Methionine restriction activates the retrograde response and confers both stress tolerance and lifespan extension to yeast, mouse and human cells von Johnson, Jay E, Johnson, F Brad

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TERRA G-quadruplex RNA interaction with TRF2 GAR domain is required for telomere integrity von Mei, Yang, Deng, Zhong, Vladimirova, Olga, Gulve, Nitish, Johnson, F. Brad, Drosopoulos, William C., Schildkraut, Carl L., Lieberman, Paul M.

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Histone H4 lysine 16 acetylation regulates cellular lifespan von Dang, Weiwei, Steffen, Kristan K, Perry, Rocco, Dorsey, Jean A, Johnson, F. Brad, Shilatifard, Ali, Kaeberlein, Matt, Kennedy, Brian K, Berger, Shelley L

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Determinants of response and resistance to CD19 chimeric antigen receptor (CAR) T cell therapy of chronic lymphocytic leukemia von Fraietta, Joseph A., Lacey, Simon F., Orlando, Elena J., Pruteanu-Malinici, Iulian, Gohil, Mercy, Lundh, Stefan, Boesteanu, Alina C., Wang, Yan, O’Connor, Roddy S., Hwang, Wei-Ting, Pequignot, Edward, Ambrose, David E., Zhang, Changfeng, Wilcox, Nicholas, Bedoya, Felipe, Dorfmeier, Corin, Chen, Fang, Tian, Lifeng, Parakandi, Harit, Gupta, Minnal, Young, Regina M., Johnson, F. Brad, Kulikovskaya, Irina, Liu, Li, Xu, Jun, Kassim, Sadik H., Davis, Megan M., Levine, Bruce L., Frey, Noelle V., Siegel, Donald L., Huang, Alexander C., Wherry, E. John, Bitter, Hans, Brogdon, Jennifer L., Porter, David L., June, Carl H., Melenhorst, J. Joseph

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Aging alters bone-fat reciprocity by shifting in vivo mesenchymal precursor cell fate towards an adipogenic lineage von Singh, Lakshman, Brennan, Tracy A, Russell, Elizabeth, Kim, Jung-Hoon, Chen, Qijun, Brad Johnson, F, Pignolo, Robert J

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Dysregulation of the epigenetic landscape of normal aging in Alzheimer’s disease von Nativio, Raffaella, Donahue, Greg, Berson, Amit, Lan, Yemin, Amlie-Wolf, Alexandre, Tuzer, Ferit, Toledo, Jon B., Gosai, Sager J., Gregory, Brian D., Torres, Claudio, Trojanowski, John Q., Wang, Li-San, Johnson, F. Brad, Bonini, Nancy M., Berger, Shelley L.

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DNA-Damage-Induced Type I Interferon Promotes Senescence and Inhibits Stem Cell Function von Yu, Qiujing, Katlinskaya, Yuliya V., Carbone, Christopher J., Zhao, Bin, Katlinski, Kanstantsin V., Zheng, Hui, Guha, Manti, Li, Ning, Chen, Qijun, Yang, Ting, Lengner, Christopher J., Greenberg, Roger A., Johnson, F. Brad, Fuchs, Serge Y.

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HMGB2 orchestrates the chromatin landscape of senescence-associated secretory phenotype gene loci von Aird, Katherine M, Iwasaki, Osamu, Kossenkov, Andrew V, Tanizawa, Hideki, Fatkhutdinov, Nail, Bitler, Benjamin G, Le, Linh, Alicea, Gretchen, Yang, Ting-Lin, Johnson, F Brad, Noma, Ken-Ichi, Zhang, Rugang

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Role for G-Quadruplex RNA Binding by Epstein-Barr Virus Nuclear Antigen 1 in DNA Replication and Metaphase Chromosome Attachment von NORSEEN, Julie, BRAD JOHNSON, F, LIEBERMAN, Paul M

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A regulatory loop connecting WNT signaling and telomere capping: possible therapeutic implications for dyskeratosis congenita von Fernandez, Rafael Jesus, Johnson, F. Brad

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Metabolic and Phenotypic Differences between Mice Producing a Werner Syndrome Helicase Mutant Protein and Wrn Null Mice von Aumailley, Lucie, Garand, Chantal, Dubois, Marie Julie, Johnson, F Brad, Marette, André, Lebel, Michel

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Enhancing a Wnt-Telomere Feedback Loop Restores Intestinal Stem Cell Function in a Human Organotypic Model of Dyskeratosis Congenita von Woo, Dong-Hun, Chen, Qijun, Yang, Ting-Lin B., Glineburg, M. Rebecca, Hoge, Carla, Leu, Nicolae A., Johnson, F. Brad, Lengner, Christopher J.

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Inactivation of Yeast Isw2 Chromatin Remodeling Enzyme Mimics Longevity Effect of Calorie Restriction via Induction of Genotoxic Stress Response von Dang, Weiwei, Sutphin, George L., Dorsey, Jean A., Otte, Gabriel L., Cao, Kajia, Perry, Rocco M., Wanat, Jennifer J., Saviolaki, Dimitra, Murakami, Christopher J., Tsuchiyama, Scott, Robison, Brett, Gregory, Brian D., Vermeulen, Michiel, Shiekhattar, Ramin, Johnson, F. Brad, Kennedy, Brian K., Kaeberlein, Matt, Berger, Shelley L.

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Changes in the Transcriptome of Human Astrocytes Accompanying Oxidative Stress-Induced Senescence von Crowe, Elizabeth P, Tuzer, Ferit, Gregory, Brian D, Donahue, Greg, Gosai, Sager J, Cohen, Justin, Leung, Yuk Y, Yetkin, Emre, Nativio, Raffaella, Wang, Li-San, Sell, Christian, Bonini, Nancy M, Berger, Shelley L, Johnson, F Brad, Torres, Claudio

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TERRA and the histone methyltransferase Dot1 cooperate to regulate senescence in budding yeast von Wanat, Jennifer J, Logsdon, Glennis A, Driskill, Jordan H, Deng, Zhong, Lieberman, Paul M, Johnson, F Brad

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GSK3 inhibition rescues growth and telomere dysfunction in dyskeratosis congenita iPSC-derived type II alveolar epithelial cells von Fernandez, 3rd, Rafael Jesus, Gardner, Zachary J G, Slovik, Katherine J, Liberti, Derek C, Estep, Katrina N, Yang, Wenli, Chen, Qijun, Santini, Garrett T, Perez, Javier V, Root, Sarah, Bhatia, Ranvir, Tobias, John W, Babu, Apoorva, Morley, Michael P, Frank, David B, Morrisey, Edward E, Lengner, Christopher J, Johnson, F Brad

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Computational detection and analysis of sequences with duplex-derived interstrand G-quadruplex forming potential von Cao, Kajia, Ryvkin, Paul, Brad Johnson, F.

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An Expanded Role for HLA Genes: HLA-B Encodes a microRNA that Regulates IgA and Other Immune Response Transcripts von Chitnis, Nilesh, Clark, Peter M, Kamoun, Malek, Stolle, Catherine, Brad Johnson, F, Monos, Dimitri S

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Impacts of radiation exposure, hindlimb unloading, and recovery on murine skeletal muscle cell telomere length von Tichy, Elisia D., Lee, Ji-Hyung, Li, Grant, Estep, Katrina N., Brad Johnson, F., Mourkioti, Foteini

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Mutual reinforcement between telomere capping and canonical Wnt signalling in the intestinal stem cell niche von Yang, Ting-Lin B., Chen, Qijun, Deng, Jennifer T., Jagannathan, Geetha, Tobias, John W., Schultz, David C., Wang, Shan, Lengner, Christopher J., Rustgi, Anil K., Lynch, John P., Johnson, F. Brad

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