Oncogene-induced senescence : Putting the brakes on tumor development von BRAIG, Melanie, SCHMITT, Clemens A

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BCL6-mediated repression of p53 is critical for leukemia stem cell survival in chronic myeloid leukemia von Hurtz, Christian, Hatzi, Katerina, Cerchietti, Leandro, Braig, Melanie, Park, Eugene, Kim, Yong-mi, Herzog, Sebastian, Ramezani-Rad, Parham, Jumaa, Hassan, Müller, Martin C, Hofmann, Wolf-Karsten, Hochhaus, Andreas, Ye, B Hilda, Agarwal, Anupriya, Druker, Brian J, Shah, Neil P, Melnick, Ari M, Müschen, Markus

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Current aspects in resistance against tyrosine kinase inhibitors in chronic myelogenous leukemia von Balabanov, Stefan, Braig, Melanie, Brümmendorf, Tim H.

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Expression of eukaryotic initiation factor 5A and hypusine forming enzymes in glioblastoma patient samples: implications for new targeted therapies von Preukschas, Michael, Hagel, Christian, Schulte, Alexander, Weber, Kristoffer, Lamszus, Katrin, Sievert, Henning, Pällmann, Nora, Bokemeyer, Carsten, Hauber, Joachim, Braig, Melanie, Balabanov, Stefan

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Ubiquitin carboxyl-terminal hydrolase 1 (UCHL1) is a potential tumour suppressor in prostate cancer and is frequently silenced by promoter methylation von Ummanni, Ramesh, Jost, Edgar, Braig, Melanie, Lohmann, Frithjof, Mundt, Frederike, Barett, Christine, Schlomm, Thorsten, Sauter, Guido, Senff, Tina, Bokemeyer, Carsten, Sültmann, Holger, Meyer-Schwesinger, Catherine, Brümmendorf, Tim H, Balabanov, Stefan

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The expression of podocyte-specific proteins in parietal epithelial cells is regulated by protein degradation von Guhr, Sebastian S.O., Sachs, Marlies, Wegner, Anne, Becker, Jan U., Meyer, Tobias N., Kietzmann, Leonie, Schlossarek, Saskia, Carrier, Lucie, Braig, Melanie, Jat, Parmjit S., Stahl, Rolf A.K., Meyer-Schwesinger, Catherine

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A novel mouse model for inhibition of DOHH-mediated hypusine modification reveals a crucial function in embryonic development, proliferation and oncogenic transformation von Sievert, Henning, Pällmann, Nora, Miller, Katharine K, Hermans-Borgmeyer, Irm, Venz, Simone, Sendoel, Ataman, Preukschas, Michael, Schweizer, Michaela, Boettcher, Steffen, Janiesch, P Christoph, Streichert, Thomas, Walther, Reinhard, Hengartner, Michael O, Manz, Markus G, Brümmendorf, Tim H, Bokemeyer, Carsten, Braig, Melanie, Hauber, Joachim, Duncan, Kent E, Balabanov, Stefan

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Aurora Kinase Inhibitor PHA-739358 Suppresses Growth of Hepatocellular Carcinoma In Vitro and in a Xenograft Mouse Model von Benten, Daniel, Keller, Gunhild, Quaas, Alexander, Schrader, Jorg, Gontarewicz, Artur, Balabanov, Stefan, Braig, Melanie, Wege, Henning, Moll, Jurgen, Lohse, Ansgar W., Brummendorf, Tim H.

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Abcg2 overexpression represents a novel mechanism for acquired resistance to the multi-kinase inhibitor Danusertib in BCR-ABL-positive cells in vitro von Balabanov, Stefan, Gontarewicz, Artur, Keller, Gunhild, Raddrizzani, Laura, Braig, Melanie, Bosotti, Roberta, Moll, Jürgen, Jost, Edgar, Barett, Christine, Rohe, Imke, Bokemeyer, Carsten, Holyoake, Tessa L, Brümmendorf, Tim H

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Combination of a proteomics approach and reengineering of meso scale network models for prediction of mode-of-action for tyrosine kinase inhibitors von Balabanov, Stefan, Wilhelm, Thomas, Venz, Simone, Keller, Gunhild, Scharf, Christian, Pospisil, Heike, Braig, Melanie, Barett, Christine, Bokemeyer, Carsten, Walther, Reinhard, Brümmendorf, Tim H, Schuppert, Andreas

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Oncogene-induced senescence as an initial barrier in lymphoma development von Schmitt, Clemens A, Braig, Melanie, Lee, Soyoung, Loddenkemper, Christoph, Rudolph, Cornelia, Peters, Antoine H.F.M, Schlegelberger, Brigitte, Stein, Harald, Dörken, Bernd, Jenuwein, Thomas

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Biological Relevance and Therapeutic Potential of the Hypusine Modification System von Pällmann, Nora, Braig, Melanie, Sievert, Henning, Preukschas, Michael, Hermans-Borgmeyer, Irm, Schweizer, Michaela, Nagel, Claus Henning, Neumann, Melanie, Wild, Peter, Haralambieva, Eugenia, Hagel, Christian, Bokemeyer, Carsten, Hauber, Joachim, Balabanov, Stefan

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BCL6 enables Ph+ acute lymphoblastic leukaemia cells to survive BCR–ABL1 kinase inhibition von Duy, Cihangir, Hurtz, Christian, Shojaee, Seyedmehdi, Cerchietti, Leandro, Geng, Huimin, Swaminathan, Srividya, Klemm, Lars, Kweon, Soo-mi, Nahar, Rahul, Braig, Melanie, Park, Eugene, Kim, Yong-mi, Hofmann, Wolf-Karsten, Herzog, Sebastian, Jumaa, Hassan, Koeffler, H. Phillip, Yu, J. Jessica, Heisterkamp, Nora, Graeber, Thomas G., Wu, Hong, Ye, B. Hilda, Melnick, Ari, Müschen, Markus

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Ets2 and protein kinase Cepsilon are important regulators of parathyroid hormone-related protein expression in MCF-7 breast cancer cells von LINDEMANN, Ralph K., BRAIG, Melanie, HAUSER, Craig A., NORDHEIM, Alfred, DITTMER, Jürgen

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Biological relevance and therapeutic potential of the hypusine modification system von Pallmann, Nora, Braig, Melanie, Sievert, Henning, Preukschas, Michael, Hermans-Borgmeyer, Irm, Schweizer, Michaela, Nagel, Claus Henning, Neumann, Melanie, Wild, Peter, Haralambieva, Eugenia, Hagel, Christian, Bokemeyer, Carsten, Hauber, Joachim, Balabanov, Stefan

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Molecular characterization of chromosomal band 5p15.33: A recurrent breakpoint region in mantle cell lymphoma involving the TERT–CLPTM1L locus von Schilling, Georgia, Penas, Eva Maria Murga, Janjetovic, Snjezana, Oliveira-Ferrer, Leticia, Braig, Melanie, Behrmann, Petra, Bokemeyer, Carsten, Dierlamm, Judith

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The metabolite 3-hydroxiglutaric acid effectively reduces glioblastoma growth in vivo by affecting the structural integrity of tumor vasculature von Oliveira-Ferrer, Leticia, Wellbrock, Jasmin, Braig, Melanie, Klokow, Marianne, Hauschild, Jessica, Bokemeyer, Carsten, Fiedler, Walter, Ergun, Suleyman, Schuch, Gunter

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BCR-ABL Cooperates With a “Telomere-Associated Secretory Phenotype” (TASP) To Facilitate Malignant Proliferation Of Hematopoietic Stem Cells von Brümmendorf, Tim H., Pällmann, Nora, Preukschas, Michael, Steinemann, Doris, Hofmann, Winfried, Gompf, Anne, Rudolph, Karl L., Bokemeyer, Carsten, Koschmieder, Steffen, Schuppert, Andreas, Balabanov, Stefan, Braig, Melanie

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Functional p53 is required for effective execution of telomerase inhibition in BCR-ABL–positive CML cells von Brassat, Ute, Balabanov, Stefan, Bali, Daniel, Dierlamm, Judith, Braig, Melanie, Hartmann, Ulrike, Sirma, Hüseyin, Günes, Cagatay, Wege, Henning, Fehse, Boris, Gontarewicz, Artur, Dikomey, Ekkehard, Borgmann, Kerstin, Brümmendorf, Tim H

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Protein-protein-interaction Network Organization of the Hypusine Modification System von Sievert, Henning, Venz, Simone, Platas-Barradas, Oscar, Dhople, Vishnu M., Schaletzky, Martin, Nagel, Claus-Henning, Braig, Melanie, Preukschas, Michael, Pällmann, Nora, Bokemeyer, Carsten, Brümmendorf, Tim H., Pörtner, Ralf, Walther, Reinhard, Duncan, Kent E., Hauber, Joachim, Balabanov, Stefan

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