Sirtuins - novel therapeutic targets to treat age-associated diseases von Lambert, Philip D, Lavu, Siva, Boss, Olivier, Elliott, Peter J

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Small molecule activators of SIRT1 as therapeutics for the treatment of type 2 diabetes von Choy, Wendy, Sinclair, David A, Lambert, Philip D, Gagne, David J, Lynch, Amy V, Milne, Jill C, Bemis, Jean E, Boss, Olivier, Perni, Robert B, Schenk, Simon, Carney, David P, Yang, Hongying, Ng, Pui Yee, Iffland, Andre, Smith, Jesse J, Elliott, Peter J, Vu, Chi B, Xie, Roger, Galonek, Heidi, Israelian, Kristine, Lavu, Siva, Medvedik, Oliver, Olefsky, Jerrold M, Disch, Jeremy S, Nunes, Joseph J, Jirousek, Michael R, Westphal, Christoph H, Jin, Lei

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Conserved role of SIRT1 orthologs in fasting-dependent inhibition of the lipid/cholesterol regulator SREBP von Walker, Amy K, Yang, Fajun, Jiang, Karen, Ji, Jun-Yuan, Watts, Jennifer L, Purushotham, Aparna, Boss, Olivier, Hirsch, Michael L, Ribich, Scott, Smith, Jesse J, Israelian, Kristine, Westphal, Christoph H, Rodgers, Joseph T, Shioda, Toshi, Elson, Sarah L, Mulligan, Peter, Najafi-Shoushtari, Hani, Black, Josh C, Thakur, Jitendra K, Kadyk, Lisa C, Whetstine, Johnathan R, Mostoslavsky, Raul, Puigserver, Pere, Li, Xiaoling, Dyson, Nicholas J, Hart, Anne C, Näär, Anders M

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Divergence of Melanocortin Pathways in the Control of Food Intake and Energy Expenditure von Balthasar, Nina, Dalgaard, Louise T., Lee, Charlotte E., Yu, Jia, Funahashi, Hisayuki, Williams, Todd, Ferreira, Manuel, Tang, Vinsee, McGovern, Robert A., Kenny, Christopher D., Christiansen, Lauryn M., Edelstein, Elizabeth, Choi, Brian, Boss, Olivier, Aschkenasi, Carl, Zhang, Chen-yu, Mountjoy, Kathleen, Kishi, Toshiro, Elmquist, Joel K., Lowell, Bradford B.

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Serotonin Reciprocally Regulates Melanocortin Neurons to Modulate Food Intake von Heisler, Lora K., Jobst, Erin E., Sutton, Gregory M., Zhou, Ligang, Borok, Erzsebet, Thornton-Jones, Zoe, Liu, Hong Yan, Zigman, Jeffrey M., Balthasar, Nina, Kishi, Toshiro, Lee, Charlotte E., Aschkenasi, Carl J., Zhang, Chen-Yu, Yu, Jia, Boss, Olivier, Mountjoy, Kathleen G., Clifton, Peter G., Lowell, Bradford B., Friedman, Jeffrey M., Horvath, Tamas, Butler, Andrew A., Elmquist, Joel K., Cowley, Michael A.

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Recruitment of brown adipose tissue as a therapy for obesity-associated diseases von Boss, Olivier, Farmer, Stephen R

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Adipose-selective targeting of the GLUT4 gene impairs insulin action in muscle and liver von Kahn, Barbara B, Peroni, Odile, Shulman, Gerald I, Kim, Young-Bum, Minnemann, Timo, Hadro, Ed, Kim, Jason K, Boss, Olivier, Abel, E. Dale

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Increased Energy Expenditure, Decreased Adiposity, and Tissue-Specific Insulin Sensitivity in Protein-Tyrosine Phosphatase 1B-Deficient Mice von Klaman, Lori D., Boss, Olivier, Peroni, Odile D., Kim, Jason K., Martino, Jennifer L., Zabolotny, Janice M., Moghal, Nadeem, Lubkin, Margaret, Kim, Young-Bum, Sharpe, Arlene H., Stricker-Krongrad, Alain, Shulman, Gerald I., Neel, Benjamin G., Kahn, Barbara B.

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The obesity epidemic : Current and future pharmacological treatments von HOFBAUER, Karl G, NICHOLSON, Janet R, BOSS, Olivier

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Small molecule activators of SIRT1 replicate signaling pathways triggered by calorie restriction in vivo von Smith, Jesse J, Kenney, Renée Deehan, Gagne, David J, Frushour, Brian P, Ladd, William, Galonek, Heidi L, Israelian, Kristine, Song, Jeffrey, Razvadauskaite, Giedre, Lynch, Amy V, Carney, David P, Johnson, Robin J, Lavu, Siva, Iffland, Andre, Elliott, Peter J, Lambert, Philip D, Elliston, Keith O, Jirousek, Michael R, Milne, Jill C, Boss, Olivier

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Energy Metabolism in Uncoupling Protein 3 Gene Knockout Mice von Vidal-Puig, Antonio J., Grujic, Danica, Zhang, Chen-Yu, Hagen, Thilo, Boss, Olivier, Ido, Yasuo, Szczepanik, Alicja, Wade, Jennifer, Mootha, Vamsi, Cortright, Ronald, Muoio, Deborah M., Lowell, Bradford B.

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Uncoupling Protein-3 Expression in Rodent Skeletal Muscle Is Modulated by Food Intake but Not by Changes in Environmental Temperature von Boss, Olivier, Samec, Sonia, Kühne, Françoise, Bijlenga, Philippe, Assimacopoulos-Jeannet, Françoise, Seydoux, Josiane, Giacobino, Jean-Paul, Muzzin, Patrick

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Tissue-dependent upregulation of rat uncoupling protein-2 expression in response to fasting or cold von Boss, Olivier, Samec, Sonia, Dulloo, Abdul, Seydoux, Josiane, Patrick Muzzin, Giacobino, Jean-Paul

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Overexpression of the LAR (Leukocyte Antigen-Related) Protein-Tyrosine Phosphatase in Muscle Causes Insulin Resistance von Zabolotny, Janice M., Kim, Young-Bum, Peroni, Odile D., Kim, Jason K., Pani, Michael A., Boss, Olivier, Klaman, Lori D., Kamatkar, Shubhangi, Shulman, Gerald I., Kahn, Barbara B., Neel, Benjamin G.

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Effect of endurance training on mRNA expression of uncoupling proteins 1, 2, and 3 in the rat von Boss, Olivier, Samec, Sonia, Desplanches, Dominique, Mayet, Marie‐HÉLÈNE, Seydoux, Josiane, Muzzin, Patrick, Giacobino, Jean‐Paul

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Targeting PGC-1α to control energy homeostasis von Wu, Zhidan, Boss, Olivier

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Resveratrol improves health and survival of mice on a high-calorie diet von Baur, J.A, Pearson, K.J, Price, N.L, Jamieson, H.A, Lerin, C, Kalra, A, Prabhu, V.V, Allard, J.S, Lopez-Lluch, G, Lewis, K

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Cloning and functional characterization of an uncoupling protein homolog in hummingbirds von VIANNA, CLAUDIA R, HAGEN, THILO, ZHANG, CHEN-YU, BACHMAN, ERIC, BOSS, OLIVIER, GEREBEN, BALAZS, MORISCOT, ANSELMO S, LOWELL, BRADFORD B, BICUDO, JOSE EDUARDO P. W, BIANCO, ANTONIO C

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Transcriptional co-activator PGC-1α drives the formation of slow-twitch muscle fibres von Spiegelman, Bruce M, Lin, Jiandie, Wu, Hai, Tarr, Paul T, Zhang, Chen-Yu, Wu, Zhidan, Boss, Olivier, Michael, Laura F, Puigserver, Pere, Isotani, Eiji, Olson, Eric N, Lowell, Bradford B, Bassel-Duby, Rhonda

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Uncoupling proteins 2 and 3: potential regulators of mitochondrial energy metabolism von BOSS, O, HAGEN, T, LOWELL, B. B

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