Living on the edge: how stromal cells restrict liver cancer invasion von Boulter, Luke

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Cholangiocytes act as facultative liver stem cells during impaired hepatocyte regeneration von Raven, Alexander, Lu, Wei-Yu, Man, Tak Yung, Ferreira-Gonzalez, Sofia, O’Duibhir, Eoghan, Dwyer, Benjamin J., Thomson, John P., Meehan, Richard R., Bogorad, Roman, Koteliansky, Victor, Kotelevtsev, Yuri, ffrench-Constant, Charles, Boulter, Luke, Forbes, Stuart J.

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NOTCH signalling - a core regulator of bile duct disease? von Martinez Lyons, Anabel, Boulter, Luke

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Paracrine cellular senescence exacerbates biliary injury and impairs regeneration von Ferreira-Gonzalez, Sofia, Lu, Wei-Yu, Raven, Alexander, Dwyer, Benjamin, Man, Tak Yung, O’Duibhir, Eoghan, Lewis, Philip J. Starkey, Campana, Lara, Kendall, Tim J., Bird, Thomas G., Tarrats, Nuria, Acosta, Juan-Carlos, Boulter, Luke, Forbes, Stuart J.

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Macrophage-derived Wnt opposes Notch signaling to specify hepatic progenitor cell fate in chronic liver disease von Boulter, Luke, Govaere, Olivier, Bird, Tom G, Radulescu, Sorina, Ramachandran, Prakash, Pellicoro, Antonella, Ridgway, Rachel A, Seo, Sang Soo, Spee, Bart, Van Rooijen, Nico, Sansom, Owen J, Iredale, John P, Lowell, Sally, Roskams, Tania, Forbes, Stuart J

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Differential Ly-6C expression identifies the recruited macrophage phenotype, which orchestrates the regression of murine liver fibrosis von Ramachandran, Prakash, Pellicoro, Antonella, Vernon, Madeleine A., Boulter, Luke, Aucott, Rebecca L., Ali, Aysha, Hartland, Stephen N., Snowdon, Victoria K., Cappon, Andrea, Gordon-Walker, Timothy T., Williams, Mike J., Dunbar, Donald R., Manning, Jonathan R., van Rooijen, Nico, Fallowfield, Jonathan A., Forbes, Stuart J., Iredale, John P.

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EpCAM and the biology of hepatic stem/progenitor cells von Dollé, Laurent, Theise, Neil D, Schmelzer, Eva, Boulter, Luke, Gires, Olivier, van Grunsven, Leo A

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Differentiation of progenitors in the liver: a matter of local choice von Boulter, Luke, Lu, Wei-Yu, Forbes, Stuart J

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The developmental origins of Notch-driven intrahepatic bile duct disorders von Lyons, Anabel Martinez, Boulter, Luke

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Cell Lineage Tracing Reveals a Biliary Origin of Intrahepatic Cholangiocarcinoma von GUEST, Rachel V, BOULTER, Luke, KENDALL, Timothy J, MINNIS-LYONS, Sarah E, WALKER, Robert, WIGMORE, Stephen J, SANSOM, Owen J, FORBES, Stuart J

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Bone marrow injection stimulates hepatic ductular reactions in the absence of injury via macrophage-mediated TWEAK signaling von Bird, Thomas G., Lu, Wei-Yu, Boulter, Luke, Gordon-Keylock, Sabrina, Ridgway, Rachel A., Williams, Michael J., Taube, Jessica, Thomas, James A., Wojtacha, Davina, Gambardella, Adriana, Sansom, Owen J., Iredale, John P., Forbes, Stuart J.

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Notch3 drives development and progression of cholangiocarcinoma von Guest, Rachel V., Boulter, Luke, Dwyer, Benjamin J., Kendall, Timothy J., Man, Tak-Yung, Minnis-Lyons, Sarah E., Lu, Wei-Yu, Robson, Andrew J., Gonzalez, Sofia Ferreira, Raven, Alexander, Wojtacha, Davina, Morton, Jennifer P., Komuta, Mina, Roskams, Tania, Wigmore, Stephen J., Sansom, Owen J., Forbes, Stuart J.

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Embryonic mesothelial-derived hepatic lineage of quiescent and heterogenous scar-orchestrating cells defined but suppressed by WT1 von Kendall, Timothy James, Duff, Catherine Mary, Boulter, Luke, Wilson, David H., Freyer, Elisabeth, Aitken, Stuart, Forbes, Stuart John, Iredale, John Peter, Hastie, Nicholas Dixon

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In Vivo Modeling of Patient Genetic Heterogeneity Identifies New Ways to Target Cholangiocarcinoma von Younger, Nicholas T, Wilson, Mollie L, Martinez Lyons, Anabel, Jarman, Edward J, Meynert, Alison M, Grimes, Graeme R, Gournopanos, Konstantinos, Waddell, Scott H, Tennant, Peter A, Wilson, David H, Guest, Rachel V, Wigmore, Stephen J, Acosta, Juan Carlos, Kendall, Timothy J, Taylor, Martin S, Sproul, Duncan, Mill, Pleasantine, Boulter, Luke

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Thymic epithelial cell fate and potency in early organogenesis assessed by single cell transcriptional and functional analysis von Farley, Alison Mary, Chengrui, An, Palmer, Sam, Liu, Dong, Kousa, Anastasia I, Rouse, Paul, Major, Viktoria, Sweetman, Joanna, Morys, Jan, Corsinotti, Andrea, Nichols, Jennifer, Ure, Janice, McLay, Renee, Boulter, Luke, Chapman, S Jon, Tomlinson, Simon R, Blackburn, C Clare

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Inhibition of nuclear factor (erythroid-derived 2)-like 2 promotes hepatic progenitor cell activation and differentiation von Bellanti, Francesco, di Bello, Giorgia, Iannelli, Giuseppina, Pannone, Giuseppe, Pedicillo, Maria Carmela, Boulter, Luke, Lu, Wei-Yu, Tamborra, Rosanna, Villani, Rosanna, Vendemiale, Gianluigi, Forbes, Stuart J., Serviddio, Gaetano

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FRI-158-YI The cyst microenvironment is spatially patterned to promote polycystic liver disease von Waddell, Scott, Yao, Yuelin, Boulter, Luke

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Joining the dots – NEDDylation in cancer cells regulates the tumour environment in cholangiocarcinoma von Lüdde, Tom, Boulter, Luke

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FRI-463-YI Identifying unique cell states in early liver oncogenesis with transcription coupled repair von Carmichael, Elizabeth, Jarman, Edward, Boulter, Luke, Taylor, Martin

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The fibrotic and immune microenvironments as targetable drivers of metastasis von Boulter, Luke, Bullock, Esme, Mabruk, Zeanap, Brunton, Valerie G.

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