The microglial P2Y6 receptor mediates neuronal loss and memory deficits in neurodegeneration von Puigdellívol, Mar, Milde, Stefan, Vilalta, Anna, Cockram, Tom O.J., Allendorf, David H., Lee, Jeffrey Y., Dundee, Jacob M., Pampuščenko, Katryna, Borutaite, Vilmante, Nuthall, Hugh N., Brelstaff, Jack H., Spillantini, Maria Grazia, Brown, Guy C.

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Microglia become hypofunctional and release metalloproteases and tau seeds when phagocytosing live neurons with P301S tau aggregates von Brelstaff, Jack H, Mason, Matthew, Katsinelos, Taxiarchis, McEwan, William A, Ghetti, Bernardino, Tolkovsky, Aviva M, Spillantini, Maria Grazia

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The delayed kinetics of Myddosome formation explains why amyloid-beta aggregates trigger Toll-like receptor 4 less efficiently than lipopolysaccharide von Li, Bing, Suresh, Prasanna, Brelstaff, Jack, Kedia, Shekhar, Bryant, Clare E, Klenerman, David

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Characterization of full-length p53 aggregates and their kinetics of formation von Julian, Linda, Sang, Jason C., Wu, Yunzhao, Meisl, Georg, Brelstaff, Jack H., Miller, Alyssa, Cheetham, Matthew R., Vendruscolo, Michele, Knowles, Tuomas P.J., Ruggeri, Francesco Simone, Bryant, Clare, Ros, Susana, Brindle, Kevin M., Klenerman, David

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ASC specks as a single-molecule fluid biomarker of inflammation in neurodegenerative diseases von Lobanova, Evgeniia, Zhang, Yu P., Emin, Derya, Brelstaff, Jack, Kahanawita, Lakmini, Malpetti, Maura, Quaegebeur, Annelies, Triantafilou, Kathy, Triantafilou, Martha, Zetterberg, Henrik, Rowe, James B., Williams-Gray, Caroline H., Bryant, Clare Elizabeth, Klenerman, David

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A comparative clinical, pathological, biochemical and genetic study of fused in sarcoma proteinopathies von Lashley, Tammaryn, Rohrer, Jonathan D., Bandopadhyay, Rina, Fry, Charles, Ahmed, Zeshan, Isaacs, Adrian M., Brelstaff, Jack H., Borroni, Barbara, Warren, Jason D., Troakes, Claire, King, Andrew, Al-Saraj, Safa, Newcombe, Jia, Quinn, Niall, Ostergaard, Karen, Schrøder, Henrik Daa, Bojsen-Møller, Marie, Braendgaard, Hans, Fox, Nick C., Rossor, Martin N., Lees, Andrew J., Holton, Janice L., Revesz, Tamas

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PHOSPHATIDYLSERINE EXPOSURE ON CULTURED DORSAL ROOT GANGLIA NEURONS FROM P301S TAU MICE SUGGEST PHAGOPTOSIS AS AN EXTRINSIC ROUTE OF CELL DEATH IN TAUOPATHY von Brelstaff, Jack H, Tolkovsky, Aviva, Spillantini, Maria Grazia

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The fluorescent pentameric oligothiophene pFTAA identifies filamentous tau in live neurons cultured from adult P301S tau mice von Brelstaff, Jack, Ossola, Bernardino, Neher, Jonas J, Klingstedt, Therése, Nilsson, K Peter R, Goedert, Michel, Spillantini, Maria Grazia, Tolkovsky, Aviva M

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pFTAA： a high affinity oligothiophene probe that detects filamentous tau in vivo and in cultured neurons von Brelstaff, Jack, Spillantini, Maria Grazia, Tolkovsky, Aviva M

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Living Neurons with Tau Filaments Aberrantly Expose Phosphatidylserine and Are Phagocytosed by Microglia von Brelstaff, Jack, Tolkovsky, Aviva M., Ghetti, Bernardino, Goedert, Michel, Spillantini, Maria Grazia

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The delayed kinetics of Myddosome formation explains why amyloid-beta aggregates trigger Toll-like receptor 4 less efficiently than lipopolysaccharide von Li, Bing, Suresh, Prasanna, Brelstaff, Jack, Kedia, Shekhar, Bryant, Clare E, Klenerman, David

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Sensory Neurons from Tau Transgenic Mice and Their Utility in Drug Screening von Tolkovsky, Aviva M., Brelstaff, Jack

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The presence of heterogeneous nuclear ribonucleoproteins in frontotemporal lobar degeneration with FUS positive inclusions von Gami-Patel, Priya, Bandopadhyay, Rina, Brelstaff, Jack, Revesz, Tamas, Lashley, Tammaryn

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Axonal neuregulin 1 is a rate limiting but not essential factor for nerve remyelination von FRICKER, Florence R, ANTUNES-MARTINS, Ana, ORENGO, Christine, GARRATT, Alistair N, BIRCHMEIER, Carmen, BENNETT, David L. H, GALINO, Jorge, PARAMSOTHY, Remi, LA RUSSA, Federica, PERKINS, James, GOLDBERG, Rebecca, BRELSTAFF, Jack, NING ZHU, MCMAHON, Stephen B

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P1‐160: Phosphatidylserine Exposure on Cultured Dorsal Root Ganglia Neurons From P301S TAU Mice Suggest Phagoptosis as an Extrinsic Route of Cell Death in Tauopathy von Brelstaff, Jack H., Tolkovsky, Aviva, Spillantini, Maria Grazia

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NEURONS WITH TAU AGGREGATES EXPOSE PHOSPHATIDYLSERINE AND ARE PHAGOCYTOSED LIVE BY MICROGLIA von Brelstaff, Jack H., Tolkovsky, Aviva, Ghetti, Bernardino Francesco, Goedert, Michel, Spillantini, Maria Grazia

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P4‐257: NEURONS WITH TAU AGGREGATES EXPOSE PHOSPHATIDYLSERINE AND ARE PHAGOCYTOSED LIVE BY MICROGLIA von Brelstaff, Jack H., Tolkovsky, Aviva, Ghetti, Bernardino Francesco, Goedert, Michel, Spillantini, Maria Grazia

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Transportin1: a marker of FTLD-FUS von Brelstaff, Jack, Lashley, Tammaryn, Holton, Janice L., Lees, Andrew J., Rossor, Martin N., Bandopadhyay, Rina, Revesz, Tamas

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The microglial P2Y 6 receptor mediates neuronal loss and memory deficits in neurodegeneration von Puigdellívol, Mar, Milde, Stefan, Vilalta, Anna, Cockram, Tom O J, Allendorf, David H, Lee, Jeffrey Y, Dundee, Jacob M, Pampuščenko, Katryna, Borutaite, Vilmante, Nuthall, Hugh N, Brelstaff, Jack H, Spillantini, Maria Grazia, Brown, Guy C

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The delayed kinetics of Myddosome formation explains why amyloid-beta aggregates trigger Toll-like receptor 4 less efficiently than lipopolysaccharide von Li, Bing, Suresh, Prasanna, Brelstaff, Jack, Kedia, Shekhar, Bryant, Clare E, Klenerman, David

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