Diverse BRCA1 and BRCA2 Reversion Mutations in Circulating Cell-Free DNA of Therapy-Resistant Breast or Ovarian Cancer von Weigelt, Britta, Comino-Méndez, Iñaki, de Bruijn, Ino, Tian, Lei, Meisel, Jane L, García-Murillas, Isaac, Fribbens, Charlotte, Cutts, Ros, Martelotto, Luciano G, Ng, Charlotte K Y, Lim, Raymond S, Selenica, Pier, Piscuoglio, Salvatore, Aghajanian, Carol, Norton, Larry, Murali, Rajmohan, Hyman, David M, Borsu, Laetitia, Arcila, Maria E, Konner, Jason, Reis-Filho, Jorge S, Greenberg, Roger A, Robson, Mark E, Turner, Nicholas C

Volltext

A Prospective Study of Circulating Tumor DNA to Guide Matched Targeted Therapy in Lung Cancers von Sabari, Joshua K, Offin, Michael, Stephens, Dennis, Ni, Andy, Lee, Adrian, Pavlakis, Nick, Clarke, Stephen, Diakos, Connie I, Datta, Sutirtha, Tandon, Nidhi, Martinez, Andres, Myers, Mackenzie L, Makhnin, Alex, Leger, Ysleni, Yu, Helena A, Paik, Paul K, Chaft, Jamie E, Kris, Mark G, Jeon, Jeong O, Borsu, Laetitia A, Ladanyi, Marc, Arcila, Maria E, Hernandez, Jennifer, Henderson, Samantha, Shaffer, Tristan, Garg, Kavita, DiPasquo, Dan, Raymond, Christopher K, Lim, Lee P, Li, Mark, Hellmann, Matthew D, Drilon, Alexander, Riely, Gregory J, Rusch, Valerie W, Jones, David R, Rimner, Andreas, Rudin, Charles M, Isbell, James M, Li, Bob T

Volltext

Comprehensive Molecular and Clinicopathologic Analysis of 200 Pulmonary Invasive Mucinous Adenocarcinomas Identifies Distinct Characteristics of Molecular Subtypes von Chang, Jason C, Offin, Michael, Falcon, Christina, Brown, David, Houck-Loomis, Brian R, Meng, Fanli, Rudneva, Vasilisa A, Won, Helen H, Amir, Sharon, Montecalvo, Joseph, Desmeules, Patrice, Kadota, Kyuichi, Adusumilli, Prasad S, Rusch, Valerie W, Teed, Sarah, Sabari, Joshua K, Benayed, Ryma, Nafa, Khedoudja, Borsu, Laetitia, Li, Bob T, Schram, Alison M, Arcila, Maria E, Travis, William D, Ladanyi, Marc, Drilon, Alexander, Rekhtman, Natasha

Volltext

Expanding the Molecular Characterization of Thoracic Inflammatory Myofibroblastic Tumors beyond ALK Gene Rearrangements von Chang, Jason C., Zhang, Lei, Drilon, Alexander E., Chi, Ping, Alaggio, Rita, Borsu, Laetitia, Benayed, Ryma, Travis, William D., Ladanyi, Marc, Antonescu, Cristina R.

Volltext

Alternative transcription initiation leads to expression of a novel ALK isoform in cancer von Wiesner, Thomas, Lee, William, Obenauf, Anna C., Ran, Leili, Murali, Rajmohan, Zhang, Qi Fan, Wong, Elissa W. P., Hu, Wenhuo, Scott, Sasinya N., Shah, Ronak H., Landa, Iñigo, Button, Julia, Lailler, Nathalie, Sboner, Andrea, Gao, Dong, Murphy, Devan A., Cao, Zhen, Shukla, Shipra, Hollmann, Travis J., Wang, Lu, Borsu, Laetitia, Merghoub, Taha, Schwartz, Gary K., Postow, Michael A., Ariyan, Charlotte E., Fagin, James A., Zheng, Deyou, Ladanyi, Marc, Busam, Klaus J., Berger, Michael F., Chen, Yu, Chi, Ping

Volltext

Histone Deacetylases Are Required for Androgen Receptor Function in Hormone-Sensitive and Castrate-Resistant Prostate Cancer von WELSBIE, Derek S, JIN XU, YU CHEN, BORSU, Laetitia, SCHER, Howard I, ROSEN, Neal, SAWYERS, Charles L

Volltext

Detection of an NRAS mutation in Erdheim-Chester disease von Diamond, Eli L., Abdel-Wahab, Omar, Pentsova, Elena, Borsu, Laetitia, Chiu, April, Teruya-Feldstein, Julie, Hyman, David M., Rosenblum, Marc

Volltext

Novel oncogene and tumor suppressor mutations in KIT and PDGFRA wild type gastrointestinal stromal tumors revealed by next generation sequencing von Hechtman, Jaclyn Frances, Zehir, Ahmet, Mitchell, Talia, Borsu, Laetitia, Singer, Samuel, Tap, William, Oultache, Alifya, Ladanyi, Marc, Nafa, Khedoudja

Volltext

Genetic variation in DNA repair pathways and risk of non-Hodgkin's lymphoma von Rendleman, Justin, Antipin, Yevgeniy, Reva, Boris, Adaniel, Christina, Przybylo, Jennifer A, Dutra-Clarke, Ana, Hansen, Nichole, Heguy, Adriana, Huberman, Kety, Borsu, Laetitia, Paltiel, Ora, Ben-Yehuda, Dina, Brown, Jennifer R, Freedman, Arnold S, Sander, Chris, Zelenetz, Andrew, Klein, Robert J, Shao, Yongzhao, Lacher, Mortimer, Vijai, Joseph, Offit, Kenneth, Kirchhoff, Tomas

Volltext

Sequencing of 279 cancer genes in ampullary carcinoma reveals trends relating to histologic subtypes and frequent amplification and overexpression of ERBB2 (HER2) von Hechtman, Jaclyn F, Liu, Weiguo, Sadowska, Justyna, Zhen, Lisa, Borsu, Laetitia, Arcila, Maria E, Won, Helen H, Shah, Ronak H, Berger, Michael F, Vakiani, Efsevia, Shia, Jinru, Klimstra, David S

Volltext

Unsuspected Collision of Synchronous Lung Adenocarcinomas: A Potential Cause of Aberrant Driver Mutation Profiles von Rekhtman, Natasha, Borsu, Laetitia, Reva, Boris, Arcila, Maria, Riely, Gregory J., Ladanyi, Marc, Drilon, Alexander

Volltext

Response to MET inhibitors in patients with stage IV lung adenocarcinomas harboring MET mutations causing exon 14 skipping von Paik, Paul K, Drilon, Alexander, Fan, Pang-Dian, Yu, Helena, Rekhtman, Natasha, Ginsberg, Michelle S, Borsu, Laetitia, Schultz, Nikolaus, Berger, Michael F, Rudin, Charles M, Ladanyi, Marc

Volltext

Memorial Sloan Kettering-Integrated Mutation Profiling of Actionable Cancer Targets (MSK-IMPACT): A Hybridization Capture-Based Next-Generation Sequencing Clinical Assay for Solid... von Cheng, Donavan T, Mitchell, Talia N, Zehir, Ahmet, Shah, Ronak H, Benayed, Ryma, Syed, Aijazuddin, Chandramohan, Raghu, Liu, Zhen Yu, Won, Helen H, Scott, Sasinya N, Brannon, A Rose, O'Reilly, Catherine, Sadowska, Justyna, Casanova, Jacklyn, Yannes, Angela, Hechtman, Jaclyn F, Yao, Jinjuan, Song, Wei, Ross, Dara S, Oultache, Alifya, Dogan, Snjezana, Borsu, Laetitia, Hameed, Meera, Nafa, Khedoudja, Arcila, Maria E, Ladanyi, Marc, Berger, Michael F

Volltext

Memorial Sloan Kettering-Integrated Mutation Profiling of Actionable Cancer Targets (MSK-IMPACT) von Cheng, Donavan T, Mitchell, Talia N, Zehir, Ahmet, Shah, Ronak H, Benayed, Ryma, Syed, Aijazuddin, Chandramohan, Raghu, Liu, Zhen Yu, Won, Helen H, Scott, Sasinya N, Brannon, A. Rose, O'Reilly, Catherine, Sadowska, Justyna, Casanova, Jacklyn, Yannes, Angela, Hechtman, Jaclyn F, Yao, Jinjuan, Song, Wei, Ross, Dara S, Oultache, Alifya, Dogan, Snjezana, Borsu, Laetitia, Hameed, Meera, Nafa, Khedoudja, Arcila, Maria E, Ladanyi, Marc, Berger, Michael F

Volltext

RAS mutations affect pattern of metastatic spread and increase propensity for brain metastasis in colorectal cancer von Yaeger, Rona, Cowell, Elizabeth, Chou, Joanne F., Gewirtz, Alexandra N., Borsu, Laetitia, Vakiani, Efsevia, Solit, David B., Rosen, Neal, Capanu, Marinela, Ladanyi, Marc, Kemeny, Nancy

Volltext

The Somatic Genomic Landscape of Glioblastoma von Brennan, Cameron W., Noushmehr, Houtan, Salama, Sofie R., Berman, Samuel H., Beroukhim, Rameen, Wu, Chang-Jiun, Yung, W.K., Sougnez, Carrie, Finocchiaro, Gaetano, O’Neill, Brian P., Myers, Jerome, Weisenberger, Daniel J., Penny, Robert, Marra, Marco, Meyerson, Matthew, Chin, Lynda, Ostrom, Quinn, Wolinsky, Yingli, Black, Keith L., Boulos, Madgy, Brown, Jenn, Czerinski, Christine, Koyfman, Yakov, Rabeno, Brenda, Auman, J.Todd, Lee, Semin, Kalkanis, Steven, Mikkelsen, Tom, Scarpace, Lisa, Reynolds, Sheila, Curley, Erin, Morris, Scott, Yena, Peggy, Cuppini, Lucia, Maderna, Emanuela, Pollo, Bianca, Hoadley, Katherine A., Shi, Yan, Topal, Michael D., Aksoy, B. Arman, Antipin, Yevgeniy, Borsu, Laetitia, Brennan, Cameron W., Gao, Jianjiong, Jacobsen, Anders, Ladanyi, Marc, Lash, Alex, Liang, Yupu, Chen, Qing-Rong, Shaw, Kenna R. Mills, Eckman, John, Eley, Greg, Jensen, Mark A., Kahn, Ari, Pot, David A., Wan, Yunhu, Hansen, Nathan, Hothi, Parvi, Lau, Ching, Cherniack, Andrew D., Noble, Mike, Cibulskis, Kristian, Frazer, Scott, Gabriel, Stacey B., Gehlenborg, Nils, Gentry, Jeff, Heiman, David, Lander, Eric S., Mallard, Will, Meyerson, Matthew, Getz, Gad, Dees, Nathan N., Fulton, Robert S., Kanchi, Krishna-Latha, Devine, Karen, Carlin, Daniel, Ellrott, Kyle, Haussler, David, Ng, Sam, Salama, Sofie R., Waltman, Peter, Zhu, Jing, Frentzen, Barbara, Friedman, William, McTiernan, Raquel, Perou, Charles M., Akbani, Rehan, Aldape, Kenneth, Bogler, Oliver, Fuller, Gregory N., Mills, Gordon, Protopopov, Alexei, Wu, Chang-Jiun, Weinstein, John N., Verhaak, Roel G.W., Noushmehr, Houtan, Triche, Timothy J., Laird, Peter W., VanMeir, Erwin G., Brat, Daniel

Volltext

Oncogene Mutation Profiling of Pediatric Solid Tumors Reveals Significant Subsets of Embryonal Rhabdomyosarcoma and Neuroblastoma with Mutated Genes in Growth Signaling Pathways von SHUKLA, Neerav, AMEUR, Nabahet, YILMAZ, Ismail, NAFA, Khedoudja, LAU, Chyau-Yueh, MARCHETTI, Angela, BORSU, Laetitia, BARR, Frederic G, LADANYI, Marc

Volltext

Polymorphous low-grade neuroepithelial tumor of the young (PLNTY): an epileptogenic neoplasm with oligodendroglioma-like components, aberrant CD34 expression, and genetic alteratio... von Huse, Jason T., Snuderl, Matija, Jones, David T. W., Brathwaite, Carole D., Altman, Nolan, Lavi, Ehud, Saffery, Richard, Sexton-Oates, Alexandra, Blumcke, Ingmar, Capper, David, Karajannis, Matthias A., Benayed, Ryma, Chavez, Lukas, Thomas, Cheddhi, Serrano, Jonathan, Borsu, Laetitia, Ladanyi, Marc, Rosenblum, Marc K.

Volltext

Comprehensive genomic characterization of squamous cell lung cancers

Volltext

MAP2K1 (MEK1) Mutations Define a Distinct Subset of Lung Adenocarcinoma Associated with Smoking von Arcila, Maria E, Drilon, Alexander, Sylvester, Brooke E, Lovly, Christine M, Borsu, Laetitia, Reva, Boris, Kris, Mark G, Solit, David B, Ladanyi, Marc

Volltext