Plasma Proteomic Markers of Iron and Risk of Diabetes in a Cohort of African American and White American Current and Former Smokers von Conway, Rebecca Baqiyyah, Pratte, Katherine A, Bowler, Russell Paul, Young, Kendra A, Kinney, Gregory L, Austin, Erin, Li, Yisha, McClain, Donald, Hokanson, John, Crapo, James D

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GOLD 2011 disease severity classification in COPDGene: a prospective cohort study von Han, MeiLan K, Dr, Muellerova, Hana, PhD, Curran-Everett, Douglas, Prof, Dransfield, Mark T, MD, Washko, George R, MD, Regan, Elizabeth A, MD, Bowler, Russell P, MD, Beaty, Terri H, Prof, Hokanson, John E, Prof, Lynch, David A, Prof, Jones, Paul W, Prof, Anzueto, Antonio, Prof, Martinez, Fernando J, Prof, Crapo, James D, Prof, Silverman, Edwin K, MD, Make, Barry J, Prof

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Comparison of Proteomic Assessment Methods in Multiple Cohort Studies von Raffield, Laura M., Dang, Hong, Pratte, Katherine A., Jacobson, Sean, Gillenwater, Lucas A., Ampleford, Elizabeth, Barjaktarevic, Igor, Basta, Patricia, Clish, Clary B., Comellas, Alejandro P., Cornell, Elaine, Curtis, Jeffrey L., Doerschuk, Claire, Durda, Peter, Emson, Claire, Freeman, Christine M., Guo, Xiuqing, Hastie, Annette T., Hawkins, Gregory A., Herrera, Julio, Johnson, W. Craig, Labaki, Wassim W., Liu, Yongmei, Masters, Brett, Miller, Michael, Ortega, Victor E., Papanicolaou, George, Peters, Stephen, Taylor, Kent D., Rich, Stephen S., Rotter, Jerome I., Auer, Paul, Reiner, Alex P., Tracy, Russell P., Ngo, Debby, Gerszten, Robert E., O'Neal, Wanda K., Bowler, Russell P.

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Plasma sRAGE levels strongly associate with centrilobular emphysema assessed by HRCT scans von Klont, Frank, Horvatovich, Peter, Bowler, Russell P, van Rikxoort, Eva, Charbonnier, Jean-Paul, Kwiatkowski, Marcel, Lynch, David A, Humphries, Stephen, Bischoff, Rainer, Ten Hacken, Nick H T, Pouwels, Simon D

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Lower serum IgA is associated with COPD exacerbation risk in SPIROMICS von Putcha, Nirupama, Paul, Gabriel G, Azar, Antoine, Wise, Robert A, O'Neal, Wanda K, Dransfield, Mark T, Woodruff, Prescott G, Curtis, Jeffrey L, Comellas, Alejandro P, Drummond, M Bradley, Lambert, Allison A, Paulin, Laura M, Fawzy, Ashraf, Kanner, Richard E, Paine, 3rd, Robert, Han, MeiLan K, Martinez, Fernando J, Bowler, Russell P, Barr, R Graham, Hansel, Nadia N

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Whole genome sequencing based analysis of inflammation biomarkers in the Trans-Omics for Precision Medicine (TOPMed) consortium von Jiang, Min-Zhi, Gaynor, Sheila M, Li, Xihao, Van Buren, Eric, Stilp, Adrienne, Buth, Erin, Wang, Fei Fei, Manansala, Regina, Gogarten, Stephanie M, Li, Zilin, Polfus, Linda M, Salimi, Shabnam, Bis, Joshua C, Pankratz, Nathan, Yanek, Lisa R, Durda, Peter, Tracy, Russell P, Rich, Stephen S, Rotter, Jerome I, Mitchell, Braxton D, Lewis, Joshua P, Psaty, Bruce M, Pratte, Katherine A, Silverman, Edwin K, Kaplan, Robert C, Avery, Christy, North, Kari E, Mathias, Rasika A, Faraday, Nauder, Lin, Honghuang, Wang, Biqi, Carson, April P, Norwood, Arnita F, Gibbs, Richard A, Kooperberg, Charles, Lundin, Jessica, Peters, Ulrike, Dupuis, Josée, Hou, Lifang, Fornage, Myriam, Benjamin, Emelia J, Reiner, Alexander P, Bowler, Russell P, Lin, Xihong, Auer, Paul L, Raffield, Laura M

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Assessing the contribution of rare variants to complex trait heritability from whole-genome sequence data von Wainschtein, Pierrick, Jain, Deepti, Zheng, Zhili, Cupples, L. Adrienne, Shadyab, Aladdin H., McKnight, Barbara, Shoemaker, Benjamin M., Mitchell, Braxton D., Psaty, Bruce M., Kooperberg, Charles, Liu, Ching-Ti, Albert, Christine M., Roden, Dan, Chasman, Daniel I., Darbar, Dawood, Lloyd-Jones, Donald M., Arnett, Donna K., Regan, Elizabeth A., Boerwinkle, Eric, Rotter, Jerome I., O’Connell, Jeffrey R., Yanek, Lisa R., de Andrade, Mariza, Allison, Matthew A., McDonald, Merry-Lynn N., Chung, Mina K., Fornage, Myriam, Chami, Nathalie, Smith, Nicholas L., Ellinor, Patrick T., Vasan, Ramachandran S., Mathias, Rasika A., Loos, Ruth J. F., Rich, Stephen S., Lubitz, Steven A., Heckbert, Susan R., Redline, Susan, Guo, Xiuqing, Chen, Y. -D Ida, Laurie, Cecelia A., Hernandez, Ryan D., McGarvey, Stephen T., Goddard, Michael E., Laurie, Cathy C., North, Kari E., Lange, Leslie A., Weir, Bruce S., Yengo, Loic, Yang, Jian, Visscher, Peter M.

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Clonal haematopoiesis and risk of chronic liver disease von Wong, Waihay J., Emdin, Connor, Bick, Alexander G., Zekavat, Seyedeh M., Niroula, Abhishek, Pirruccello, James P., Dichtel, Laura, Griffin, Gabriel, Uddin, Md Mesbah, Gibson, Christopher J., Kovalcik, Veronica, Lin, Amy E., McConkey, Marie E., Vromman, Amelie, Sellar, Rob S., Kim, Peter G., Agrawal, Mridul, Weinstock, Joshua, Long, Michelle T., Yu, Bing, Banerjee, Rajarshi, Nicholls, Rowan C., Dennis, Andrea, Kelly, Matt, Loh, Po-Ru, McCarroll, Steve, Boerwinkle, Eric, Vasan, Ramachandran S., Jaiswal, Siddhartha, Johnson, Andrew D., Chung, Raymond T., Corey, Kathleen, Levy, Daniel, Ballantyne, Christie, Ebert, Benjamin L., Natarajan, Pradeep

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Whole genome sequence association with E-selectin levels reveals loss-of-function variant in African Americans von Polfus, Linda M, Raffield, Laura M, Wheeler, Marsha M, Tracy, Russell P, Lange, Leslie A, Lettre, Guillaume, Miller, Amanda, Correa, Adolfo, Bowler, Russell P, Bis, Joshua C, Salimi, Shabnam, Jenny, Nancy Swords, Pankratz, Nathan, Wang, Biqi, Preuss, Michael H, Zhou, Lisheng, Moscati, Arden, Nadkarni, Girish N, Loos, Ruth J F, Zhong, Xue, Li, Bingshan, Johnsen, Jill M, Nickerson, Deborah A, Reiner, Alex P, Auer, Paul L

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Whole Genome Sequence Analysis of the Plasma Proteome in Black Adults Provides Novel Insights Into Cardiovascular Disease von Katz, Daniel H., Tahir, Usman A., Bick, Alexander G., Pampana, Akhil, Ngo, Debby, Benson, Mark D., Yu, Zhi, Robbins, Jeremy M., Chen, Zsu-Zsu, Cruz, Daniel E., Deng, Shuliang, Farrell, Laurie, Sinha, Sumita, Schmaier, Alec A., Shen, Dongxiao, Gao, Yan, Hall, Michael E., Correa, Adolfo, Tracy, Russell P., Durda, Peter, Taylor, Kent D., Liu, Yongmei, Johnson, W. Craig, Guo, Xiuqing, Yao, Jie, Ida Chen, Yii-Der, Manichaikul, Ani W., Jain, Deepti, Bouchard, Claude, Sarzynski, Mark A., Rich, Stephen S., Rotter, Jerome I., Wang, Thomas J., Wilson, James G., Natarajan, Pradeep, Gerszten, Robert E.

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Genetic landscape of chronic obstructive pulmonary disease identifies heterogeneous cell-type and phenotype associations von Sakornsakolpat, Phuwanat, Prokopenko, Dmitry, Lamontagne, Maxime, Reeve, Nicola F., Guyatt, Anna L., Jackson, Victoria E., Shrine, Nick, Qiao, Dandi, Bartz, Traci M., Kim, Deog Kyeom, Lee, Mi Kyeong, Latourelle, Jeanne C., Li, Xingnan, Morrow, Jarrett D., Obeidat, Ma’en, Wyss, Annah B., Bakke, Per, Barr, R. Graham, Beaty, Terri H., Belinsky, Steven A., Brusselle, Guy G., Crapo, James D., de Jong, Kim, DeMeo, Dawn L., Fingerlin, Tasha E., Gharib, Sina A., Gulsvik, Amund, Hall, Ian P., Hokanson, John E., Kim, Woo Jin, Lomas, David A., London, Stephanie J., Meyers, Deborah A., O’Connor, George T., Rennard, Stephen I., Schwartz, David A., Sliwinski, Pawel, Sparrow, David, Strachan, David P., Tal-Singer, Ruth, Tesfaigzi, Yohannes, Vestbo, Jørgen, Vonk, Judith M., Yim, Jae-Joon, Zhou, Xiaobo, Bossé, Yohan, Manichaikul, Ani, Lahousse, Lies, Silverman, Edwin K., Boezen, H. Marike, Wain, Louise V., Tobin, Martin D., Hobbs, Brian D., Cho, Michael H.

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A high-resolution HLA reference panel capturing global population diversity enables multi-ancestry fine-mapping in HIV host response von Luo, Yang, Kanai, Masahiro, Choi, Wanson, Li, Xinyi, Sakaue, Saori, Yamamoto, Kenichi, Ogawa, Kotaro, Gutierrez-Arcelus, Maria, Gregersen, Peter K., Stuart, Philip E., Elder, James T., Forer, Lukas, Schönherr, Sebastian, Fuchsberger, Christian, Smith, Albert V., Fellay, Jacques, Carrington, Mary, Haas, David W., Guo, Xiuqing, Palmer, Nicholette D., Chen, Yii-Der Ida, Rotter, Jerome I., Taylor, Kent D., Rich, Stephen S., Correa, Adolfo, Wilson, James G., Kathiresan, Sekar, Cho, Michael H., Metspalu, Andres, Esko, Tonu, Okada, Yukinori, Han, Buhm, McLaren, Paul J., Raychaudhuri, Soumya

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Dynamic incorporation of multiple in silico functional annotations empowers rare variant association analysis of large whole-genome sequencing studies at scale von Li, Xihao, Li, Zilin, Zhou, Hufeng, Gaynor, Sheila M., Liu, Yaowu, Chen, Han, Sun, Ryan, Dey, Rounak, Arnett, Donna K., Aslibekyan, Stella, Ballantyne, Christie M., Bielak, Lawrence F., Blangero, John, Boerwinkle, Eric, Bowden, Donald W., Broome, Jai G., Conomos, Matthew P., Correa, Adolfo, Cupples, L. Adrienne, Curran, Joanne E., Freedman, Barry I., Guo, Xiuqing, Hindy, George, Irvin, Marguerite R., Kardia, Sharon L. R., Kathiresan, Sekar, Khan, Alyna T., Kooperberg, Charles L., Laurie, Cathy C., Liu, X. Shirley, Mahaney, Michael C., Manichaikul, Ani W., Martin, Lisa W., Mathias, Rasika A., McGarvey, Stephen T., Mitchell, Braxton D., Montasser, May E., Moore, Jill E., Morrison, Alanna C., O’Connell, Jeffrey R., Palmer, Nicholette D., Pampana, Akhil, Peralta, Juan M., Peyser, Patricia A., Psaty, Bruce M., Redline, Susan, Rice, Kenneth M., Rich, Stephen S., Smith, Jennifer A., Tiwari, Hemant K., Tsai, Michael Y., Vasan, Ramachandran S., Wang, Fei Fei, Weeks, Daniel E., Weng, Zhiping, Wilson, James G., Yanek, Lisa R., Neale, Benjamin M., Sunyaev, Shamil R., Abecasis, Gonçalo R., Rotter, Jerome I., Willer, Cristen J., Peloso, Gina M., Natarajan, Pradeep, Lin, Xihong

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Longitudinal Phenotypes and Mortality in Preserved Ratio Impaired Spirometry in the COPDGene Study von Wan, Emily S, Fortis, Spyridon, Regan, Elizabeth A, Hokanson, John, Han, MeiLan K, Casaburi, Richard, Make, Barry J, Crapo, James D, DeMeo, Dawn L, Silverman, Edwin K

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Occupational exposures are associated with worse morbidity in patients with chronic obstructive pulmonary disease von Paulin, Laura M, Diette, Gregory B, Blanc, Paul D, Putcha, Nirupama, Eisner, Mark D, Kanner, Richard E, Belli, Andrew J, Christenson, Stephanie, Tashkin, Donald P, Han, MeiLan, Barr, R Graham, Hansel, Nadia N

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Aberrant activation of TCL1A promotes stem cell expansion in clonal haematopoiesis von Weinstock, Joshua S., Gopakumar, Jayakrishnan, Burugula, Bala Bharathi, Jahn, Nikolaus, Belk, Julia A., Bouzid, Hind, Daniel, Bence, Miao, Zhuang, Ly, Nghi, Mack, Taralynn M., Luna, Sofia E., Prothro, Katherine P., Mitchell, Shaneice R., Laurie, Cecelia A., Broome, Jai G., Taylor, Kent D., Guo, Xiuqing, Sinner, Moritz F., von Falkenhausen, Aenne S., Shuldiner, Alan R., O’Connell, Jeffrey R., Lewis, Joshua P., Boerwinkle, Eric, Chami, Nathalie, Kenny, Eimear E., Loos, Ruth J. F., Fornage, Myriam, Hou, Lifang, Lloyd-Jones, Donald M., Redline, Susan, Cade, Brian E., Psaty, Bruce M., Bis, Joshua C., Brody, Jennifer A., Yun, Jeong H., Qiao, Dandi, Palmer, Nicholette D., Freedman, Barry I., Bowden, Donald W., Cho, Michael H., Vasan, Ramachandran S., Yanek, Lisa R., Becker, Lewis C., Kardia, Sharon L. R., Peyser, Patricia A., He, Jiang, Rienstra, Michiel, Van der Harst, Pim, Kaplan, Robert, Heckbert, Susan R., Smith, Nicholas L., Wiggins, Kerri L., Arnett, Donna K., Irvin, Marguerite R., Tiwari, Hemant, Cutler, Michael J., Knight, Stacey, Muhlestein, J. Brent, Correa, Adolfo, Raffield, Laura M., Gao, Yan, de Andrade, Mariza, Rotter, Jerome I., Rich, Stephen S., Konkle, Barbara A., Johnsen, Jill M., Wheeler, Marsha M., Smith, J. Gustav, Melander, Olle, Nilsson, Peter M., Custer, Brian S., Duggirala, Ravindranath, Curran, Joanne E., Blangero, John, Xiao, Shujie, Yang, Mao, Gu, C. Charles, Chen, Yii-Der Ida, Lee, Wen-Jane, Marcus, Gregory M., Kane, John P., Pullinger, Clive R., Shoemaker, M. Benjamin, Darbar, Dawood, Roden, Dan M., Kooperberg, Charles, Zhou, Ying, Manson, JoAnn E., Desai, Pinkal, Johnson, Andrew D., Mathias, Rasika A., Abecasis, Goncalo R., Kang, Hyun M., Satpathy, Ansuman T., Natarajan, Pradeep, Kitzman, Jacob O., Whitsel, Eric A., Reiner, Alexander P., Bick, Alexander G., Jaiswal, Siddhartha

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Deep-coverage whole genome sequences and blood lipids among 16,324 individuals von Natarajan, Pradeep, Peloso, Gina M., Zekavat, Seyedeh Maryam, Montasser, May, Ganna, Andrea, Chaffin, Mark, Khera, Amit V., Zhou, Wei, Bloom, Jonathan M., Engreitz, Jesse M., Ernst, Jason, O’Connell, Jeffrey R., Ruotsalainen, Sanni E., Alver, Maris, Manichaikul, Ani, Johnson, W. Craig, Perry, James A., Poterba, Timothy, Seed, Cotton, Surakka, Ida L., Esko, Tonu, Ripatti, Samuli, Salomaa, Veikko, Correa, Adolfo, Vasan, Ramachandran S., Kellis, Manolis, Neale, Benjamin M., Lander, Eric S., Abecasis, Goncalo, Mitchell, Braxton, Rich, Stephen S., Wilson, James G., Cupples, L. Adrienne, Rotter, Jerome I., Willer, Cristen J., Kathiresan, Sekar

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A framework for detecting noncoding rare-variant associations of large-scale whole-genome sequencing studies von Li, Zilin, Li, Xihao, Zhou, Hufeng, Gaynor, Sheila M., Selvaraj, Margaret Sunitha, Arapoglou, Theodore, Quick, Corbin, Liu, Yaowu, Chen, Han, Sun, Ryan, Dey, Rounak, Arnett, Donna K., Auer, Paul L., Bielak, Lawrence F., Bis, Joshua C., Blackwell, Thomas W., Blangero, John, Boerwinkle, Eric, Bowden, Donald W., Brody, Jennifer A., Cade, Brian E., Conomos, Matthew P., Correa, Adolfo, Cupples, L. Adrienne, Curran, Joanne E., de Vries, Paul S., Duggirala, Ravindranath, Franceschini, Nora, Freedman, Barry I., Göring, Harald H. H., Guo, Xiuqing, Kalyani, Rita R., Kooperberg, Charles, Kral, Brian G., Lange, Leslie A., Lin, Bridget M., Manichaikul, Ani, Manning, Alisa K., Martin, Lisa W., Mathias, Rasika A., Meigs, James B., Mitchell, Braxton D., Montasser, May E., Morrison, Alanna C., Naseri, Take, O’Connell, Jeffrey R., Palmer, Nicholette D., Peyser, Patricia A., Psaty, Bruce M., Raffield, Laura M., Redline, Susan, Reiner, Alexander P., Reupena, Muagututi’a Sefuiva, Rice, Kenneth M., Rich, Stephen S., Smith, Jennifer A., Taylor, Kent D., Taub, Margaret A., Vasan, Ramachandran S., Weeks, Daniel E., Wilson, James G., Yanek, Lisa R., Zhao, Wei, Rotter, Jerome I., Willer, Cristen J., Natarajan, Pradeep, Peloso, Gina M., Lin, Xihong

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Efficient Variant Set Mixed Model Association Tests for Continuous and Binary Traits in Large-Scale Whole-Genome Sequencing Studies von Chen, Han, Huffman, Jennifer E., Brody, Jennifer A., Wang, Chaolong, Lee, Seunggeun, Li, Zilin, Gogarten, Stephanie M., Sofer, Tamar, Bielak, Lawrence F., Bis, Joshua C., Blangero, John, Bowler, Russell P., Cade, Brian E., Cho, Michael H., Correa, Adolfo, Curran, Joanne E., de Vries, Paul S., Glahn, David C., Guo, Xiuqing, Johnson, Andrew D., Kardia, Sharon, Kooperberg, Charles, Lewis, Joshua P., Liu, Xiaoming, Mathias, Rasika A., Mitchell, Braxton D., O’Connell, Jeffrey R., Peyser, Patricia A., Post, Wendy S., Reiner, Alex P., Rich, Stephen S., Rotter, Jerome I., Silverman, Edwin K., Smith, Jennifer A., Vasan, Ramachandran S., Wilson, James G., Yanek, Lisa R., Redline, Susan, Smith, Nicholas L., Boerwinkle, Eric, Borecki, Ingrid B., Cupples, L. Adrienne, Laurie, Cathy C., Morrison, Alanna C., Rice, Kenneth M., Lin, Xihong

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Prediction of Acute Respiratory Disease in Current and Former Smokers With and Without COPD von Bowler, Russell P., MD, PhD, Kim, Victor, MD, Regan, Elizabeth, MD, Williams, André A.A., PhD, Santorico, Stephanie A., PhD, Make, Barry J., MD, FCCP, Lynch, David A., MD, Hokanson, John E., PhD, Washko, George R., MD, Bercz, Peter, MD, Soler, Xavier, MD, Marchetti, Nathaniel, MD, FCCP, Criner, Gerard J., MD, FCCP, Ramsdell, Joe, MD, FCCP, Han, MeiLan K., MD, Demeo, Dawn, MD, Anzueto, Antonio, MD, Comellas, Alejandro, MD, Crapo, James D., MD, FCCP, Dransfield, Mark, MD, Wells, J. Michael, MD, Hersh, Craig P., MD, MacIntyre, Neil, MD, FCCP, Martinez, Fernando, MD, FCCP, Nath, Hrudaya P., MD, FCCP, Niewoehner, Dennis, MD, FCCP, Sciurba, Frank, MD, FCCP, Sharafkhaneh, Amir, MD, FCCP, Silverman, Edwin K., MD, PhD, van Beek, Edwin J.R., MD, Wilson, Carla, Wendt, Christine, MD, Wise, Robert A., MD, FCCP

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