Antimetastatic and antiangiogenic activity of trabectedin in cutaneous melanoma von Carminati, Laura, Pinessi, Denise, Borsotti, Patrizia, Minoli, Lucia, Giavazzi, Raffaella, D’Incalci, Maurizio, Belotti, Dorina, Taraboletti, Giulia

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Shedding of the Matrix Metalloproteinases MMP-2, MMP-9, and MT1-MMP as Membrane Vesicle-Associated Components by Endothelial Cells von Taraboletti, Giulia, D'Ascenzo, Sandra, Borsotti, Patrizia, Giavazzi, Raffaella, Pavan, Antonio, Dolo, Vincenza

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Fibronectin fragments generated by pancreatic trypsin act as endogenous inhibitors of pancreatic tumor growth von Resovi, Andrea, Persichitti, Perla, Brunelli, Laura, Minoli, Lucia, Borsotti, Patrizia, Garattini, Giulia, Tironi, Matteo, Dugnani, Erica, Redegalli, Miriam, De Simone, Giulia, Pastorelli, Roberta, Bani, Maria Rosa, Piemonti, Lorenzo, Mosher, Deane F, Giavazzi, Raffaella, Taraboletti, Giulia, Belotti, Dorina

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CCN-Based Therapeutic Peptides Modify Pancreatic Ductal Adenocarcinoma Microenvironment and Decrease Tumor Growth in Combination with Chemotherapy von Resovi, Andrea, Borsotti, Patrizia, Ceruti, Tommaso, Passoni, Alice, Zucchetti, Massimo, Berndt, Alexander, Riser, Bruce L., Taraboletti, Giulia, Belotti, Dorina

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Bioavailability of VEGF in Tumor-Shed Vesicles Depends on Vesicle Burst Induced by Acidic pH von Taraboletti, Giulia, D'Ascenzoy, Sandra, Giusti, Ilaria, Marchetti, Daniela, Borsotti, Patrizia, Millimaggi, Danilo, Giavazzi, Raffaella, Pavan, Antonio, Dolo, Vincenza

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Endothelin-1 Induces an Angiogenic Phenotype in Cultured Endothelial Cells and Stimulates Neovascularization In Vivo von Salani, Debora, Taraboletti, Giulia, Rosanò, Laura, Di Castro, Valeriana, Borsotti, Patrizia, Giavazzi, Raffaella, Bagnato, Anna

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Inhibition of SIRT2 Potentiates the Anti-motility Activity of Taxanes: Implications for Antineoplastic Combination Therapies von Bonezzi, Katiuscia, Belotti, Dorina, North, Brian J, Ghilardi, Carmen, Borsotti, Patrizia, Resovi, Andrea, Ubezio, Paolo, Riva, Antonella, Giavazzi, Raffaella, Verdin, Eric, Taraboletti, Giulia

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The Vascular Targeting Property of Paclitaxel Is Enhanced by SU6668, a Receptor Tyrosine Kinase Inhibitor, Causing Apoptosis of Endothelial Cells and Inhibition of Angiogenesis von NAUMOVA, Elitza, UBEZIO, Paolo, GAROFALO, Angela, BORSOTTI, Patrizia, CASSIS, Linda, RICCARDI, Elena, SCANZIANI, Eugenio, ECCLES, Suzanne A, BANI, Maria R, GIAVAZZI, Raffaella

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BAY 12-9566, A Novel Inhibitor of Matrix Metalloproteinases with Antiangiogenic Activity von GATTO, C, RIEPPI, M, BORSOTTI, P, INNOCENTI, S, CERUTI, R, DRUDIS, T, SCANZIANI, E, CASAZZA, A. M, TARABOLETTI, G, GIAVAZZI, R

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Potential Antagonism of Tubulin-Binding Anticancer Agents in Combination Therapies von TARABOLETTI, Giulia, MICHELETTI, Gianluca, DOSSI, Romina, BORSOTTI, Patrizia, MARTINELLI, Michele, FIORDALISO, Fabio, RYAN, Anderson J, GIAVAZZI, Raffaella

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Antiangiogenic and Antitumor Activity of IDN 5390, a New Taxane Derivative von TARABOLETTI, Giulia, MICHELETTI, Gianluca, BOMBARDELLI, Ezio, MORAZZONI, Paolo, RIVA, Antonella, GIAVAZZI, Raffaella, RIEPPI, Monica, POLI, Maura, TURATTO, Michele, ROSSI, Cosmo, BORSOTTI, Patrizia, ROCCABIANCA, Paola, SCANZIANI, Eugenio, NICOLETTI, Maria Ines

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Abstract 198: The T3R domain of thrombospondin-1 delays tumor growth and improves tumor response to chemotherapy by remodeling the tumor vasculature von Pinessi, Denise, Resovi, Andrea, Morosi, Lavinia, Borsotti, Patrizia, Berndt, Alexander, Giavazzi, Raffaella, Zucchetti, Massimo, Taraboletti, Giulia

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p73 overexpression increases VEGF and reduces thrombospondin-1 production: implications for tumor angiogenesis von VIKHANSKAYA, Faina, BANI, Maria R, BORSOTTI, Patrizia, GHILARDI, Carmen, CERUTI, Roberta, GHISLENI, Gabricle, MARABESE, Mirko, GIAVAZZI, Raffaella, BROGGINI, Massimo, TARABOLETTI, Giulia

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Abstract 916: A novel LAP-IL2 fusion protein elicits efficacy as single agent in syngeneic renal and melanoma mouse models von Riveiro, Maria Eugenia, Frapolli, Roberta, Taraboletti, Giulia Taraboletti Giulia, Rezai, Keyvan, Meroni, Marina, Russo, Massimo, Borsotti, Patrizia, Schultz, Chris, Gould, David, Chernajovsky, Yuti

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Vascular Disrupting Activity of Tubulin-Binding 1,5-Diaryl-1H-imidazoles von Bonezzi, Katiuscia, Taraboletti, Giulia, Borsotti, Patrizia, Bellina, Fabio, Rossi, Renzo, Giavazzi, Raffaella

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The calcium-binding type III repeats domain of thrombospondin-2 binds to fibroblast growth factor 2 (FGF2) von Rusnati, Marco, Borsotti, Patrizia, Moroni, Elisabetta, Foglieni, Chiara, Chiodelli, Paola, Carminati, Laura, Pinessi, Denise, Annis, Douglas S., Paiardi, Giulia, Bugatti, Antonella, Gori, Alessandro, Longhi, Renato, Belotti, Dorina, Mosher, Deane F., Colombo, Giorgio, Taraboletti, Giulia

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Antiangiogenic activity of trabectedin in myxoid liposarcoma: Involvement of host TIMP‐1 and TIMP‐2 and tumor thrombospondin‐1 von Dossi, Romina, Frapolli, Roberta, Di Giandomenico, Silvana, Paracchini, Lara, Bozzi, Fabio, Brich, Silvia, Castiglioni, Vittoria, Borsotti, Patrizia, Belotti, Dorina, Uboldi, Sarah, Sanfilippo, Roberta, Erba, Eugenio, Giavazzi, Raffaella, Marchini, Sergio, Pilotti, Silvana, D'Incalci, Maurizio, Taraboletti, Giulia

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Tumor vascular remodeling by thrombospondin-1 enhances drug delivery and antineoplastic activity von Pinessi, Denise, Resovi, Andrea, Sangalli, Fabio, Morosi, Lavinia, Zentilin, Lorena, Borsotti, Patrizia, Carlessi, Elena, Passoni, Alice, Davoli, Enrico, Belotti, Dorina, Giavazzi, Raffaella, Giacca, Mauro, Valbusa, Giovanni, Berndt, Alexander, Zucchetti, Massimo, Taraboletti, Giulia

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Thrombospondin-1 is part of a Slug-independent motility and metastatic program in cutaneous melanoma, in association with VEGFR-1 and FGF-2 von Borsotti, Patrizia, Ghilardi, Carmen, Ostano, Paola, Silini, Antonietta, Dossi, Romina, Pinessi, Denise, Foglieni, Chiara, Scatolini, Maria, Lacal, Pedro M., Ferrari, Raffaele, Moscatelli, Davide, Sangalli, Fabio, D'Atri, Stefania, Giavazzi, Raffaella, Bani, Maria Rosa, Chiorino, Giovanna, Taraboletti, Giulia

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Thrombospondin-1 inhibits Kaposi's sarcoma (KS) cell and HIV-1 Tat-induced angiogenesis and is poorly expressed in KS lesions von Taraboletti, Giulia, Benelli, Roberto, Borsotti, Patrizia, Rusnati, Marco, Presta, Marco, Giavazzi, Raffaella, Ruco, Luigi, Albini, Adriana

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