Cost-effectiveness of High-performance Biomarker Tests vs Fecal Immunochemical Test for Noninvasive Colorectal Cancer Screening von Lansdorp-Vogelaar, Iris, Goede, S. Lucas, Bosch, Linda J.W., Melotte, Veerle, Carvalho, Beatriz, van Engeland, Manon, Meijer, Gerrit A., de Koning, Harry J., van Ballegooijen, Marjolein

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Molecular Tests for Colorectal Cancer Screening von Bosch, Linda J.W, Carvalho, Beatriz, Fijneman, Remond J.A, Jimenez, Connie R, Pinedo, Herbert M, van Engeland, Manon, Meijer, Gerrit A

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Promoter CpG island hypermethylation- and H3K9me3 and H3K27me3-mediated epigenetic silencing targets the deleted in colon cancer (DCC) gene in colorectal carcinogenesis without aff... von Derks, Sarah, Bosch, Linda J.W., Niessen, Hanneke E.C., Moerkerk, Peter T.M., van den Bosch, Sandra M., Carvalho, Beatriz, Mongera, Sandra, Voncken, J.Willem, Meijer, Gerrit A., de Bruïne, Adriaan P., Herman, James G., van Engeland, Manon

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DNA methylation of phosphatase and actin regulator 3 detects colorectal cancer in stool and complements FIT von Bosch, Linda J W, Oort, Frank A, Neerincx, Maarten, Khalid-de Bakker, Carolina A J, Terhaar sive Droste, Jochim S, Melotte, Veerle, Jonkers, Daisy M A E, Masclee, Ad A M, Mongera, Sandra, Grooteclaes, Madeleine, Louwagie, Joost, van Criekinge, Wim, Coupé, Veerle M H, Mulder, Chris J, van Engeland, Manon, Carvalho, Beatriz, Meijer, Gerrit A

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IFN-γ signature enables selection of neoadjuvant treatment in patients with stage III melanoma von Reijers, Irene L M, Rao, Disha, Versluis, Judith M, Menzies, Alexander M, Dimitriadis, Petros, Wouters, Michel W, Spillane, Andrew J, Klop, Willem M C, Broeks, Annegien, Bosch, Linda J W, Lopez-Yurda, Marta, van Houdt, Winan J, Rawson, Robert V, Grijpink-Ongering, Lindsay G, Gonzalez, Maria, Cornelissen, Sten, Bouwman, Jasper, Sanders, Joyce, Plasmeijer, Elsemieke, Elshot, Yannick S, Scolyer, Richard A, van de Wiel, Bart A, Peeper, Daniel S, van Akkooi, Alexander C J, Long, Georgina V, Blank, Christian U

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Identification of the optimal combination dosing schedule of neoadjuvant ipilimumab plus nivolumab in macroscopic stage III melanoma (OpACIN-neo): a multicentre, phase 2, randomise... von Rozeman, Elisa A, Menzies, Alexander M, van Akkooi, Alexander C J, Adhikari, Chandra, Bierman, Carolien, van de Wiel, Bart A, Scolyer, Richard A, Krijgsman, Oscar, Sikorska, Karolina, Eriksson, Hanna, Broeks, Annegien, van Thienen, Johannes V, Guminski, Alexander D, Acosta, Alex Torres, ter Meulen, Sylvia, Koenen, Anne Miek, Bosch, Linda J W, Shannon, Kerwin, Pronk, Loes M, Gonzalez, Maria, Ch'ng, Sydney, Grijpink-Ongering, Lindsay G, Stretch, Jonathan, Heijmink, Stijn, van Tinteren, Harm, Haanen, John B A G, Nieweg, Omgo E, Klop, Willem M C, Zuur, Charlotte L, Saw, Robyn P M, van Houdt, Winan J, Peeper, Daniel S, Spillane, Andrew J, Hansson, Johan, Schumacher, Ton N, Long, Georgina V, Blank, Christian U

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Proteins in stool as biomarkers for non‐invasive detection of colorectal adenomas with high risk of progression von Komor, Malgorzata A, Bosch, Linda JW, Coupé, Veerle MH, Rausch, Christian, Pham, Thang V, Piersma, Sander R, Mongera, Sandra, Mulder, Chris JJ, Dekker, Evelien, Kuipers, Ernst J, Wiel, Mark A, Carvalho, Beatriz, Fijneman, Remond JA, Jimenez, Connie R, Meijer, Gerrit A, Wit, Meike

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Feasibility of whole‐genome sequencing‐based tumor diagnostics in routine pathology practice von Samsom, Kris G, Schipper, Luuk J, Roepman, Paul, Bosch, Linda JW, Lalezari, Ferry, Klompenhouwer, Elisabeth G, Langen, Adrianus J, Buffart, Tineke E, Riethorst, Immy, Schoenmaker, Lieke, Schout, Daoin, Noort, Vincent, Berg, Jose G, Bruijn, Ewart, Hoeven, Jacobus JM, Snellenberg, Hans, Kolk, Lizet E, Cuppen, Edwin, Voest, Emile E, Meijer, Gerrit A, Monkhorst, Kim

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Transcriptomic profiling of adjuvant colorectal cancer identifies three key prognostic biological processes and a disease specific role for granzyme B von Daemen, Anneleen, Udyavar, Akshata R, Sandmann, Thomas, Li, Congfen, Bosch, Linda J W, O'Gorman, William, Li, Yijin, Au-Yeung, Amelia, Takahashi, Chikara, Kabbarah, Omar, Bourgon, Richard, Hegde, Priti, Bais, Carlos, Das Thakur, Meghna

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A phase 2 trial combining afatinib with cetuximab in patients with EGFR exon 20 insertion–positive non–small cell lung cancer von Veggel, Bianca A. M. H., Wekken, Anthonie J., Paats, Marthe S., Hendriks, Lizza E. L., Hashemi, Sayed M. S., Daletzakis, Antonios, Broek, Daan, Bosch, Linda J. W., Monkhorst, Kim, Smit, Egbert F., Langen, Adrianus J.

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Consensus molecular subtype classification of colorectal adenomas von Komor, Malgorzata A, Bosch, Linda JW, Bounova, Gergana, Bolijn, Anne S, Delis‐van Diemen, Pien M, Rausch, Christian, Hoogstrate, Youri, Stubbs, Andrew P, de Jong, Mark, Jenster, Guido, van Grieken, Nicole CT, Carvalho, Beatriz, Wessels, Lodewyk FA, Jimenez, Connie R, Fijneman, Remond JA, Meijer, Gerrit A, Dits, Natasja, Bottcher, Rene, Hiemstra, Annemieke C, Ylstra, Bauke, Sie, Daoud, van den Broek, Evert, van der Meer, David, Pepers, Floor, Caldenhoven, Eric, Janssen, Bart, van Workum, Wilbert, van Lieshout, Stef, Bangma, Chris H., van Leenders, Geert, van de Werken, Harmen

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Aurora kinase A (AURKA) interaction with Wnt and Ras-MAPK signalling pathways in colorectal cancer von Jacobsen, Annika, Bosch, Linda J. W., Martens-de Kemp, Sanne R., Carvalho, Beatriz, Sillars-Hardebol, Anke H., Dobson, Richard J., de Rinaldis, Emanuele, Meijer, Gerrit A., Abeln, Sanne, Heringa, Jaap, Fijneman, Remond J. A., Feenstra, K. Anton

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Optimized whole-genome sequencing workflow for tumor diagnostics in routine pathology practice von Samsom, Kris G., Bosch, Linda J. W., Schipper, Luuk J., Schout, Daoin, Roepman, Paul, Boelens, Mirjam C., Lalezari, Ferry, Klompenhouwer, Elisabeth G., de Langen, Adrianus J., Buffart, Tineke E., van Linder, Berit M. H., van Deventer, Kelly, van den Burg, Kay, Unmehopa, Unga, Rosenberg, Efraim H., Koster, Roelof, Hogervorst, Frans B. L., van den Berg, José G., Riethorst, Immy, Schoenmaker, Lieke, van Beek, Daphne, de Bruijn, Ewart, van der Hoeven, Jacobus J. M., van Snellenberg, Hans, van der Kolk, Lizet E., Cuppen, Edwin, Voest, Emile E., Meijer, Gerrit A., Monkhorst, Kim

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Costs, throughput time, and proportion of valid test results, a model-based analysis of liquid biopsies for stage IV non-small cell lung cancer von Koole, Simone N., Schouten, Robert, Vessies, Daan, Schuurbiers, Milou, Bosch, Linda J.W., van den Heuvel, Michel, van Harten, Wim, van den Broek, Daan, Monkhorst, Kim, Retel, Valesca P.

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Impact of genetic counseling strategy on diagnostic yield and workload for genome-sequencing-based tumor diagnostics von Koster, Roelof, Schipper, Luuk J., Giesbertz, Noor A.A., van Beek, Daphne, Mendeville, Matías, Samsom, Kris G., Rosenberg, Efraim H., Hogervorst, Frans B.L., Roepman, Paul, Boelens, Mirjam C., Bosch, Linda J.W., van den Berg, Jose G., Meijer, Gerrit A., Voest, Emile E., Cuppen, Edwin, Ruijs, Marielle W.G., van Wezel, Tom, van der Kolk, Lizet, Monkhorst, Kim

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The interferon-gamma (IFN-y) signature from baseline tumor material predicts pathologic response after neoadjuvant ipilimumab (IPI) + nivolumab (NIVO) in stage III melanoma von Reijers, Irene L.M., Dimitriadis, Petros, Rozeman, Elisa A., Krijgsman, Oscar, Cornelissen, Sten, Bosch, Linda J.W., Broeks, Annegien, Menzies, Alexander M., van de Wiel, Bart A., Scolyer, Richard A., Long, Georgina V., Blank, Christian U.

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Study protocol: Whole genome sequencing Implementation in standard Diagnostics for Every cancer patient (WIDE) von Samsom, Kris G, Bosch, Linda J W, Schipper, Luuk J, Roepman, Paul, de Bruijn, Ewart, Hoes, Louisa R, Riethorst, Immy, Schoenmaker, Lieke, van der Kolk, Lizet E, Retèl, Valesca P, Frederix, Geert W J, Buffart, Tineke E, van der Hoeven, Jacobus J M, Voest, Emile E, Cuppen, Edwin, Monkhorst, Kim, Meijer, Gerrit A

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Whole-genome sequencing to improve sarcoma diagnosis and patient care von Schipper, Luuk J., Monkhorst, Kim, Samsom, Kris, Snaebjornsson, Petur, Van Boven, Hester, Roepman, Paul, Van Der Kolk, Lizet, Bosch, Linda J.W., van Houdt, Winan J., Van Der Graaf, Winette T.A., Meijer, Gerrit A., Voest, Emile E.

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Feasibility of whole-genome sequencing in routine clinical practice von Samsom, Kris, Monkhorst, Kim, Schipper, Luuk J., Roepman, Paul, Bosch, Linda J.W., de Bruijn, Ewart, Riethorst, Immy, Schoenmaker, Lieke, Van Der Kolk, Lizet, Buffart, Tineke, van der Hoeven, Jacobus J.M., Cuppen, Edwin P.J.G., Voest, Emile E., Meijer, Gerrit A.

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Clinical Impact of Prospective Whole Genome Sequencing in Sarcoma Patients von Schipper, Luuk J, Monkhorst, Kim, Samsom, Kris G, Bosch, Linda J W, Snaebjornsson, Petur, van Boven, Hester, Roepman, Paul, van der Kolk, Lizet E, van Houdt, Winan J, van der Graaf, Winette T A, Meijer, Gerrit A, Voest, Emile E

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