THU0275 IL-6 Receptor (IL-6R) Blockade with Sarilumab Reduced Circulating Markers Related to Synovial Inflammation and Structural Damage in Patients with Rheumatoid Arthritis (RA)... von Fiore, S., Boyapati, A., Hamon, S.C., van Adelsberg, J., Liu, M., Hamilton, J.D.

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Systemic Inflammation in Preclinical Ulcerative Colitis von Bergemalm, Daniel, Andersson, Erik, Hultdin, Johan, Eriksson, Carl, Rush, Stephen T., Kalla, Rahul, Adams, Alex T., Keita, Åsa V., D’Amato, Mauro, Gomollon, Fernando, Jahnsen, Jørgen, Arnott, Ian D., Bayes, Monica, Bonfiglio, Ferdinando, Boyapati, Ray K., Carstens, Adam, Casén, Christina, Ciemniejewska, Ewa, Dahl, Fredrik A., Detlie, Trond Espen, Drummond, Hazel E., Ekeland, Gunn S., Ekman, Daniel, Frengen, Anna B., Gullberg, Mats, Gut, Ivo G., Gut, Marta, Heath, Simon C., Hjelm, Fredrik, Hjortswang, Henrik, Ho, Gwo-Tzer, Jonkers, Daisy, Söderholm, Johan, Kennedy, Nicholas A., Lees, Charles W., Lindahl, Torbjørn, Lindqvist, Mårten, Merkel, Angelika, Modig, Eddie, Moen, Aina E.F., Nilsen, Hilde, Nimmo, Elaine R., Noble, Colin L., Nordberg, Niklas, O’Leary, Kate R., Ocklind, Anette, Olbjørn, Christine, Pettersson, Erik, Pierik, Marieke, Dominique, Ricanek, Petr, Satsangi, Jack, Repsilber, Dirk, Karling, Pontus, Halfvarson, Jonas

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Decompressive Craniectomy versus Craniotomy for Acute Subdural Hematoma von Hutchinson, Peter J., Adams, Hadie, Mohan, Midhun, Devi, Bhagavatula I., Uff, Christopher, Hasan, Shumaila, Mee, Harry, Wilson, Mark H., Gupta, Deepak K., Bulters, Diederik, Zolnourian, Ardalan, McMahon, Catherine J., Stovell, Matthew G., Al-Tamimi, Yahia Z., Tewari, Manoj K., Tripathi, Manjul, Thomson, Simon, Viaroli, Edoardo, Belli, Antonio, King, Andrew T., Helmy, Adel E., Timofeev, Ivan S., Pyne, Sarah, Shukla, Dhaval P., Bhat, Dhananjaya I., Maas, Andrew R., Servadei, Franco, Manley, Geoffrey T., Barton, Garry, Turner, Carole, Menon, David K., Gregson, Barbara, Kolias, Angelos G.

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Glycosylation of Immunoglobulin G Associates With Clinical Features of Inflammatory Bowel Diseases von Šimurina, Mirna, de Haan, Noortje, Vučković, Frano, Kennedy, Nicholas A., Štambuk, Jerko, Falck, David, Trbojević-Akmačić, Irena, Clerc, Florent, Razdorov, Genadij, Khon, Anna, Latiano, Anna, D'Incà, Renata, Danese, Silvio, Targan, Stephan, Landers, Carol, Dubinsky, Marla, Campbell, Harry, Zoldoš, Vlatka, Permberton, Iain K., Kolarich, Daniel, Fernandes, Daryl L., Theorodorou, Evropi, Merrick, Victoria, Spencer, Daniel I., Gardner, Richard A., Doran, Ray, Shubhakar, Archana, Boyapati, Ray, Rudan, Igor, Lionetti, Paolo, Krištić, Jasminka, Novokmet, Mislav, Pučić-Baković, Maja, Gornik, Olga, Andriulli, Angelo, Cantoro, Laura, Sturniolo, Giancarlo, Fiorino, Gionata, Manetti, Natalia, Arnott, Ian D., Noble, Colin L., Lees, Charlie W., Shand, Alan G., Ho, Gwo-Tzer, Dunlop, Malcolm G., Murphy, Lee, Gibson, Jude, Evenden, Louise, Wrobel, Nicola, Gilchrist, Tamara, Fawkes, Angie, Kammeijer, Guinevere S.M., Vojta, Aleksandar, Samaržija, Ivana, Markulin, Dora, Klasić, Marija, Dobrinić, Paula, Aulchenko, Yurii, van den Heuve, Tim, Jonkers, Daisy, Pierik, Marieke, McGovern, Dermot P.B., Annese, Vito, Wuhrer, Manfred, Lauc, Gordan

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Plasma N-Glycan Signatures Are Associated With Features of Inflammatory Bowel Diseases von Clerc, Florent, Novokmet, Mislav, Dotz, Viktoria, Reiding, Karli R., de Haan, Noortje, Kammeijer, Guinevere S.M., Dalebout, Hans, Bladergroen, Marco R., Vukovic, Frano, Rapp, Erdmann, Satsangi, Jack, Nimmo, Elaine R., Ventham, Nicholas T., Drummond, Hazel, Kalla, Rahul, Adams, Alex T., O'Leary, Kate, Boyapati, Ray, Wilson, David C., Merrick, Victoria, Campbell, Harry, Theodoratou, Evropi, Rudan, Igor, Kennedy, Nicholas A., Fernandes, Daryl L., Spencer, Daniel I.R., Gardner, Richard A., Shubhakar, Archana, Urbanowicz, Paulina A., Trbojević-Akmačić, Irena, Krištić, Jasminka, Štambuk, Jerko, Pučić-Baković, Maja, Vilaj, Marija, Pezer, Marija, Razdorov, Genadij, Šimurina, Mirna, Gornik, Olga, Biscaglia, Giuseppe, Palmieri, Orazio, Bossa, Fabrizio, D'incà, Renata, Danese, Silvio, Kohn, Anna, Pemberton, Iain K., Kolarich, Daniel, Zoldos, Vlatka, Aulchenko, Yurii, Pierik, Marieke, Jonkers, Daisy, van den Heuvel, Tim, Targan, Stephan R., Barron, Gildardo, Manetti, Natalia, Latiano, Anna, McGovern, Dermot P.B., Annese, Vito, Lauc, Gordan, Wuhrer, Manfred

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Naltrexone differentially modulates the neural correlates of motor impulse control in abstinent alcohol‐dependent and polysubstance‐dependent individuals von Nestor, Liam J., Paterson, Louise M., Murphy, Anna, McGonigle, John, Orban, Csaba, Reed, Laurence, Taylor, Eleanor, Flechais, Remy, Smith, Dana, Bullmore, Edward T., Ersche, Karen D., Suckling, John, Elliott, Rebecca, Deakin, Bill, Rabiner, Ilan, Lingford Hughes, Anne, Sahakian, Barbara J., Robbins, Trevor W., Nutt, David J., Passetti, Filippo, Faravelli, Luca, Erritzoe, David, Mick, Inge, Kalk, Nicola, Waldman, Adam, Kuchibatla, Shankar, Boyapati, Venkataramana, Metastasio, Antonio, Faluyi, Yetunde, Fernandez‐Egea, Emilio, Abbott, Sanja, Voon, Valerie

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Characterisation of the Circulating Transcriptomic Landscape in Inflammatory Bowel Disease Provides Evidence for Dysregulation of Multiple Transcription Factors Including NFE2, SPI... von Nowak, Jan K, Adams, Alex T, Kalla, Rahul, Lindstrøm, Jonas C, Vatn, Simen, Bergemalm, Daniel, Keita, Åsa V, Gomollón, Fernando, Jahnsen, Jørgen, Vatn, Morten H, Ricanek, Petr, Ostrowski, Jerzy, Walkowiak, Jaroslaw, Halfvarson, Jonas, Satsangi, Jack

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COVID-19 impact on Surgical Training and Recovery Planning (COVID-STAR) - A cross-sectional observational study von Clements, Joshua Michael, Burke, Josh, Nally, Deirdre, Rabie, Mohamed, Kane, Elizabeth, Barlow, Emma, Mohamed, Walid, King, Martin, McClymont, Liusaidh, George, Manish, Tolofari, Sotonye, McKay, Siobhan, Jayasekera, Ashan, Steele, Duncan, Badran, Abdul, Summers, Dominic, Harji, Deena, Weston-Petrides, Gina, Nasher, Omar, Baker, Benjamin, Patel, Shaneel, Boyapati, Raghuram, Peckham-Cooper, Adam, Bashyam, Anthony, Stovell, Matthew, Zhang, Catherine, Thomas, Rachel, Sarmah, Panchali, Wilkins, Alexander, Dua, Radhika, Gokani, Vimal, Dovell, George, Rintoul-Hoad, Sophie

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Analysis of Systemic Epigenetic Alterations in Inflammatory Bowel Disease: Defining Geographical, Genetic and Immune-Inflammatory influences on the Circulating Methylome von Kalla, Rahul, Adams, Alex T, Nowak, Jan K, Bergemalm, Daniel, Vatn, Simen, Ventham, Nicholas T, Kennedy, Nicholas A, Ricanek, Petr, Lindstrom, Jonas, Söderholm, Johan, Pierik, Marie, D'Amato, Mauro, Gomollón, Fernando, Olbjørn, Christine, Richmond, Rebecca, Relton, Caroline, Jahnsen, Jørgen, Vatn, Morten H, Halfvarson, Jonas, Satsangi, Jack

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Cost-effectiveness of craniotomy versus decompressive craniectomy for UK patients with traumatic acute subdural haematoma von Barton, Garry, Kolias, Angelos G, Turner, Carole, Mohan, Midhun, Uff, Christopher, Wilson, Mark, Zolnourian, Ardalan, Al-Tamimi, Yahia, Menon, David, Mee, Harry, Kolias, Angelos G, Mohan, Midhun, Helmy, Adel E, Hutchinson, Peter J, Kirkpatrick, Peter J, Owen, Nicola, Grieve, Kirsty, Tarantino, Silvia, Corteen, Liz, Corn, Janet, Jalloh, Ibrahim, Walker, Kamila, Venturini, Sara, Tülü, Selma, Chitsenega, Chipo, Bhatti, Muhammad, Zaben, Malik, Liudmila, Joseph Merola, Glanz, Laurence, Kumaria, Ashwin, Belli, Antonio, Ventura, Maximina, Georges, Husam, Eglinton, Charlotte, Sunderland, Geraint, Kitchen, John, Zakaria, Rushid, Thomson, Simon, Makawa, Linetty, Kambafwile, Mary, Papadopoulos, Marios C, Joseph, Mathew, Trippier, Sarah, Marcus, Hani, Thomas, Rhys, Young, Louise, D’Mello, Andrea, Bulters, Diederik, Zolnourian, Ardalan, Visentin, Elisa, Johnston, Paul, Arzoglou, Vasileios, Tolias, Christos, Clegg, Rose, Cole, Grace, Holliman, Damian, Hare, Marianne, Nelson, Richard, Joshi, Shabin, Ward, Geraldine, Fleming, Emma, Bhagavatula, Indira Devi, Bhat, Dhananjaya Ishwar, Shukla, Dhaval Prem, Konar, Kanti, Shanhag, Nagesh, Valluri, Vaishali Nl, Tewari, Manoj Kumar, Bindra, Ashish, Keong, Nicole, Wei, Chen Min, Kwok, Janell, King, Kam, Stippler, Martina, Nelton, Emmalin, Whitworth, Louis Anthony, Stutzman, Sonja, Moore, Tracey, Chang, Jason J, Moses, George B, Lewis, Erin, Stone, Melvin, Costa, Leodante Da, Alkherayf, Fahad, Moldovan, Ioana, Fountas, Kostas, Paschalis, Thanasis, Luisa, Maria, Lenzsér, Gábor, Narayanan, Vairavan, Jayapalan, Ronie Romelean, Gregson, Barbara, Nagarajan, Sridevi, Turner, David, Piercy, James, Cowie, Christopher, Jillings, Michele, Shaw, Simon, Grieve, Joan, Cook, Jonathan

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Promoter methylation of the MGAT3 and BACH2 genes correlates with the composition of the immunoglobulin G glycome in inflammatory bowel disease von Klasić, Marija, Markulin, Dora, Vojta, Aleksandar, Samaržija, Ivana, Biruš, Ivan, Dobrinić, Paula, Ventham, Nicholas T, Trbojević-Akmačić, Irena, Šimurina, Mirna, Štambuk, Jerko, Razdorov, Genadij, Kennedy, Nicholas A, Satsangi, Jack, Dias, Ana M, Pinho, Salome, Annese, Vito, Latiano, Anna, D'Inca, Renata, Lauc, Gordan, Zoldoš, Vlatka

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The Imperial College Cambridge Manchester (ICCAM) platform study: An experimental medicine platform for evaluating new drugs for relapse prevention in addiction. Part A: Study desc... von Paterson, Louise M, Flechais, Remy SA, Murphy, Anna, Reed, Laurence J, Abbott, Sanja, Boyapati, Venkataramana, Elliott, Rebecca, Erritzoe, David, Ersche, Karen D, Faluyi, Yetunde, Faravelli, Luca, Fernandez-Egea, Emilio, Kalk, Nicola J, Kuchibatla, Shankar S, McGonigle, John, Metastasio, Antonio, Mick, Inge, Nestor, Liam, Orban, Csaba, Passetti, Filippo, Rabiner, Eugenii A, Smith, Dana G, Suckling, John, Tait, Roger, Taylor, Eleanor M, Waldman, Adam D, Robbins, Trevor W, Deakin, JF William, Nutt, David J, Lingford-Hughes, Anne R

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The prevalence and transcriptional activity of the mucosal microbiota of ulcerative colitis patients von Moen, Aina E. Fossum, Lindstrøm, Jonas Christoffer, Tannæs, Tone Møller, Vatn, Simen, Ricanek, Petr, Vatn, Morten H., Jahnsen, Jørgen

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P1.22-07 Predictive Biomarkers of Response to REGN5093 to Guide Patient Selection in MET-Altered Advanced Non-small Cell Lung Cancer von Navas, T., Drilon, A.E., Cho, B.C., Viau, J., Tao, W., Zhu, Y.O., Giangreco, N., Perez, J., Masinde, S., Paccaly, A., Krishna, R., Li, Y., Li, S., Daly, C., Patel, S., Laughlin, M., Seebach, F., Pouliot, J.F., Rietschel, P., Magnan, H., Boyapati, A.

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Genome-Wide Methylation Profiling in 229 Patients With Crohn’s Disease Requiring Intestinal Resection: Epigenetic Analysis of the Trial of Prevention of Post-operative Crohn’s Dise... von Ventham, Nicholas T., Kennedy, Nicholas A., Kalla, Rahul, Adams, Alex T., Noble, Alexandra, Ennis, Holly, Arnott, Ian, Cahill, Aiden, Smith, Malcolm, Ahmad, Tariq, Subramanian, Sreedhar, Travis, Simon, Morris, John, Hamlin, John, Dhar, Anjan, Nwokolo, Chuka, Creed, Tom, Bloom, Stuart, Yousif, Mohamed, Thomas, Linzi, Campbell, Simon, Lewis, Stephen J., Sebastian, Shaji, Sen, Sandip, Lal, Simon, Hawkey, Chris, Murray, Charles, Cummings, Fraser, Goh, Jason, Lindsay, James O., Arebi, Naila, Potts, Lindsay, McKinley, Aileen J., Thomson, John M., Todd, John A., Collie, Mhairi, Mowat, Ashley, Gaya, Daniel R., Winter, Jack, Naismith, Graham D., Keerie, Catriona, Lewis, Steff, Prescott, Robin J., Campbell, Harry, McGovern, Dermot P.B., Annese, Vito, Zoldoš, Vlatka, Permberton, Iain K., Wuhrer, Manfred, Kolarich, Daniel, Fernandes, Daryl L., Theorodorou, Evropi, Daniel I. Spencer, Victoria Merrick, Gardner, Richard A., Doran, Ray, Shubhakar, Archana, Boyapati, Ray, Rudan, Igor, Lionetti, Paolo, Akmačić, Irena Trbojević, Krištić, Jasminka, Vuč ković, Frano, Štambuk, Jerko, Novokmet, Mislav, Pučić-Baković, Maja, Gornik, Olga, Andriulli, Angelo, Cantoro, Laura, Sturniolo, Giancarlo, Fiorino, Gionata, Manetti, Natalia, Latiano, Anna, Kohn, Anna, D’Inca`, Renata, Danese, Silvio, Arnott, Ian D., Noble, Colin L., Lees, Charlie W., Shand, Alan G., Murphy, Lee, Gibson, Jude, Evenden, Louise, Wrobel, Nicola, Gilchrist, Tamara, Fawkes, Angie, Kammeijer, Guinevere S.M., Clerc, Florent, de Haan, Noortje, Vojta, Aleksandar, Samaržija, Ivana, Markulin, Dora, Klasić, Marija, Dobrinić, Paula, Aulchenko, Yurii, van den Heuve, Tim, Jonkers, Daisy, Pierik, Marieke, Mowat, Craig, Dunlop, Malcolm G., Satsangi, Jack

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Critical Role for SV40 Small-t Antigen in Human Cell Transformation von Yu, Jing, Boyapati, Anita, Rundell, Kathleen

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Deletion of an AML1-ETO C-Terminal NcoR/SMRT-Interacting Region Strongly Induces Leukemia Development von Yan, Ming, Burel, Sebastien A., Peterson, Luke F., Kanbe, Eiki, Iwasaki, Hiromi, Boyapati, Anita, Hines, Robert, Akashi, Koichi, Zhang, Dong-Er, Vogt, Peter K.

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S189: EARLY, DEEP, AND DURABLE RESPONSES, AND LOW RATES OF CRS WITH REGN5458, A BCMAXCD3 BISPECIFIC ANTIBODY, IN A PHASE 1/2 FIRST‐IN‐HUMAN STUDY IN PATIENTS WITH RELAPSED/REFRACTO... von Zonder, J. A., Richter, J., Bumma, N., Brayer, J., Hoffman, J. E., Bensinger, W. I., Wu, K. L., Xu, L., Chokshi, D., Boyapati, A., Cronier, D., Houvras, Y., Rodriguez Lorenc, K., Kroog, G. S., Dhodapkar, M. V., Lentzsch, S., Cooper, D., Jagannath, S.

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The Hematopoietic Transcription Factor AML1 (RUNX1) Is Negatively Regulated by the Cell Cycle Protein Cyclin D3 von Peterson, Luke F, Boyapati, Anita, Ranganathan, Velvizhi, Iwama, Atsushi, Tenen, Daniel G, Tsai, Schickwann, Zhang, Dong-Er

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An Unusual Presentation of Herpes Simplex Virus Encephalitis von Geluk, Michael, Papadopoulos, George, Olver, James, Johnson, Paul D. R., Boyapati, Ray

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