Microphysiological systems in early stage drug development: Perspectives on current applications and future impact von Kopec, Anna K., Yokokawa, Ryuji, Khan, Nasir, Horii, Ikuo, Finley, James E., Bono, Christine P., Donovan, Carol, Roy, Jessica, Harney, Julie, Burdick, Andrew D., Jessen, Bart, Lu, Shuyan, Collinge, Mark, Sadeghian, Ramin Banan, Derzi, Mazin, Tomlinson, Lindsay, Burkhardt, John E.

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Investigation of the binding pocket of human hematopoietic prostaglandin (PG) D2 synthase (hH-PGDS): A tale of two waters von Trujillo, John I., Kiefer, James R., Huang, Wei, Day, Jacqueline E., Moon, Joseph, Jerome, Gina M., Bono, Christine P., Kornmeier, Christine M., Williams, Melanie L., Kuhn, Cyrille, Rennie, Glen R., Wynn, Thomas A., Carron, Christopher P., Thorarensen, Atli

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Human monoclonal antibodies to the insulin-like growth factor 1 receptor inhibit receptor activation and tumor growth in preclinical studies von Runnels, Herbert A., Arbuckle, J. Alan, Bailey, Karen S., Nicastro, Peter J., Sun, Duo, Pegg, Jodi A., Meyer, Debra M., Evans, Michelle, Bono, Christine P., Lie, Wen-Rong, Moffat, Mark A., Casperson, Gerald F., Lennard, Simon, Elvin, John, Vaughan, Tristan, Smith, Christine E., Morton, Phillip A.

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Discovery of an Oral Potent Selective Inhibitor of Hematopoietic Prostaglandin D Synthase (HPGDS) von Carron, Chris P, Trujillo, John I, Olson, Kirk L, Huang, Wei, Hamper, Bruce C, Dice, Tom, Neal, Bradley E, Pelc, Matthew J, Day, Jacqueline E, Rohrer, Douglas C, Kiefer, James R, Moon, Joseph B, Schweitzer, Barbara A, Blake, Tanisha D, Turner, Steve R, Woerndle, Rhonda, Case, Brenda L, Bono, Christine P, Dilworth, Vickie M, Funckes-Shippy, Christie L, Hood, Becky L, Jerome, Gina M, Kornmeier, Christine M, Radabaugh, Melissa R, Williams, Melanie L, Davies, Michael S, Wegner, Craig D, Welsch, Dean J, Abraham, William M, Warren, Chad J, Dowty, Martin E, Hua, Fengmei, Zutshi, Anup, Yang, Jerry Z, Thorarensen, Atli

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Characterization of dendritic cells generated in vivo by an E. coli derived chimeric dual receptor agonist von Kahn, Larry E, Doshi, Parul D, McGarity, Kelly L, Yu, Mingfu, Bono, Christine P, Lie, Wen-Rong, Rankin, Anne M, Smidt, Mary L, Streeter, Philip R, Klein, Barbara K, Welply, Joseph K, Woulfe, Susan L

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Design of MHC class II (DR4) ligands using conformationally restricted imino acids at p3 and p5 von Hanson, Gunnar J., Vuletich, Jennifer L., Bedell, Louis J., Bono, Christine P., Howard, Susan C., Welply, Joseph K., Woulfe, Susan L., Zacheis, Michelle L.

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Negatively charged residues interacting with the p4 pocket confer binding specificity to DRB10401 von Woulfe, Susan L., Bono, Christine P., Zacheis, Michelle L., Kirschmann, Dawn A., Baudino, Troy A., Swearingen, Craig, Karr, Robert W., Schwartz, Benjamin D.

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Clinical Utility of Microarray-Based Gene Expression Profiling in the Diagnosis and Subclassification of Leukemia: Report From the International Microarray Innovations in Leukemia... von HAFERLACH, Torsten, KOHLMANN, Alexander, GILKES, Amanda, CHIARETTI, Sabina, SHURTLEFF, Sheila A, KIPPS, Thomas J, RASSENTI, Laura Z, YEOH, Allen E, PAPENHAUSEN, Peter R, LIU, Wei-Min, WILLIAMS, P. Mickey, FOA, Robin, WIECZOREK, Lothar, BASSO, Giuseppe, TE KRONNIE, Geertruy, BONO, Marie-Christine, DE VOS, John, HERNINDEZ, Jesus M, HOFMANN, Wolf-Karsten, MILLS, Ken I

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Adjuvant Pembrolizumab after Nephrectomy in Renal-Cell Carcinoma von Choueiri, Toni K, Tomczak, Piotr, Park, Se Hoon, Venugopal, Balaji, Ferguson, Thomas, Chang, Yen-Hwa, Hajek, Jaroslav, Symeonides, Stefan N, Lee, Jae Lyun, Sarwar, Naveed, Thiery-Vuillemin, Antoine, Gross-Goupil, Marine, Mahave, Mauricio, Haas, Naomi B, Sawrycki, Piotr, Gurney, Howard, Chevreau, Christine, Melichar, Bohuslav, Kopyltsov, Evgeniy, Alva, Ajjai, Burke, John M, Doshi, Gurjyot, Topart, Delphine, Oudard, Stephane, Hammers, Hans, Kitamura, Hiroshi, Bedke, Jens, Perini, Rodolfo F, Zhang, Pingye, Imai, Kentaro, Willemann-Rogerio, Jaqueline, Quinn, David I, Powles, Thomas

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Immediate versus deferred chemotherapy after radical cystectomy in patients with pT3–pT4 or N+ M0 urothelial carcinoma of the bladder (EORTC 30994): an intergroup, open-label, rand... von Sternberg, Cora N, Dr, Skoneczna, Iwona, MD, Kerst, J Martijn, PhD, Albers, Peter, Prof, Fossa, Sophie D, Prof, Agerbaek, Mads, MD, Dumez, Herlinde, Prof, de Santis, Maria, MD, Théodore, Christine, MD, Leahy, Michael G, Chester, John D, Prof, Verbaeys, Antony, Prof, Daugaard, Gedske, Prof, Wood, Lori, MD, Witjes, J Alfred, PhD, de Wit, Ronald, Prof, Geoffrois, Lionel, MD, Sengelov, Lisa, DMSc, Thalmann, George, Prof, Charpentier, Danielle, MD, Rolland, Frédéric, MD, Mignot, Laurent, MD, Sundar, Santhanam, MRCP, Symonds, Paul, Prof, Graham, John, FRCP, Joly, Florence, Prof, Marreaud, Sandrine, MD, Collette, Laurence, PhD, Sylvester, Richard, ScD

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Analysis and Stability Study of Isoeugenol in Aquaculture Products by Headspace Solid-Phase Microextraction Coupled to Gas Chromatography–Mass Spectrometry von Rafson, Jessica P., Turnipseed, Sherri B., Casey, Christine, De Bono, Amanda, Madson, Mark R.

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CD38 in Advanced Prostate Cancers von Guo, Christina, Crespo, Mateus, Gurel, Bora, Dolling, David, Rekowski, Jan, Sharp, Adam, Petremolo, Antonella, Sumanasuriya, Semini, Rodrigues, Daniel N., Ferreira, Ana, Pereira, Rita, Figueiredo, Ines, Mehra, Niven, Lambros, Maryou B.K., Neeb, Antje, Gil, Veronica, Seed, George, Terstappen, Leon, Alimonti, Andrea, Drake, Charles G., Yuan, Wei, de Bono, Johann S., Robinson, Dan, Van Allen, Eliezer M., Wu, Yi-Mi, Schultz, Nikolaus, Lonigro, Robert J., Mosquera, Juan-Miguel, Montgomery, Bruce, Taplin, Mary-Ellen, Pritchard, Colin C., Attard, Gerhardt, Beltran, Himisha, Abida, Wassim, Bradley, Robert K., Vinson, Jake, Cao, Xuhong, Vats, Pankaj, Kunju, Lakshmi P., Hussain, Maha, Tomlins, Scott A., Cooney, Kathleen A., Smith, David C., Brennan, Christine, Siddiqui, Javed, Mehra, Rohit, Chen, Yu, Rathkopf, Dana E., Morris, Michael J., Solomon, Stephen B., Durack, Jeremy C., Reuter, Victor E., Gopalan, Anuradha, Gao, Jianjiong, Loda, Massimo, Lis, Rosina T., Bowden, Michaela, Balk, Stephen P., Gaviola, Glenn, Sougnez, Carrie, Gupta, Manaswi, Yu, Evan Y., Mostaghel, Elahe A., Cheng, Heather H., Mulcahy, Hyojeong, True, Lawrence D., Plymate, Stephen R., Dvinge, Heidi, Ferraldeschi, Roberta, Flohr, Penny, Miranda, Susana, Zafeiriou, Zafeiris, Tunariu, Nina, Mateo, Joaquin, Perez-Lopez, Raquel, Demichelis, Francesca, Robinson, Brian D., Schiffman, Marc, Nanus, David M., Tagawa, Scott T., Sigaras, Alexandros, Eng, Kenneth W., Elemento, Olivier, Sboner, Andrea, Heath, Elisabeth I., Scher, Howard I., Pienta, Kenneth J., Kantoff, Philip, de Bono, Johann S., Rubin, Mark A., Nelson, Peter S., Garraway, Levi A., Sawyers, Charles L., Chinnaiyan, Arul M.

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Overall Survival with Adjuvant Pembrolizumab in Renal-Cell Carcinoma von Choueiri, Toni K., Tomczak, Piotr, Park, Se Hoon, Venugopal, Balaji, Ferguson, Tom, Symeonides, Stefan N., Hajek, Jaroslav, Chang, Yen-Hwa, Lee, Jae-Lyun, Sarwar, Naveed, Haas, Naomi B., Gurney, Howard, Sawrycki, Piotr, Mahave, Mauricio, Gross-Goupil, Marine, Zhang, Tian, Burke, John M., Doshi, Gurjyot, Melichar, Bohuslav, Kopyltsov, Evgeniy, Alva, Ajjai, Oudard, Stephane, Topart, Delphine, Hammers, Hans, Kitamura, Hiroshi, McDermott, David F., Silva, Adriano, Winquist, Eric, Cornell, Jerry, Elfiky, Aymen, Burgents, Joseph E., Perini, Rodolfo F., Powles, Thomas

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Integrative Clinical Genomics of Advanced Prostate Cancer von Robinson, Dan, Van Allen, Eliezer M., Wu, Yi-Mi, Schultz, Nikolaus, Lonigro, Robert J., Mosquera, Juan-Miguel, Montgomery, Bruce, Taplin, Mary-Ellen, Pritchard, Colin C., Attard, Gerhardt, Beltran, Himisha, Abida, Wassim, Bradley, Robert K., Vinson, Jake, Cao, Xuhong, Vats, Pankaj, Kunju, Lakshmi P., Hussain, Maha, Feng, Felix Y., Tomlins, Scott A., Cooney, Kathleen A., Smith, David C., Brennan, Christine, Siddiqui, Javed, Mehra, Rohit, Chen, Yu, Rathkopf, Dana E., Morris, Michael J., Solomon, Stephen B., Durack, Jeremy C., Reuter, Victor E., Gopalan, Anuradha, Gao, Jianjiong, Loda, Massimo, Lis, Rosina T., Bowden, Michaela, Balk, Stephen P., Gaviola, Glenn, Sougnez, Carrie, Gupta, Manaswi, Yu, Evan Y., Mostaghel, Elahe A., Cheng, Heather H., Mulcahy, Hyojeong, True, Lawrence D., Plymate, Stephen R., Dvinge, Heidi, Ferraldeschi, Roberta, Flohr, Penny, Miranda, Susana, Zafeiriou, Zafeiris, Tunariu, Nina, Mateo, Joaquin, Perez-Lopez, Raquel, Demichelis, Francesca, Robinson, Brian D., Sboner, Andrea, Schiffman, Marc, Nanus, David M., Tagawa, Scott T., Sigaras, Alexandros, Eng, Kenneth W., Elemento, Olivier, Heath, Elisabeth I., Scher, Howard I., Pienta, Kenneth J., Kantoff, Philip, de Bono, Johann S., Rubin, Mark A., Nelson, Peter S., Garraway, Levi A., Sawyers, Charles L., Chinnaiyan, Arul M.

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ERF mutations reveal a balance of ETS factors controlling prostate oncogenesis von Bose, Rohit, Karthaus, Wouter R., Armenia, Joshua, Abida, Wassim, Iaquinta, Phillip J., Zhang, Zeda, Wongvipat, John, Wasmuth, Elizabeth V., Shah, Neel, Sullivan, Patrick S., Doran, Michael G., Wang, Ping, Patruno, Anna, Zhao, Yilin, Zheng, Deyou, Schultz, Nikolaus, Sawyers, Charles L.

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Author Correction: Common and rare variant association analyses in amyotrophic lateral sclerosis identify 15 risk loci with distinct genetic architectures and neuron-specific biolo... von Bakker, Mark K., van Vugt, Joke J. F. A., Hop, Paul J., Westra, Harm-Jan, Deelen, Patrick, Hannon, Eilis, Dolzhenko, Egor, Westeneng, Henk-Jan, Tazelaar, Gijs H. P., van Eijk, Kristel R., Kooyman, Maarten, Byrne, Ross P., Doherty, Mark, Heverin, Mark, Al Khleifat, Ahmad, Iacoangeli, Alfredo, Shatunov, Aleksey, Smith, Bradley N., Chandran, Siddharthan, Pal, Suvankar, Morrison, Karen E., Shaw, Pamela J., Hardy, John, Sendtner, Michael, Meyer, Thomas, Başak, Nazli, van der Kooi, Anneke J., Ratti, Antonia, Fogh, Isabella, Lauria, Giuseppe, Corti, Stefania, Sorarù, Gianni, Filosto, Massimiliano, Chiò, Adriano, Calvo, Andrea, Brunetti, Maura, Nefussy, Beatrice, Osmanovic, Alma, Lerner, Yossef, Gotkine, Marc, Bell, Shaughn, Vourc’h, Patrick, Corcia, Philippe, Salachas, François, Mora Pardina, Jesus S., Rojas-García, Ricardo, Ross, Jay P., Weishaupt, Jochen H., Brenner, David, Bensimon, Gilbert, Payan, Christine A. M., Saker-Delye, Safa, Wood, Nicholas W., Rademakers, Rosa, Lieb, Wolfgang, Olsen, Catherine M., Uitterlinden, Andre G., Hofman, Albert, Rietschel, Marcella, Traynor, Bryan J., Mitne Neto, Miguel, Cauchi, Ruben J., Gaur, Nayana, Ilse, Benjamin, Stubendorff, Beatrice, Witte, Otto W., Steinbach, Robert, Graff, Caroline, Ataulina, Anastasia, Rogelj, Boris, Koritnik, Blaž, Zidar, Janez, Ravnik-Glavač, Metka, Glavač, Damjan, Stević, Zorica, Drory, Vivian, Povedano, Monica, Blair, Ian P., Kiernan, Matthew C., Furlong, Sarah, Mathers, Susan, Nicholson, Garth A., Pamphlett, Roger, Rowe, Dominic B., Williams, Kelly L., Mather, Karen A., Sachdev, Perminder S., Wallace, Leanne, Pinto, Susana, Rouleau, Guy A., Breen, Gerome, Brown, Robert H., Andersen, Peter M., McRae, Allan F., Davey Smith, George, Gaunt, Tom R., Eberle, Michael A., Wray, Naomi R., Van Damme, Philip, Veldink, Jan H.

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An international expanded-access programme of everolimus: Addressing safety and efficacy in patients with metastatic renal cell carcinoma who progress after initial vascular endoth... von Grünwald, Viktor, Karakiewicz, Pierre I, Bavbek, Sevil E, Miller, Kurt, Machiels, Jean-Pascal, Lee, Se-Hoon, Larkin, James, Bono, Petri, Rha, Sun Young, Castellano, Daniel, Blank, Christian U, Knox, Jennifer J, Hawkins, Robert, Anak, Oezlem, Rosamilia, Marianne, Booth, Jocelyn, Pirotta, Nicoletta, Bodrogi, István

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Viable Malignant Cells After Primary Chemotherapy for Disseminated Nonseminomatous Germ Cell Tumors: Prognostic Factors and Role of Postsurgery Chemotherapy—Results From an Interna... von FIZAZI, Karim, TJULANDIN, Sergei, STENNING, Sally, HORWICH, Alan, PONT, Jörg, ALBERS, Peter, DE GIORGI, Ugo, BOWER, Mark, BULANOV, Anatoly, PIZZOCARO, Giorgio, APARICIO, Jorge, NICHOLS, Craig R, SALVIONI, Roberto, THEODORE, Christine, HARTMANN, Jörg Thomas, SCHMOLL, Hans-Joachim, KAYE, Stanley B, CULINE, Stéphane, DROZ, Jean-Pierre, MAHE, Cedric, GERMA-LLUCH, José R, BOUZY, Jeannine, RAGAN, David, BOKEMEYER, Carsten, GERL, Arthur, FLECHON, Aude, DE BONO, Johann S

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Targeting a complex transcriptome: the construction of the mouse full-length cDNA encyclopedia von Carninci, Piero, Waki, Kazunori, Shiraki, Toshiyuki, Konno, Hideaki, Shibata, Kazuhiro, Itoh, Masayoshi, Aizawa, Katsunori, Arakawa, Takahiro, Ishii, Yoshiyuki, Sasaki, Daisuke, Bono, Hidemasa, Kondo, Shinji, Sugahara, Yuichi, Saito, Rintaro, Osato, Naoki, Fukuda, Shiro, Sato, Kenjiro, Watahiki, Akira, Hirozane-Kishikawa, Tomoko, Nakamura, Mari, Shibata, Yuko, Yasunishi, Ayako, Kikuchi, Noriko, Yoshiki, Atsushi, Kusakabe, Moriaki, Gustincich, Stefano, Beisel, Kirk, Pavan, William, Aidinis, Vassilis, Nakagawara, Akira, Held, William A, Iwata, Hiroo, Kono, Tomohiro, Nakauchi, Hiromitsu, Lyons, Paul, Wells, Christine, Hume, David A, Fagiolini, Michela, Hensch, Takao K, Brinkmeier, Michelle, Camper, Sally, Hirota, Junji, Mombaerts, Peter, Muramatsu, Masami, Okazaki, Yasushi, Kawai, Jun, Hayashizaki, Yoshihide

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Continued discovery of transcriptional units expressed in cells of the mouse mononuclear phagocyte lineage von Wells, Christine A, Ravasi, Timothy, Sultana, Razvan, Yagi, Ken, Carninci, Piero, Bono, Hidemasa, Faulkner, Geoffrey, Okazaki, Yasushi, Quackenbush, John, Hume, David A, Lyons, Paul A

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