Effect of the Phosphodiesterase 4 Inhibitor Roflumilast on Glucose Metabolism in Patients with Treatment-Naive, Newly Diagnosed Type 2 Diabetes Mellitus von Wouters, E. F. M, Bredenbröker, D, Teichmann, P, Brose, M, Rabe, K. F, Fabbri, L. M, Göke, B

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Roflumilast for asthma: Efficacy findings in mechanism of action studies von Bardin, P, Kanniess, F, Gauvreau, G, Bredenbröker, D, Rabe, K.F

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Roflumilast for asthma: Efficacy findings in placebo-controlled studies von Meltzer, E.O, Chervinsky, P, Busse, W, Ohta, K, Bardin, P, Bredenbröker, D, Bateman, E.D

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Roflumilast for asthma: Efficacy findings in non-placebo-controlled comparator and dosing studies von Bateman, E.D, Bousquet, J, Aubier, M, Bredenbröker, D, O'Byrne, P.M

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Roflumilast for asthma: Safety findings from a pooled analysis of ten clinical studies von Chervinsky, P, Meltzer, E.O, Busse, W, Ohta, K, Bardin, P, Bredenbröker, D, Bateman, E.D

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Roflumilast and dyspnea in patients with moderate to very severe chronic obstructive pulmonary disease: a pooled analysis of four clinical trials von Rennard, Stephen I, Sun, Shawn X, Tourkodimitris, Stavros, Rowe, Paul, Goehring, Udo M, Bredenbröker, Dirk, Calverley, Peter M A

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Comparison of roflumilast, an oral anti‐inflammatory, with beclomethasone dipropionate in the treatment of persistent asthma von Bousquet, J., Aubier, M., Sastre, J., Izquierdo, J. L., Adler, L. M., Hofbauer, P., Rost, K.‐D., Harnest, U., Kroemer, B., Albrecht, A., Bredenbröker, D.

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Roflumilast with long-acting β 2 -agonists for COPD: influence of exacerbation history von Bateman, E.D., Rabe, K.F., Calverley, P.M.A., Goehring, U.M., Brose, M., Bredenbröker, D., Fabbri, L.M.

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Roflumilast, a Phosphodiesterase 4 Inhibitor, Reduces Airway Hyperresponsiveness after Allergen Challenge von Louw, C., Williams, Z., Venter, L., Leichtl, S., Schmid-Wirlitsch, C., Bredenbröker, D., Bardin, P.G.

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Effects of the nitric oxide/cGMP system compared with the cAMP system on airway mucus secretion in the rat von Bredenbröker, Dirk, Dyarmand, Darius, Meingast, Uta, Fehmann, Hans-Christoph, Staats, Petra, Von Wichert, Peter, Wagner, Ulrich

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Roflumilast—an oral anti-inflammatory treatment for chronic obstructive pulmonary disease: a randomised controlled trial von Rabe, Klaus F, Bateman, Eric D, O'Donnell, Denis, Witte, Stephan, Bredenbröker, Dirk, Bethke, Thomas D

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Reduction in sputum neutrophil and eosinophil numbers by the PDE4 inhibitor roflumilast in patients with COPD von Grootendorst, Diana C, Gauw, Stefanie A, Verhoosel, Renate M, Sterk, Peter J, Hospers, Jeannette J, Bredenbröker, Dirk, Bethke, Thomas D, Hiemstra, Pieter S, Rabe, Klaus F

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Efficacy of Roflumilast in the COPD Frequent Exacerbator Phenotype von Wedzicha, Jadwiga A., MD, Rabe, Klaus F., MD, Martinez, Fernando J., MD, Bredenbröker, Dirk, MD, Brose, Manja, MS, Goehring, Udo-Michael, MD, Calverley, Peter M.A., MD

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Effects of VIP and Related Peptides on Airway Mucus Secretion from Isolated Rat Trachea von Wagner, Ulrich, Bredenbröker, Dirk, Storm, Burkhard, Tackenberg, Björn, Fehmann, Hans-Christoph, von Wichert, Peter

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Avoiding backward steps in COPD: looking again at roflumilast von Bateman, E.D., Rabe, K.F., Calverley, P.M.A., Goehring, U.M., Brose, M., Bredenbröker, D., Fabbri, L.

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Roflumilast with long-acting β2-agonists for COPD: influence of exacerbation history von BATEMAN, E. D, RABE, K. F, CALVERLEY, P. M. A, GOEHRING, U. M, BROSE, M, BREDENBRÖKER, D, FABBRI, L. M

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Cardiovascular Safety in Patients Receiving Roflumilast for the Treatment of COPD von White, William B., MD, Cooke, Glen E., MD, Kowey, Peter R., MD, Calverley, Peter M.A., MD, Bredenbröker, Dirk, MD, Goehring, Udo-Michael, MD, Zhu, Haiyuan, PhD, Lakkis, Hassan, PhD, Mosberg, Hans, MD, Rowe, Paul, MD, Rabe, Klaus F., MD, PhD

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Effects of selective tachykinin-receptor antagonists on tachykinin-induced airway mucus secretion in the rat von Wagner, U., Fehmann, H.-C., Bredenbröker, D., Klüber, D., Lange, A., Wichert, P.von

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Galanin and somatostatin inhibition of neurokinin A and B induced airway mucus secretion in the rat von Wagner, U, Fehmann, H.C, Bredenbröker, D, Yu, F, Barth, P.J, von Wichert, P

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Roflumilast, an oral, once-daily phosphodiesterase 4 inhibitor, attenuates allergen-induced asthmatic reactions von van Schalkwyk, Emmerentia, Strydom, K., Williams, Zelda, Venter, Louis, Leichtl, Stefan, Schmid-Wirlitsch, Christine, Bredenbröker, Dirk, Bardin, Philip G.

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