Efficacy and Pharmacology of the NLRP3 Inflammasome Inhibitor CP-456,773 (CRID3) in Murine Models of Dermal and Pulmonary Inflammation von Primiano, Michael J, Lefker, Bruce A, Bowman, Michael R, Bree, Andrea G, Hubeau, Cedric, Bonin, Paul D, Mangan, Matthew, Dower, Ken, Monks, Brian G, Cushing, Leah, Wang, Stephen, Guzova, Julia, Jiao, Aiping, Lin, Lih-Ling, Latz, Eicke, Hepworth, David, Hall, J Perry

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Evaluating the Role of Multidrug Resistance Protein 3 (MDR3) Inhibition in Predicting Drug-Induced Liver Injury Using 125 Pharmaceuticals von Aleo, Michael D, Shah, Falgun, He, Kan, Bonin, Paul D, Rodrigues, A. David

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PF-1355, a mechanism-based myeloperoxidase inhibitor, prevents immune complex vasculitis and anti-glomerular basement membrane glomerulonephritis von Zheng, Wei, Warner, Roscoe, Ruggeri, Roger, Su, Chunyan, Cortes, Christian, Skoura, Athanasia, Ward, Jessica, Ahn, Kay, Kalgutkar, Amit, Sun, Dexue, Maurer, Tristan S, Bonin, Paul D, Okerberg, Carlin, Bobrowski, Walter, Kawabe, Thomas, Zhang, Yanwei, Coskran, Timothy, Bell, Sammy, Kapoor, Bhupesh, Johnson, Kent, Buckbinder, Leonard

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Cryo-EM structures of the human glutamine transporter SLC1A5 (ASCT2) in the outward-facing conformation von Yu, Xiaodi, Plotnikova, Olga, Bonin, Paul D, Subashi, Timothy A, McLellan, Thomas J, Dumlao, Darren, Che, Ye, Dong, Yin Yao, Carpenter, Elisabeth P, West, Graham M, Qiu, Xiayang, Culp, Jeffrey S, Han, Seungil

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Preliminary Effects of a Structured Educational Program in Cardiac Patients at Different Stages of Enrollment in Cardiovascular Rehabilitation von Zulianello dos Santos, Rafaella, Scheafer Korbes, Andrea, Batista Bonin, Christiani D., Marques Vieira, Ariany, Karsten, Marlus, Benetti, Magnus, Oh, Paul, Ghisi, Gabriela L. d. M.

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Optogenetic stimulation of VTA dopamine neurons reveals that tonic but not phasic patterns of dopamine transmission reduce ethanol self-administration von Bass, Caroline E, Grinevich, Valentina P, Gioia, Dominic, Day-Brown, Jonathan D, Bonin, Keith D, Stuber, Garret D, Weiner, Jeff L, Budygin, Evgeny A

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Optogenetic control of striatal dopamine release in rats von Bass, Caroline E, Grinevich, Valentina P, Vance, Zachary B, Sullivan, Ryan P, Bonin, Keith D, Budygin, Evgeny A

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Human drug‐induced liver injury severity is highly associated with dual inhibition of liver mitochondrial function and bile salt export pump von Aleo, Michael D., Luo, Yi, Swiss, Rachel, Bonin, Paul D., Potter, David M., Will, Yvonne

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Aversive stimulus differentially triggers subsecond dopamine release in reward regions von Budygin, E.A, Park, J, Bass, C.E, Grinevich, V.P, Bonin, K.D, Wightman, R.M

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Opposite Consequences of Tonic and Phasic Increases in Accumbal Dopamine on Alcohol-Seeking Behavior von Budygin, Evgeny A., Bass, Caroline E., Grinevich, Valentina P., Deal, Alex L., Bonin, Keith D., Weiner, Jeff L.

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Infrastructures de transport créatives: Mieux les intégrer aux écosystèmes, paysages et territoires

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Terminal effects of optogenetic stimulation on dopamine dynamics in rat striatum von Bass, Caroline E., Grinevich, Valentina P., Kulikova, Alexandra D., Bonin, Keith D., Budygin, Evgeny A.

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Activation of the G-Protein-Coupled Receptor 119: A Conformation-Based Hypothesis for Understanding Agonist Response von McClure, Kim F, Darout, Etzer, Guimarães, Cristiano R. W, DeNinno, Michael P, Mascitti, Vincent, Munchhof, Michael J, Robinson, Ralph P, Kohrt, Jeffrey, Harris, Anthony R, Moore, Dianna E, Li, Bryan, Samp, Lacey, Lefker, Bruce A, Futatsugi, Kentaro, Kung, Daniel, Bonin, Paul D, Cornelius, Peter, Wang, Ruduan, Salter, Eben, Hornby, Sam, Kalgutkar, Amit S, Chen, Yue

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Phase I study of PF‐04895162, a Kv7 channel opener, reveals unexpected hepatotoxicity in healthy subjects, but not rats or monkeys: clinical evidence of disrupted bile acid homeost... von Aleo, Michael D., Aubrecht, Jiri, D. Bonin, Paul, Burt, Deborah A., Colangelo, Jennifer, Luo, Lina, Schomaker, Shelli, Swiss, Rachel, Kirby, Simon, C. Rigdon, Greg, Dua, Pinky

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Light torque nanocontrol, nanomotors and nanorockers von Bonin, Keith, Kourmanov, Bakhit, Walker, Thad

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Oxidative Metabolism of a Quinoxaline Derivative by Xanthine Oxidase in Rodent Plasma von Sharma, Raman, Eng, Heather, Walker, Gregory S, Barreiro, Gabriela, Stepan, Antonia F, McClure, Kim F, Wolford, Angela, Bonin, Paul D, Cornelius, Peter, Kalgutkar, Amit S

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Synthesis and SAR of 1,2,3,4-tetrahydroisoquinolin-1-ones as novel G-protein-coupled receptor 40 (GPR40) antagonists von Humphries, Paul S., Benbow, John W., Bonin, Paul D., Boyer, David, Doran, Shawn D., Frisbie, Richard K., Piotrowski, David W., Balan, Gayatri, Bechle, Bruce M., Conn, Edward L., Dirico, Kenneth J., Oliver, Robert M., Soeller, Walter C., Southers, James A., Yang, Xiaojing

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Bidirectional Control of Alcohol-drinking Behaviors Through Locus Coeruleus Optoactivation von Deal, Alex L., Bass, Caroline E., Grinevich, Valentina P., Delbono, Osvaldo, Bonin, Keith D., Weiner, Jeff L., Budygin, Evgeny A.

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Optogenetically-induced tonic dopamine release from VTA-nucleus accumbens projections inhibits reward consummatory behaviors von Mikhailova, Maria A, Bass, Caroline E, Grinevich, Valentina P, Chappell, Ann M, Deal, Alex L, Bonin, Keith D, Weiner, Jeff L, Gainetdinov, Raul R, Budygin, Evgeny A

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Design and evaluation of a 2-(2,3,6-trifluorophenyl)acetamide derivative as an agonist of the GPR119 receptor von Mascitti, Vincent, Stevens, Benjamin D., Choi, Chulho, McClure, Kim F., Guimarães, Cristiano R.W., Farley, Kathleen A., Munchhof, Michael J., Robinson, Ralph P., Futatsugi, Kentaro, Lavergne, Sophie Y., Lefker, Bruce A., Cornelius, Peter, Bonin, Paul D., Kalgutkar, Amit S., Sharma, Raman, Chen, Yue

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