Crystal engineering of the composition of pharmaceutical phases von Walsh, R D Bailey, Bradner, M W, Fleischman, a S, Morales, L A, Moulton, a B, Rodríguez-Hornedo, N, Zaworotko, M J

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Coarctation of a Right Aortic Arch von Maxey, Thomas S., Bradner, Michael W., Reece, T. Brett, Keeling, William B., Kron, Irving L.

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Pharmacological perturbation of CDK9 using selective CDK9 inhibition or degradation von Olson, Calla M, Jiang, Baishan, Erb, Michael A, Liang, Yanke, Doctor, Zainab M, Zhang, Zinan, Zhang, Tinghu, Kwiatkowski, Nicholas, Boukhali, Myriam, Green, Jennifer L, Haas, Wilhelm, Nomanbhoy, Tyzoon, Fischer, Eric S, Young, Richard A, Bradner, James E, Winter, Georg E, Gray, Nathanael S

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Convergent Transcription at Intragenic Super-Enhancers Targets AID-Initiated Genomic Instability von Meng, Fei-Long, Du, Zhou, Federation, Alexander, Hu, Jiazhi, Wang, Qiao, Kieffer-Kwon, Kyong-Rim, Meyers, Robin M., Amor, Corina, Wasserman, Caitlyn R., Neuberg, Donna, Casellas, Rafael, Nussenzweig, Michel C., Bradner, James E., Liu, X. Shirley, Alt, Frederick W.

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NF-κB Directs Dynamic Super Enhancer Formation in Inflammation and Atherogenesis von Brown, Jonathan D., Lin, Charles Y., Duan, Qiong, Griffin, Gabriel, Federation, Alexander J., Paranal, Ronald M., Bair, Steven, Newton, Gail, Lichtman, Andrew H., Kung, Andrew L., Yang, Tianlun, Wang, Hong, Luscinskas, Francis W., Croce, Kevin J., Bradner, James E., Plutzky, Jorge

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MLL3 Is a Haploinsufficient 7q Tumor Suppressor in Acute Myeloid Leukemia von Chen, Chong, Liu, Yu, Rappaport, Amy R., Kitzing, Thomas, Schultz, Nikolaus, Zhao, Zhen, Shroff, Aditya S., Dickins, Ross A., Vakoc, Christopher R., Bradner, James E., Stock, Wendy, LeBeau, Michelle M., Shannon, Kevin M., Kogan, Scott, Zuber, Johannes, Lowe, Scott W.

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Active medulloblastoma enhancers reveal subgroup-specific cellular origins von Lin, Charles Y., Erkek, Serap, Tong, Yiai, Yin, Linlin, Federation, Alexander J., Zapatka, Marc, Haldipur, Parthiv, Kawauchi, Daisuke, Risch, Thomas, Warnatz, Hans-Jörg, Worst, Barbara C., Ju, Bensheng, Orr, Brent A., Zeid, Rhamy, Polaski, Donald R., Segura-Wang, Maia, Waszak, Sebastian M., Jones, David T. W., Kool, Marcel, Hovestadt, Volker, Buchhalter, Ivo, Sieber, Laura, Johann, Pascal, Chavez, Lukas, Gröschel, Stefan, Ryzhova, Marina, Korshunov, Andrey, Chen, Wenbiao, Chizhikov, Victor V., Millen, Kathleen J., Amstislavskiy, Vyacheslav, Lehrach, Hans, Yaspo, Marie-Laure, Eils, Roland, Lichter, Peter, Korbel, Jan O., Pfister, Stefan M., Bradner, James E., Northcott, Paul A.

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Targeting Chromatin Regulators Inhibits Leukemogenic Gene Expression in NPM1 Mutant Leukemia von Kühn, Michael W M, Song, Evelyn, Feng, Zhaohui, Sinha, Amit, Chen, Chun-Wei, Deshpande, Aniruddha J, Cusan, Monica, Farnoud, Noushin, Mupo, Annalisa, Grove, Carolyn, Koche, Richard, Bradner, James E, de Stanchina, Elisa, Vassiliou, George S, Hoshii, Takayuki, Armstrong, Scott A

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Targeting MYCN in neuroblastoma by BET bromodomain inhibition von Puissant, Alexandre, Frumm, Stacey M, Alexe, Gabriela, Bassil, Christopher F, Qi, Jun, Chanthery, Yvan H, Nekritz, Erin A, Zeid, Rhamy, Gustafson, William Clay, Greninger, Patricia, Garnett, Matthew J, McDermott, Ultan, Benes, Cyril H, Kung, Andrew L, Weiss, William A, Bradner, James E, Stegmaier, Kimberly

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Targeting the CoREST complex with dual histone deacetylase and demethylase inhibitors von Kalin, Jay H., Wu, Muzhou, Gomez, Andrea V., Song, Yun, Das, Jayanta, Hayward, Dawn, Adejola, Nkosi, Wu, Mingxuan, Panova, Izabela, Chung, Hye Jin, Kim, Edward, Roberts, Holly J., Roberts, Justin M., Prusevich, Polina, Jeliazkov, Jeliazko R., Roy Burman, Shourya S., Fairall, Louise, Milano, Charles, Eroglu, Abdulkerim, Proby, Charlotte M., Dinkova-Kostova, Albena T., Hancock, Wayne W., Gray, Jeffrey J., Bradner, James E., Valente, Sergio, Mai, Antonello, Anders, Nicole M., Rudek, Michelle A., Hu, Yong, Ryu, Byungwoo, Schwabe, John W. R., Mattevi, Andrea, Alani, Rhoda M., Cole, Philip A.

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CRISPR-Cas9 screen reveals a MYCN-amplified neuroblastoma dependency on EZH2 von Chen, Liying, Alexe, Gabriela, Dharia, Neekesh V, Ross, Linda, Iniguez, Amanda Balboni, Conway, Amy Saur, Wang, Emily Jue, Veschi, Veronica, Lam, Norris, Qi, Jun, Gustafson, W Clay, Nasholm, Nicole, Vazquez, Francisca, Weir, Barbara A, Cowley, Glenn S, Ali, Levi D, Pantel, Sasha, Jiang, Guozhi, Harrington, William F, Lee, Yenarae, Goodale, Amy, Lubonja, Rakela, Krill-Burger, John M, Meyers, Robin M, Tsherniak, Aviad, Root, David E, Bradner, James E, Golub, Todd R, Roberts, Charles Wm, Hahn, William C, Weiss, William A, Thiele, Carol J, Stegmaier, Kimberly

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Response and resistance to BET bromodomain inhibitors in triple-negative breast cancer von Shu, Shaokun, Lin, Charles Y., He, Housheng Hansen, Witwicki, Robert M., Tabassum, Doris P., Roberts, Justin M., Janiszewska, Michalina, Jin Huh, Sung, Liang, Yi, Ryan, Jeremy, Doherty, Ernest, Mohammed, Hisham, Guo, Hao, Stover, Daniel G., Ekram, Muhammad B., Peluffo, Guillermo, Brown, Jonathan, D’Santos, Clive, Krop, Ian E., Dillon, Deborah, McKeown, Michael, Ott, Christopher, Qi, Jun, Ni, Min, Rao, Prakash K., Duarte, Melissa, Wu, Shwu-Yuan, Chiang, Cheng-Ming, Anders, Lars, Young, Richard A., Winer, Eric P., Letai, Antony, Barry, William T., Carroll, Jason S., Long, Henry W., Brown, Myles, Shirley Liu, X., Meyer, Clifford A., Bradner, James E., Polyak, Kornelia

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High-fat diet fuels prostate cancer progression by rewiring the metabolome and amplifying the MYC program von Labbé, David P., Zadra, Giorgia, Yang, Meng, Reyes, Jaime M., Lin, Charles Y., Cacciatore, Stefano, Ebot, Ericka M., Creech, Amanda L., Giunchi, Francesca, Fiorentino, Michelangelo, Elfandy, Habiba, Syamala, Sudeepa, Karoly, Edward D., Alshalalfa, Mohammed, Erho, Nicholas, Ross, Ashley, Schaeffer, Edward M., Gibb, Ewan A., Takhar, Mandeep, Den, Robert B., Lehrer, Jonathan, Karnes, R. Jeffrey, Freedland, Stephen J., Davicioni, Elai, Spratt, Daniel E., Ellis, Leigh, Jaffe, Jacob D., DʼAmico, Anthony V., Kantoff, Philip W., Bradner, James E., Mucci, Lorelei A., Chavarro, Jorge E., Loda, Massimo, Brown, Myles

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Risk of Cardiovascular Events After COVID-19 von Tereshchenko, Larisa G., Bishop, Adam, Fisher-Campbell, Nora, Levene, Jacqueline, Morris, Craig C., Patel, Hetal, Beeson, Erynn, Blank, Jessica A., Bradner, JG N., Coblens, Michelle, Corpron, Jacob W., Davison, Jenna M., Denny, Kathleen, Earp, Mary S., Florea, Simeon, Freeman, Howard, Fuson, Olivia, Guillot, Florian H., Haq, Kazi T., Kim, Morris, Kolseth, Clinton, Krol, Olivia, Lin, Lisa, Litwin, Liat, Malik, Aneeq, Mitchell, Evan, Mohapatra, Aman, Mullen, Cassandra, Nix, Chad D, Oyeyemi, Ayodele, Rutlen, Christine, Tam, Ashley E., Van Buren, Inga, Wallace, Jessica, Khan, Akram

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Combined autophagy and proteasome inhibition: A phase 1 trial of hydroxychloroquine and bortezomib in patients with relapsed/refractory myeloma von Vogl, Dan T, Stadtmauer, Edward A, Tan, Kay-See, Heitjan, Daniel F, Davis, Lisa E, Pontiggia, Laura, Rangwala, Reshma, Piao, Shengfu, Chang, Yunyoung C, Scott, Emma C, Paul, Thomas M, Nichols, Charles W, Porter, David L, Kaplan, Janeen, Mallon, Gayle, Bradner, James E, Amaravadi, Ravi K

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Assessing Vesicular Monoamine Transport and Toxicity Using Fluorescent False Neurotransmitters von Black, Carlie A, Bucher, Meghan L, Bradner, Joshua M, Jonas, Lauren, Igarza, Kenny, Miller, Gary W

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MYB-QKI rearrangements in angiocentric glioma drive tumorigenicity through a tripartite mechanism von Bandopadhayay, Pratiti, Ramkissoon, Lori A, Jain, Payal, Bergthold, Guillaume, Wala, Jeremiah, Zeid, Rhamy, Schumacher, Steven E, Urbanski, Laura, O'Rourke, Ryan, Gibson, William J, Pelton, Kristine, Ramkissoon, Shakti H, Han, Harry J, Zhu, Yuankun, Choudhari, Namrata, Silva, Amanda, Boucher, Katie, Henn, Rosemary E, Kang, Yun Jee, Knoff, David, Paolella, Brenton R, Gladden-Young, Adrianne, Varlet, Pascale, Pages, Melanie, Horowitz, Peleg M, Federation, Alexander, Malkin, Hayley, Tracy, Adam A, Seepo, Sara, Ducar, Matthew, Van Hummelen, Paul, Santi, Mariarita, Buccoliero, Anna Maria, Scagnet, Mirko, Bowers, Daniel C, Giannini, Caterina, Puget, Stephanie, Hawkins, Cynthia, Tabori, Uri, Klekner, Almos, Bognar, Laszlo, Burger, Peter C, Eberhart, Charles, Rodriguez, Fausto J, Hill, D Ashley, Mueller, Sabine, Haas-Kogan, Daphne A, Phillips, Joanna J, Santagata, Sandro, Stiles, Charles D, Bradner, James E, Jabado, Nada, Goren, Alon, Grill, Jacques, Ligon, Azra H, Goumnerova, Liliana, Waanders, Angela J, Storm, Phillip B, Kieran, Mark W, Ligon, Keith L, Beroukhim, Rameen, Resnick, Adam C

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Identification of Regulators of Polyploidization Presents Therapeutic Targets for Treatment of AMKL von Wen, Qiang, Goldenson, Benjamin, Silver, Serena J., Schenone, Monica, Dancik, Vlado, Huang, Zan, Wang, Ling-Zhi, Lewis, Timothy A., An, W. Frank, Li, Xiaoyu, Bray, Mark-Anthony, Thiollier, Clarisse, Diebold, Lauren, Gilles, Laure, Vokes, Martha S., Moore, Christopher B., Bliss-Moreau, Meghan, VerPlank, Lynn, Tolliday, Nicola J., Mishra, Rama, Vemula, Sasidhar, Shi, Jianjian, Wei, Lei, Kapur, Reuben, Lopez, Cécile K., Gerby, Bastien, Ballerini, Paola, Pflumio, Francoise, Gilliland, D. Gary, Goldberg, Liat, Birger, Yehudit, Izraeli, Shai, Gamis, Alan S., Smith, Franklin O., Woods, William G., Taub, Jeffrey, Scherer, Christina A., Bradner, James E., Goh, Boon-Cher, Mercher, Thomas, Carpenter, Anne E., Gould, Robert J., Clemons, Paul A., Carr, Steven A., Root, David E., Schreiber, Stuart L., Stern, Andrew M., Crispino, John D.

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PF00299804, an Irreversible Pan-ERBB Inhibitor, Is Effective in Lung Cancer Models with EGFR and ERBB2 Mutations that Are Resistant to Gefitinib von ENGELMAN, Jeffrey A, ZEJNULLAHU, Kreshnik, ALTHAUS, Irene W, GANDHI, Leena, SHAPIRO, Geoffrey I, NELSON, James M, HEYMACH, John V, MEYERSON, Matthew, WONG, Kwok-Kin, JÄNNE, Pasi A, GALE, Christopher-Michael, LIFSHITS, Eugene, GONZALES, Andrea J, SHIMAMURA, Takeshi, FENG ZHAO, VINCENT, Patrick W, NAUMOV, George N, BRADNER, James E

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Synaptic vesicle glycoprotein 2C enhances vesicular storage of dopamine and counters dopaminergic toxicity von Bucher, Meghan L., Dunn, Amy R., Bradner, Joshua M., Egerton, Kristen Stout, Burkett, James P., Johnson, Michelle A., Miller, Gary W.

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