A workflow for 3D‐CLEM investigating liver tissue von KREMER, A., VAN HAMME, E., BONNARDEL, J., BORGHGRAEF, P., GUÉRIN, C.J., GUILLIAMS, M., LIPPENS, S.

Volltext

GSK3ß, a centre-staged kinase in neuropsychiatric disorders, modulates long term memory by inhibitory phosphorylation at Serine-9 von Dewachter, I, Ris, L, Jaworski, T, Seymour, C.M, Kremer, A, Borghgraef, P, De Vijver, H, Godaux, E, Van Leuven, F

Volltext

Deregulation of NMDA-receptor function and down-stream signaling in APP[V717I] transgenic mice von Dewachter, I, Filipkowski, R.K, Priller, C, Ris, L, Neyton, J, Croes, S, Terwel, D, Gysemans, M, Devijver, H, Borghgraef, P, Godaux, E, Kaczmarek, L, Herms, J, Van Leuven, F

Volltext

Noninvasive in vivo MRI detection of neuritic plaques associated with iron in APP[V717I] transgenic mice, a model for Alzheimer's disease von Vanhoutte, G., Dewachter, I., Borghgraef, P., Van Leuven, F., Van der Linden, A.

Volltext

Synthesis of F-labelled 2-(4'-fluorophenyl)-1,3-benzothiazole and evaluation as amyloid imaging agent in comparison with [C]PIB von Serdons, K, Verduyckt, T, Vanderghinste, D, Cleynhens, J, Borghgraef, P, Vermaelen, P, Terwinghe, C, Van Leuven, F, Van Laere, K, Kung, H, Bormans, G, Verbruggen, A

Volltext

Modulation of synaptic plasticity and Tau phosphorylation by wild-type and mutant presenilin1 von Dewachter, I, Ris, L, Croes, S, Borghgraef, P, Devijver, H, Voets, T, Nilius, B, Godaux, E, Van Leuven, F

Volltext

56 Novel phospho-tau specific liposome-based vaccines to treat tau pathology von Muhs, Andreas, Theunis, C, Gafner, V, Crespo-Biel, N, Borghgraef, P, Pihlgren, M, Devijer, H, Hickman, D.T, Chuard, N, Deber, M.P. Lopez, Reis, P, Buccarello, A.L, Adolfsson, O, Pfeifer, A, van Leuven, F

Volltext

Nonsteroidal Anti-Inflammatory Drugs Repress β-Secretase Gene Promoter Activity by the Activation of PPARγ von Sastre, Magdalena, Dewachter, Ilse, Rossner, Steffen, Bogdanovic, Nenad, Rosen, Evan, Borghgraef, Peter, Evert, Bernd O., Dumitrescu-Ozimek, Lucia, Thal, Dietmar R., Landreth, Gary, Walter, Jochen, Klockgether, Thomas, van Leuven, Fred, Heneka, Michael T.

Volltext

Changed Conformation of Mutant Tau-P301L Underlies the Moribund Tauopathy, Absent in Progressive, Nonlethal Axonopathy of Tau-4R/2N Transgenic Mice von Terwel, Dick, Lasrado, Reena, Snauwaert, Johan, Vandeweert, Erno, Van Haesendonck, Chris, Borghgraef, Peter, Van Leuven, Fred

Volltext

11C-labelled PIB analogues as potential tracer agents for in vivo imaging of amyloid β in Alzheimer's disease von Serdons, K., Verduyckt, T., Vanderghinste, D., Borghgraef, P., Cleynhens, J., Van Leuven, F., Kung, H., Bormans, G., Verbruggen, A.

Volltext

Synthesis of 18F-labelled 2-(4′-fluorophenyl)-1,3-benzothiazole and evaluation as amyloid imaging agent in comparison with [ 11C]PIB von Serdons, K., Verduyckt, T., Vanderghinste, D., Cleynhens, J., Borghgraef, P., Vermaelen, P., Terwinghe, C., Leuven, F. Van, Laere, K. Van, Kung, H., Bormans, G., Verbruggen, A.

Volltext

Transgenic mouse models for Alzheimer's disease: the role of GSK-3β in combined amyloid and tau-pathology von Muyllaert, D., Terwel, D., Borghgraef, P., Devijver, H., Dewachter, I., Van Leuven, F.

Volltext

Improved Long-Term Potentiation and Memory in Young Tau-P301L Transgenic Mice before Onset of Hyperphosphorylation and Tauopathy von Boekhoorn, Karin, Terwel, Dick, Biemans, Barbara, Borghgraef, Peter, Wiegert, Olof, Ramakers, Ger J. A, de Vos, Koos, Krugers, Harm, Tomiyama, Takami, Mori, Hiroshi, Joels, Marian, van Leuven, Fred, Lucassen, Paul J

Volltext

Glycogen synthase kinase‐3β, or a link between amyloid and tau pathology? von Muyllaert, D., Kremer, A., Jaworski, T., Borghgraef, P., Devijver, H., Croes, S., Dewachter, I., Van Leuven, F.

Volltext

Synthesis and evaluation of two fluorine-18 labelled phenylbenzothiazoles as potential in vivo tracers for amyloid plaque imaging von Serdons, K., Vanderghinste, D., Van Eeckhoudt, M., Borghgraef, P., Kung, H., Van Leuven, F., de Groot, T., Bormans, G., Verbruggen, A.

Volltext

Evaluation of a New Immunoassay to Measure Sirolimus Blood Concentrations Compared to a Tandem Mass-Spectrometric Chromatographic Analysis von Fillée, C., Mourad, M., Squifflet, J.P., Malaise, J., Lerut, J., Reding, R., Borghgraef, P., Vanbinst, R., Wallemacq, P.E.

Volltext

Neurodegeneration and Neuroinflammation in cdk5/p25-Inducible Mice: A Model for Hippocampal Sclerosis and Neocortical Degeneration von Muyllaert, David, Terwel, Dick, Kremer, Anna, Sennvik, Kristina, Borghgraef, Peter, Devijver, Herman, Dewachter, Ilse, Van Leuven, Fred

Volltext

Identification and Isolation of a Hyperphosphorylated, Conformationally Changed Intermediate of Human Protein Tau Expressed in Yeast von Vandebroek, Tom, Vanhelmont, Thomas, Terwel, Dick, Borghgraef, Peter, Lemaire, Katleen, Snauwaert, Johan, Wera, Stefaan, Van Leuven, Fred, Winderickx, Joris

Volltext

Astrocytic calcium/zinc binding protein S100A6 over expression in Alzheimer's disease and in PS1/APP transgenic mice models von Boom, Alain, Pochet, Roland, Authelet, Michele, Pradier, Laurent, Borghgraef, Peter, Van Leuven, Fred, Heizmann, Claus W., Brion, Jean-Pierre

Volltext

beta-site amyloid precursor protein cleaving enzyme 1 increases amyloid deposition in brain parenchyma but reduces cerebrovascular amyloid angiopathy in aging BACE x APP[V717I] dou... von Willem, Michael, Dewachter, Ilse, Smyth, Neil, Van Dooren, Tom, Borghgraef, Peter, Haass, Christian, Van Leuven, Fred

Volltext