The role of matrix metalloproteinases (MMPs) in the pathophysiology of chronic obstructive pulmonary disease (COPD): a therapeutic role for inhibitors of MMPs? von Belvisi, M G, Bottomley, K M

Volltext

Ro 32‐3555, an orally active collagenase inhibitor, prevents cartilage breakdown in vitro and in vivo von Lewis, E. J., Bishop, J., Bottomley, K. M. K., Bradshaw, D., Brewster, M., Broadhurst, M. J., Brown, P. A., Budd, J. M., Elliott, L., Greenham, A. K., Johnson, W. H., Nixon, J. S., Rose, F., Sutton, B., Wilson, K.

Volltext

Inhibition of bone resorption in vitro by selective inhibitors of gelatinase and collagenase von Hill, P A, Docherty, A J, Bottomley, K M, O'Connell, J P, Morphy, J R, Reynolds, J J, Meikle, M C

Volltext

Matrix Metalloproteinase Inhibitors in Arthritis von Bottomley, K. M., Johnson, W. H., Walter, D. S.

Volltext

Metalloproteinase inhibitors: new opportunities for the treatment of rheumatoid arthritis and osteoarthritis von Shaw, Tim, Nixon, John S, Bottomley, Kevin M

Volltext

A modified mouse air pouch model for evaluating the effects of compounds on granuloma induced cartilage degradation von Bottomley, K.M.K., Griffiths, R.J., Rising, T.J., Steward, A.

Volltext

Ro 32‐3555, an orally active collagenase selective inhibitor, prevents structural damage in the STR/ORT mouse model of osteoarthritis von Brewster, Michael, Lewis, Jonathan E., Wilson, Kevin L., Greenham, Anna K., Bottomley, Kevin M. K.

Volltext

Inhibition of bovine nasal cartilage degradation by selective matrix metalloproteinase inhibitors von Bottomley, K M, Borkakoti, N, Bradshaw, D, Brown, P A, Broadhurst, M J, Budd, J M, Elliott, L, Eyers, P, Hallam, T J, Handa, B K, Hill, C H, James, M, Lahm, H W, Lawton, G, Merritt, J E, Nixon, J S, Röthlisberger, U, Whittle, A, Johnson, W H

Volltext

Design and synthesis of the cartilage protective agent (CPA, Ro32-3555) von Broadhurst, M.J., Brown, P.A., Lawton, G., Ballantyne, N., Borkakoti, N., Bottomley, K.M.K., Cooper, M.I., Eatherton, A.J., Kilford, I.R., Malsher, P.J., Nixon, J.S., Lewis, E.J., Sutton, B.M., Johnson, W.H.

Volltext

A new in vivo method for the measurement of repetitive anaphylactic responses in the guinea‐pig von Bottomley, Kevin M.K., Lewis, Stevan, Rising, Trevor J., Steward, Alan

Volltext

Low level antigen responses in guinea-pig lung strip von Steward, A., Bottomley, K. M. K., Lewis, S., Rising, T. J.

Volltext

Efficacy and safety of radium-223 dichloride in patients with castration-resistant prostate cancer and symptomatic bone metastases, with or without previous docetaxel use: a prespe... von Hoskin, Peter, Prof, Sartor, Oliver, Prof, O'Sullivan, Joe M, Prof, Johannessen, Dag Clement, MD, Helle, Svein I, MD, Logue, John, FRCR, Bottomley, David, FRCR, Nilsson, Sten, Prof, Vogelzang, Nicholas J, Prof, Fang, Fang, PhD, Wahba, Mona, MD, Aksnes, Anne-Kirsti, PhD, Parker, Christopher, MD

Volltext

The development of the EORTC QLQ-C15-PAL: A shortened questionnaire for cancer patients in palliative care von Groenvold, Mogens, Petersen, Morten Aa, Aaronson, Neil K., Arraras, Juan I., Blazeby, Jane M., Bottomley, Andrew, Fayers, Peter M., de Graeff, Alexander, Hammerlid, Eva, Kaasa, Stein, Sprangers, Mirjam A.G., Bjorner, Jakob B.

Volltext

Adipose-Derived Stem Cells Spontaneously Express Neural Markers When Grown in a PEG-Based 3D Matrix von Gomila Pelegri, Neus, Stanczak, Aleksandra M, Bottomley, Amy L, Milthorpe, Bruce K, Gorrie, Catherine A, Padula, Matthew P, Santos, Jerran

Volltext

Timing of radiotherapy (RT) after radical prostatectomy (RP): long-term outcomes in the RADICALS-RT trial (NCT00541047) von Parker, C.C., Petersen, P.M., Cook, A.D., Clarke, N.W., Catton, C., Cross, W.R., Kynaston, H., Parulekar, W.R., Persad, R.A., Saad, F., Bower, L., Durkan, G.C., Logue, J., Maniatis, C., Noor, D., Payne, H., Anderson, J., Bahl, A.K., Bashir, F., Bottomley, D.M., Brasso, K., Capaldi, L., Chung, C., Cooke, P.W., Donohue, J.F., Eddy, B., Heath, C.M., Henderson, A., Henry, A., Jaganathan, R., Jakobsen, H., James, N.D., Joseph, J., Lees, K., Lester, J., Lindberg, H., Makar, A., Morris, S.L., Oommen, N., Ostler, P., Owen, L., Patel, P., Pope, A., Popert, R., Raman, R., Ramani, V., Røder, A., Sayers, I., Simms, M., Srinivasan, V., Sundaram, S., Tarver, K.L., Tran, A., Wells, P., Wilson, J., Zarkar, A.M., Parmar, M.K.B., Sydes, M.R.

Volltext

Prevalence of active convulsive epilepsy in sub-Saharan Africa and associated risk factors: cross-sectional and case-control studies von Ngugi, Anthony K, Dr, Bottomley, Christian, PhD, Kleinschmidt, Immo, PhD, Wagner, Ryan G, MSc, Kakooza-Mwesige, Angelina, MD, Ae-Ngibise, Kenneth, MSc, Owusu-Agyei, Seth, PhD, Masanja, Honorati, PhD, Kamuyu, Gathoni, MSc, Odhiambo, Rachael, BSc, Chengo, Eddie, MSc, Sander, Josemir W, Prof, Newton, Charles R, Prof

Volltext

Quantifying previous SARS-CoV-2 infection through mixture modelling of antibody levels von Bottomley, C., Otiende, M., Uyoga, S., Gallagher, K., Kagucia, E. W., Etyang, A. O., Mugo, D., Gitonga, J., Karanja, H., Nyagwange, J., Adetifa, I. M. O., Agweyu, A., Nokes, D. J., Warimwe, G. M., Scott, J. A. G.

Volltext

Mutations in TRNT1 cause congenital sideroblastic anemia with immunodeficiency, fevers, and developmental delay (SIFD) von Chakraborty, Pranesh K., Schmitz-Abe, Klaus, Kennedy, Erin K., Mamady, Hapsatou, Naas, Turaya, Durie, Danielle, Campagna, Dean R., Lau, Ashley, Sendamarai, Anoop K., Wiseman, Daniel H., May, Alison, Jolles, Stephen, Connor, Philip, Powell, Colin, Heeney, Matthew M., Giardina, Patricia-Jane, Klaassen, Robert J., Kannengiesser, Caroline, Thuret, Isabelle, Thompson, Alexis A., Marques, Laura, Hughes, Stephen, Bonney, Denise K., Bottomley, Sylvia S., Wynn, Robert F., Laxer, Ronald M., Minniti, Caterina P., Moppett, John, Bordon, Victoria, Geraghty, Michael, Joyce, Paul B.M., Markianos, Kyriacos, Rudner, Adam D., Holcik, Martin, Fleming, Mark D.

Volltext

Incidence of epilepsy: A systematic review and meta-analysis von NGUGI, A. K, KARIUKI, S. M, BOTTOMLEY, C, KLEINSCHMIDT, I, SANDER, J. W, NEWTON, C. R

Volltext

An international update of the EORTC questionnaire for assessing quality of life in breast cancer patients: EORTC QLQ-BR45 von Bjelic-Radisic, V., Cardoso, F., Cameron, D., Brain, E., Kuljanic, K., da Costa, R.A., Conroy, T., Inwald, E.C., Serpentini, S., Pinto, M., Weis, J., Morag, O., Lindviksmoen Astrup, G., Tomaszweksi, K.A., Pogoda, K., Sinai, P., Sprangers, M., Aaronson, N., Velikova, G., Greimel, E., Arraras, J., Bottomley, A., Bleiker, Eveline, Bliem, Brigitte, Chie, Weichu, Creutzberg, Carien, Deville, Valerie, Duhoux, Francois, Eilf, Kirsten, Hartup, Sue, Koller, Michael, Nagele, Eva, Nicolatou-Galitis, Ourania, Oberguggenberger, Anne, Schmalz, Claudia, Winters, Zoe

Volltext