Escherichia coli cells evade inducible parE toxin expression by reducing plasmid copy number von Ruan, Shengfeng, Bourne, Christina R

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Toxin-Antitoxin Modules Are Pliable Switches Activated by Multiple Protease Pathways von Muthuramalingam, Meenakumari, White, John C, Bourne, Christina R

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A YoeB toxin cleaves both RNA and DNA von McGillick, Julia, Ames, Jessica R., Murphy, Tamiko, Bourne, Christina R.

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Friend or Foe: Protein Inhibitors of DNA Gyrase von Ruan, Shengfeng, Tu, Chih-Han, Bourne, Christina R

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Utility of the Biosynthetic Folate Pathway for Targets in Antimicrobial Discovery von Bourne, Christina R

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Global Structural Changes in Hepatitis B Virus Capsids Induced by the Assembly Effector HAP1 von BOURNE, Christina R, FINN, M. G, ZLOTNICK, Adam

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Identifying a Molecular Mechanism That Imparts Species-Specific Toxicity to YoeB Toxins von Ames, Jessica R., McGillick, Julia, Murphy, Tamiko, Reddem, Eswar, Bourne, Christina R.

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A Heteroaryldihydropyrimidine Activates and Can Misdirect Hepatitis B Virus Capsid Assembly von Stray, Stephen J., Bourne, Christina R., Punna, Sreenivas, Lewis, Warren G., Finn, M. G., Zlotnick, Adam, Summers, Jesse

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Bacterial Growth Mindset: Structural Plasticity in Defense Systems von Bourne, Christina R

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Identification of Novel Potential Antibiotics against Staphylococcus Using Structure-Based Drug Screening Targeting Dihydrofolate Reductase von Kobayashi, Maiko, Kinjo, Tomohiro, Koseki, Yuji, Bourne, Christina R, Barrow, William W, Aoki, Shunsuke

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Expression of different ParE toxins results in conserved phenotypes with distinguishable classes of toxicity von Ames, Jessica R., Muthuramalingam, Meenakumari, Murphy, Tamiko, Najar, Fares Z., Bourne, Christina R.

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Crystal Structure of Bacillus anthracis Dihydrofolate Reductase with the Dihydrophthalazine-Based Trimethoprim Derivative RAB1 Provides a Structural Explanation of Potency and Sele... von BOURNE, Christina R, BUNCE, Richard A, BOURNE, Philip C, DARRELL BERLIN, K, BARROW, Esther W, BARROW, William W

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ParD Antitoxin Hotspot Alters a Disorder-to-Order Transition upon Binding to Its Cognate ParE Toxin, Lessening Its Interaction Affinity and Increasing Its Protease Degradation Kine... von Snead, Kevin J, Moore, Landon L, Bourne, Christina R

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The toxin from a ParDE toxin‐antitoxin system found in Pseudomonas aeruginosa offers protection to cells challenged with anti‐gyrase antibiotics von Muthuramalingam, Meenakumari, White, John C., Murphy, Tamiko, Ames, Jessica R., Bourne, Christina R.

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Evaluation of New Dihydrophthalazine-Appended 2,4-Diaminopyrimidines against Bacillus anthracis: Improved Syntheses Using a New Pincer Complex von Muddala, Nagendra Prasad, Nammalwar, Baskar, Selvaraju, Subhashini, Bourne, Christina R, Henry, Mary, Bunce, Richard A, Berlin, K Darrell, Barrow, Esther W, Barrow, William W

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Synthesis and biological evaluation of 2,4-diaminopyrimidine-based antifolate drugs against Bacillus anthracis von Nammalwar, Baskar, Muddala, N Prasad, Bourne, Christina R, Henry, Mary, Bourne, Philip C, Bunce, Richard A, Barrow, Esther W, Berlin, K Darrell, Barrow, William W

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Molecular Basis for the Substrate Promiscuity of Isopentenyl Phosphate Kinase from Candidatus methanomethylophilus alvus von Johnson, Bryce P, Kumar, Vikas, Scull, Erin M, Thomas, Leonard M, Bourne, Christina R, Singh, Shanteri

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Crystal structure of a glycosylated Fab from an IgM cryoglobulin with properties of a natural proteolytic antibody von Ramsland, Paul A, Terzyan, Simon S, Cloud, Gwendolyn, Bourne, Christina R, Farrugia, William, Tribbick, Gordon, Geysen, H Mario, Moomaw, Carolyn R, Slaughter, Clive A, Edmundson, Allen B

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Inhibitor design to target a unique feature in the folate pocket of Staphylococcus aureus dihydrofolate reductase von Muddala, N. Prasad, White, John C., Nammalwar, Baskar, Pratt, Ian, Thomas, Leonard M., Bunce, Richard A., Berlin, K. Darrell, Bourne, Christina R.

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Structure–Activity Relationships of Ligand Binding to Oxysterol-Binding Protein (OSBP) and OSBP-Related Protein 4 von Severance, Zachary C., Nuñez, Juan I., Le-McClain, Anh T., Malinky, Cori A., Bensen, Ryan C., Fogle, Robert S., Manginelli, Gianni W., Sakers, Sophia H., Falcon, Emily C., Bui, Richard Hoang, Snead, Kevin J., Bourne, Christina R., Burgett, Anthony W. G.

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