Tissue-engineered intervertebral discs produce new matrix, maintain disc height, and restore biomechanical function to the rodent spine von Bowles, Robby D, Gebhard, Harry H, Härtl, Roger, Bonassar, Lawrence J

Volltext

Multiplex epigenome editing of ion channel expression in nociceptive neurons abolished degenerative IVD‐conditioned media‐induced mechanical sensitivity von Stover, Joshua D., Trone, Matthew A., Lawrence, Brandon, Bowles, Robby D.

Volltext

Lentiviral CRISPR Epigenome Editing of Inflammatory Receptors as a Gene Therapy Strategy for Disc Degeneration von Farhang, Niloofar, Ginley-Hidinger, Matt, Berrett, Kristofer C, Gertz, Jason, Lawrence, Brandon, Bowles, Robby D

Volltext

Improving Cell Therapy Survival and Anabolism in Harsh Musculoskeletal Disease Environments von Farhang, Niloofar, Silverman, Lara, Bowles, Robby D.

Volltext

Degenerative IVD conditioned media and acidic pH sensitize sensory neurons to cyclic tensile strain von Stover, Joshua D., Lawrence, Brandon, Bowles, Robby D.

Volltext

Targeted CRISPR regulation of ZNF865 enhances stem cell cartilage deposition, tissue maturation rates, and mechanical properties in engineered intervertebral discs von Levis, Hunter, Lewis, Christian, Fainor, Matthew, Lawal, Ameerah, Stockham, Elise, Weston, Jacob, Farhang, Niloofar, Gullbrand, Sarah E., Bowles, Robby D.

Volltext

Synergistic CRISPRa-Regulated Chondrogenic Extracellular Matrix Deposition Without Exogenous Growth Factors von Farhang, Niloofar, Davis, Bryton, Weston, Jacob, Ginley-Hidinger, Matthew, Gertz, Jason, Bowles, Robby D.

Volltext

Multiplex Epigenome Editing of Dorsal Root Ganglion Neuron Receptors Abolishes Redundant Interleukin 6, Tumor Necrosis Factor Alpha, and Interleukin 1β Signaling by the Degenerativ... von Stover, Joshua D, Farhang, Niloofar, Lawrence, Brandon, Bowles, Robby D

Volltext

CRISPR Epigenome Editing of AKAP150 in DRG Neurons Abolishes Degenerative IVD-Induced Neuronal Activation von Stover, Joshua D., Farhang, Niloofar, Berrett, Kristofer C., Gertz, Jason, Lawrence, Brandon, Bowles, Robby D.

Volltext

Therapeutic CRISPR epigenome editing of inflammatory receptors in the intervertebral disc von Stover, Joshua D., Trone, Matthew A.R., Weston, Jacob, Lewis, Christian, Levis, Hunter, Farhang, Niloofar, Philippi, Matthew, Zeidan, Michelle, Lawrence, Brandon, Bowles, Robby D.

Volltext

Multiplex gene editing to promote cell survival using low-pH clustered regularly interspaced short palindromic repeats activation (CRISPRa) gene perturbation von Levis, Hunter, Weston, Jacob, Austin, Brooke, Larsen, Bryce, Ginley-Hidinger, Matthew, Gullbrand, Sarah E., Lawrence, Brandon, Bowles, Robby D.

Volltext

CRISPR-Based Epigenome Editing of Cytokine Receptors for the Promotion of Cell Survival and Tissue Deposition in Inflammatory Environments von Farhang, Niloofar, Brunger, Jonathan M., Stover, Joshua D., Thakore, Pratiksha I., Lawrence, Brandon, Guilak, Farshid, Gersbach, Charles A., Setton, Lori A., Bowles, Robby D.

Volltext

Synthesis and characterization of silk fibroin microparticles for intra-articular drug delivery von Mwangi, Timothy K., Bowles, Robby D., Tainter, David M., Bell, Richard D., Kaplan, David L., Setton, Lori A.

Volltext

Injectable laminin-functionalized hydrogel for nucleus pulposus regeneration von Francisco, Aubrey T, Mancino, Robert J, Bowles, Robby D, Brunger, Jonathan M, Tainter, David M, Chen, Yi-Te, Richardson, William J, Guilak, Farshid, Setton, Lori A

Volltext

Self-Assembly of Aligned Tissue-Engineered Annulus Fibrosus and Intervertebral Disc Composite Via Collagen Gel Contraction von Bowles, Robby D., Williams, Rebecca M., Zipfel, Warren R., Bonassar, Lawrence J.

Volltext

Microfluidic Flow Cell Array for Controlled Cell Deposition in Engineered Musculoskeletal Tissues von Ede, David, Davidoff, Nikki, Blitch, Alejandro, Farhang, Niloofar, Bowles, Robby D.

Volltext

In Vivo Luminescence Imaging of NF‐κB Activity and Serum Cytokine Levels Predict Pain Sensitivities in a Rodent Model of Osteoarthritis von Bowles, Robby D., Mata, Brian A., Bell, Richard D., Mwangi, Timothy K., Huebner, Janet L., Kraus, Virginia B., Setton, Lori A.

Volltext

Image-based tissue engineering of a total intervertebral disc implant for restoration of function to the rat lumbar spine von Bowles, Robby D., Gebhard, Harry H., Dyke, Jonathan P., Ballon, Douglas J., Tomasino, Andre, Cunningham, Matthew E., Härtl, Roger, Bonassar, Lawrence J.

Volltext

Novel Model-Based Inquiry of Ionic Bonding in Alginate Hydrogels Used in Tissue Engineering for High School Students von Bowles, Robby D, Saroka, James M, Archer, Shivaun D, Bonassar, Lawrence J

Volltext

Multiplex Gene Editing to Promote Cell Survival using Low-pH CRISPRa Gene Perturbation von Levis, Hunter, Weston, Jacob, Austin, Brooke, Larsen, Bryce, Ginley-Hidinger, Matthew, Gullbrand, Sarah E., Lawrence, Brandon, Bowles, Robby D.

Volltext