Web-TCGA: an online platform for integrated analysis of molecular cancer data sets von Deng, Mario, Brägelmann, Johannes, Schultze, Joachim L, Perner, Sven

Volltext

Recurrent HNSCC Harbor an Immunosuppressive Tumor Immune Microenvironment Suggesting Successful Tumor Immune Evasion von Watermann, Christian, Pasternack, Helen, Idel, Christian, Ribbat-Idel, Julika, Braegelmann, Johannes, Kuppler, Patrick, Offermann, Anne, Jonigk, Danny, Kuehnel, Mark, Schroeck, Andreas, Dreyer, Eva, Rosero, Christian, Nathansen, Jacqueline, Dubrovska, Anna, Tharun, Lars, Kirfel, Jutta, Wollenberg, Barbara, Perner, Sven, Krupar, Rosemarie

Volltext

FirebrowseR: an R client to the Broad Institute’s Firehose Pipeline von Deng, Mario, Brägelmann, Johannes, Kryukov, Ivan, Saraiva-Agostinho, Nuno, Perner, Sven

Volltext

Integrative and comparative genomic analysis of HPV-positive and HPV-negative head and neck squamous cell carcinomas von Seiwert, Tanguy Y, Zuo, Zhixiang, Keck, Michaela K, Khattri, Arun, Pedamallu, Chandra S, Stricker, Thomas, Brown, Christopher, Pugh, Trevor J, Stojanov, Petar, Cho, Juok, Lawrence, Michael S, Getz, Gad, Brägelmann, Johannes, DeBoer, Rebecca, Weichselbaum, Ralph R, Langerman, Alexander, Portugal, Louis, Blair, Elizabeth, Stenson, Kerstin, Lingen, Mark W, Cohen, Ezra E W, Vokes, Everett E, White, Kevin P, Hammerman, Peter S

Volltext

Integrative analysis of head and neck cancer identifies two biologically distinct HPV and three non-HPV subtypes von Keck, Michaela K, Zuo, Zhixiang, Khattri, Arun, Stricker, Thomas P, Brown, Christopher D, Imanguli, Matin, Rieke, Damian, Endhardt, Katharina, Fang, Petra, Brägelmann, Johannes, DeBoer, Rebecca, El-Dinali, Mohamed, Aktolga, Serdal, Lei, Zhengdeng, Tan, Patrick, Rozen, Steve G, Salgia, Ravi, Weichselbaum, Ralph R, Lingen, Mark W, Story, Michael D, Ang, K Kian, Cohen, Ezra E W, White, Kevin P, Vokes, Everett E, Seiwert, Tanguy Y

Volltext

Family matters: How MYC family oncogenes impact small cell lung cancer von Brägelmann, Johannes, Böhm, Stefanie, Guthrie, Matthew R., Mollaoglu, Gurkan, Oliver, Trudy G., Sos, Martin L.

Volltext

Insight into Targeting Exon20 Insertion Mutations of the Epidermal Growth Factor Receptor with Wild Type-Sparing Inhibitors von Lategahn, Jonas, Tumbrink, Hannah L., Schultz-Fademrecht, Carsten, Heimsoeth, Alena, Werr, Lisa, Niggenaber, Janina, Keul, Marina, Parmaksiz, Fatma, Baumann, Matthias, Menninger, Sascha, Zent, Eldar, Landel, Ina, Weisner, Jörn, Jeyakumar, Kirujan, Heyden, Leonie, Russ, Nicole, Müller, Fabienne, Lorenz, Carina, Brägelmann, Johannes, Spille, Inga, Grabe, Tobias, Müller, Matthias P., Heuckmann, Johannes M., Klebl, Bert M., Nussbaumer, Peter, Sos, Martin L., Rauh, Daniel

Volltext

Performance of the CHARGE-AF risk model for incident atrial fibrillation in the EPIC Norfolk cohort von Pfister, Roman, Brägelmann, Johannes, Michels, Guido, Wareham, Nick J, Luben, Robert, Khaw, Kay-Tee

Volltext

Predicting the next move: tracking the complexity of lung cancer evolution and metastasis von Lorenz, Carina, Hillmer, Axel M., Brägelmann, Johannes

Volltext

Next-generation lung cancer pathology: Development and validation of diagnostic and prognostic algorithms von Kludt, Carina, Wang, Yuan, Ahmad, Waleed, Bychkov, Andrey, Fukuoka, Junya, Gaisa, Nadine, Kühnel, Mark, Jonigk, Danny, Pryalukhin, Alexey, Mairinger, Fabian, Klein, Franziska, Schultheis, Anne Maria, Seper, Alexander, Hulla, Wolfgang, Brägelmann, Johannes, Michels, Sebastian, Klein, Sebastian, Quaas, Alexander, Büttner, Reinhard, Tolkach, Yuri

Volltext

MYC paralog-dependent apoptotic priming orchestrates a spectrum of vulnerabilities in small cell lung cancer von Dammert, Marcel A., Brägelmann, Johannes, Olsen, Rachelle R., Böhm, Stefanie, Monhasery, Niloufar, Whitney, Christopher P., Chalishazar, Milind D., Tumbrink, Hannah L., Guthrie, Matthew R., Klein, Sebastian, Ireland, Abbie S., Ryan, Jeremy, Schmitt, Anna, Marx, Annika, Ozretić, Luka, Castiglione, Roberta, Lorenz, Carina, Jachimowicz, Ron D., Wolf, Elmar, Thomas, Roman K., Poirier, John T., Büttner, Reinhard, Sen, Triparna, Byers, Lauren A., Reinhardt, H. Christian, Letai, Anthony, Oliver, Trudy G., Sos, Martin L.

Volltext

Somatic rearrangements causing oncogenic ectodomain deletions of FGFR1 in squamous cell lung cancer von Malchers, Florian, Nogova, Lucia, van Attekum, Martijn Ha, Maas, Lukas, Brägelmann, Johannes, Bartenhagen, Christoph, Girard, Luc, Bosco, Graziella, Dahmen, Ilona, Michels, Sebastian, Weeden, Clare E, Scheel, Andreas H, Meder, Lydia, Golfmann, Kristina, Schuldt, Philipp, Siemanowski, Janna, Rehker, Jan, Merkelbach-Bruse, Sabine, Menon, Roopika, Gautschi, Oliver, Heuckmann, Johannes M, Brambilla, Elisabeth, Asselin-Labat, Marie-Liesse, Persigehl, Thorsten, Minna, John D, Walczak, Henning, Ullrich, Roland T, Fischer, Matthias, Reinhardt, Hans Christian, Wolf, Jürgen, Büttner, Reinhard, Peifer, Martin, George, Julie, Thomas, Roman K

Volltext

CDK19 as a Potential HPV-Independent Biomarker for Recurrent Disease in HNSCC von Paulsen, Finn-Ole, Idel, Christian, Ribbat-Idel, Julika, Kuppler, Patrick, Klapper, Luise, Rades, Dirk, Bruchhage, Karl-Ludwig, Wollenberg, Barbara, Braegelmann, Johannes, Perner, Sven, Offermann, Anne

Volltext

Implication of the Receptor Tyrosine Kinase AXL in Head and Neck Cancer Progression von von Mässenhausen, Anne, Brägelmann, Johannes, Billig, Hannah, Thewes, Britta, Queisser, Angela, Vogel, Wenzel, Kristiansen, Glen, Schröck, Andreas, Bootz, Friedrich, Brossart, Peter, Kirfel, Jutta, Perner, Sven

Volltext

Targeting DDR2 in head and neck squamous cell carcinoma with dasatinib von von Mässenhausen, Anne, Sanders, Christine, Brägelmann, Johannes, Konantz, Martina, Queisser, Angela, Vogel, Wenzel, Kristiansen, Glen, Duensing, Stefan, Schröck, Andreas, Bootz, Friedrich, Brossart, Peter, Kirfel, Jutta, Lengerke, Claudia, Perner, Sven

Volltext

Structural Alterations of MET Trigger Response to MET Kinase Inhibition in Lung Adenocarcinoma Patients von Plenker, Dennis, Bertrand, Miriam, de Langen, Adrianus J, Riedel, Richard, Lorenz, Carina, Scheel, Andreas H, Müller, Judith, Brägelmann, Johannes, Daßler-Plenker, Juliane, Kobe, Carsten, Persigehl, Thorsten, Kluge, Alexander, Wurdinger, Thomas, Schellen, Pepijn, Hartmann, Gunther, Zacherle, Tobias, Menon, Roopika, Thunnissen, Erik, Büttner, Reinhard, Griesinger, Frank, Wolf, Jürgen, Heukamp, Lukas, Sos, Martin L, Heuckmann, Johannes M

Volltext

Benchmark of screening markers for KEAP1/NFE2L2 mutations and joint analysis with the K1N2-score von Arolt, Christoph, Scheel, Andreas H., Dugan, Margaret, Wild, Robert, Richartz, Vanessa, Holz, Barbara, Brägelmann, Johannes, Wagener-Ryczek, Svenja, Merkelbach-Bruse, Sabine, Wolf, Juergen, Buettner, Reinhard, Catanzariti, Luigi, Scheffler, Matthias, Hillmer, Axel M.

Volltext

Pan-Cancer Analysis of the Mediator Complex Transcriptome Identifies CDK19 and CDK8 as Therapeutic Targets in Advanced Prostate Cancer von Brägelmann, Johannes, Klümper, Niklas, Offermann, Anne, von Mässenhausen, Anne, Böhm, Diana, Deng, Mario, Queisser, Angela, Sanders, Christine, Syring, Isabella, Merseburger, Axel S, Vogel, Wenzel, Sievers, Elisabeth, Vlasic, Ignacija, Carlsson, Jessica, Andrén, Ove, Brossart, Peter, Duensing, Stefan, Svensson, Maria A, Adler, David, Kirfel, Jutta, Perner, Sven

Volltext

RON (MST1R) is a novel prognostic marker and therapeutic target for gastroesophageal adenocarcinoma von Catenacci, Daniel V.T., Cervantes, Gustavo, Yala, Soheil, Nelson, Erik A., El-Hashani, Essam, Kanteti, Rajani, El Dinali, Mohamed, Hasina, Rifat, Brägelmann, Johannes, Seiwert, Tanguy, Sanicola, Michele, Henderson, Les, Grushko, Tatyana A., Olopade, Olufunmilayo, Karrison, Theodore, Bang, Yung-Jue, Kim, Woo Ho, Tretiakova, Maria, Vokes, Everett, Frank, David A., Kindler, Hedy L., Huet, Heather, Salgia, Ravi

Volltext

Tripartite antigen-agnostic combination immunotherapy cures established poorly immunogenic tumors von Borchmann, Sven, Selenz, Carolin, Lohmann, Mia, Ludwig, Hanna, Gassa, Asmae, Brägelmann, Johannes, Lohneis, Philipp, Meder, Lydia, Mattlener, Julia, Breid, Sara, Nill, Marieke, Fassunke, Jana, Wisdom, Amy J., Compes, Anik, Gathof, Birgit, Alakus, Hakan, Kirsch, David, Hekmat, Khosro, Büttner, Reinhard, Reinhardt, H. Christian, Hallek, Michael, Ullrich, Roland T.

Volltext