Inhibition of insulin-like growth factor-I receptor (IGF-IR) signaling and tumor cell growth by a fully human neutralizing anti–IGF-IR antibody von Wang, Yan, Hailey, Judith, Williams, Denise, Wang, Yaolin, Lipari, Philip, Malkowski, Michael, Wang, Xiaoying, Xie, Lei, Li, Guanghua, Saha, Deba, Ling, Wai Lam W, Cannon-Carlson, Susan, Greenberg, Robert, Ramos, Robert A, Shields, Robert, Presta, Leonard, Brams, Peter, Bishop, W Robert, Pachter, Jonathan A

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Genome-wide association analyses of risk tolerance and risky behaviors in over 1 million individuals identify hundreds of loci and shared genetic influences von Karlsson Linnér, Richard, Biroli, Pietro, Kong, Edward, Meddens, S. Fleur W., Wedow, Robbee, Fontana, Mark Alan, Lebreton, Maël, Tino, Stephen P., Abdellaoui, Abdel, Hammerschlag, Anke R., Nivard, Michel G., Okbay, Aysu, Rietveld, Cornelius A., Timshel, Pascal N., Trzaskowski, Maciej, Vlaming, Ronald de, Zünd, Christian L., Bao, Yanchun, Buzdugan, Laura, Caplin, Ann H., Chen, Chia-Yen, Eibich, Peter, Fontanillas, Pierre, Gonzalez, Juan R., Joshi, Peter K., Karhunen, Ville, Kleinman, Aaron, Levin, Remy Z., Lill, Christina M., Meddens, Gerardus A., Muntané, Gerard, Sanchez-Roige, Sandra, Rooij, Frank J. van, Taskesen, Erdogan, Wu, Yang, Zhang, Futao, Auton, Adam, Boardman, Jason D., Clark, David W., Conlin, Andrew, Dolan, Conor C., Fischbacher, Urs, Groenen, Patrick J. F., Harris, Kathleen Mullan, Hasler, Gregor, Hofman, Albert, Ikram, Mohammad A., Jain, Sonia, Karlsson, Robert, Kessler, Ronald C., Kooyman, Maarten, MacKillop, James, Männikkö, Minna, Morcillo-Suarez, Carlos, McQueen, Matthew B., Schmidt, Klaus M., Smart, Melissa C., Sutter, Matthias, Thurik, A. Roy, Uitterlinden, André G., White, Jon, Wit, Harriet de, Yang, Jian, Bertram, Lars, Boomsma, Dorret I., Esko, Tõnu, Fehr, Ernst, Hinds, David A., Johannesson, Magnus, Kumari, Meena, Laibson, David, Magnusson, Patrik K. E., Meyer, Michelle N., Navarro, Arcadi, Palmer, Abraham A., Pers, Tune H., Posthuma, Danielle, Schunk, Daniel, Stein, Murray B., Svento, Rauli, Tiemeier, Henning, Timmers, Paul R. H. J., Turley, Patrick, Ursano, Robert J., Wagner, Gert G., Wilson, James F., Gratten, Jacob, Lee, James J., Cesarini, David, Benjamin, Daniel J., Koellinger, Philipp D., Beauchamp, Jonathan P.

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Cardiovascular Risk Factors and MRI Markers of Cerebral Small Vessel Disease: A Mendelian Randomization Study von Taylor-Bateman, Victoria, Gill, Dipender, Georgakis, Marios K., Malik, Rainer, Munroe, Patricia, Traylor, Matthew

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Epigenome-wide Association Study of Attention-Deficit/Hyperactivity Disorder Symptoms in Adults von van Dongen, Jenny, Zilhão, Nuno R., Sugden, Karen, Heijmans, Bastiaan T., ’t Hoen, Peter A.C., van Meurs, Joyce, Isaacs, Aaron, Jansen, Rick, Franke, Lude, Boomsma, Dorret I., Pool, René, van Dongen, Jenny, Hottenga, Jouke J., van Greevenbroek, Marleen M.J., Stehouwer, Coen D.A., van der Kallen, Carla J.H., Schalkwijk, Casper G., Wijmenga, Cisca, Zhernakova, Sasha, Tigchelaar, Ettje F., Slagboom, P. Eline, Beekman, Marian, Deelen, Joris, van Heemst, Diana, Veldink, Jan H., van den Berg, Leonard H., van Duijn, Cornelia M., Hofman, Bert A., Uitterlinden, André G., van Meurs, Joyce, Jhamai, P. Mila, Verbiest, Michael, Suchiman, H. Eka D., Verkerk, Marijn, van der Breggen, Ruud, van Rooij, Jeroen, Lakenberg, Nico, Mei, Hailiang, van Iterson, Maarten, van Galen, Michiel, Bot, Jan, Zhernakova, Dasha V., Hof, Peter van ’t, Deelen, Patrick, Nooren, Irene, Heijmans, Bastiaan T., Moed, Matthijs, Franke, Lude, Vermaat, Martijn, Luijk, René, Bonder, Marc Jan, van Dijk, Freerk, Arindrarto, Wibowo, Kielbasa, Szymon M., Swertz, Morris A., van Zwet, Erik. W., Hoen, Peter-Bram ’t, Heijmans, Bastiaan T., Hannon, Eilis J., Mill, Jonathan, Caspi, Avshalom, Agnew-Blais, Jessica, Arseneault, Louise, Corcoran, David L., Moffitt, Terrie E., Poulton, Richie, Franke, Barbara, Boomsma, Dorret I.

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DNA methylation signatures of aggression and closely related constructs: A meta-analysis of epigenome-wide studies across the lifespan von van Dongen, Jenny, Hagenbeek, Fiona A., Suderman, Matthew, Roetman, Peter J., Sugden, Karen, Chiocchetti, Andreas G., Ismail, Khadeeja, Mulder, Rosa H., Hafferty, Jonathan D., Adams, Mark J., Walker, Rosie M., Morris, Stewart W., Lahti, Jari, Küpers, Leanne K., Escaramis, Georgia, Alemany, Silvia, Jan Bonder, Marc, Meijer, Mandy, Ip, Hill F., Jansen, Rick, Baselmans, Bart M. L., Parmar, Priyanka, Lowry, Estelle, Streit, Fabian, Sirignano, Lea, Send, Tabea S., Frank, Josef, Jylhävä, Juulia, Wang, Yunzhang, Mishra, Pashupati Prasad, Colins, Olivier F., Corcoran, David L., Poulton, Richie, Mill, Jonathan, Hannon, Eilis, Arseneault, Louise, Korhonen, Tellervo, Vuoksimaa, Eero, Felix, Janine F., Bakermans-Kranenburg, Marian J., Campbell, Archie, Czamara, Darina, Binder, Elisabeth, Corpeleijn, Eva, Gonzalez, Juan R., Grazuleviciene, Regina, Gutzkow, Kristine B., Evandt, Jorunn, Vafeiadi, Marina, Klein, Marieke, van der Meer, Dennis, Ligthart, Lannie, Kluft, Cornelis, Davies, Gareth E., Hakulinen, Christian, Keltikangas-Järvinen, Liisa, Franke, Barbara, Freitag, Christine M., Konrad, Kerstin, Hervas, Amaia, Fernández-Rivas, Aranzazu, Vetro, Agnes, Raitakari, Olli, Lehtimäki, Terho, Vermeiren, Robert, Strandberg, Timo, Räikkönen, Katri, Snieder, Harold, Witt, Stephanie H., Deuschle, Michael, Pedersen, Nancy L., Hägg, Sara, Sunyer, Jordi, Franke, Lude, Kaprio, Jaakko, Ollikainen, Miina, Moffitt, Terrie E., Tiemeier, Henning, van IJzendoorn, Marinus H., Relton, Caroline, Vrijheid, Martine, Sebert, Sylvain, Jarvelin, Marjo-Riitta, Caspi, Avshalom, Evans, Kathryn L., McIntosh, Andrew M., Bartels, Meike, Boomsma, Dorret I.

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A humanized anti-human CD154 monoclonal antibody blocks CD154–CD40 mediated human B cell activation von Brams, Peter, Black, Amelia, Padlan, Eduardo A, Hariharan, Kandasamy, Leonard, John, Chambers-Slater, Karen, Noelle, Randolph J, Newman, Roland

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Approval Voting von Brams, Steven, Fishburn, Peter C

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A natively paired antibody library yields drug leads with higher sensitivity and specificity than a randomly paired antibody library von Adler, Adam S, Bedinger, Daniel, Adams, Matthew S, Asensio, Michael A, Edgar, Robert C, Leong, Renee, Leong, Jackson, Mizrahi, Rena A, Spindler, Matthew J, Bandi, Srinivasa Rao, Huang, Haichun, Tawde, Pallavi, Brams, Peter, Johnson, David S

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Genome-wide identification of genes regulating DNA methylation using genetic anchors for causal inference von Hop, Paul J., Luijk, Rene, Daxinger, Lucia, van Iterson, Maarten, Dekkers, Koen F., Jansen, Rick, van Meurs, Joyce B. J., 't Hoen, Peter A. C., Ikram, M. Arfan, van Greevenbroek, Marleen M. J., Boomsma, Dorret, Slagboom, P. Eline, Veldink, Jan H., van Zwet, Erik W., Heijmans, Bastiaan T.

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DNA methylation in peripheral tissues and left-handedness von Odintsova, Veronika V., Suderman, Matthew, Hagenbeek, Fiona A., Caramaschi, Doretta, Hottenga, Jouke-Jan, Pool, René, Dolan, Conor V., Ligthart, Lannie, van Beijsterveldt, Catharina E. M., Willemsen, Gonneke, de Geus, Eco J. C., Beck, Jeffrey J., Ehli, Erik A., Cuellar-Partida, Gabriel, Evans, David M., Medland, Sarah E., Relton, Caroline L., Boomsma, Dorret I., van Dongen, Jenny

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The use or generation of biomedical data and existing medicines to discover and establish new treatments for patients with rare diseases - recommendations of the IRDiRC Data Mining... von Southall, Noel T, Natarajan, Madhusudan, Lau, Lilian Pek Lian, Jonker, Anneliene Hechtelt, Deprez, Benoît, Guilliams, Tim, Hunter, Lawrence, Rademaker, Carin Ma, Hivert, Virginie, Ardigò, Diego

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A characterization of cis- and trans-heritability of RNA-Seq-based gene expression von Ouwens, Klaasjan G., Jansen, Rick, Nivard, Michel G., van Dongen, Jenny, Frieser, Maia J., Hottenga, Jouke-Jan, Arindrarto, Wibowo, Claringbould, Annique, van Iterson, Maarten, Mei, Hailiang, Franke, Lude, Heijmans, Bastiaan T., 't Hoen, Peter A. C., van Meurs, Joyce, Brooks, Andrew, Penninx, Brenda W. J. H., Boomsma, Dorret, Isaacs, Aaron, Pool, Rene, Hottenga, Jouke J., van Greevenbroek, Marleen M. J., Stehouwer, Coen D. A., van der Kallen, Carla J. H., Schalkwijk, Casper G., Wijmenga, Cisca, Zhernakova, Sasha, Tigchelaar, Ettje F., Slagboom, P. Eline, Beekman, Marian, Deelen, Joris, van Heemst, Diana, Veldink, Jan H., van den Berg, Leonard H., van Duijn, Cornelia M., Hofman, Bert A., Uitterlinden, Andre G., Jhamai, P. Mila, Verbiest, Michael, Suchiman, H. Eka D., Verkerk, Marijn, van der Breggen, Ruud, van Rooij, Jeroen, Lakenberg, Nico, van Galen, Michiel, Bot, Jan, Zhernakova, Dasha, van't Hof, Peter, Deelen, Patrick, Nooren, Irene, Moed, Matthijs, Vermaat, Martijn, Luijk, Rene, Bonder, Marc Jan, van Dijk, Freerk, Kielbasa, Szymon M., Swertz, Morris A., van Zwet, Erik W., 't Hoen, Peter-Bram

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Abstract 3590: ZL-1218, a novel anti-CCR8 antibody, exerts potent antitumor effect by depleting intratumoral regulatory T cells von Zhang, Jing, Shi, Wenhua, Chen, Min, Dai, Xinchuan, Liu, Hongshui, Li, Shou, Wang, Lina, Sun, Bee-Chun, You, Monica, Morton, Vivian, Ye, Qiuping, Kang, Lishan, Wan, Bing, Brams, Peter, Bellovin, David I.

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Correction for both common and rare cell types in blood is important to identify genes that correlate with age von Pellegrino-Coppola, Damiano, Claringbould, Annique, Stutvoet, Maartje, Boomsma, Dorret I., Ikram, M. Arfan, Slagboom, P. Eline, Westra, Harm-Jan, Franke, Lude

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CHIMERIC TRANSGENIC IMMUNOGLOBULIN MICE WITH AN ALTERED HEAVY CHAIN LOCUS AND METHODS OF MAKING AND USING SAME von ROHRER, Daniel, BRAMS, Peter

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HUMAN IMMUNOGLOBULIN BINARY LIGHT CHAIN TRANSGENE CONSTRUCTS AND USES THEREOF von Rohrer, Daniel, Brams, Peter

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CHIMERIC TRANSGENIC IMMUNOGLOBULIN MICE WITH AN ALTERED HEAVY CHAIN LOCUS AND METHODS OF MAKING AND USING SAME von Rohrer, Daniel, Brams, Peter

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HUMAN IMMUNOGLOBULIN BINARY LIGHT CHAIN TRANSGENE CONSTRUCTS AND USES THEREOF von ROHRER, Daniel, BRAMS, Peter

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CHIMERIC TRANSGENIC IMMUNOGLOBULIN MICE WITH AN ALTERED HEAVY CHAIN LOCUS AND METHODS OF MAKING AND USING SAME von ROHRER, Daniel, BRAMS, Peter

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HUMAN IMMUNOGLOBULIN HEAVY CHAIN LONG CDR3 TRANSGENE CONSTRUCTS AND USES THEREOF von ROHRER, Daniel, BRAMS, Peter

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