Targeting hypoxia-inducible factor-1, for cancer treatment: Recent advances in developing small-molecule inhibitors from natural compounds von Ma, Zhaowu, Xiang, Xiaoqiang, Li, Shiya, Xie, Peng, Gong, Quan, Goh, Boon-Cher, Wang, Lingzhi

Volltext

Exosomes in Cancer Nanomedicine and Immunotherapy: Prospects and Challenges von Syn, Nicholas L, Wang, Lingzhi, Chow, Edward Kai-Hua, Lim, Chwee Teck, Goh, Boon-Cher

Volltext

Third generation EGFR TKIs: current data and future directions von Tan, Chee-Seng, Kumarakulasinghe, Nesaretnam Barr, Huang, Yi-Qing, Ang, Yvonne Li En, Choo, Joan Rou-En, Goh, Boon-Cher, Soo, Ross A

Volltext

Antitumor Activity of Nivolumab in Recurrent and Metastatic Nasopharyngeal Carcinoma: An International, Multicenter Study of the Mayo Clinic Phase 2 Consortium (NCI-9742) von Ma, Brigette B Y, Lim, Wan-Teck, Goh, Boon-Cher, Hui, Edwin P, Lo, Kwok-Wai, Pettinger, Adam, Foster, Nathan R, Riess, Jonathan W, Agulnik, Mark, Chang, Alex Y C, Chopra, Akhil, Kish, Julie A, Chung, Christine H, Adkins, Douglas R, Cullen, Kevin J, Gitlitz, Barbara J, Lim, Dean W, To, Ka-Fai, Chan, K C Allen, Lo, Y M Dennis, King, Ann D, Erlichman, Charles, Yin, Jun, Costello, Brian A, Chan, Anthony T C

Volltext

Validation of a rapid and sensitive LC-MS/MS method for determination of exemestane and its metabolites, 17β-hydroxyexemestane and 17β-hydroxyexemestane-17-O-β-D-glucuronide: appli... von Wang, Ling-Zhi, Goh, Sok-Hwei, Wong, Andrea Li-Ann, Thuya, Win-Lwin, Lau, Jie-Ying Amelia, Wan, Seow-Ching, Lee, Soo-Chin, Ho, Paul C, Goh, Boon-Cher

Volltext

The potential role of exosomal circRNAs in the tumor microenvironment: insights into cancer diagnosis and therapy von Li, Juan, Zhang, Guo, Liu, Chen-Guang, Xiang, Xiaoqiang, Le, Minh T N, Sethi, Gautam, Wang, Lingzhi, Goh, Boon-Cher, Ma, Zhaowu

Volltext

Comparison of the pharmacokinetics and pharmacodynamics of S‐1 between Caucasian and East Asian patients von Chuah, Benjamin, Goh, Boon‐Cher, Lee, Soo‐Chin, Soong, Richie, Lau, Fayce, Mulay, Marilyn, Dinolfo, Melissa, Lim, Siew‐Eng, Soo, Ross, Furuie, Taro, Saito, Kaku, Zergebel, Christopher, Rosen, Lee S.

Volltext

Targeting STAT3 and oxidative phosphorylation in oncogene-addicted tumors von Lee, Matilda, Hirpara, Jayshree L., Eu, Jie-Qing, Sethi, Gautam, Wang, Lingzhi, Goh, Boon-Cher, Wong, Andrea L.

Volltext

Functional genomics identifies five distinct molecular subtypes with clinical relevance and pathways for growth control in epithelial ovarian cancer von Tan, Tuan Zea, Miow, Qing Hao, Huang, Ruby Yun‐Ju, Wong, Meng Kang, Ye, Jieru, Lau, Jieying Amelia, Wu, Meng Chu, Bin Abdul Hadi, Luqman Hakim, Soong, Richie, Choolani, Mahesh, Davidson, Ben, Nesland, Jahn M., Wang, Ling‐Zhi, Matsumura, Noriomi, Mandai, Masaki, Konishi, Ikuo, Goh, Boon‐Cher, Chang, Jeffrey T., Thiery, Jean Paul, Mori, Seiichi

Volltext

Phase 1 dose escalation multicenter trial of pracinostat alone and in combination with azacitidine in patients with advanced hematologic malignancies von Abaza, Yasmin M., Kadia, Tapan M., Jabbour, Elias J., Konopleva, Marina Y., Borthakur, Gautam, Ferrajoli, Alessandra, Estrov, Zeev, Wierda, William G., Alfonso, Ana, Chong, Toh Han, Chuah, Charles, Koh, Liang‐Piu, Goh, Boon‐Cher, Chang, Julie E., Durkes, Daniel E., Foudray, Maria Cielo, Kantarjian, Hagop M., Dong, Xiao Qin, Garcia‐Manero, Guillermo

Volltext

Exosome-Mediated Metastasis: From Epithelial–Mesenchymal Transition to Escape from Immunosurveillance von Syn, Nicholas, Wang, Lingzhi, Sethi, Gautam, Thiery, Jean-Paul, Goh, Boon-Cher

Volltext

Non-malignant epithelial cells preferentially proliferate from nasopharyngeal carcinoma biopsy cultured under conditionally reprogrammed conditions von Yu, Fenggang, Lu, Yanan, Tao, Lin, Jiang, Yan-Yi, Lin, De-Chen, Wang, Lingzhi, Petersson, Fredrik, Yoshiyama, Hironori, Koeffler, Phillip H., Goh, Boon-Cher, Loh, Kwok Seng

Volltext

A novel combinatorial strategy using seliciclib® and belinostat® for eradication of non-small cell lung cancer via apoptosis induction and BID activation von Ong, Pei-Shi, Wang, Lingzhi, Chia, Deborah Miao-Hui, Seah, Jolyn Yu-Xin, Kong, Li-Ren, Thuya, Win-Lwin, Chinnathambi, Arunachalam, Lau, Jie-Ying Amelia, Wong, Andrea Li-Ann, Yong, Wei-Peng, Yang, Daiwen, Ho, Paul Chi-Lui, Sethi, Gautam, Goh, Boon–Cher

Volltext

Value of a molecular screening program to support clinical trial enrollment in Asian cancer patients: The Integrated Molecular Analysis of Cancer (IMAC) Study von Heong, Valerie, Syn, Nicholas L., Lee, Xiao Wen, Sapari, Nur Sabrina, Koh, Xue Qing, Adam Isa, Zul Fazreen, Sy Lim, Joey, Lim, Diana, Pang, Brendan, Thian, Yee Liang, Ng, Lai Kuan, Wong, Andrea L., Soo, Ross Andrew, Yong, Wei Peng, Chee, Cheng Ean, Lee, Soo‐Chin, Goh, Boon‐Cher, Soong, Richie, Tan, David S.P.

Volltext

Clinical efficacy and biomarker analysis of dual PD-1/CTLA-4 blockade in recurrent/metastatic EBV-associated nasopharyngeal carcinoma von Lim, Darren Wan-Teck, Kao, Hsiang-Fong, Suteja, Lisda, Li, Constance H., Quah, Hong Sheng, Tan, Daniel Shao-Weng, Tan, Sze-Huey, Tan, Eng-Huat, Tan, Wan-Ling, Lee, Justina Nadia, Wee, Felicia Yu-Ting, Jain, Amit, Goh, Boon-Cher, Chua, Melvin L. K., Liao, Bin-Chi, Ng, Quan Sing, Hong, Ruey-Long, Ang, Mei-Kim, Yeong, Joe Poh-Sheng, Iyer, N. Gopalakrishna

Volltext

Repurposing Artemisinin and its Derivatives as Anticancer Drugs: A Chance or Challenge? von Ma, Zhaowu, Woon, Clariis Yi-Ning, Liu, Chen-Guang, Cheng, Jun-Ting, You, Mingliang, Sethi, Gautam, Wong, Andrea Li-Ann, Ho, Paul Chi-Lui, Zhang, Daping, Ong, Peishi, Wang, Lingzhi, Goh, Boon-Cher

Volltext

Clinical translation of patient-derived tumour organoids- bottlenecks and strategies von Foo, Malia Alexandra, You, Mingliang, Chan, Shing Leng, Sethi, Gautam, Bonney, Glenn K, Yong, Wei-Peng, Chow, Edward Kai-Hua, Fong, Eliza Li Shan, Wang, Lingzhi, Goh, Boon-Cher

Volltext

Mechanism-based inhibition of cytochrome P450 3A4 by therapeutic drugs von SHUFENG ZHOU, SUI YUNG CHAN, BOON CHER GOH, ELI CHAN, WEI DUAN, MIN HUANG, MCLEOD, Howard L

Volltext

Genotype-guided versus traditional clinical dosing of warfarin in patients of Asian ancestry: a randomized controlled trial von Syn, Nicholas L, Wong, Andrea Li-Ann, Lee, Soo-Chin, Teoh, Hock-Luen, Yip, James Wei Luen, Seet, Raymond Cs, Yeo, Wee Tiong, Kristanto, William, Bee, Ping-Chong, Poon, L M, Marban, Patrick, Wu, Tuck Seng, Winther, Michael D, Brunham, Liam R, Soong, Richie, Tai, Bee-Choo, Goh, Boon-Cher

Volltext

FAM3C in circulating tumor-derived extracellular vesicles promotes non-small cell lung cancer growth in secondary sites von Thuya, Win Lwin, Kong, Li Ren, Syn, Nicholas L, Ding, Ling-Wen, Cheow, Esther Sok Hwee, Wong, Regina Tong Xin, Wang, Tingting, Goh, Robby Miguel Wen-Jing, Song, Hongyan, Jayasinghe, Migara K, Le, Minh Tn, Hu, Jian Cheng, Yong, Wei-Peng, Lee, Soo-Chin, Wong, Andrea Li-Ann, Sethi, Gautam, Hung, Huynh The, Ho, Paul Chi-Lui, Thiery, Jean-Paul, Sze, Siu Kwan, Guo, Tiannan, Soo, Ross A, Yang, Henry, Lim, Yaw Chyn, Wang, Lingzhi, Goh, Boon-Cher

Volltext