Highlight of 2023: The metabolic symphony – orchestrating T‐cell immunity von Booty, Lee M

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NLR in eXile: Emerging roles of NLRX1 in immunity and human disease von Pickering, Robert J., Booty, Lee M.

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Gasdermin D and Beyond – Gasdermin-mediated Pyroptosis in Bacterial Infections von Booty, Lee M., Bryant, Clare E.

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Salmonella Flagellin Activates NAIP/NLRC4 and Canonical NLRP3 Inflammasomes in Human Macrophages von Gram, Anna M, Wright, John A, Pickering, Robert J, Lam, Nathaniel L, Booty, Lee M, Webster, Steve J, Bryant, Clare E

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Macrophage-Derived Extracellular Succinate Licenses Neural Stem Cells to Suppress Chronic Neuroinflammation von Peruzzotti-Jametti, Luca, Bernstock, Joshua D., Vicario, Nunzio, Costa, Ana S.H., Kwok, Chee Keong, Leonardi, Tommaso, Booty, Lee M., Bicci, Iacopo, Balzarotti, Beatrice, Volpe, Giulio, Mallucci, Giulia, Manferrari, Giulia, Donegà, Matteo, Iraci, Nunzio, Braga, Alice, Hallenbeck, John M., Murphy, Michael P., Edenhofer, Frank, Frezza, Christian, Pluchino, Stefano

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Chopping GSDMD: caspase‐8 has joined the team of pyroptosis‐mediating caspases von Gram, Anna M, Booty, Lee M, Bryant, Clare E

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Itaconate is an anti-inflammatory metabolite that activates Nrf2 via alkylation of KEAP1 von Mills, Evanna L., Ryan, Dylan G., Prag, Hiran A., Dikovskaya, Dina, Menon, Deepthi, Zaslona, Zbigniew, Jedrychowski, Mark P., Costa, Ana S. H., Higgins, Maureen, Hams, Emily, Szpyt, John, Runtsch, Marah C., King, Martin S., McGouran, Joanna F., Fischer, Roman, Kessler, Benedikt M., McGettrick, Anne F., Hughes, Mark M., Carroll, Richard G., Booty, Lee M., Knatko, Elena V., Meakin, Paul J., Ashford, Michael L. J., Modis, Louise K., Brunori, Gino, Sévin, Daniel C., Fallon, Padraic G., Caldwell, Stuart T., Kunji, Edmund R. S., Chouchani, Edward T., Frezza, Christian, Dinkova-Kostova, Albena T., Hartley, Richard C., Murphy, Michael P., O’Neill, Luke A.

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Gasdermins assemble; recent developments in bacteriology and pharmacology von Greenwood, Claudine S, Wynosky-Dolfi, Meghan A, Beal, Allison M, Booty, Lee M

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Human rhinovirus promotes STING trafficking to replication organelles to promote viral replication von Triantafilou, Martha, Ramanjulu, Joshi, Booty, Lee M., Jimenez-Duran, Gisela, Keles, Hakan, Saunders, Ken, Nevins, Neysa, Koppe, Emma, Modis, Louise K., Pesiridis, G. Scott, Bertin, John, Triantafilou, Kathy

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Selective Disruption of Mitochondrial Thiol Redox State in Cells and In Vivo von Booty, Lee M., Gawel, Justyna M., Cvetko, Filip, Caldwell, Stuart T., Hall, Andrew R., Mulvey, John F., James, Andrew M., Hinchy, Elizabeth C., Prime, Tracy A., Arndt, Sabine, Beninca, Cristiane, Bright, Thomas P., Clatworthy, Menna R., Ferdinand, John R., Prag, Hiran A., Logan, Angela, Prudent, Julien, Krieg, Thomas, Hartley, Richard C., Murphy, Michael P.

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Integrated metabolic-transcriptomic network identifies immunometabolic modulations in human macrophages von Chen, Hung-Jen, Sévin, Daniel C., Griffith, Guillermo R., Vappiani, Johanna, Booty, Lee M., van Roomen, Cindy P.A.A., Kuiper, Johan, Dunnen, Jeroen den, de Jonge, Wouter J., Prinjha, Rab K., Mander, Palwinder K., Grandi, Paola, Wyspianska, Beata S., de Winther, Menno P.J.

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The mitochondrial dicarboxylate and 2-oxoglutarate carriers do not transport glutathione von Booty, Lee M., King, Martin S., Thangaratnarajah, Chancievan, Majd, Homa, James, Andrew M., Kunji, Edmund R.S., Murphy, Michael P.

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Complement membrane attack complex is an immunometabolic regulator of NLRP3 activation and IL-18 secretion in human macrophages von Jimenez-Duran, Gisela, Kozole, Joseph, Peltier-Heap, Rachel, Dickinson, Eleanor R., Kwiatkowski, Christopher R., Zappacosta, Francesca, Annan, Roland S., Galwey, Nicholas W., Nichols, Eva-Maria, Modis, Louise K., Triantafilou, Martha, Triantafilou, Kathy, Booty, Lee M.

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Ester Prodrugs of Malonate with Enhanced Intracellular Delivery Protect Against Cardiac Ischemia-Reperfusion Injury In Vivo von Prag, Hiran A., Pala, Laura, Kula-Alwar, Duvaraka, Mulvey, John F., Luping, Du, Beach, Timothy E., Booty, Lee M., Hall, Andrew R., Logan, Angela, Sauchanka, Volha, Caldwell, Stuart T., Robb, Ellen L., James, Andrew M., Xu, Zhelong, Saeb-Parsy, Kourosh, Hartley, Richard C., Murphy, Michael P., Krieg, Thomas

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C5aR2 Regulates STING-Mediated Interferon Beta Production in Human Macrophages von Wright, Oliver, Harris, Anna, Nguyen, Van Dien, Zhou, You, Durand, Maxim, Jayyaratnam, Abbie, Gormley, Darren, O'Neill, Luke A J, Triantafilou, Kathy, Nichols, Eva Maria, Booty, Lee M

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Organellar homeostasis and innate immune sensing von Harapas, Cassandra R., Idiiatullina, Elina, Al-Azab, Mahmoud, Hrovat-Schaale, Katja, Reygaerts, Thomas, Steiner, Annemarie, Laohamonthonkul, Pawat, Davidson, Sophia, Yu, Chien-Hsiung, Booty, Lee, Masters, Seth L.

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C5aR2 Regulates STING-Mediated Interferon Beta Production in Human Macrophages von Wright, Oliver, Harris, Anna, Nguyen, Van Dien, Zhou, You, Durand, Maxim, Jayyaratnam, Abbie, Gormley, Darren, O'Neill, Luke AJ, Triantafilou, Kathy, Nichols, Eva Maria, Booty, Lee M

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Chopping GSDMD: caspase-8 has joined the team of pyroptosis-mediating caspases von Gram, Anna M, Booty, Lee M, Bryant, Clare E

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Salmonella flagellin activates NAIP/NLRC4 and canonical NLRP3 inflammasomes in human macrophages von Gram, Anna M, Wright, John A, Pickering, Robert J, Lam, Nathaniel L, Booty, Lee M, Webster, Steve J, Bryant, Clare

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Ester Prodrugs of Malonate with Enhanced Intracellular Delivery Protect Against Cardiac Ischemia-Reperfusion Injury In Vivo von Prag, Hiran A, Pala, Laura, Kula-Alwar, Duvaraka, Mulvey, John F, Luping, Du, Beach, Timothy E, Booty, Lee M, Hall, Andrew R, Logan, Angela, Sauchanka, Volha, Caldwell, Stuart T, Robb, Ellen L, James, Andrew M, Xu, Zhelong, Saeb-Parsy, Kourosh, Hartley, Richard C, Murphy, Michael P, Krieg, Thomas

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