Reprogramming Tumor-Associated Macrophages by Antibody Targeting Inhibits Cancer Progression and Metastasis von Georgoudaki, Anna-Maria, Prokopec, Kajsa E., Boura, Vanessa F., Hellqvist, Eva, Sohn, Silke, Östling, Jeanette, Dahan, Rony, Harris, Robert A., Rantalainen, Mattias, Klevebring, Daniel, Sund, Malin, Brage, Suzanne Egyhazi, Fuxe, Jonas, Rolny, Charlotte, Li, Fubin, Ravetch, Jeffrey V., Karlsson, Mikael C.I.

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Melanoma-Educated CD14+ Cells Acquire a Myeloid-Derived Suppressor Cell Phenotype through COX-2-Dependent Mechanisms von MAO, Yumeng, POSCHKE, Isabel, WENNERBERG, Erik, DE COANA, Yago Pico, BRAGE, Suzanne Egyhazi, SCHULTZ, Inkeri, HANSSON, Johan, MASUCCI, Giuseppe, LUNDQVIST, Andreas, KIESSLING, Rolf

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Targeting CDK2 overcomes melanoma resistance against BRAF and Hsp90 inhibitors von Azimi, Alireza, Caramuta, Stefano, Seashore‐Ludlow, Brinton, Boström, Johan, Robinson, Jonathan L, Edfors, Fredrik, Tuominen, Rainer, Kemper, Kristel, Krijgsman, Oscar, Peeper, Daniel S, Nielsen, Jens, Hansson, Johan, Egyhazi Brage, Suzanne, Altun, Mikael, Uhlen, Mathias, Maddalo, Gianluca

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AXL and CAV-1 play a role for MTH1 inhibitor TH1579 sensitivity in cutaneous malignant melanoma von Das, Ishani, Gad, Helge, Bräutigam, Lars, Pudelko, Linda, Tuominen, Rainer, Höiom, Veronica, Almlöf, Ingrid, Rajagopal, Varshni, Hansson, Johan, Helleday, Thomas, Egyházi Brage, Suzanne, Warpman Berglund, Ulrika

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Laminins 411 and 421 differentially promote tumor cell migration via α6β1 integrin and MCAM (CD146) von Ishikawa, Taichi, Wondimu, Zenebech, Oikawa, Yuko, Gentilcore, Giusy, Kiessling, Rolf, Egyhazi Brage, Suzanne, Hansson, Johan, Patarroyo, Manuel

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PTENP1-AS contributes to BRAF inhibitor resistance and is associated with adverse clinical outcome in stage III melanoma von Vidarsdottir, Linda, Azimi, Alireza, Das, Ishani, Sigvaldadottir, Ingibjorg, Suryo Rahmanto, Aldwin, Petri, Andreas, Kauppinen, Sakari, Ingvar, Christian, Jönsson, Göran, Olsson, Håkan, Frostvik Stolt, Marianne, Tuominen, Rainer, Sangfelt, Olle, Pokrovskaja Tamm, Katja, Hansson, Johan, Grandér, Dan, Egyházi Brage, Suzanne, Johnsson, Per

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MGMT promoter methylation is associated with temozolomide response and prolonged progression‐free survival in disseminated cutaneous melanoma von Tuominen, Rainer, Jewell, Rosalyn, van den Oord, Joost J., Wolter, Pascal, Stierner, Ulrika, Lindholm, Christer, Hertzman Johansson, Carolina, Lindén, Diana, Johansson, Hemming, Frostvik Stolt, Marianne, Walker, Christy, Snowden, Helen, Newton‐Bishop, Julia, Hansson, Johan, Egyházi Brage, Suzanne

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Combining ERBB family and MET inhibitors is an effective therapeutic strategy in cutaneous malignant melanoma independent of BRAF/NRAS mutation status von Das, Ishani, Wilhelm, Margareta, Höiom, Veronica, Franco Marquez, Rodolfo, Costa Svedman, Fernanda, Hansson, Johan, Tuominen, Rainer, Egyhàzi Brage, Suzanne

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Inhibiting insulin and mTOR signaling by afatinib and crizotinib combination fosters broad cytotoxic effects in cutaneous malignant melanoma von Das, Ishani, Chen, Huiqin, Maddalo, Gianluca, Tuominen, Rainer, Rebecca, Vito W., Herlyn, Meenhard, Hansson, Johan, Davies, Michael A., Egyházi Brage, Suzanne

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Silencing FLI or targeting CD13/ANPEP lead to dephosphorylation of EPHA2, a mediator of BRAF inhibitor resistance, and induce growth arrest or apoptosis in melanoma cells von Azimi, Alireza, Tuominen, Rainer, Costa Svedman, Fernanda, Caramuta, Stefano, Pernemalm, Maria, Frostvik Stolt, Marianne, Kanter, Lena, Kharaziha, Pedram, Lehtiö, Janne, Hertzman Johansson, Carolina, Höiom, Veronica, Hansson, Johan, Egyhazi Brage, Suzanne

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Presence of immune cells, low tumor proliferation and wild type BRAF mutation status is associated with a favourable clinical outcome in stage III cutaneous melanoma von Falkenius, Johan, Johansson, Hemming, Tuominen, Rainer, Frostvik Stolt, Marianne, Hansson, Johan, Egyhazi Brage, Suzanne

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BRAF inhibitors in cancer therapy von JOHANSSON, Carolina Hertzman, BRAGE, Suzanne Egyhazi

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Inflammation and Apolipoproteins Are Potential Biomarkers for Stratification of Cutaneous Melanoma Patients for Immunotherapy and Targeted Therapy von Karlsson, Max J., Svedman, Fernanda Costa, Tebani, Abdellah, Kotol, David, Hoiom, Veronica, Fagerberg, Linn, Edfors, Fredrik, Uhlen, Mathias, Brage, Suzanne Egyhazi, Maddalo, Gianluca

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Extracellular microvesicle microRNAs as predictive biomarkers for targeted therapy in metastastic cutaneous malignant melanoma von Svedman, Fernanda Costa, Lohcharoenkal, Warangkana, Bottai, Matteo, Brage, Suzanne Egyhazi, Sonkoly, Enikö, Hansson, Johan, Pivarcsi, Andor, Eriksson, Hanna

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Radiotherapy with or without immunotherapy in metastatic melanoma: efficacy and tolerability von Backlund, Ellen, Grozman, Vitali, Egyhazi Brage, Suzanne, Lewensohn, Rolf, Lindberg, Karin, Helgadottir, Hildur

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Association of MITF and other melanosome-related proteins with chemoresistance in melanoma tumors and cell lines von Hertzman Johansson, Carolina, Azimi, Alireza, Frostvik Stolt, Marianne, Shojaee, Seyedmehdi, Wiberg, Henning, Grafström, Eva, Hansson, Johan, Egyházi Brage, Suzanne

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Coexpression of MTH1 and PMS2 Is Associated with Advanced Disease and Disease Progression after Therapy in Melanoma von Das, Ishani, Tuominen, Rainer, Helleday, Thomas, Hansson, Johan, Warpman Berglund, Ulrika, Egyházi Brage, Suzanne

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A biomarker panel predicts recurrence-free survival in ulcerated primary cutaneous melanoma von Falkenius, Johan, Keskitalo, Johanna, Kanter, Lena, Johansson, Hemming, Höiom, Veronica, Hansson, Johan, Egyhazi Brage, Suzanne

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Immune gene expression and response to chemotherapy in advanced breast cancer von Foukakis, Theodoros, Lövrot, John, Matikas, Alexios, Zerdes, Ioannis, Lorent, Julie, Tobin, Nick, Suzuki, Chikako, Brage, Suzanne Egyházi, Carlsson, Lena, Einbeigi, Zakaria, Linderholm, Barbro, Loman, Niklas, Malmberg, Martin, Fernö, Mårten, Skoog, Lambert, Bergh, Jonas, Hatschek, Thomas

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Proliferation and Immune Response Gene Signatures Associated with Clinical Outcome to Immunotherapy and Targeted Therapy in Metastatic Cutaneous Malignant Melanoma von Costa Svedman, Fernanda, Das, Ishani, Tuominen, Rainer, Darai Ramqvist, Eva, Höiom, Veronica, Egyhazi Brage, Suzanne

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