MicroRNAs in Neuroinflammation: Implications in Disease Pathogenesis, Biomarker Discovery and Therapeutic Applications von Slota, Jessy A, Booth, Stephanie A

Volltext

MicroRNA-146a: A Dominant, Negative Regulator of the Innate Immune Response von Saba, Reuben, Sorensen, Debra L, Booth, Stephanie A

Volltext

Single-cell transcriptomics unveils molecular signatures of neuronal vulnerability in a mouse model of prion disease that overlap with Alzheimer’s disease von Slota, Jessy A., Lamoureux, Lise, Frost, Kathy L., Sajesh, Babu V., Booth, Stephanie A.

Volltext

A miRNA signature of prion induced neurodegeneration von Saba, Reuben, Goodman, Chelsey D, Huzarewich, Rhiannon L C H, Robertson, Catherine, Booth, Stephanie A

Volltext

MicroRNA 146a (miR-146a) is over-expressed during prion disease and modulates the innate immune response and the microglial activation state von Saba, Reuben, Gushue, Shantel, Huzarewich, Rhiannon L C H, Manguiat, Kathy, Medina, Sarah, Robertson, Catherine, Booth, Stephanie A

Volltext

MicroRNA-16 targets mRNA involved in neurite extension and branching in hippocampal neurons during presymptomatic prion disease von Burak, Kristyn, Lamoureux, Lise, Boese, Amrit, Majer, Anna, Saba, Reuben, Niu, Yulian, Frost, Kathy, Booth, Stephanie A.

Volltext

Characterization of variably protease-sensitive prionopathy by capillary electrophoresis von Myskiw, Jennifer, Bailey-Elkin, Ben A., Avery, Kristen, Barria, Marcelo A., Ritchie, Diane L., Cohen, Mark L., Appleby, Brian S., Booth, Stephanie A

Volltext

Induction of Multiple miR-200/182 Members in the Brains of Mice Are Associated with Acute Herpes Simplex Virus 1 Encephalitis von Majer, Anna, Caligiuri, Kyle A, Gale, Kamilla K, Niu, Yulian, Phillipson, Clark S, Booth, Timothy F, Booth, Stephanie A

Volltext

DNA vaccination protects mice against Zika virus-induced damage to the testes von Griffin, Bryan D., Muthumani, Kar, Warner, Bryce M., Majer, Anna, Hagan, Mable, Audet, Jonathan, Stein, Derek R., Ranadheera, Charlene, Racine, Trina, De La Vega, Marc-Antoine, Piret, Jocelyne, Kucas, Stephanie, Tran, Kaylie N., Frost, Kathy L., De Graff, Christine, Soule, Geoff, Scharikow, Leanne, Scott, Jennifer, McTavish, Gordon, Smid, Valerie, Park, Young K., Maslow, Joel N., Sardesai, Niranjan Y., Kim, J. Joseph, Yao, Xiao-jian, Bello, Alexander, Lindsay, Robbin, Boivin, Guy, Booth, Stephanie A., Kobasa, Darwyn, Embury-Hyatt, Carissa, Safronetz, David, Weiner, David B., Kobinger, Gary P.

Volltext

MicroRNA and mRNA Dysregulation in Astrocytes Infected with Zika Virus von Kozak, Robert A, Majer, Anna, Biondi, Mia J, Medina, Sarah J, Goneau, Lee W, Sajesh, Babu V, Slota, Jessy A, Zubach, Vanessa, Severini, Alberto, Safronetz, David, Hiebert, Shannon L, Beniac, Daniel R, Booth, Timothy F, Booth, Stephanie A, Kobinger, Gary P

Volltext

Downregulation of circulating miR 802‐5p and miR 194‐5p and upregulation of brain MEF2C along breast cancer brain metastasization von Sereno, Marta, Haskó, János, Molnár, Kinga, Medina, Sarah J., Reisz, Zita, Malhó, Rui, Videira, Mafalda, Tiszlavicz, László, Booth, Stephanie A., Wilhelm, Imola, Krizbai, István A., Brito, Maria Alexandra

Volltext

Early mechanisms of pathobiology are revealed by transcriptional temporal dynamics in hippocampal CA1 neurons of prion infected mice von Majer, Anna, Medina, Sarah J, Niu, Yulian, Abrenica, Bernard, Manguiat, Kathy J, Frost, Kathy L, Philipson, Clark S, Sorensen, Debra L, Booth, Stephanie A

Volltext

Neurons and Astrocytes Elicit Brain Region Specific Transcriptional Responses to Prion Disease in the Murine CA1 and Thalamus von Slota, Jessy A, Medina, Sarah J, Frost, Kathy L, Booth, Stephanie A

Volltext

Generation and Characterization of a SARS-CoV-2-Susceptible Mouse Model Using Adeno-Associated Virus (AAV6.2FF)-Mediated Respiratory Delivery of the Human ACE2 Gene von Tailor, Nikesh, Warner, Bryce M, Griffin, Bryan D, Tierney, Kevin, Moffat, Estella, Frost, Kathy, Vendramelli, Robert, Leung, Anders, Willman, Marnie, Thomas, Sylvia P, Pei, Yanlong, Booth, Stephanie A, Embury-Hyatt, Carissa, Wootton, Sarah K, Kobasa, Darwyn

Volltext

Differentiated cultures of an immortalized human neural progenitor cell line do not replicate prions despite PrPC overexpression von Slota, Jessy A., Wang, Xinzhu, Lusansky, Diana, Medina, Sarah J., Booth, Stephanie A.

Volltext

The cell type resolved mouse transcriptome in neuron-enriched brain tissues from the hippocampus and cerebellum during prion disease von Majer, Anna, Medina, Sarah J., Sorensen, Debra, Martin, Matthew J., Frost, Kathy L., Phillipson, Clark, Manguiat, Kathy, Booth, Stephanie A.

Volltext

Exposure Risk of Chronic Wasting Disease in Humans von Nemani, Satish K., Myskiw, Jennifer L., Lamoureux, Lise, Booth, Stephanie A., Sim, Valerie L.

Volltext

Identification of circulating microRNA signatures as potential biomarkers in the serum of elk infected with chronic wasting disease von Slota, Jessy A., Medina, Sarah J., Klassen, Megan, Gorski, Damian, Mesa, Christine M., Robertson, Catherine, Mitchell, Gordon, Coulthart, Michael B., Pritzkow, Sandra, Soto, Claudio, Booth, Stephanie A.

Volltext

A Novel Triple-Mutant AAV6 Capsid Induces Rapid and Potent Transgene Expression in the Muscle and Respiratory Tract of Mice von van Lieshout, Laura P, Domm, Jakob M, Rindler, Tara N, Frost, Kathy L, Sorensen, Debra L, Medina, Sarah J, Booth, Stephanie A, Bridges, James P, Wootton, Sarah K

Volltext

Dysregulation of neuroprotective astrocytes, a spectrum of microglial activation states, and altered hippocampal neurogenesis are revealed by single-cell RNA sequencing in prion di... von Slota, Jessy A, Sajesh, Babu V, Frost, Kathy F, Medina, Sarah J, Booth, Stephanie A

Volltext