Histone H2AX phosphorylation is dispensable for the initial recognition of DNA breaks von Celeste, Arkady, Fernandez-Capetillo, Oscar, Kruhlak, Michael J., Pilch, Duane R., Staudt, David W., Lee, Alicia, Bonner, Robert F., Bonner, William M., Nussenzweig, André

Volltext

Senescing human cells and ageing mice accumulate DNA lesions with unrepairable double-strand breaks von Sedelnikova, Olga A., Horikawa, Izumi, Zimonjic, Drazen B., Popescu, Nicholas C., Bonner, William M., Barrett, J. Carl

Volltext

Distribution and Dynamics of Chromatin Modification Induced by a Defined DNA Double-Strand Break von Shroff, Robert, Arbel-Eden, Ayelet, Pilch, Duane, Ira, Grzegorz, Bonner, William M., Petrini, John H., Haber, James E., Lichten, Michael

Volltext

A critical role for histone H2AX in recruitment of repair factors to nuclear foci after DNA damage von Paull, Tanya T, Rogakou, Emmy P, Yamazaki, Vikky, Kirchgessner, Cordula U, Gellert, Martin, Bonner, William M

Volltext

Low-Dose Radiation: Thresholds, Bystander Effects, and Adaptive Responses von Bonner, William M.

Volltext

Megabase Chromatin Domains Involved in DNA Double-Strand Breaks in vivo von Rogakou, Emmy P., Boon, Chye, Redon, Christophe, Bonner, William M.

Volltext

Quantitative detection of (125)IdU-induced DNA double-strand breaks with gamma-H2AX antibody von Sedelnikova, Olga A, Rogakou, Emmy P, Panyutin, Igor G, Bonner, William M

Volltext

H2AX Haploinsufficiency Modifies Genomic Stability and Tumor Susceptibility von Celeste, Arkady, Difilippantonio, Simone, Difilippantonio, Michael J., Fernandez-Capetillo, Oscar, Pilch, Duane R., Sedelnikova, Olga A., Eckhaus, Michael, Ried, Thomas, Bonner, William M., Nussenzweig, André

Volltext

H2AX Is Required for Chromatin Remodeling and Inactivation of Sex Chromosomes in Male Mouse Meiosis von Fernandez-Capetillo, Oscar, Mahadevaiah, Shantha K., Celeste, Arkady, Romanienko, Peter J., Camerini-Otero, R.Daniel, Bonner, William M., Manova, Katia, Burgoyne, Paul, Nussenzweig, André

Volltext

Genomic Instability in Mice Lacking Histone H2AX von Celeste, Arkady, Petersen, Simone, Romanienko, Peter J., Fernandez-Capetillo, Oscar, Chen, Hua Tang, Sedelnikova, Olga A., Bernardo Reina-San-Martin, Coppola, Vincenzo, Meffre, Eric, Difilippantonio, Michael J., Redon, Christophe, Pilch, Duane R., Olaru, Alexandru, Eckhaus, Michael, Camerini-Otero, R. Daniel, Tessarollo, Lino, Livak, Ferenc, Manova, Katia, Bonner, William M., Nussenzweig, Michel C., Nussenzweig, André

Volltext

Recombinational DNA double-strand breaks in mice precede synapsis von Mahadevaiah, Shantha K., Turner, James M.A., Baudat, Frédéric, Rogakou, Emmy P., de Boer, Peter, Blanco-Rodríguez, Josefa, Jasin, Maria, Keeney, Scott, Bonner, William M., Burgoyne, Paul S.

Volltext

Initiation of DNA Fragmentation during Apoptosis Induces Phosphorylation of H2AX Histone at Serine 139 von Rogakou, Emmy P., Nieves-Neira, Wilberto, Boon, Chye, Pommier, Yves, Bonner, William M.

Volltext

Ionizing radiation induces DNA double-strand breaks in bystander primary human fibroblasts von Sokolov, Mykyta V, Smilenov, Lubomir B, Hall, Eric J, Panyutin, Igor G, Bonner, William M, Sedelnikova, Olga A

Volltext

Phosphorylation of Histone H2AX and Activation of Mre11, Rad50, and Nbs1 in Response to Replication-dependent DNA Double-strand Breaks Induced by Mammalian DNA Topoisomerase I Clea... von Furuta, Takahisa, Takemura, Haruyuki, Liao, Zhi-Yong, Aune, Gregory J., Redon, Christophe, Sedelnikova, Olga A., Pilch, Duane R., Rogakou, Emmy P., Celeste, Arkady, Chen, Hua Tang, Nussenzweig, Andre, Aladjem, Mirit I., Bonner, William M., Pommier, Yves

Volltext

Histone H2AX in DNA damage and repair von Sedelnikova, Olga A, Pilch, Duane R, Redon, Christophe, Bonner, William M

Volltext

γ-H2AX Detection in Peripheral Blood Lymphocytes, Splenocytes, Bone Marrow, Xenografts, and Skin von Redon, Christophe E., Nakamura, Asako J., Sordet, Olivier, Dickey, Jennifer S., Gouliaeva, Ksenia, Tabb, Brian, Lawrence, Scott, Kinders, Robert J., Bonner, William M., Sedelnikova, Olga A.

Volltext

AID is required to initiate Nbs1/γ-H2AX focus formation and mutations at sites of class switching von Petersen, Simone, Casellas, Rafael, Reina-San-Martin, Bernardo, Chen, Hua Tang, Difilippantonio, Michael J., Wilson, Patrick C., Hanitsch, Leif, Celeste, Arkady, Muramatsu, Masamichi, Pilch, Duane R., Redon, Christophe, Ried, Thomas, Bonner, William M., Honjo, Tasuku, Nussenzweig, Michel C., Nussenzweig, André

Volltext

Yeast histone 2A serine 129 is essential for the efficient repair of checkpoint-blind DNA damage von Redon, Christophe, Pilch, Duane R, Rogakou, Emmy P, Orr, Ann H, Lowndes, Noel F, Bonner, William M

Volltext

UV-Induced Replication Arrest in the Xeroderma Pigmentosum Variant Leads to DNA Double-Strand Breaks, γ-H2AX Formation, and Mre11 Relocalization von Limoli, Charles L., Giedzinski, Erich, Bonner, William M., Cleaver, James E.

Volltext

Accumulation of oxidatively induced clustered DNA lesions in human tumor tissues von Nowsheen, Somaira, Wukovich, Rebecca L., Aziz, Khaled, Kalogerinis, Peter T., Richardson, Christopher C., Panayiotidis, Mihalis I., Bonner, William M., Sedelnikova, Olga A., Georgakilas, Alexandros G.

Volltext