Oxidative Stress and Cell Senescence Combine to Cause Maximal Renal Tubular Epithelial Cell Dysfunction and Loss in an in vitro Model of Kidney Disease von Small, David M., Bennett, Nigel C., Roy, Sandrine, Gabrielli, Brian G., Johnson, David W., Gobe, Glenda C.

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High-content imaging of neutral lipid droplets with 1,6-diphenylhexatriene von Ranall, Max V, Gabrielli, Brian G, Gonda, Thomas J

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RNA Interference against Human Papillomavirus Oncogenes in Cervical Cancer Cells Results in Increased Sensitivity to Cisplatin von Putral, Lisa N, Bywater, Megan J, Gu, Wenyi, Saunders, Nicholas A, Gabrielli, Brian G, Leggatt, Graham R, McMillan, Nigel A J

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Adaptation and validation of DNA synthesis detection by fluorescent dye derivatization for high-throughput screening von Ranall, Max V, Gabrielli, Brian G, Gonda, Thomas J

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Cdk1/Erk2- and Plk1-Dependent Phosphorylation of a Centrosome Protein, Cep55, Is Required for Its Recruitment to Midbody and Cytokinesis von Fabbro, Megan, Zhou, Bin-Bing, Takahashi, Mikiko, Sarcevic, Boris, Lal, Preeti, Graham, Mark E., Gabrielli, Brian G., Robinson, Phillip J., Nigg, Erich A., Ono, Yoshitaka, Khanna, Kum Kum

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Mechanism of action of the third generation benzopyrans and evaluation of their broad anti-cancer activity in vitro and in vivo von Stevenson, Alexander J., Ager, Eleanor I., Proctor, Martina A., Škalamera, Dubravka, Heaton, Andrew, Brown, David, Gabrielli, Brian G.

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Mechanism of Mitosis-specific Activation of MEK1 von Harding, Angus, Giles, Nichole, Burgess, Andrew, Hancock, John F., Gabrielli, Brian G.

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Abstract 3586: Overexpression of Emi1 causes chromosomal instability and cancer von Vaidyanathan, Srividya, Cato, Kathleen, Pavey, Sandra, Haass, Nikolas K., Gabrielli, Brian G., Duijf, Pascal HG

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Histone deacetylase inhibitors trigger a G2 checkpoint in normal cells that is defective in tumor cells von Qiu, L, Burgess, A, Fairlie, D P, Leonard, H, Parsons, P G, Gabrielli, B G

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Centrosomal and Cytoplasmic Cdc2/Cyclin B1 Activation Precedes Nuclear Mitotic Events von De Souza, Colin P.C., Ellem, Kay A.O., Gabrielli, Brian G.

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Requirement for Cdk2 in Cytostatic Factor-Mediated Metaphase II Arrest von Gabrielli, Brian G., Roy, Linda M., Maller, James L.

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CDKN2A/p16 is inactivated in most melanoma cell lines von CASTELLANO, M, POLLOCK, P. M, WALTERS, M. K, SPARROW, L. E, DOWN, L. M, GABRIELLI, B. G, PARSONS, P. G, HAYWARD, N. K

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Histone Hyperacetylation Induced by Histone Deacetylase Inhibitors Is Not Sufficient to Cause Growth Inhibition in Human Dermal Fibroblasts von Brinkmann, Hannah, Dahler, Alison L., Popa, Claudia, Serewko, Magdalena M., Parsons, Peter G., Gabrielli, Brian G., Burgess, Andrew J., Saunders, Nicholas A.

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Cytoplasmic accumulation of cdc25B phosphatase in mitosis triggers centrosomal microtubule nucleation in HeLa cells von Gabrielli, B G, De Souza, C P, Tonks, I D, Clark, J M, Hayward, N K, Ellem, K A

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Abstract 1443: CHKing melanoma: CHK1 inhibitor +low dose hydroxyurea triggers immunogenic cell death and immunostimulatory cytokine expression to drive an anti-tumor immune respons... von Gabrielli, Brian G., Proctor, Martina, Cruz, Jazmina Gonzalez, Zeng, Bijun, Dolcetti, Riccardo, Keane, Colm, Haass, Nikolas, Wells, James

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Abstract 1236: Subclinical doses and choice of replication stress inducer in combination with CHK1 inhibitors for optimal tumor control and immune responses in vitro and in vivo von Oo, Zay Yar, Proctor, Martina, Stevenson, Alex, Nazareth, Deborah, Larsen, Jill, Haass, Nikolas, Gabrielli, Brian G.

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Hyperphosphorylation of the N-terminal Domain of Cdc25 Regulates Activity toward Cyclin B1/Cdc2 But Not Cyclin A/Cdk2 von Gabrielli, Brian G., Clark, Joanne M., McCormack, Andrew K., Ellem, Kay A.O.

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Functional reassessment of P16 variants using a transfection‐based assay von Walker, Graeme J., Gabrielli, Brian G., Castellano, Marina, Hayward, Nicholas K.

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A Cyclin D-Cdk4 Activity Required for G2 Phase Cell Cycle Progression Is Inhibited in Ultraviolet Radiation-induced G2 Phase Delay von Gabrielli, Brian G., Sarcevic, Boris, Sinnamon, Joanne, Walker, Graeme, Castellano, Marina, Wang, Xue-Qing, Ellem, Kay A.O.

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Abstract A069: Increasing replication stress by reducing nucleoside levels sensitizes melanomas and non-small cell lung cancers to CHK1 inhibitor in vitro and in vivo von Oo, Zay Yar, Proctor, Martina, Stevenson, Alexander, Larsen, Jill, Gabrielli, Brian G.

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