Structural Determinants for Small-Molecule Activation of Skeletal Muscle AMPK α2β2γ1 by the Glucose Importagog SC4 von Ngoei, Kevin R.W., Langendorf, Christopher G., Ling, Naomi X.Y., Hoque, Ashfaqul, Varghese, Swapna, Camerino, Michelle A., Walker, Scott R., Bozikis, Ylva E., Dite, Toby A., Ovens, Ashley J., Smiles, William J., Jacobs, Roxane, Huang, He, Parker, Michael W., Scott, John W., Rider, Mark H., Foitzik, Richard C., Kemp, Bruce E., Baell, Jonathan B., Oakhill, Jonathan S.

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Discovery of a highly potent, selective, orally bioavailable inhibitor of KAT6A/B histone acetyltransferases with efficacy against KAT6A-high ER+ breast cancer von Sharma, Shikhar, Chung, Chi-Yeh, Uryu, Sean, Petrovic, Jelena, Cao, Joan, Rickard, Amanda, Nady, Nataliya, Greasley, Samantha, Johnson, Eric, Brodsky, Oleg, Khan, Showkhin, Wang, Hui, Wang, Zhenxiong, Zhang, Yong, Tsaparikos, Konstantinos, Chen, Lei, Mazurek, Anthony, Lapek, John, Kung, Pei-Pei, Sutton, Scott, Richardson, Paul F., Greenwald, Eric C., Yamazaki, Shinji, Jones, Rhys, Maegley, Karen A., Bingham, Patrick, Lam, Hieu, Stupple, Alexandra E., Kamal, Aileen, Chueh, Anderly, Cuzzupe, Anthony, Morrow, Benjamin J., Ren, Bin, Carrasco-Pozo, Catalina, Tan, Chin Wee, Bhuva, Dharmesh D., Allan, Elizabeth, Surgenor, Elliot, Vaillant, François, Pehlivanoglu, Havva, Falk, Hendrik, Whittle, James R., Newman, Janet, Cursons, Joseph, Doherty, Judy P., White, Karen L., MacPherson, Laura, Devlin, Mark, Dennis, Matthew L., Hattarki, Meghan K., De Silva, Melanie, Camerino, Michelle A., Butler, Miriam S., Dolezal, Olan, Pilling, Patricia, Foitzik, Richard, Stupple, Paul A., Lagiakos, H. Rachel, Walker, Scott R., Hediyeh-Zadeh, Soroor, Nuttall, Stewart, Spall, Sukhdeep K., Charman, Susan A., Connor, Theresa, Peat, Thomas S., Avery, Vicky M., Bozikis, Ylva E., Yang, Yuqing, Zhang, Ming, Monahan, Brendon J., Voss, Anne K., Thomas, Tim, Street, Ian P., Dawson, Sarah-Jane, Dawson, Mark A., Lindeman, Geoffrey J., Davis, Melissa J., Visvader, Jane E., Paul, Thomas A.

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Abstract 1130: First-in-class KAT6A/KAT6B inhibitor CTx-648 (PF-9363) demonstrates potent anti-tumor activity in ER+ breast cancer with KAT6A dysregulation von Sharma, Shikhar, Chung, Jay, Uryu, Sean, Rickard, Amanda, Nady, Natalie, Khan, Showkhin, Wang, Zhenxiong, Zhang, Yong, Zhang, Haikuo, Kung, Pei-Pei, Greenwald, Eric, Maegley, Karen, Bingham, Patrick, Lam, Hieu, Bozikis, Ylva E., Falk, Hendrik, Allan, Elizabeth, Avery, Vicky M., Butler, Miriam S., Camerino, Michelle A., Carrasco-Pozo, Catalina, Charman, Susan A., Davis, Melissa J., Dawson, Mark A., Sarah-Jane, Dawson, de Silva, Melanie, Dennis, Matthew L., Dolezal, Olan, Lagiakos, Rachel, Lindeman, Geoffrey J., MacPherson, Laura, Nuttall, Stewart, Peat, Thomas S., Ren, Bin, Stupple, Alexandra E., Surgenor, Elliot, Tan, Chin Wee, Thomas, Tim, Visvader, Jane E., Voss, Anne K., Vaillant, Francois, White, Karen L., Whittle, James, Yang, Yuqing, Hediyeh-Zadeh, Soroor, Stupple, Paul A., Street, Ian P., Monahan, Brendon J., Paul, Thomas

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Abstract 5371: PRMT5 inhibitors as novel treatment for cancers von Falk, Hendrik, Foitzik, Richard C., Allan, Elizabeth, deSilva, Melanie, Yang, Hong, Bozikis, Ylva E., Nikac, Marica, Walker, Scott R., Camerino, Michelle A., Morrow, Ben J., Stupple, Alexandra E., Lagiakos, Rachel, Pinson, Jo-Anne, Lessene, Romina, Kersten, Wilhelmus JA, Ganame, Danny G., Holmes, Ian P., Lunniss, Gill E., Chung, Matthew, Hermans, Stefan J., Parker, Michael W., Thistlethwaite, Alison, White, Karen, Charman, Susan A., Monahan, Brendon J., Pilling, Patricia, Grusovin, Julian, Peat, Thomas S., Sonderegger, Stefan, Toulmin, Emma, Jane, Stephen M., Curtis, David J., Stupple, Paul A., Street, Ian P.

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COMPOUND von MORROW BENJAMIN J, BOZIKIS YLVA E B, LAGIAKOS HELEN R, WALKER SCOTT R, FOITZIK RICHARD C, CAMERINO MICHELLE A, HEMLEY CATHERINE F, STUPPLE PAUL A

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Compuestos von FOITZIK, Richard, HEMLEY, Catherine, STUPPLE, Paul, MORROW, Benjamin, CAMERINO, Michelle, WALKER, Scott, LAGIAKOS, Helen, BOZIKIS, Ylva

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Derivados de benzotiofeno, tienopiridina y tienopirimidina para la modulación de STING von CAMERINO, Michelle Ang, HUBERT, Jonathan Grant, STUPPLE, Paul Anthony, CUZZUPE, Anthony Nicholas, MORROW, Benjamin Joseph, BOZIKIS, Ylva Elisabet Bergman

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Derivados de benzisoxazol sulfonamida von CAMERINO, Michelle Ang, KUMPF, Robert Arnold, SUTTON, Scott Channing, STUPPLE, Paul Anthony, BRODSKY, Oleg, KUNG, Pei-Pei, GREASLEY, Samantha Elizabeth, HOFFMAN, Robert Louis, RICHARDSON, Paul Francis, BOZIKIS, Ylva Elisabet Bergman

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N-BENZISOXAZOLIL SULFONAMIDAS COMO INHIBIDORES DE KAT von Lagiakos, Helen, Walker, Scott, Morrow, Benjamin, Stupple, Paul, Camerino, Michelle, Foitzik, Richard, Bozikis, Ylva, Helmey, Catherine

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Derivados de benzotiofeno, tienopiridina e tienopirimidina para modulação de sting von PAUL ANTHONY STUPPLE, BENJAMIN JOSEPH MORROW, ANTHONY NICHOLAS CUZZUPE, JONATHAN GRANT HUBERT, MICHELLE ANG CAMERINO, YLVA ELISABET BERGMAN BOZIKIS

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COMPUESTOS von FOITZIK, Richard, HEMLEY, Catherine, STUPPLE, Paul, MORROW, Benjamin, CAMERINO, Michelle, WALKER, Scott, LAGIAKOS, Helen, BOZIKIS, Ylva

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DERIVADOS DE BENZISOXAZOL SULFONAMIDA von CAMERINO, Michelle Ang, KUMPF, Robert Arnold, SUTTON, Scott Channing, STUPPLE, Paul Anthony, BRODSKY, Oleg, KUNG, Pei-Pei, GREASLEY, Samantha Elizabeth, HOFFMAN, Robert Louis, RICHARDSON, Paul Francis, BOZIKIS, Ylva Elisabet Bergman

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Compuestos von CAMERINO, Michelle Ang, STUPPLE, Paul Anthony, LAGIAKOS, Helen Rachel, HEMLEY, Catherine Fae, FOITZIK, Richard Charles, MORROW, Benjamin Joseph, WALKER, Scott Raymond, BOZIKIS, Ylva Elisabet Bergman

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COMPOUNDS von MORROW Benjamin Joseph, CAMERINO Michelle Ang, WALKER Scott Raymond, STUPPLE Paul Anthony, FOITZIK Richard Charles, LAGIAKOS Helen Rachel, HEMLEY Catherine Fae, BOZIKIS Ylva Elisabet Bergman

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BENZISOXAZOLE SULFONAMIDE DERIVATIVES von KUMPF Robert Arnold, SUTTON Scott Channing, CAMERINO Michelle Ang, KUNG Pei-pei, BRODSKY Oleg, STUPPLE Paul Anthony, HOFFMAN Robert Louis, RICHARDSON Paul Francis, BOZIKIS Ylva Elisabet Bergman, GREASLEY Samantha Elizabeth

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Derivados de sulfonamida de benzisoxazol von ROBERT ARNOLD KUMPF, PAUL ANTHONY STUPPLE, SAMANTHA ELIZABETH GREASLEY, BRODSKY OLEG, PAUL FRANCIS RICHARDSON, KUNG PEI-PEI, SCOTT CHANNING SUTTON, ROBERT LOUIS HOFFMAN, MICHELLE ANG CAMERINO, YLVA ELISABET BERGMAN BOZIKIS

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COMPUESTOS von PAUL ANTHONY STUPPLE, BENJAMIN JOSEPH MORROW, RICHARD CHARLES FOITZIK, CATHERINE FAE HEMLEY, HELEN RACHEL LAGIAKOS, MICHELLE ANG CAMERINO, YLVA ELISABET BERGMAN BOZIKIS, SCOTT RAYMOND WALKER

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compostos von PAUL ANTHONY STUPPLE, BENJAMIN JOSEPH MORROW, RICHARD CHARLES FOITZIK, CATHERINE FAE HEMLEY, HELEN RACHEL LAGIAKOS, MICHELLE ANG CAMERINO, YLVA ELISABET BERGMAN BOZIKIS, SCOTT RAYMOND WALKER

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Compuestos von CAMERINO, Michelle Ang, STUPPLE, Paul Anthony, LAGIAKOS, Helen Rachel, HEMLEY, Catherine Fae, FOITZIK, Richard Charles, MORROW, Benjamin Joseph, WALKER, Scott Raymond, BOZIKIS, Ylva Elisabet Bergman

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BENZISOXAZOLE SULFONAMIDE DERIVATIVES von CAMERINO, Michelle Ang, KUMPF, Robert Arnold, SUTTON, Scott Channing, BOZIKIS, Ylva, Elisabet, Bergman, STUPPLE, Paul Anthony, BRODSKY, Oleg, KUNG, Pei-Pei, RICHARDSON, Paul Francis, GREASLEY, Samantha Elizabeth, HOFFMAN, Robert Louis

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