Concurrent SOS1 and MEK suppression inhibits signaling and growth of NF1-null melanoma von Marasco, Michelangelo, Kumar, Dinesh, Seale, Tessa, Borrego, Santiago Garcia, Kaplun, Esther, Aricescu, Ilinca, Cole, Soren, Qeriqi, Besnik, Qiu, Juan, Chen, Xiaoping, Bahr, Amber, Fidele, Deborah, Hofmann, Marco H., Gerlach, Daniel, Savarese, Fabio, Merghoub, Taha, Wolchok, Jedd D., Yao, Zhan, de Stanchina, Elisa, Solit, David, Misale, Sandra, Rosen, Neal

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Chemotherapy de-escalation using an F-18-FDG-PET-based pathological response-adapted strategy in patients with HER2-positive early breast cancer (PHERGain): a multicentre, randomis... von Manuel Perez-Garcia, Jose, Gebhart, Geraldine, Ruiz Borrego, Manuel, Stradella, Agostina, Bermejo, Begona, Schmid, Peter, Marme, Frederik, Escriva-de-Romani, Santiago, Calvo, Lourdes, Ribelles, Nuria, Martinez, Noelia, Albacar, Cinta, Prat, Aleix, Dalenc, Florence, Kerrou, Khaldoun, Colleoni, Marco, Afonso, Noemia, Di Cosimo, Serena, Sampayo-Cordero, Miguel, Malfettone, Andrea, Cortes, Javier, Llombart-Cussac, Antonio

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Eculizumab in secondary atypical haemolytic uraemic syndrome von Cavero, Teresa, Rabasco, Cristina, López, Antía, Román, Elena, Ávila, Ana, Sevillano, Ángel, Huerta, Ana, Rojas-Rivera, Jorge, Fuentes, Carolina, Blasco, Miquel, Jarque, Ana, García, Alba, Mendizabal, Santiago, Gavela, Eva, Macía, Manuel, Quintana, Luis F, María Romera, Ana, Borrego, Josefa, Arjona, Emi, Espinosa, Mario, Portolés, José, Gracia-Iguacel, Carolina, González-Parra, Emilio, Aljama, Pedro, Morales, Enrique, Cao, Mercedes, Rodríguez de Córdoba, Santiago, Praga, Manuel

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Vulvovaginal atrophy in the CRETA study: the healthcare professionals' perception von Cancelo, María J, Sánchez Borrego, Rafael, Palacios, Santiago, Baquedano, Laura, Corbacho Garza, Tanit, Fernández Aller, Noelia, García Ferreiro, Carmen, Quijano Martín, Juan José, González Calvo, A Javier

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3-year invasive disease-free survival with chemotherapy de-escalation using an 18F-FDG-PET-based, pathological complete response-adapted strategy in HER2-positive early breast canc... von Pérez-García, José Manuel, Cortés, Javier, Ruiz-Borrego, Manuel, Colleoni, Marco, Stradella, Agostina, Bermejo, Begoña, Dalenc, Florence, Escrivá-de-Romaní, Santiago, Calvo Martínez, Lourdes, Ribelles, Nuria, Marmé, Frederik, Cortés, Alfonso, Albacar, Cinta, Gebhart, Geraldine, Prat, Aleix, Kerrou, Khaldoun, Schmid, Peter, Braga, Sofia, Di Cosimo, Serena, Gion, Maria, Antonarelli, Gabriele, Popa, Crina, Szostak, Emilia, Alcalá-López, Daniel, Gener, Petra, Rodríguez-Morató, Jose, Mina, Leonardo, Sampayo-Cordero, Miguel, Llombart-Cussac, Antonio

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Impact of SARS-CoV-2 infection in patients with cystic fibrosis in Spain: Incidence and results of the national CF-COVID19-Spain survey von Mondejar-Lopez, Pedro, Quintana-Gallego, Esther, Giron-Moreno, Rosa M., Cortell-Aznar, Isidoro, Ruiz de Valbuena-Maiz, Marta, Diab-Caceres, Layla, Prados-Sanchez, Concepcion, Alvarez-Fernandez, Antonio, Garcia-Marcos, Patricia W., Peñalver-Mellado, Carlos, Pastor-Vivero, M. Dolores, Olveira, Casilda, Lopez-Neyra, Alejandro, Castillo-Corullon, Silvia, Palma-Milla, Samara, Perez-Ruiz, Estela, Sole-Jover, Amparo, Barrio, M. Isabel, Sanchez-Solis, Manuel, Asensio de la Cruz, Óscar, Aguilar-Fernández, Antonio J., Andres-Martin, Anselmo, Blanco-Aparicio, Marina, Sirvent-Gomez, Josep, Barajas-Sanchez, Verisima, Baranda, Felix, Gomez-Bonilla, Ainhoa, Bousoño-Garcia, Carlos, Garcia-Clemente, Marta, Bover-Bauza, Catalina, Figuerola-Mulet, Joan, Cabero-Perez, M. Jesús, Iturbe-Fernandez, David, Carrasco-Hernandez, Laura, Delgado-Pecellin, Isabel, Casas-Maldonado, Francisco, Merlos-Navarro, Silvia, Valenzuela-Soria, Alfredo, Cascante-Rodrigo, J. Antonio, Moreno-Galarraga, Laura, Cols-Roig, Maria, de la Cruz, Ofelia Fernandez, Gomez de Terreros, Francisco J., Garcia-Magan, Carlos, Gartner, Silvia, Gomez-Pastrana, David, Gonzalez-Castro, Estela, Jimenez-Nogueira, Esperanza, Herrero-Labarga, M. Ines, de Vicente, Carlos Martín, Juste-Ruiz, Mercedes, Lamas-Ferreiro, Adelaida, Maiz-Carro, Luis, Luna-Paredes, M. Carmen, Mesa-Medina, Orlando, Monton-Soler, Concepcion, Ramos-Hernandez, Cristina, Rodriguez-Saez, M. Jesus, Romero-Albillos, J. Alejandro, Sanz-Santiago, Veronica, Villa-Asensi, J. Ramón, Torres-Borrego, Javier, Vaquero-Barrios, J. Manuel, Velasco-Bernardo, Rosa, Velasco-Gonzalez, Valle

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Contextualizing pertuzumab approval in the treatment of HER2-positive breast cancer patients von Cortés, Javier, Ciruelos, Eva, Pérez-García, José, Albanell, Joan, García-Estévez, Laura, Ruiz–Borrego, Manuel, Espinosa, Ruth, Gallegos, Isabel, González, Santiago, Álvarez, Isabel, Llombart, Antonio

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GECOP-MMC: phase IV randomized clinical trial to evaluate the efficacy of hyperthermic intraperitoneal chemotherapy (HIPEC) with mytomicin-C after complete surgical cytoreduction i... von Pereira, Fernando, Serrano, Angel, Manzanedo, Israel, Pérez-Viejo, Estibalitz, González-Moreno, Santiago, González-Bayón, Luis, Arjona-Sánchez, Alvaro, Torres, Juan, Ramos, Isabel, Barrios, Maria E, Cascales, Pedro, Morales, Rafael, Boldó, Enrique, García-Fadrique, Alfonso, Arteaga, Xabier, Gutierrez-Calvo, Alberto, Sánchez-García, Susana, Asensio, Enrique, Ramírez, Cesar P, Artiles, Manuel, Vaqué, Javier, Parra, Pedro A, Villarejo, Pedro, Muñoz-Casares, Cristóbal, Turienzo, Estrella, Calero, Alicia, Torrejimeno, Isabel Jaén, Prieto, Isabel, Galindo, Julio, Borrego, Vicente, Marcello, Manuel E, Rihuete, Cristina, Carrasco, Joaquin, Gomez-Quiles, Luis

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Clinicopathological and molecular predictors of [18F]FDG-PET disease detection in HER2-positive early breast cancer: RESPONSE, a substudy of the randomized PHERGain trial von Llombart-Cussac, Antonio, Prat, Aleix, Pérez-García, José Manuel, Mateos, José, Pascual, Tomás, Escrivà-de-Romani, Santiago, Stradella, Agostina, Ruiz-Borrego, Manuel, de las Heras, Begoña Bermejo, Keyaerts, Marleen, Galvan, Patricia, Brasó-Maristany, Fara, García-Mosquera, Juan José, Guiot, Thomas, Gion, María, Sampayo-Cordero, Miguel, Di Cosimo, Serena, Pérez-Escuredo, Jhudit, de Frutos, Manuel Atienza, Cortés, Javier, Gebhart, Geraldine

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Preventing alpelisib-related hyperglycaemia in HR+/HER2−/PIK3CA-mutated advanced breast cancer using metformin (METALLICA): a multicentre, open-label, single-arm, phase 2 trial von Llombart-Cussac, Antonio, Pérez-Garcia, José Manuel, Ruiz Borrego, Manuel, Tolosa, Pablo, Blanch, Salvador, Fernández-Ortega, Adela, Urruticoechea, Ander, Blancas, Isabel, Saura, Cristina, Rojas, Beatriz, Bermejo, Begoña, Ponce Lorenzo, José, Gion, María, Cortez-Castedo, Patricia, Llabres, Elisenda, Galve, Elena, Cueva, Juan Fernando, López, Ana, Alonso-Romero, José Luis, González-Santiago, Santiago, Martínez de Dueñas, Eduardo, Ciruelos, Eva, Martrat, Griselda, Gener, Petra, Alcalá-López, Daniel, Sampayo-Cordero, Miguel, Gómez-Peralta, Fernando, Cortés, Javier

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Efficacy and Safety of Intraoperative Hyperthermic Intraperitoneal Chemotherapy for Locally Advanced Colon Cancer: A Phase 3 Randomized Clinical Trial von Arjona-Sánchez, Alvaro, Espinosa-Redondo, Esther, Gutiérrez-Calvo, Alberto, Segura-Sampedro, Juan J, Pérez-Viejo, Estibalitz, Concepción-Martín, Vanessa, Sánchez-García, Susana, García-Fadrique, Alfonso, Prieto-Nieto, Isabel, Barrios-Sanchez, Pedro, Torres-Melero, Juan, Ramírez Faraco, Maria, Prada-Villaverde, Arancha, Carrasco-Campos, Joaquin, Artiles-Armas, Manuel, Villarejo-Campos, Pedro, Ortega-Pérez, Gloria, Boldo-Roda, Emrique, Sánchez-Hidalgo, Juan-Manuel, Casado-Adam, Angela, Rodríguez-Ortiz, Lidia, Aranda, Enrique, Cano-Osuna, Maria Teresa, Díaz-López, Cesar, Romero-Ruiz, Antonio, Briceño-Delgado, Javier, Rufián-Peña, Sebastian

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Health-related quality of life with palbociclib plus endocrine therapy versus capecitabine in postmenopausal patients with hormone receptor–positive metastatic breast cancer: Patie... von Kahan, Zsuzsanna, Gil-Gil, Miguel, Ruiz-Borrego, Manuel, Carrasco, Eva, Ciruelos, Eva, Muñoz, Montserrat, Bermejo, Begoña, Margeli, Mireia, Antón, Antonio, Casas, Maribel, Csöszi, Tibor, Murillo, Laura, Morales, Serafín, Calvo, Lourdes, Lang, Istvan, Alba, Emilio, de la Haba-Rodriguez, Juan, Ramos, Manuel, López, Isabel Álvarez, Gal-Yam, Einav, Garcia-Palomo, Andrés, Alvarez, Elena, González-Santiago, Santiago, Rodríguez, César A., Servitja, Sonia, Corsaro, Massimo, Rodrigálvarez, Graciela, Zielinski, Christoph, Martín, Miguel

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Original Research Health-related quality of life with palbociclib plus endocrine therapy versus capecitabine in postmenopausal patients with hormone receptor-positive metastatic br... von Kahan, Zsuzsanna, Gil-Gil, Miguel, Ruiz-Borrego, Manuel, Carrasco, Eva, Ciruelos, Eva, Munoz, Montserrat, Bermejo, Begona, Margeli, Mireia, Anton, Antonio, Casas, Maribel, Csoszi, Tibor, Murillo, Laura, Morales, Serafin, Calvo, Lourdes, Lang, Istvan, Alba, Emilio, de la Haba-Rodriguez, Juan, Ramos, Manuel, Alvarez Lopez, Isabel, Gal-Yam, Einav, Garcia-Palomo, Andres, Alvarez, Elena, Gonzalez-Santiago, Santiago, Rodriguez, Cesar A., Servitja, Sonia, Corsaro, Massimo, Rodrigalvarez, Graciela, Zielinski, Christoph, Martin, Miguel

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Clinical features of drug-induced long QT syndrome in a large prospective cohort von Campos Garcia, B, Hernandez-Ontiveros, H, Avila-Parcet, A, Garcia-Hernando, V, Carceller-Sindreu, M, Salazar-Blanco, J, Rodriguez-Santiago, B, Juanes-Borrego, A, Alonso-Martin, C, Rodriguez-Font, E, Moreno-Weidmann, Z, Mendez-Zurita, F, Vinolas-Prat, X, Guerra Ramos, J M

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Genetic characterization of drug-induced long QT syndrome in a large prospective cohort von Campos Garcia, B, Rodriguez Santiago, B, Salazar Blanco, J, Hernandez Ontiveros, H, Avila Parcet, A, Garcia Hernando, V, Carceller Sindreu, M, Juanes Borrego, A, Rodriguez Font, E, Alonso Martin, C, Mendez Zurita, F, Moreno Weidmann, Z, Vinolas Prat, X, Guerra Ramos, J M

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Screening of dementia genes by whole-exome sequencing in Spanish patients with early -onset dementia: likely pathogenic, uncertain signi ficance and risk variants von Ramos-Campoy, Oscar, Antonell, Anna, Falgas, Neus, Balasa, Mircea, Borrego-Ecija, Sergi, Rodriguez-Santiago, Benjamin, Datta, Debayan, Armengol, Lluis, Fernandez-Villullas, Guadalupe, Bosch, Beatriz, Olives, Jaume, Munoz-Garcia, Cristina, Castellvi, Magdalena, Tort-Merino, Adria, Sanchez-Valle, Raquel, Llado, Albert

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Lesion Index Titration Using Contact-Force Technology Enables Safe and Effective Radiofrequency Lesion Creation at the Root of the Aorta and Pulmonary Artery von Alfonso-Almazán, José Manuel, Quintanilla, Jorge G, García-Torrent, María Jesús, Laguna-Castro, Santiago, Rodríguez-Bobada, Cruz, González, Pablo, González-Ferrer, Juan José, Salinas, Pablo, Cañadas-Godoy, Victoria, Moreno, Javier, Borrego-Bernabé, Luis, Pérez-Castellano, Nicasio, Jalife, José, Perez-Villacastín, Julián, Filgueiras-Rama, David

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Optimal [ 18 F]FDG PET/CT Cutoff for Pathologic Complete Response in HER2-Positive Early Breast Cancer Patients Treated with Neoadjuvant Trastuzumab and Pertuzumab in the PHERGain... von Gebhart, Geraldine, Keyaerts, Marleen, Guiot, Thomas, Flamen, Patrick, Ruiz-Borrego, Manuel, Stradella, Agostina, Bermejo, Begoña, Escriva-de-Romani, Santiago, Calvo Martínez, Lourdes, Ribelles, Nuria, Fernandez-Abad, María, Albacar, Cinta, Colleoni, Marco, Garrigos, Laia, Atienza de Frutos, Manuel, Dalenc, Florence, Prat, Aleix, Marmé, Frederik, Schmid, Peter, Kerrou, Khaldoun, Braga, Sofia, Gener, Petra, Sampayo-Cordero, Miguel, Cortés, Javier, Pérez-García, José Manuel, Llombart-Cussac, Antonio

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Variability in Phelan-McDermid Syndrome in a Cohort of 210 Individuals von Nevado, Julián, García-Miñaúr, Sixto, Palomares-Bralo, María, Vallespín, Elena, Guillén-Navarro, Encarna, Rosell, Jordi, Bel-Fenellós, Cristina, Mori, María Ángeles, Milá, Montserrat, Del Campo, Miguel, Barrúz, Pilar, Santos-Simarro, Fernando, Obregón, Gabriela, Orellana, Carmen, Pachajoa, Harry, Tenorio, Jair Antonio, Galán, Enrique, Cigudosa, Juan C, Moresco, Angélica, Saleme, César, Castillo, Silvia, Gabau, Elisabeth, Pérez-Jurado, Luis, Barcia, Ana, Martín, Maria Soledad, Mansilla, Elena, Vallcorba, Isabel, García-Murillo, Pedro, Cammarata-Scalisi, Franco, Gonçalves Pereira, Natálya, Blanco-Lago, Raquel, Serrano, Mercedes, Ortigoza-Escobar, Juan Dario, Gener, Blanca, Seidel, Verónica Adriana, Tirado, Pilar, Lapunzina, Pablo

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Cumulative Genetic Score and C9orf72 Repeat Status Independently Contribute to Amyotrophic Lateral Sclerosis Risk in 2 Case-Control Studies von Dou, John, Bakulski, Kelly, Guo, Kai, Hur, Junguk, Zhao, Lili, Saez-Atienzar, Sara, Stark, Ali, Chia, Ruth, García-Redondo, Alberto, Rojas-Garcia, Ricardo, Vázquez Costa, Juan Francisco, Fernandez Santiago, Ruben, Bandres-Ciga, Sara, Gómez-Garre, Pilar, Periñán, Maria Teresa, Mir, Pablo, Pérez-Tur, Jordi, Cardona, Fernando, Menendez-Gonzalez, Manuel, Riancho, Javier, Borrego-Hernández, Daniel, Galán-Dávila, Lucia, Infante Ceberio, Jon, Pastor, Pau, Paradas, Carmen, Dols-Icardo, Oriol, Traynor, Bryan J, Feldman, Eva L, Goutman, Stephen A

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