald, Michael, Rubin, Eric J., Sassetti, Christopher M., Schnappinger, Dirk, Hung, Deborah T.

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Vancomycin Assembly: Nature's Way von Hubbard, Brian K., Walsh, Christopher T.

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Dissociation of Hepatic Steatosis and Insulin Resistance in Mice Overexpressing DGAT in the Liver von Monetti, Mara, Levin, Malin C., Watt, Matthew J., Sajan, Mini P., Marmor, Stephen, Hubbard, Brian K., Stevens, Robert D., Bain, James R., Newgard, Christopher B., Farese, Robert V., Hevener, Andrea L., Farese, Robert V.

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Monocyte tissue factor-dependent activation of coagulation in hypercholesterolemic mice and monkeys is inhibited by simvastatin von Owens, 3rd, A Phillip, Passam, Freda H, Antoniak, Silvio, Marshall, Stephanie M, McDaniel, Allison L, Rudel, Lawrence, Williams, Julie C, Hubbard, Brian K, Dutton, Julie-Ann, Wang, Jianguo, Tobias, Peter S, Curtiss, Linda K, Daugherty, Alan, Kirchhofer, Daniel, Luyendyk, James P, Moriarty, Patrick M, Nagarajan, Shanmugam, Furie, Barbara C, Furie, Bruce, Johns, Douglas G, Temel, Ryan E, Mackman, Nigel

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Mechanistic implications for LDL receptor degradation from the PCSK9/LDLR structure at neutral pH von Surdo, Paola Lo, Bottomley, Matthew J, Calzetta, Alessandra, Settembre, Ethan C, Cirillo, Agostino, Pandit, Shilpa, Ni, Yan G, Hubbard, Brian, Sitlani, Ayesha, Carfí, Andrea

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A Maltose-Binding Protein Fusion Construct Yields a Robust Crystallography Platform for MCL1 von Clifton, Matthew C, Dranow, David M, Leed, Alison, Fulroth, Ben, Fairman, James W, Abendroth, Jan, Atkins, Kateri A, Wallace, Ellen, Fan, Dazhong, Xu, Guoping, Ni, Z J, Daniels, Doug, Van Drie, John, Wei, Guo, Burgin, Alex B, Golub, Todd R, Hubbard, Brian K, Serrano-Wu, Michael H

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A Synergistic Nano‐Zerovalent Iron‐Hydrogen Peroxide Technology for Insensitive Munitions Wastewater Treatment von Elijah Akanbi, Oluwasegun, Kim, Inyoung, Cha, Daniel K., Attavane, Adithya A., Hubbard, Brian P., Chiu, Pei C.

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Allosteric MAPKAPK2 inhibitors improve plaque stability in advanced atherosclerosis von Ozcan, Lale, Kasikara, Canan, Yurdagul, Jr, Arif, Kuriakose, George, Hubbard, Brian, Serrano-Wu, Michael H, Tabas, Ira

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Anacetrapib promotes reverse cholesterol transport and bulk cholesterol excretion in Syrian golden hamsters von Castro-Perez, Jose, Briand, François, Gagen, Karen, Wang, Sheng-Ping, Chen, Ying, McLaren, David G., Shah, Vinit, Vreeken, Rob J., Hankemeier, Thomas, Sulpice, Thierry, Roddy, Thomas P., Hubbard, Brian K., Johns, Douglas G.

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Plasma lipid profiling across species for the identification of optimal animal models of human dyslipidemia[S] von Yin, Wu, Carballo-Jane, Ester, McLaren, David G., Mendoza, Vivienne H., Gagen, Karen, Geoghagen, Neil S., McNamara, Lesley Ann, Gorski, Judith N., Eiermann, George J., Petrov, Aleksandr, Wolff, Michael, Tong, Xinchun, Wilsie, Larissa C., Akiyama, Taro E., Chen, Jing, Thankappan, Anil, Xue, Jiyan, Ping, Xiaoli, Andrews, Genevieve, Wickham, L. Alexandra, Gai, Cesaire L., Trinh, Tu, Kulick, Alison A., Donnelly, Marcie J., Voronin, Gregory O., Rosa, Ray, Cumiskey, Anne-Marie, Bekkari, Kavitha, Mitnaul, Lyndon J., Puig, Oscar, Chen, Fabian, Raubertas, Richard, Wong, Peggy H., Hansen, Barbara C., Koblan, Ken S., Roddy, Thomas P., Hubbard, Brian K, Strack, Alison M.

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Deficiency of the intestinal enzyme acyl CoA:monoacylglycerol acyltransferase-2 protects mice from metabolic disorders induced by high-fat feeding von Yen, Chi-Liang Eric, Cheong, Mei-Leng, Grueter, Carrie, Zhou, Ping, Moriwaki, Junya, Wong, Jinny S, Hubbard, Brian, Marmor, Stephen, Farese, Robert V

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PCSK9 is not involved in the degradation of LDL receptors and BACE1 in the adult mouse brain von Liu, Mali, Wu, Guoxin, Baysarowich, Jennifer, Kavana, Michael, Addona, George H., Bierilo, Kathleen K., Mudgett, John S., Pavlovic, Guillaume, Sitlani, Ayesha, Renger, John J., Hubbard, Brian K., Fisher, Timothy S., Zerbinatti, Celina V.

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Discovery of heterocyclic replacements for the coumarin core of anti-tubercular FadD32 inhibitors von Fang, Chao, Lee, Katie K., Nietupski, Raymond, Bates, Robert H., Fernandez-Menendez, Raquel, Lopez-Roman, Eva Maria, Guijarro-Lopez, Laura, Yin, Yunxing, Peng, Zuozhong, Gomez, James E., Fisher, Stewart, Barros-Aguirre, David, Hubbard, Brian K., Serrano-Wu, Michael H., Hung, Deborah T.

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siRNA-induced liver ApoB knockdown lowers serum LDL-cholesterol in a mouse model with human-like serum lipids[S] von Tadin-Strapps, Marija, Peterson, Laurence B., Cumiskey, Anne-Marie, Rosa, Raymond L., Mendoza, Vivienne Halili, Castro-Perez, Jose, Puig, Oscar, Zhang, Liwen, Strapps, Walter R., Yendluri, Satyasri, Andrews, Lori, Pickering, Victoria, Rice, Julie, Luo, Lily, Chen, Zhu, Tep, Samnang, Ason, Brandon, Somers, Elizabeth Polizzi, Sachs, Alan B., Bartz, Steven R., Tian, Jenny, Chin, Jayne, Hubbard, Brian K., Wong, Kenny K., Mitnaul, Lyndon J.

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On-and Off-Target Pharmacology of Torcetrapib: Current Understanding and Implications for the Structure Activity Relationships (SAR), Discovery and Development of Cholesteryl Ester... von Johns, Douglas G., Duffy, Joseph, Fisher, Timothy, Hubbard, Brian K., Forrest, Michael J.

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A Methodology for Classifying Root Causes of Outbreaks of Legionnaires' Disease: Deficiencies in Environmental Control and Water Management von Clopper, Benjamin R, Kunz, Jasen M, Salandy, Simone W, Smith, Jessica C, Hubbard, Brian C, Sarisky, John P

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Localization of Fatty Acyl and Double Bond Positions in Phosphatidylcholines Using a Dual Stage CID Fragmentation Coupled with Ion Mobility Mass Spectrometry von Castro-Perez, Jose, Roddy, Thomas P., Nibbering, Nico M. M., Shah, Vinit, McLaren, David G., Previs, Stephen, Attygalle, Athula B., Herath, Kithsiri, Chen, Zhu, Wang, Sheng-Ping, Mitnaul, Lyndon, Hubbard, Brian K., Vreeken, Rob J., Johns, Douglas G., Hankemeier, Thomas

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What Actions Are Health Departments Taking to Improve Safe Drinking Water Programs? von Lamers, Vanessa, Hubbard, Brian C

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A rapid method for cross-species quantitation of apolipoproteins A1, B48 and B100 in plasma by ultra-performance liquid chromatography/tandem mass spectrometry von Lassman, Michael E., McLaughlin, Theresa M., Somers, Elizabeth P., Stefanni, Alice C., Chen, Zhu, Murphy, Beth Ann, Bierilo, Kathleen K., Flattery, Amy M., Wong, Kenneth K., Castro-Perez, Jose M., Hubbard, Brian K., Roddy, Thomas P.

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