Identification of Novel Cannabinoid CB1 Receptor Antagonists by Using Virtual Screening with a Pharmacophore Model von Wang, Hongwu, Duffy, Ruth A, Boykow, George C, Chackalamannil, Samuel, Madison, Vincent S

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Discovery of Potent Orally Active Thrombin Receptor (Protease Activated Receptor 1) Antagonists as Novel Antithrombotic Agents von Chackalamannil, Samuel, Xia, Yan, Greenlee, William J, Clasby, Martin, Doller, Darìo, Tsai, Hsingan, Asberom, Theodros, Czarniecki, Michael, Ahn, Ho-Sam, Boykow, George, Foster, Carolyn, Agans-Fantuzzi, Jacqueline, Bryant, Matthew, Lau, Janice, Chintala, Madhu

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Inhibition of cellular action of thrombin by N3-cyclopropyl-7-{[4-(1-methylethyl)phenyl]methyl}-7H-pyrrolo[3,2-f]quinazoline- 1,3-diamine (SCH 79797), a nonpeptide thrombin recepto... von AHN, Ho-Sam, FOSTER, Carolyn, BOYKOW, George, STAMFORD, Andrew, MANNA, Mahua, GRAZIANO, Michael

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Metabolism-Based Identification of a Potent Thrombin Receptor Antagonist von Clasby, Martin C, Chackalamannil, Samuel, Czarniecki, Michael, Doller, Dario, Eagen, Keith, Greenlee, William, Kao, Grace, Lin, Yan, Tsai, Hsingan, Xia, Yan, Ahn, Ho-Sam, Agans-Fantuzzi, Jacqueline, Boykow, George, Chintala, Madhu, Foster, Carolyn, Smith-Torhan, April, Alton, Kevin, Bryant, Matthew, Hsieh, Yunsheng, Lau, Janice, Palamanda, Jairam

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Diaryl piperidines as CB1 receptor antagonists von SCOTT, Jack D, LI, Sarah W, STAMFORD, Andrew W, CHACKALAMANNIL, Samuel, LACHOWICZ, Jean E, GREENLEE, William J, HONGWU WANG, YAN XIA, JAYNE, Charles L, MILLER, Michael W, DUFFY, Ruth A, BOYKOW, George C, KOWALSKI, Timothy J, SPAR, Brian D

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Discovery of a Novel, Orally Active Himbacine-Based Thrombin Receptor Antagonist (SCH 530348) with Potent Antiplatelet Activity von Chackalamannil, Samuel, Wang, Yuguang, Greenlee, William J, Hu, Zhiyong, Xia, Yan, Ahn, Ho-Sam, Boykow, George, Hsieh, Yunsheng, Palamanda, Jairam, Agans-Fantuzzi, Jacqueline, Kurowski, Stan, Graziano, Michael, Chintala, Madhu

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Himbacine derived thrombin receptor antagonists: Discovery of a new tricyclic core von Clasby, Martin C., Chackalamannil, Samuel, Czarniecki, Michael, Doller, Darío, Eagen, Keith, Greenlee, William J., Lin, Yan, Tagat, Jayaram R., Tsai, Hsingan, Xia, Yan, Ahn, Ho-Sam, Agans-Fantuzzi, Jacqueline, Boykow, George, Chintala, Madhu, Hsieh, Yunsheng, McPhail, Andrew T.

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Himbacine derived thrombin receptor (PAR-1) antagonists: SAR of the pyridine ring von Xia, Yan, Chackalamannil, Samuel, Clasby, Martin, Doller, Darío, Eagen, Keith, Greenlee, William J., Tsai, Hsingan, Agans-Fantuzzi, Jacqueline, Ahn, Ho-Sam, Boykow, George C., Hsieh, Yunsheng, Lunn, Charles A., Chintala, Madhu

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Himbacine derived thrombin receptor (PAR-1) antagonists: Structure–activity relationship of the lactone ring von Xia, Yan, Chackalamannil, Samuel, Chan, Tze-Ming, Czarniecki, Michael, Doller, Darío, Eagen, Keith, Greenlee, William J., Tsai, Hsingan, Wang, Yuguang, Ahn, Ho-Sam, Boykow, George C., McPhail, Andrew T.

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Binding of a Thrombin Receptor Tethered Ligand Analogue to Human Platelet Thrombin Receptor von Ahn, H S, Foster, C, Boykow, G, Arik, L, Smith-Torhan, A, Hesk, D, Chatterjee, M

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Hypocholesterolemic activity of a novel inhibitor of cholesterol absorption, SCH 48461 von Salisbury, Brian G, Davis, Harry R, Burrier, Robert E, Burnett, Duane A, Boykow, George, Caplen, Mary Ann, Clemmons, Anthony L, Compton, Douglas S, Hoos, Lizbeth M, McGregor, Daniel G, Schnitzer-Polokoff, Robin, Smith, April A, Weig, Blair C, Zilli, Deborah L, Clader, John W, Sybertz, Edmund J

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Effects of the selective adenosine A2A receptor antagonist, SCH 412348, on the parkinsonian phenotype of MitoPark mice von Smith, Karen M., Browne, Susan E., Jayaraman, Srinivasan, Bleickardt, Carina J., Hodge, Lisa M., Lis, Edward, Yao, Leon, Rittle, Sunday L., Innocent, Nathalie, Mullins, Deborra E., Boykow, George, Reynolds, Ian J., Hill, David, Parker, Eric M., Hodgson, Robert A.

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Himbacine-Derived Thrombin Receptor Antagonists: C 7 -Spirocyclic Analogues of Vorapaxar von Chelliah, Mariappan V., Eagen, Keith, Guo, Zhuyan, Chackalamannil, Samuel, Xia, Yan, Tsai, Hsingan, Greenlee, William J., Ahn, Ho-Sam, Kurowski, Stan, Boykow, George, Hsieh, Yunsheng, Chintala, Madhu

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Iminopyrimidinones: A novel pharmacophore for the development of orally active renin inhibitors von McKittrick, Brian A., Caldwell, John P., Bara, Thomas, Boykow, George, Chintala, Madhu, Clader, John, Czarniecki, Michael, Courneya, Brandy, Duffy, Ruth, Fleming, Linda, Giessert, Rachel, Greenlee, William J., Heap, Charles, Hong, Liwu, Huang, Ying, Iserloh, Ulrich, Josien, Hubert, Khan, Tanweer, Korfmacher, Walter, Liang, Xian, Mazzola, Robert, Mitra, Soumya, Moore, Kristina, Orth, Peter, Rajagopalan, Murali, Roy, Sudipta, Sakwa, Samuel, Strickland, Corey, Vaccaro, Henry, Voigt, Johannes, Wang, Hongwu, Wong, Jesse, Zhang, Rumin, Zych, Andrew

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Effects of the selective adenosine A sub(2A) receptor antagonist, SCH 412348, on the parkinsonian phenotype of MitoPark mice von Smith, Karen M, Browne, Susan E, Jayaraman, Srinivasan, Bleickardt, Carina J, Hodge, Lisa M, Lis, Edward, Yao, Leon, Rittle, Sunday L, Innocent, Nathalie, Mullins, Deborra E, Boykow, George, Reynolds, Ian J, Hill, David, Parker, Eric M, Hodgson, Robert A

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Himbacine-Derived Thrombin Receptor Antagonists: C7‑Spirocyclic Analogues of Vorapaxar von Chelliah, Mariappan V, Eagen, Keith, Guo, Zhuyan, Chackalamannil, Samuel, Xia, Yan, Tsai, Hsingan, Greenlee, William J, Ahn, Ho-Sam, Kurowski, Stan, Boykow, George, Hsieh, Yunsheng, Chintala, Madhu

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Label-Free, LC-MS-Based Assays to Quantitate Small-Molecule Antagonist Binding to the Mammalian BLT1 Receptor von Chen, Xun, Stout, Steven, Mueller, Uwe, Boykow, George, Visconti, Richard, Siliphaivanh, Phieng, Spencer, Kerrie, Presland, Jeremy, Kavana, Michael, Basso, Andrea D., McLaren, David G., Myers, Robert W.

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Discovery of a vorapaxar analog with increased aqueous solubility von Xia, Yan, Chackalamannil, Samuel, Greenlee, William J., Wang, Yuguang, Hu, Zhiyong, Root, Yuriko, Wong, Jesse, Kong, Jianshe, Ahn, Ho-Sam, Boykow, George, Hsieh, Yunsheng, Kurowski, Stan, Chintala, Madhu

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Discovery of nor-seco himbacine analogs as thrombin receptor antagonists von Chelliah, Mariappan V., Chackalamannil, Samuel, Xia, Yan, Eagen, Keith, Greenlee, William J., Ahn, Ho-Sam, Agans-Fantuzzi, Jacqueline, Boykow, George, Hsieh, Yunsheng, Bryant, Matthew, Chan, Tze-Ming, Chintala, Madhu

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Heterotricyclic Himbacine Analogs as Potent, Orally Active Thrombin Receptor (Protease Activated Receptor-1) Antagonists von Chelliah, Mariappan V, Chackalamannil, Samuel, Xia, Yan, Eagen, Keith, Clasby, Martin C, Gao, Xiaobang, Greenlee, William, Ahn, Ho-Sam, Agans-Fantuzzi, Jacqueline, Boykow, George, Hsieh, Yunsheng, Bryant, Matthew, Palamanda, Jairam, Chan, Tze-Ming, Hesk, David, Chintala, Madhu

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