Ehlers-Danlos Syndrome with Severe Early-Onset Periodontal Disease (EDS-VIII) Is a Distinct, Heterogeneous Disorder with One Predisposition Gene at Chromosome 12p13 von Rahman, Nazneen, Dunstan, Melanie, Teare, M. Dawn, Hanks, Sandra, Douglas, Jenny, Coleman, Kim, Bottomly, William E., Campbell, Mary E., Berglund, Britta, Nordenskjöld, Magnus, Forssell, Bengt, Burrows, Nigel, Lunt, Peter, Young, Ian, Williams, Nigel, Bignell, Graham R., Futreal, P. Andrew, Pope, F. Michael

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The genome architecture of the Collaborative Cross mouse genetic reference population von Cross Consortium, Collaborative

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Discovery and characterization of targetable NTRK point mutations in hematologic neoplasms von Joshi, Sunil K., Qian, Kristin, Bisson, William H., Watanabe-Smith, Kevin, Huang, Ariane, Bottomly, Daniel, Traer, Elie, Tyner, Jeffrey W., McWeeney, Shannon K., Davare, Monika A., Druker, Brian J., Tognon, Cristina E.

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Disruption of the MYC Superenhancer Complex by Dual Targeting of FLT3 and LSD1 in Acute Myeloid Leukemia von Yashar, William M, Curtiss, Brittany M, Coleman, Daniel J, VanCampen, Jake, Kong, Garth, Macaraeg, Jommel, Estabrook, Joseph, Demir, Emek, Long, Nicola, Bottomly, Daniel, McWeeney, Shannon K, Tyner, Jeffrey W, Druker, Brian J, Maxson, Julia E, Braun, Theodore P

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Luxeptinib (CG-806) Targets FLT3 and Clusters of Kinases Operative in Acute Myeloid Leukemia von Rice, William G, Howell, Stephen B, Zhang, Hongying, Rastgoo, Nasrin, Local, Andrea, Kurtz, Stephen E, Lo, Pierrette, Bottomly, Daniel, Wilmot, Beth, McWeeney, Shannon K, Druker, Brian J, Tyner, Jeffrey W

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Disruption of the MYC Super-Enhancer Complex by Dual Targeting of FLT3 and LSD1 in Acute Myeloid Leukemia von Yashar, William M., Curtiss, Brittany M., Coleman, Daniel J., VanCampen, Jake, Kong, Garth, Macaraeg, Jommel, Estabrook, Joseph, Demir, Emek, Long, Nicola, Bottomly, Daniel, McWeeney, Shannon K., Tyner, Jeffrey W., Druker, Brian J., Maxson, Julia E., Braun, Theodore P.

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Modeling host genetic regulation of influenza pathogenesis in the collaborative cross von Ferris, Martin T, Aylor, David L, Bottomly, Daniel, Whitmore, Alan C, Aicher, Lauri D, Bell, Timothy A, Bradel-Tretheway, Birgit, Bryan, Janine T, Buus, Ryan J, Gralinski, Lisa E, Haagmans, Bart L, McMillan, Leonard, Miller, Darla R, Rosenzweig, Elizabeth, Valdar, William, Wang, Jeremy, Churchill, Gary A, Threadgill, David W, McWeeney, Shannon K, Katze, Michael G, Pardo-Manuel de Villena, Fernando, Baric, Ralph S, Heise, Mark T

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Abstract 791: CG'806, a first-in-class pan-FLT3/pan-BTK inhibitor, demonstrates superiority to other FLT3 and BTK inhibitors against primary patient samples von Kurtz, Stephen E., Watanabe-Smith, Kevin, Bottomly, Dan, Wilmot, Beth, Mcweeney, Shannon, Local, Andrea, Zhang, Hongying, Howell, Stephen, Rice, William, Druker, Brian J., Tyner, Jeffrey W.

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Broad Activity of Apto-253 in AML and Other Hematologic Malignancies Correlates with KLF4 Expression Level von Kurtz, Stephen E., Bottomly, Daniel, Wilmot, Beth, McWeeney, Shannon K., Rice, William, Howell, Stephen B, Vellanki, Avanish, Druker, Brian J., Tyner, Jeffrey W.

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Differences in the expression profiles of CD45RB, Pgp-1, and 3G11 membrane antigens and in the patterns of lymphokine secretion by splenic CD4+ T cells from young and aged mice von Ernst, DN, Hobbs, MV, Torbett, BE, Glasebrook, AL, Rehse, MA, Bottomly, K, Hayakawa, K, Hardy, RR, Weigle, WO

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Cell proliferation and cytokine production by CD4+ cells from old mice von Hobbs, Monte V., Ernst, David N., Torbett, Bruce E., Glasebrook, Andrew L., Rehse, Mark A., McQuitty, Donald N., Thoman, Marilyn L., Bottomly, Kim, Rothermel, Annette L., Noonan, Daniel J., Weigle, William O.

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