Biflavonoid-Induced Disruption of Hydrogen Bonds Leads to Amyloid-β Disaggregation von Windsor, Peter K, Plassmeyer, Stephen P, Mattock, Dominic S, Bradfield, Jonathan C, Choi, Erika Y, Miller, 3rd, Bill R, Han, Byung Hee

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A genome-wide meta-analysis of six type 1 diabetes cohorts identifies multiple associated loci von Bradfield, Jonathan P, Qu, Hui-Qi, Wang, Kai, Zhang, Haitao, Sleiman, Patrick M, Kim, Cecilia E, Mentch, Frank D, Qiu, Haijun, Glessner, Joseph T, Thomas, Kelly A, Frackelton, Edward C, Chiavacci, Rosetta M, Imielinski, Marcin, Monos, Dimitri S, Pandey, Rahul, Bakay, Marina, Grant, Struan F A, Polychronakos, Constantin, Hakonarson, Hakon

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Type I IFNs facilitate innate immune control of the opportunistic bacteria Burkholderia cenocepacia in the macrophage cytosol von Dorrington, Michael G, Bradfield, Clinton J, Lack, Justin B, Lin, Bin, Liang, Jonathan J, Starr, Tregei, Ernst, Orna, Gross, Julia L, Sun, Jing, Miller, Alexandra H, Steele-Mortimer, Olivia, Fraser, Iain D C

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Genetic correlations among psychiatric and immune‐related phenotypes based on genome‐wide association data von Tylee, Daniel S., Sun, Jiayin, Hess, Jonathan L., Tahir, Muhammad A., Sharma, Esha, Malik, Rainer, Worrall, Bradford B., Levine, Andrew J., Martinson, Jeremy J., Nejentsev, Sergey, Speed, Doug, Fischer, Annegret, Mick, Eric, Walker, Brian R., Crawford, Andrew, Grant, Struan F. A., Polychronakos, Constantin, Bradfield, Jonathan P., Sleiman, Patrick M. A., Hakonarson, Hakon, Ellinghaus, Eva, Elder, James T., Tsoi, Lam C., Trembath, Richard C., Barker, Jonathan N., Franke, Andre, Dehghan, Abbas, Faraone, Stephen V., Glatt, Stephen J.

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Genetic Discrimination Between LADA and Childhood-Onset Type 1 Diabetes Within the MHC von Mishra, Rajashree, Åkerlund, Mikael, Cousminer, Diana L, Ahlqvist, Emma, Bradfield, Jonathan P, Chesi, Alessandra, Hodge, Kenyaita M, Guy, Vanessa C, Brillon, David J, Pratley, Richard E, Rickels, Michael R, Vella, Adrian, Ovalle, Fernando, Harris, Ronald I, Melander, Olle, Varvel, Stephen, Hakonarson, Hakon, Froguel, Phillippe, Lonsdale, John T, Mauricio, Didac, Schloot, Nanette C, Khunti, Kamlesh, Greenbaum, Carla J, Yderstræde, Knud B, Tuomi, Tiinamaija, Voight, Benjamin F, Schwartz, Stanley, Boehm, Bernhard O, Groop, Leif, Leslie, Richard David, Grant, Struan F A

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Transcriptional Basis for Rhythmic Control of Hunger and Metabolism within the AgRP Neuron von Cedernaes, Jonathan, Huang, Wenyu, Ramsey, Kathryn Moynihan, Waldeck, Nathan, Cheng, Lei, Marcheva, Biliana, Omura, Chiaki, Kobayashi, Yumiko, Peek, Clara Bien, Levine, Daniel C., Dhir, Ravindra, Awatramani, Raj, Bradfield, Christopher A., Wang, Xiaozhong A., Takahashi, Joseph S., Mokadem, Mohamad, Ahima, Rexford S., Bass, Joseph

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High-resolution mapping and analysis of copy number variations in the human genome: a data resource for clinical and research applications von Shaikh, Tamim H, Gai, Xiaowu, Perin, Juan C, Glessner, Joseph T, Xie, Hongbo, Murphy, Kevin, O'Hara, Ryan, Casalunovo, Tracy, Conlin, Laura K, D'Arcy, Monica, Frackelton, Edward C, Geiger, Elizabeth A, Haldeman-Englert, Chad, Imielinski, Marcin, Kim, Cecilia E, Medne, Livija, Annaiah, Kiran, Bradfield, Jonathan P, Dabaghyan, Elvira, Eckert, Andrew, Onyiah, Chioma C, Ostapenko, Svetlana, Otieno, F George, Santa, Erin, Shaner, Julie L, Skraban, Robert, Smith, Ryan M, Elia, Josephine, Goldmuntz, Elizabeth, Spinner, Nancy B, Zackai, Elaine H, Chiavacci, Rosetta M, Grundmeier, Robert, Rappaport, Eric F, Grant, Struan F A, White, Peter S, Hakonarson, Hakon

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Relative contribution of type 1 and type 2 diabetes loci to the genetic etiology of adult-onset, non-insulin-requiring autoimmune diabetes von Mishra, Rajashree, Chesi, Alessandra, Cousminer, Diana L, Hawa, Mohammad I, Bradfield, Jonathan P, Hodge, Kenyaita M, Guy, Vanessa C, Hakonarson, Hakon, Mauricio, Didac, Schloot, Nanette C, Yderstræde, Knud B, Voight, Benjamin F, Schwartz, Stanley, Boehm, Bernhard O, Leslie, Richard David, Grant, Struan F A

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First Genome-Wide Association Study of Latent Autoimmune Diabetes in Adults Reveals Novel Insights Linking Immune and Metabolic Diabetes von Cousminer, Diana L, Ahlqvist, Emma, Mishra, Rajashree, Andersen, Mette K, Chesi, Alessandra, Hawa, Mohammad I, Davis, Asa, Hodge, Kenyaita M, Bradfield, Jonathan P, Zhou, Kaixin, Guy, Vanessa C, Åkerlund, Mikael, Wod, Mette, Fritsche, Lars G, Vestergaard, Henrik, Snyder, James, Højlund, Kurt, Linneberg, Allan, Käräjämäki, Annemari, Brandslund, Ivan, Kim, Cecilia E, Witte, Daniel, Sørgjerd, Elin Pettersen, Brillon, David J, Pedersen, Oluf, Beck-Nielsen, Henning, Grarup, Niels, Pratley, Richard E, Rickels, Michael R, Vella, Adrian, Ovalle, Fernando, Melander, Olle, Harris, Ronald I, Varvel, Stephen, Grill, Valdemar E R, Hakonarson, Hakon, Froguel, Philippe, Lonsdale, John T, Mauricio, Didac, Schloot, Nanette C, Khunti, Kamlesh, Greenbaum, Carla J, Åsvold, Bjørn Olav, Yderstræde, Knud B, Pearson, Ewan R, Schwartz, Stanley, Voight, Benjamin F, Hansen, Torben, Tuomi, Tiinamaija, Boehm, Bernhard O, Groop, Leif, Leslie, R David, Grant, Struan F A

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Duplication of the SLIT3 locus on 5q35.1 predisposes to major depressive disorder von Glessner, Joseph T, Wang, Kai, Sleiman, Patrick M A, Zhang, Haitao, Kim, Cecilia E, Flory, James H, Bradfield, Jonathan P, Imielinski, Marcin, Frackelton, Edward C, Qiu, Haijun, Mentch, Frank, Grant, Struan F A, Hakonarson, Hakon

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Biphasic JNK signaling reveals distinct MAP3K complexes licensing inflammasome formation and pyroptosis von Bradfield, Clinton J., Liang, Jonathan J., Ernst, Orna, John, Sinu P., Sun, Jing, Ganesan, Sundar, de Jesus, Adriana A., Bryant, Clare E., Goldbach-Mansky, Raphaela, Fraser, Iain D. C.

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Association analysis of the FTO gene with obesity in children of Caucasian and African ancestry reveals a common tagging SNP von Grant, Struan F A, Li, Mingyao, Bradfield, Jonathan P, Kim, Cecilia E, Annaiah, Kiran, Santa, Erin, Glessner, Joseph T, Casalunovo, Tracy, Frackelton, Edward C, Otieno, F George, Shaner, Julie L, Smith, Ryan M, Imielinski, Marcin, Eckert, Andrew W, Chiavacci, Rosetta M, Berkowitz, Robert I, Hakonarson, Hakon

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Common variations in BARD1 influence susceptibility to high-risk neuroblastoma von Devoto, Marcella, Hakonarson, Hakon, Maris, John M, Capasso, Mario, Hou, Cuiping, Asgharzadeh, Shahab, Glessner, Joseph T, Attiyeh, Edward F, Mosse, Yael P, Kim, Cecilia, Diskin, Sharon J, Cole, Kristina A, Bosse, Kristopher, Diamond, Maura, Laudenslager, Marci, Winter, Cynthia, Bradfield, Jonathan P, Scott, Richard H, Jagannathan, Jayanti, Garris, Maria, McConville, Carmel, London, Wendy B, Seeger, Robert C, Grant, Struan F A, Li, Hongzhe, Rahman, Nazneen, Rappaport, Eric

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Diverse Genome-wide Association Studies Associate the IL12/IL23 Pathway with Crohn Disease von Wang, Kai, Zhang, Haitao, Kugathasan, Subra, Annese, Vito, Bradfield, Jonathan P., Russell, Richard K., Sleiman, Patrick M.A., Imielinski, Marcin, Glessner, Joseph, Hou, Cuiping, Wilson, David C., Walters, Thomas, Kim, Cecilia, Frackelton, Edward C., Lionetti, Paolo, Barabino, Arrigo, Van Limbergen, Johan, Guthery, Stephen, Denson, Lee, Piccoli, David, Li, Mingyao, Dubinsky, Marla, Silverberg, Mark, Griffiths, Anne, Grant, Struan F.A., Satsangi, Jack, Baldassano, Robert, Hakonarson, Hakon

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genome-wide association study identifies KIAA0350 as a type 1 diabetes gene von HAKONARSON, Hakon, GRANT, Struan F. A, LAWSON, Margaret L, ROBINSON, Luke J, SKRABAN, Robert, YANG LU, CHIAVACCI, Rosetta M, STANLEY, Charles A, KIRSCH, Susan E, RAPPAPORT, Eric F, ORANGE, Jordan S, MONOS, Dimitri S, BRADFIELD, Jonathan P, DEVOTO, Marcella, QU, Hui-Qi, POLYCHRONAKOS, Constantin, MARCHAND, Luc, KIM, Cecilia E, GLESSNER, Joseph T, GRABS, Rosemarie, CASALUNOVO, Tracy, TABACK, Shayne P, FRACKELTON, Edward C

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A Genome-Wide Association Study Identifies a Locus for Nonsyndromic Cleft Lip with or without Cleft Palate on 8q24 von Grant, Struan F.A., PhD, Wang, Kai, PhD, Zhang, Haitao, PhD, Glaberson, Wendy, BA, Annaiah, Kiran, MSc, Kim, Cecilia E., BA, Bradfield, Jonathan P., BS, Glessner, Joseph T., MSc, Thomas, Kelly A., BA, Garris, Maria, BA, Frackelton, Edward C., BA, Otieno, F. George, MSc, Chiavacci, Rosetta M., BSN, Nah, Hyun-Duck, PhD, Kirschner, Richard E., MD, Hakonarson, Hakon, MD, PhD

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Cis-regulatory architecture of human ESC-derived hypothalamic neuron differentiation aids in variant-to-gene mapping of relevant complex traits von Pahl, Matthew C., Doege, Claudia A., Hodge, Kenyaita M., Littleton, Sheridan H., Leonard, Michelle E., Lu, Sumei, Rausch, Rick, Pippin, James A., De Rosa, Maria Caterina, Basak, Alisha, Bradfield, Jonathan P., Hammond, Reza K., Boehm, Keith, Berkowitz, Robert I., Lasconi, Chiara, Su, Chun, Chesi, Alessandra, Johnson, Matthew E., Wells, Andrew D., Voight, Benjamin F., Leibel, Rudolph L., Cousminer, Diana L., Grant, Struan F. A.

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2011 ACCF/AHA/HRS Focused Update on the Management of Patients With Atrial Fibrillation (Updating the 2006 Guideline): A Report of the American College of Cardiology Foundation/Ame... von WANN, L. Samuel, CURTIS, Anne B, STEVENSON, William G, TRACY, Cynthia M, JANUARY, Craig T, ELLENBOGEN, Kenneth A, LOWE, James E, ESTES, N. A. Mark, PAGE, Richard L, EZEKOWITZ, Michael D, SLOTWINER, David J, JACKMAN, Warren M

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Strong synaptic transmission impact by copy number variations in schizophrenia von Glessner, Joseph T., Reilly, Muredach P., Kim, Cecilia E., Takahashi, Nagahide, Albano, Anthony, Hou, Cuiping, Bradfield, Jonathan P., Zhang, Haitao, Sleiman, Patrick M. A., Flory, James H., Imielinski, Marcin, Frackelton, Edward C., Chiavacci, Rosetta, Thomas, Kelly A., Garris, Maria, Otieno, Frederick G., Davidson, Michael, Weiser, Mark, Reichenberg, Abraham, Davis, Kenneth L., Friedman, Joseph I., Cappola, Thomas P., Margulies, Kenneth B., Rader, Daniel J., Grant, Struan F. A., Buxbaum, Joseph D., Gur, Raquel E., Hakonarson, Hakon, Lupski, James R.

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Correction: Type I IFNs facilitate innate immune control of the opportunistic bacteria Burkholderia cenocepacia in the macrophage cytosol von Dorrington, Michael G, Bradfield, Clinton J, Lack, Justin B, Lin, Bin, John, Sinu P, Liang, Jonathan J, Starr, Tregei, Ernst, Orna, Gross, Julia L, Sun, Jing, Miller, Alexandra H, Steele-Mortimer, Olivia, Fraser, Iain D. C

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