GDF-15 Neutralization Alleviates Platinum-Based Chemotherapy-Induced Emesis, Anorexia, and Weight Loss in Mice and Nonhuman Primates von Breen, Danna M., Kim, Hanna, Bennett, Donald, Calle, Roberto A., Collins, Susie, Esquejo, Ryan M., He, Tao, Joaquim, Stephanie, Joyce, Alison, Lambert, Matthew, Lin, Laura, Pettersen, Betty, Qiao, Shuxi, Rossulek, Michelle, Weber, Gregory, Wu, Zhidan, Zhang, Bei B., Birnbaum, Morris J.

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Stimulation of muscle cell glucose uptake by resveratrol through sirtuins and AMPK von Breen, Danna M., Sanli, Toran, Giacca, Adria, Tsiani, Evangelia

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Resveratrol activates duodenal Sirt1 to reverse insulin resistance in rats through a neuronal network von Côté, Clémence D, Rasmussen, Brittany A, Duca, Frank A, Zadeh-Tahmasebi, Melika, Baur, Joseph A, Daljeet, Mira, Breen, Danna M, Filippi, Beatrice M, Lam, Tony K T

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Activation of the hypothalamic–pituitary–adrenal axis by exogenous and endogenous GDF15 von Cimino, Irene, Kim, Hanna, Tung, Y. C. Loraine, Pedersen, Kent, Rimmington, Debra, Tadross, John A., Kohnke, Sara N., Neves-Costa, Ana, Barros, André, Joaquim, Stephanie, Bennett, Don, Melvin, Audrey, Lockhart, Samuel M., Rostron, Anthony J., Scott, Jonathan, Liu, Hui, Burling, Keith, Barker, Peter, Clatworthy, Menna R., Lee, E-Chiang, Simpson, A. John, Yeo, Giles S. H., Moita, Luís F., Bence, Kendra K., Jørgensen, Sebastian Beck, Coll, Anthony P., Breen, Danna M., O’Rahilly, Stephen

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Phase 2 study of the efficacy and safety of ponsegromab in patients with cancer cachexia: PROACC‐1 study design von Groarke, John D., Crawford, Jeffrey, Collins, Susie M., Lubaczewski, Shannon L., Breen, Danna M., Harrington, Magdalena A., Jacobs, Ira, Qiu, Ruolun, Revkin, James, Rossulek, Michelle I., Saxena, Aditi R.

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Nutrient-Sensing Mechanisms in the Gut as Therapeutic Targets for Diabetes von BREEN, Danna M, RASMUSSEN, Brittany A, COTE, Clémence D, MARGARET JACKSON, V, LAM, Tony K. T

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Resveratrol Inhibits Neointimal Growth after Arterial Injury in High-Fat-Fed Rodents: The Roles of SIRT1 and AMPK von Guo, June, Pereira, Troy J., Mori, Yusaku, Gonzalez Medina, Marel, Breen, Danna M., Dalvi, Prasad S., Zhang, Hangjun, McCole, Declan F., McBurney, Michael W., Heximer, Scott P., Tsiani, Evangelia L., Dolinsky, Vernon W., Giacca, Adria

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Pharmacological inhibition of IRAK4 kinase activity does not prevent cachexia in mice with pancreatic cancer von Qiao, Shuxi, LaViolette, Brianna, Paulhus, Brianna LaCarubba, Li, Xiangping, Litchfield, John, Li, Zhenhong, Stansfield, John C., Gieseck, Richard L., Zhang, Bei B., Breen, Danna M.

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Jejunal Leptin-PI3K Signaling Lowers Glucose Production von Rasmussen, Brittany A., Breen, Danna M., Duca, Frank A., Côté, Clémence D., Zadeh-Tahmasebi, Melika, Filippi, Beatrice M., Lam, Tony K.T.

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In vivo effects of polyunsaturated, monounsaturated, and saturated fatty acids on hepatic and peripheral insulin sensitivity von Pereira, Sandra, Breen, Danna M, Naassan, Anthony E, Wang, Penny Y.T, Uchino, Hiroshi, Fantus, I. George, Carpentier, André C, Gutierrez-Juarez, Roger, Brindley, David N, Lam, Tony K.T, Giacca, Adria

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Growth differentiation factor 15 neutralization does not impact anorexia or survival in lipopolysaccharide-induced inflammation von Breen, Danna M., Jagarlapudi, Srinath, Patel, Anita, Zou, Chang, Joaquim, Stephanie, Li, Xiangping, Kang, Liya, Pang, Jincheng, Hales, Katherine, Ziso-Qejvanaj, Enida, Vera, Nicholas B., Bennett, Donald, He, Tao, Lambert, Matthew, Kelleher, Kerry, Wu, Zhidan, Zhang, Bei B., Lin, Laura, Seeley, Randy J., Bezy, Olivier

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Insulin Increases Reendothelialization and Inhibits Cell Migration and Neointimal Growth After Arterial Injury von BREEN, Danna M, CHAN, Kalam K, BENDECK, Michelle P, GIACCA, Adria, DHALIWALL, Jiwanjeet K, WARD, Michael R, AL KOUDSI, Nael, LAM, Loretta, DE SOUZA, Melissa, GHANIM, Husam, DANDONA, Paresh, STEWART, Duncan J

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Jejunal nutrient sensing is required for duodenal-jejunal bypass surgery to rapidly lower glucose concentrations in uncontrolled diabetes von Breen, Danna M, Rasmussen, Brittany A, Kokorovic, Andrea, Wang, Rennian, Cheung, Grace W C, Lam, Tony K T

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Frequency of weight and body composition increases in advanced non-small cell lung cancer patients during first line therapy von Bonomi, Philip, Moudgalya, Hita, Gomez, Sandra L, Shah, Palmi, Basu, Sanjib, Batus, Marta, Martinka, Levi B, Abdelkader, Ahmed, Tzameli, Iphigenia, Cobain, Sonia, Collins, Susie, Keliher, Edmund J, Breen, Danna M, Calle, Roberto A, Fidler, Mary Jo, Borgia, Jeffrey A

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Characterization of cachexia in the human fibrosarcoma HT‐1080 mouse tumour model von Bernardo, Barbara, Joaquim, Stephanie, Garren, Jeonifer, Boucher, Magalie, Houle, Christopher, LaCarubba, Brianna, Qiao, Shuxi, Wu, Zhidan, Esquejo, Ryan M., Peloquin, Matthew, Kim, Hanna, Breen, Danna M.

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High-dose metformin (420 mg/kg daily p.o.) increases insulin sensitivity but does not affect neointimal thickness in the rat carotid balloon injury model of restenosis von Guo, June, Pereira, Troy J, Dalvi, Prasad, Yeung, Lucy Shu Nga, Swain, Nathan, Breen, Danna M, Lam, Loretta, Dolinsky, Vernon W, Giacca, Adria

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The effect of insulin to decrease neointimal growth after arterial injury is endothelial nitric oxide synthase-dependent von Guo, June, Breen, Danna M, Pereira, Troy J, Dalvi, Prasad S, Zhang, Hangjun, Mori, Yusaku, Ghanim, Husam, Tumiati, Laura, Fantus, I. George, Bendeck, Michelle P, Dandona, Paresh, Rao, Vivek, Dolinsky, Vernon W, Heximer, Scott P, Giacca, Adria

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Lipid sensing in the gut, brain and liver von Rasmussen, Brittany A, Breen, Danna M, Lam, Tony K.T

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Resveratrol inhibits neointimal formation after arterial injury through an endothelial nitric oxide synthase-dependent mechanism von Breen, Danna M, Dolinsky, Vernon W, Zhang, Hangjun, Ghanim, Husam, Guo, June, Mroziewicz, Margaret, Tsiani, Evangelia L, Bendeck, Michelle P, Dandona, Paresh, Dyck, Jason R.B, Heximer, Scott P, Giacca, Adria

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Duodenal Activation of cAMP-Dependent Protein Kinase Induces Vagal Afferent Firing and Lowers Glucose Production in Rats von Rasmussen, Brittany A, Breen, Danna M, Luo, Ping, Cheung, Grace W.C, Yang, Clair S, Sun, Biying, Kokorovic, Andrea, Rong, Weifang, Lam, Tony K.T

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